Rheumatology
RCT | Opioids not more effective than placebo for acute low back and neck pain
5 Jul, 2023 | 01:15h | UTCOpioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial – The Lancet (link to abstract – $ for full-text)
News Releases:
Opioids no more effective than placebo for acute back and neck pain – University of Sidney
Opioid pain relievers do not reduce acute lower back and neck pain, study suggests – The Lancet
Commentary from the authors: Opioids don’t relieve acute low back or neck pain – and can result in worse pain, new study finds – The Conversation
Consensus Statement | Evaluation and management of deficiency of adenosine deaminase 2
30 Jun, 2023 | 14:53h | UTCInvited Commentary: Finding a Quorum in Deficiency of Adenosine Deaminase 2 Management – JAMA Network Open
Podcast | Wisely ordering autoantibodies
28 Jun, 2023 | 13:09h | UTC#399 Wisely Ordering Autoantibodies – ACP IM2023 – The Curbsiders
EULAR points to consider for the definition of clinical and imaging features suspicious for progression from psoriasis to psoriatic arthritis
27 Jun, 2023 | 13:37h | UTC
Commentary on Twitter
Have you checked the latest recommendations? @eular_org points to consider for the definition of clinical and imaging features suspicious for progression from PsO to PsA
▶️ 3 stages relevant to PsA prevention
▶️ 5 OP and 10 points to consider🔗 https://t.co/Kr9akTjNC6 pic.twitter.com/cHsg0ZTlb6
— Annals of the Rheumatic Diseases (@eular_ARD) June 21, 2023
RCT | Rituximab and MMF combo improves lung function vs. MMF in interstitial lung disease with NSIP pattern, but may increase infection risk
21 Jun, 2023 | 13:16h | UTCRituximab and mycophenolate mofetil combination in patients with interstitial lung disease (EVER-ILD): a double-blind, randomised, placebo-controlled trial – European Respiratory Journal (link to abstract – $ for full-text)
Commentary on Twitter
ERJ: Rituximab plus MMF is associated with benefits in lung function and progression-free survival compared with MMF plus placebo after 24 weeks of treatment. The safety profile of rituximab plus MMF was similar to that of MMF plus placebo. https://t.co/Mv0IuzLljz pic.twitter.com/1igrt6uDK4
— ERS publications (@ERSpublications) June 11, 2023
M-A | Biosimilar and reference biologics in rheumatoid arthritis show equivalent results
15 Jun, 2023 | 14:47h | UTCCommentary: Adalimumab, Etanercept, Infliximab Biosimilars Show Clinically Equivalence to Biologics in RA – HCP Live
Review | The cervical spine in tension type headache
13 Jun, 2023 | 13:58h | UTCThe cervical spine in tension type headache – Musculoskeletal Science and Practice
Commentary on Twitter
The cervical spine in tension type headache
🤕🤕🤕https://t.co/EFcxBlDO34 pic.twitter.com/y7SyA3T7qt
— Physio Meets Science (@PhysioMeScience) June 1, 2023
Cohort Study | Prognostic model for predicting methotrexate toxicity in immune mediated inflammatory diseases
12 Jun, 2023 | 13:26h | UTCNews Release: New study reveals way to predict side-effect risk from common immune suppressant medication – University of Nottingham
Commentary: Prognostic model stratifies risk for methotrexate toxicity – ACP Internist
Exploratory Analysis of a RCT | Low-dose colchicine linked to reduced incidence of knee and hip replacements
7 Jun, 2023 | 13:50h | UTCAssociation of Low-Dose Colchicine With Incidence of Knee and Hip Replacements: Exploratory Analyses From a Randomized, Controlled, Double-Blind Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
News Release: Low dose colchicine associated with lower incidence of total knee and hip replacements – American College of Physicians
Review | Erythrocyte sedimentation rate and C-reactive protein in the ED
7 Jun, 2023 | 13:47h | UTCErythrocyte Sedimentation Rate and C-Reactive Protein in the ED – emDocs
Systematic Review | Impact of physical therapies on pain, function, and life quality in myofascial pain syndrome
6 Jun, 2023 | 14:07h | UTC
M-A | Efficacy and safety of duloxetine in chronic musculoskeletal pain
5 Jun, 2023 | 13:09h | UTC
Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050
2 Jun, 2023 | 12:34h | UTCEditorial: The global epidemic of low back pain – The Lancet Rheumatology
News Releases:
Commentary on Twitter
NEW—GBD 2021 data published in @TheLancetRheum finds low back pain is the leading cause of disability globally. #LowBackPain affects 619 million individuals (1 out of every 13 people). More women across all age groups suffered from low back pain than men.https://t.co/A2RoU9hn9p pic.twitter.com/vhXwcVh1e7
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) May 22, 2023
ACR Guideline for exercise, rehabilitation, diet, and additional integrative interventions for rheumatoid arthritis
2 Jun, 2023 | 12:33h | UTCNews Release: New Guideline Introduces Recommendations for Integrative Approach to RA Treatment – American College of Rheumatology
Consensus Document | Diagnosis and treatment of lupus nephritis
2 Jun, 2023 | 12:26h | UTC
Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care
2 Jun, 2023 | 12:18h | UTC
SR | Biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome
1 Jun, 2023 | 12:06h | UTC
Proposing a new five-type classification for glomerulonephritis based on pathogenesis, activity, and chronicity
31 May, 2023 | 14:11h | UTC
Commentary on Twitter
The five types of glomerulonephritis classified by pathogenesis, activity & chronicity (GN-AC)
🔓https://t.co/NYKBde4L1I
📸The major entities of GN
📸Autoantigens in autoimmune GN
📸Multilevel diagnostic algorithm of GN
📸Proposed GN-AC classification & reporting system for GN pic.twitter.com/shmLLhCfJk— NDT (@NDTsocial) May 24, 2023
Guideline for the diagnosis and management of eosinophilic granulomatosis with polyangiitis
24 May, 2023 | 13:16h | UTCEvidence-Based Guideline for the diagnosis and management of eosinophilic granulomatosis with polyangiitis – Nature Reviews Rheumatology (if the link is paywalled, try this one)
Related: 2022 ACR/EULAR Classification Criteria for Eosinophilic Granulomatosis with Polyangiitis.
Commentary on Twitter
New content online! Evidence-Based Guideline for the diagnosis and management of eosinophilic granulomatosis with polyangiitis https://t.co/iBNSi55JfK pic.twitter.com/Wh71oHGXOL
— NatRevRheumatol (@NatRevRheumatol) May 9, 2023
Review | Update in musculoskeletal pain in older adults with a focus on osteoarthritis-related pain
24 May, 2023 | 13:09h | UTC
Phase 2 RCT | Peresolimab outperforms placebo in patients with moderate-to-severe rheumatoid arthritis
24 May, 2023 | 13:07h | UTCA Phase 2 Trial of Peresolimab for Adults with Rheumatoid Arthritis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Peresolimab Demonstrates Efficacy in Treating Patients With Rheumatoid Arthritis – HCP Live
Commentary on Twitter
Peresolimab showed efficacy in a phase 2a trial in patients with rheumatoid arthritis. These results provide evidence that stimulation of the PD-1 receptor has potential efficacy in the treatment of rheumatoid arthritis. https://t.co/2MkxLBrKTf
— NEJM (@NEJM) May 20, 2023
M-A | Limited evidence for safety and effectiveness of most antidepressants in chronic pain management
18 May, 2023 | 13:50h | UTC
Cohort Study | Patients with joint hypermobility at greater risk of second ACL injury post-surgery within a year of return to sport
18 May, 2023 | 13:33h | UTCRCT | Colchicine ineffective for pain relief in hand osteoarthritis patients
16 May, 2023 | 14:42h | UTCColchicine twice a day for hand osteoarthritis (COLOR): a double-blind, randomised, placebo-controlled trial – The Lancet Rheumatology (link to abstract – $ for full-text)
Commentary: Colchicine Does Not Relieve OA-Related Hand Pain Compared With Placebo – DocWireNews
Commentary on Twitter
NEW RESEARCH—@AnnaDossing and colleagues report the results of the COLOR trial; #colchicine twice a day did not relieve #pain vs placebo in people with hand #osteoarthritis https://t.co/LfKTwVONGM pic.twitter.com/jTBh076LZ6
— The Lancet Rheumatology (@TheLancetRheum) April 5, 2023
Canadian Task Force advises fragility fracture screening for women over 65, but not for men or younger women
15 May, 2023 | 13:23h | UTCRelated USPSTF Statement: Screening Osteoporosis to Prevent Fractures