Rheumatology
Phase 2 RCT | Efficacy and safety of low-dose Interleukin 2 for primary Sjögren syndrome.
17 Nov, 2022 | 12:20h | UTCCommentary: Sjogren’s Responds to Cytokine Treatment, Early Data Show — Phase II trial signals possible breakthrough for hard-to-treat illness – MedPage Today (free registration required)
RCT | In patients with end-stage ankle osteoarthritis, total ankle replacement and arthrodesis resulted in comparable results.
16 Nov, 2022 | 13:45h | UTCTotal Ankle Replacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
News Release: Trial shows benefits of two forms of ankle surgery for osteoarthritis – University College London
Summary for Patients: Total Ankle Replacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis
2022 EULAR recommendations for screening and prophylaxis of chronic and opportunistic infections in rheumatic diseases.
15 Nov, 2022 | 12:55h | UTC
Commentary on Twitter
https://twitter.com/ARD_BMJ/status/1590254371257946112
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological DMARDs.
15 Nov, 2022 | 12:53h | UTCCommentary: Updated EULAR recommendations on the use of DMARDs for people with RA – News Medical
RCT | Genicular nerve block offers short-term pain relief in patients with knee osteoarthritis.
15 Nov, 2022 | 12:50h | UTCCommentary: Genicular nerve block may provide short-term pain relief for knee osteoarthritis – medwire News
Matched cohort study | Long-term clinical and radiographic outcomes in patients with clinically isolated aortitis.
11 Nov, 2022 | 13:43h | UTC
M-A | Cardiovascular safety of febuxostat and allopurinol in patients with gout.
11 Nov, 2022 | 13:41h | UTC
Cohort Study | Study shows subclinical Hyperthyroidism is linked to an increased risk of fractures.
10 Nov, 2022 | 14:08h | UTCAssociation Between Subclinical Thyroid Dysfunction and Fracture Risk – JAMA Network Open
Commentary: Does Subclinical Hyperthyroidism Raise Fracture Risk? – Medscape (free registration required)
Commentary on Twitter
Subclinical hyperthyroidism may be an independent risk factor associated with fracture, highlighting a potential role for more aggressive screening and monitoring to prevent bone mineral disease. #OAReasearch https://t.co/LQVjaNU1zM
— JAMA Network Open (@JAMANetworkOpen) November 8, 2022
Cohort Study | Systemic lupus erythematosus low disease activity and mortality risk.
10 Nov, 2022 | 13:48h | UTCLupus low disease activity state and remission and risk of mortality in patients with systemic lupus erythematosus: a prospective, multinational, longitudinal cohort study – The Lancet Rheumatology (link to abstract – $ for full-text)
Commentary on Twitter
NEW RESEARCH—Lupus low disease activity state (#LLDAS) significantly reduced the risk of mortality in patients with #SLE; remission did not further reduce the risk of mortality unless lower glucocorticoid thresholds were used https://t.co/xYqzQME3li #LupusAwarenessMonth pic.twitter.com/gtLTKn92Go
— The Lancet Rheumatology (@TheLancetRheum) October 24, 2022
M-A | DOACs increase the risk of arterial thrombosis vs. Vitamin-K antagonists in antiphospholipid syndrome.
9 Nov, 2022 | 12:28h | UTCDirect Oral Anticoagulants vs Vitamin-K Antagonists in Thrombotic Antiphospholipid Syndrome: Meta-analysis of Randomized Controlled Trials – Journal of the American College of Cardiology (link to abstract – $ for full-text)
SR | Efficacy and safety of IL-6 inhibition with biological DMARDs in immune-mediated inflammatory diseases.
8 Nov, 2022 | 11:47h | UTC
Commentary on Twitter
Check out our latest systematic literature review on IL-6 inhibition in immune-mediated inflammatory diseases:
▶️ positive clinical in a group of diseases
▶️ benefits in #COVID-19
▶️ similar safety outcomes vs other bDMARDs🔗 https://t.co/N1S9H2NrLQ pic.twitter.com/IAFGoEgkrY
— Annals of the Rheumatic Diseases (@eular_ARD) September 29, 2022
Guideline on prescribing drugs in pregnancy and breastfeeding: comorbidity medications used in rheumatology practice.
4 Nov, 2022 | 13:42h | UTCExecutive Summary: British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: comorbidity medications used in rheumatology practice – Rheumatology
Guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids.
4 Nov, 2022 | 13:44h | UTCExecutive Summary: British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids – Rheumatology
Recommendations for the screening, monitoring, and treatment of juvenile idiopathic arthritis-associated uveitis.
3 Nov, 2022 | 14:01h | UTC
SR | Non‐biologic, steroid‐sparing therapies for non‐infectious intermediate, posterior, and panuveitis in adults.
3 Nov, 2022 | 13:40h | UTCSummary: Treatment of inflammatory conditions of the eye with medications – Cochrane Library
Narrative review of machine learning in rheumatic and musculoskeletal diseases: biases, goals, and future directions.
3 Nov, 2022 | 13:34h | UTC
NICE Guideline | Osteoarthritis in over 16s: diagnosis and management.
2 Nov, 2022 | 14:29h | UTC
Global epidemiology of systemic lupus erythematosus: a comprehensive systematic analysis and modelling study.
2 Nov, 2022 | 14:21h | UTCCommentary: SLE Rates Vary Worldwide and Require Further Study, Study Emphasizes – AJMC
EULAR points to consider to support people with rheumatic and musculoskeletal diseases in work participation.
2 Nov, 2022 | 14:20h | UTCNews Release: Supporting workers with rheumatic and musculoskeletal diseases – European Alliance of Associations for Rheumatology
M-A | Collagenase clostridium histolyticum injections vs. percutaneous needle fasciotomy vs. limited fasciectomy in the Dupuytren’s contracture.
1 Nov, 2022 | 12:05h | UTC
ACR/EULAR remission criteria for rheumatoid arthritis: 2022 Revision.
26 Oct, 2022 | 14:39h | UTCCommentary: New ACR/EULAR Guideline Expands RA Remission Definition – MedPage Today (free registration required)
ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update.
26 Oct, 2022 | 14:38h | UTC
Optimizing medication use in older adults with rheumatic diseases: deprescribing as an approach when less may be more.
26 Oct, 2022 | 14:33h | UTCRelated:
Antihypertensive Deprescribing in Older Adults: a Practical Guide – Current Hypertension Reports
Deprescribing in Palliative Cancer Care – Life
Less is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360
Polypharmacy Management in Older Patients – Mayo Clinic Proceedings
Eliminating Medication Overload: A National Action Plan – Lown Institute
Common ED Medication Errors: Polypharmacy – emDocs
Current and future perspectives on the management of polypharmacy – BMC Family Practice
Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international
Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety
RCT | Recapture and retreatment rates with ixekizumab after withdrawal of therapy in patients with axial spondyloarthritis.
25 Oct, 2022 | 13:19h | UTCCommentary: Successful retreatment of axSpA flare feasible following ixekizumab withdrawal – medwire News
Systematic Review | Systemic corticosteroids for radicular and non‐radicular low back pain.
24 Oct, 2022 | 14:03h | UTCSystemic corticosteroids for radicular and non‐radicular low back pain – Cochrane Library