Rheumatology

Study: Local Anesthetic With or Without Corticosteroid for Lumbar Spinal Stenosis

26 Aug, 2017 | 16:22h | UTC

Long-Term Effects of Repeated Injections of Local Anesthetic With or Without Corticosteroid for Lumbar Spinal Stenosis: A Randomized Trial – Archives of Physical Medicine and Rehabilitation (free)

Source: ACP Journal Wise ($)

“Epidural injections of corticosteroid plus lidocaine offered no benefits from 6 weeks to 12 months beyond that of injections of lidocaine alone”

Guideline: use of imaging in the clinical management of peripheral joint osteoarthritis

24 Aug, 2017 | 23:09h | UTC

EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis – Annals of Rheumatic Diseases (free)

Guideline: EULAR recommendations for the treatment of systemic sclerosis

24 Aug, 2017 | 20:36h | UTC

Update of EULAR recommendations for the treatment of systemic sclerosis – Annals of Rheumatic Diseases (free)

Study: Weight Loss Associated with Less Progression of Changes in Knee Articular Cartilage

22 Aug, 2017 | 19:58h | UTC

Is Weight Loss Associated with Less Progression of Changes in Knee Articular Cartilage among Obese and Overweight Patients as Assessed with MR Imaging over 48 Months? Data from the Osteoarthritis Initiative – Radiology (free)

Commentaries: Weight Loss Can Slow Down Knee Joint Degeneration – RSNA Press Release (free) AND Osteoarthritis: Knee joint degeneration slowed with weight loss, study confirms – Medical News Today (free)

Systematic Review: Benefits and Harms of Osteoporosis Medications in Patients With Chronic Kidney Disease

22 Aug, 2017 | 15:32h | UTC

Benefits and Harms of Osteoporosis Medications in Patients With Chronic Kidney Disease: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Benefits and harms of osteoporosis medications unclear for patients with CKD – Medical News Today (free) AND Benefits and harms of osteoporosis medications unclear for patients with CKD – 2 Minute Medicine (free)

Source: ACP Journal Club ($)

Study: Uric acid and incident dementia

22 Aug, 2017 | 00:55h | UTC

Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study – Annals of Rheumatic Diseases (link to abstract – $ for full-text)

Commentaries: Elevated Uric Acid Linked to Dementia in the Elderly – MedPage Today (free registration required) AND Dementia risk may be higher in elderly patients with high serum uric acid levels – ACP Internist (free)

When Sports Injuries Lead to Arthritis in Joints

21 Aug, 2017 | 01:34h | UTC

When Sports Injuries Lead to Arthritis in Joints – The New York Times (10 articles per month are free)

Benefits and safety of gabapentinoids in chronic low back pain

16 Aug, 2017 | 23:04h | UTC

Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials – PLOS Medicine (free)

Commentaries: Gabapentinoids Seem to Offer Little Benefit, Substantial Risks in Low Back Pain – Physician’s First Watch (free) AND Evidence does not support the use of gabapentinoids for chronic low back pain – PLOS, via Science Daily (free) AND Gabapentinoids for Chronic Low Back Pain? Not So Fast – Practical Pain Management (free)

Pregabalin and gabapentin have significant risk of adverse effects without any demonstrated benefit in chronic low back pain.

Occupation and Risk of Developing Rheumatoid Arthritis

16 Aug, 2017 | 14:03h | UTC

Occupation and Risk of Developing Rheumatoid Arthritis: Results From a Population-Based Case-Control Study – Arthritis Care & Research (link to abstract – $ for full-text)

Commentaries: Certain occupations linked to an increased risk of rheumatoid arthritis – Willey, via EurekAlert (free) AND Occupational Exposures Increase Rheumatoid Arthritis Risk – Medscape (free registration required) AND Some jobs tied to higher risk of rheumatoid arthritis – Reuters (free)

Case-control study suggests bricklayers, concrete workers, electricians and nurses are at increased risk.

Ibuprofen versus placebo effect on acute kidney injury in ultramarathons

15 Aug, 2017 | 16:09h | UTC

Ibuprofen versus placebo effect on acute kidney injury in ultramarathons: a randomised controlled trial – Emergency Medicine Journal (link to abstract – $ for full-text)

Commentaries: Ibuprofen linked to slight risk of kidney damage in ultramarathoners – Reuters (free) AND Study reveals harmful effects on kidney of Ibuprofen – Stanford Daily (free)

Advances in the diagnosis and management of neck pain

15 Aug, 2017 | 00:33h | UTC

State of the Art Review: Advances in the diagnosis and management of neck pain – The BMJ (free)

Review: My Treatment Approach to Gout

11 Aug, 2017 | 15:54h | UTC

Review: My Treatment Approach to Gout – Mayo Clinic Proceedings (free)

Gout: An old disease in new perspective

11 Aug, 2017 | 12:45h | UTC

Review: Gout: An old disease in new perspective – Journal of Advanced Research (free)

Epidemiology, pathophysiology, and management of uric acid urolithiasis

11 Aug, 2017 | 12:41h | UTC

Review: Epidemiology, pathophysiology, and management of uric acid urolithiasis: A narrative review – Journal of Advanced Research (free)

Nephrolithiasis more common in patients with gout

10 Aug, 2017 | 22:32h | UTC

Incidence of and risk factors for nephrolithiasis in patients with gout and the general population, a cohort study – Arthritis Research & Therapy (free)

Commentaries: Gout Patients Run Higher Risk of Kidney Stones – MedPage Today (free registration required) AND Gout associated with elevated risk for kidney stones – MedWire News (free)

“60% increased risk of first-time nephrolithiasis versus general population, with little protection from allopurinol” (from MedPage Today)

Functional Gain and Pain Relief After Total Joint Replacement According to Obesity Status

10 Aug, 2017 | 19:27h | UTC

Functional Gain and Pain Relief After Total Joint Replacement According to Obesity Status – The Journal of Bone & Joint Surgery (link to abstract – $ for full-text)

Commentaries: Joint Replacement Weight Loss Requirements Challenged – Medscape (free registration required) AND Pain relief, functional outcomes after joint replacement similar in obese and normal-weight patients – News Medical (free)

“Mainstream medicine has failed people with chronic back pain”

Trial of Tocilizumab in Giant-Cell Arteritis

3 Aug, 2017 | 21:39h | UTC

Trial of Tocilizumab in Giant-Cell Arteritis – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: The GiACTA Trial (free)

Commentaries: Tocilizumab improves remission rates in giant-cell arteritis: The GiACTA trial – 2 Minute Medicine (free) AND Phase 3 trial confirms superiority of tocilizumab to steroids for giant cell arteritis – Massachusetts General Hospital, via EurekAlert (free) AND Tocilizumab With Steroid Taper Superior in GCA – Medscape (free registration required)

Are high heels bad for your health?

3 Aug, 2017 | 21:17h | UTC

The 2016 HIGh Heels: Health effects And psychosexual BenefITS (HIGH HABITS) study: systematic review of reviews and additional primary studies – BMC Public Health (free)

Commentary: Are high heels bad for your health? Two experts review the evidence – The Conversation (free)

Atypical fracture with long-term bisphosphonate therapy is associated with altered cortical composition and reduced fracture resistance

3 Aug, 2017 | 20:55h | UTC

Atypical fracture with long-term bisphosphonate therapy is associated with altered cortical composition and reduced fracture resistance – Proceedings of the National Academy of Sciences (free)

Commentaries: Long-Term Bisphosphonate Use Degrades Cortical Bone – Medscape (free registration required) AND How Do Bisphosphonates Cause Atypical Femoral Fractures? – MedPage Today (free registration required) AND Study highlights underlying mechanisms of fractures associated with osteoporosis drug – Cornell University, via EurekAlert (free)

Neck Pain: Updated Clinical Practice Guideline

3 Aug, 2017 | 13:59h | UTC

Neck Pain: Revision 2017 – Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability and Health from the Orthopaedic Section of the American Physical Therapy Association (free)

Effectiveness of oral glucosamine for knee and hip osteoarthritis

3 Aug, 2017 | 14:03h | UTC

Subgroup analyses of the effectiveness of oral glucosamine for knee and hip osteoarthritis: a systematic review and individual patient data meta-analysis from the OA trail bank – Annals of Rheumatic Diseases (link to abstract – $ for full-text) (RT @PhysioMeScience see Tweet)

“Currently, there is no good evidence to support the use of glucosamine for hip or knee OA”