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Rheumatology

RCT | Opioids not more effective than placebo for acute low back and neck pain

5 Jul, 2023 | 01:15h | UTC

Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

News Releases:

Opioids no more effective than placebo for acute back and neck pain – University of Sidney

Opioid pain relievers do not reduce acute lower back and neck pain, study suggests – The Lancet

Commentary from the authors: Opioids don’t relieve acute low back or neck pain – and can result in worse pain, new study finds – The Conversation

 


Consensus Statement | Evaluation and management of deficiency of adenosine deaminase 2

30 Jun, 2023 | 14:53h | UTC

Evaluation and Management of Deficiency of Adenosine Deaminase 2: An International Consensus Statement – JAMA Network Open

Invited Commentary: Finding a Quorum in Deficiency of Adenosine Deaminase 2 Management – JAMA Network Open

 


Podcast | Wisely ordering autoantibodies

28 Jun, 2023 | 13:09h | UTC

#399 Wisely Ordering Autoantibodies – ACP IM2023 – The Curbsiders

 


EULAR points to consider for the definition of clinical and imaging features suspicious for progression from psoriasis to psoriatic arthritis

27 Jun, 2023 | 13:37h | UTC

EULAR points to consider for the definition of clinical and imaging features suspicious for progression from psoriasis to psoriatic arthritis – Annals of the Rheumatic Diseases

 

Commentary on Twitter

 


RCT | Rituximab and MMF combo improves lung function vs. MMF in interstitial lung disease with NSIP pattern, but may increase infection risk

21 Jun, 2023 | 13:16h | UTC

Rituximab and mycophenolate mofetil combination in patients with interstitial lung disease (EVER-ILD): a double-blind, randomised, placebo-controlled trial – European Respiratory Journal (link to abstract – $ for full-text)

 

Commentary on Twitter

 


M-A | Biosimilar and reference biologics in rheumatoid arthritis show equivalent results

15 Jun, 2023 | 14:47h | UTC

Therapeutic Equivalence of Biosimilar and Reference Biologic Drugs in Rheumatoid Arthritis: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary: Adalimumab, Etanercept, Infliximab Biosimilars Show Clinically Equivalence to Biologics in RA – HCP Live

 


Review | The cervical spine in tension type headache

13 Jun, 2023 | 13:58h | UTC

The cervical spine in tension type headache – Musculoskeletal Science and Practice

 

Commentary on Twitter

 


Cohort Study | Prognostic model for predicting methotrexate toxicity in immune mediated inflammatory diseases

12 Jun, 2023 | 13:26h | UTC

Risk stratified monitoring for methotrexate toxicity in immune mediated inflammatory diseases: prognostic model development and validation using primary care data from the UK – The BMJ

News Release: New study reveals way to predict side-effect risk from common immune suppressant medication – University of Nottingham

Commentary: Prognostic model stratifies risk for methotrexate toxicity – ACP Internist

 


Exploratory Analysis of a RCT | Low-dose colchicine linked to reduced incidence of knee and hip replacements

7 Jun, 2023 | 13:50h | UTC

Association of Low-Dose Colchicine With Incidence of Knee and Hip Replacements: Exploratory Analyses From a Randomized, Controlled, Double-Blind Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Low dose colchicine associated with lower incidence of total knee and hip replacements – American College of Physicians

Commentary: Colchicine linked to lower incidence of total knee, hip replacements in patients with chronic coronary artery disease – ACP Internist

 


Review | Erythrocyte sedimentation rate and C-reactive protein in the ED

7 Jun, 2023 | 13:47h | UTC

Erythrocyte Sedimentation Rate and C-Reactive Protein in the ED – emDocs

 


Systematic Review | Impact of physical therapies on pain, function, and life quality in myofascial pain syndrome

6 Jun, 2023 | 14:07h | UTC

The effect of therapeutic physical modalities on pain, function, and quality of life in patients with myofascial pain syndrome: a systematic review – BMC Musculoskeletal Disorders

 


M-A | Efficacy and safety of duloxetine in chronic musculoskeletal pain

5 Jun, 2023 | 13:09h | UTC

Efficacy and safety of duloxetine in chronic musculoskeletal pain: a systematic review and meta-analysis – BMC Musculoskeletal Disorders

 


Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050

2 Jun, 2023 | 12:34h | UTC

Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021 – The Lancet Rheumatology

Editorial: The global epidemic of low back pain – The Lancet Rheumatology

News Releases:

New study shows low back pain is the leading cause of disability around the world – Institute for Health Metrics and Evaluation

In 2050, over 800 million people globally estimated to be living with back pain – The University of Sidney

 

Commentary on Twitter

 


ACR Guideline for exercise, rehabilitation, diet, and additional integrative interventions for rheumatoid arthritis

2 Jun, 2023 | 12:33h | UTC

2022 American College of Rheumatology Guideline for Exercise, Rehabilitation, Diet, and Additional Integrative Interventions for Rheumatoid Arthritis – Arthritis Care & Research

Editorial: Patient Perspectives on the 2022 American College of Rheumatology Guideline for Exercise, Rehabilitation, Diet, and Additional Integrative Interventions for Rheumatoid Arthritis – Arthritis Care & Research

News Release: New Guideline Introduces Recommendations for Integrative Approach to RA Treatment – American College of Rheumatology

 


Consensus Document | Diagnosis and treatment of lupus nephritis

2 Jun, 2023 | 12:26h | UTC

Consensus document of the Spanish Group for the Study of the Glomerular Diseases (GLOSEN) for the diagnosis and treatment of lupus nephritis – Nefrología

 


Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care

2 Jun, 2023 | 12:18h | UTC

Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care – Nature Reviews Rheumatology

 


SR | Biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome

1 Jun, 2023 | 12:06h | UTC

Biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a systematic review – BMC Medicine

 


Proposing a new five-type classification for glomerulonephritis based on pathogenesis, activity, and chronicity

31 May, 2023 | 14:11h | UTC

The five types of glomerulonephritis classified by pathogenesis, activity, and chronicity (GN-AC) – Nephrology Dialysis Transplantation

 

Commentary on Twitter

 


Guideline for the diagnosis and management of eosinophilic granulomatosis with polyangiitis

24 May, 2023 | 13:16h | UTC

Evidence-Based Guideline for the diagnosis and management of eosinophilic granulomatosis with polyangiitis – Nature Reviews Rheumatology (if the link is paywalled, try this one)

Related: 2022 ACR/EULAR Classification Criteria for Eosinophilic Granulomatosis with Polyangiitis.

 

Commentary on Twitter

 


Review | Update in musculoskeletal pain in older adults with a focus on osteoarthritis-related pain

24 May, 2023 | 13:09h | UTC

Clin-STAR corner: 2021 update in musculoskeletal pain in older adults with a focus on osteoarthritis-related pain – Journal of the American Geriatrics Society

 


Phase 2 RCT | Peresolimab outperforms placebo in patients with moderate-to-severe rheumatoid arthritis

24 May, 2023 | 13:07h | UTC

A Phase 2 Trial of Peresolimab for Adults with Rheumatoid Arthritis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Peresolimab Demonstrates Efficacy in Treating Patients With Rheumatoid Arthritis – HCP Live

 

Commentary on Twitter

 


M-A | Limited evidence for safety and effectiveness of most antidepressants in chronic pain management

18 May, 2023 | 13:50h | UTC

Antidepressants for pain management in adults with chronic pain: a network meta‐analysis – Cochrane Library

News Release: Most antidepressants prescribed for chronic pain lack reliable evidence of efficacy or safety, scientists warn – Cochrane Library

Summary: How effective are antidepressants used to treat chronic pain and do they cause unwanted effects? – Cochrane Library

Commentary: Expert reaction to Cochrane review on antidepressants for pain management in adults with chronic pain – Science Media Centre

 


Cohort Study | Patients with joint hypermobility at greater risk of second ACL injury post-surgery within a year of return to sport

18 May, 2023 | 13:33h | UTC

Generalised joint hypermobility leads to increased odds of sustaining a second ACL injury within 12 months of return to sport after ACL reconstruction – British Journal of Sports Medicine


RCT | Colchicine ineffective for pain relief in hand osteoarthritis patients

16 May, 2023 | 14:42h | UTC

Colchicine twice a day for hand osteoarthritis (COLOR): a double-blind, randomised, placebo-controlled trial – The Lancet Rheumatology (link to abstract – $ for full-text)

Commentary: Colchicine Does Not Relieve OA-Related Hand Pain Compared With Placebo – DocWireNews

 

Commentary on Twitter

 


Canadian Task Force advises fragility fracture screening for women over 65, but not for men or younger women

15 May, 2023 | 13:23h | UTC

Recommendations on screening for primary prevention of fragility fractures – Canadian Medical Association Journal

Related USPSTF Statement: Screening Osteoporosis to Prevent Fractures

 


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