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Systematic Reviews & Meta-analysis

Systematic Review: Negative Pressure Wound Therapy for Surgical Wounds Healing by Primary Closure

5 May, 2020 | 03:33h | UTC

Negative pressure wound therapy for surgical wounds healing by primary closure – Cochrane Library

Summary: Negative pressure wound therapy for surgical wounds healing by primary closure – Cochrane Library

 


Systematic Review: No Evidence to Support the Use of Aspirin for the Prevention of Dementia

1 May, 2020 | 02:38h | UTC

Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia – Cochrane Library

Summary: Aspirin and other non-steroidal anti-inflammatory drugs for the prevention of dementia – Cochrane Library

Related Randomized Trial: Aspirin Not Beneficial for Reducing the Risk of Dementia, MCI, or Cognitive Decline

 


Systematic Review: Treating Disseminated Histoplasmosis in People Living with HIV

30 Apr, 2020 | 03:41h | UTC

Treating progressive disseminated histoplasmosis in people living with HIV – Cochrane Library

Summary: How best to treat progressive disseminated histoplasmosis in people with HIV – Cochrane Library

 


Systematic Review: Antidepressants for Smoking Cessation

29 Apr, 2020 | 04:40h | UTC

Antidepressants for smoking cessation – Cochrane Library

Summary: Do medicines used to treat depression help people to quit smoking? – Cochrane Library

 


Systematic Review: Vaginal Preparation with Antiseptic Solution Before Cesarean Section for Preventing Postoperative Infections

29 Apr, 2020 | 04:36h | UTC

Vaginal preparation with antiseptic solution before cesarean section for preventing postoperative infections – Cochrane Library

 


Systematic Review: SARS-CoV-2 Infection in Children and Adolescents

23 Apr, 2020 | 09:40h | UTC

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents: A Systematic Review – JAMA Pediatrics

Commentaries: Most kids with coronavirus usually recover within two weeks, JAMA study finds – CNBC AND Young people at lower risk for COVID-19, can still transmit the virus – UPI AND Expert reaction to systematic review of COVID-19 in children – Science Media Centre

 


Meta-Analysis: Interventions for the Management of Malignant Pleural Effusions

23 Apr, 2020 | 09:22h | UTC

Interventions for the management of malignant pleural effusions: a network meta‐analysis – Cochrane Library

 


Cochrane Review Confirms Effectiveness and Safety of MMR vaccines

23 Apr, 2020 | 09:24h | UTC

Vaccines for measles, mumps, rubella, and varicella in children – Cochrane Library

News Release: Cochrane Review confirms effectiveness of MMR vaccines – Cochrane Library

 


Systematic Review: Prophylactic Role of Chloroquine and Hydroxychloroquine in COVID‐19

19 Apr, 2020 | 23:57h | UTC

A systematic review of the prophylactic role of chloroquine and hydroxychloroquine in Coronavirus Disease‐19 (COVID‐19) – International Journal of Rheumatic Diseases

Commentary: ‘Dearth of evidence’ to support prophylactic chloroquine, hydroxychloroquine use for COVID-19 – Medicine Matters

 


Meta-Analysis: Hematologic, Biochemical and Immune Biomarker Abnormalities Associated with Severe Illness and Mortality in COVID-19

17 Apr, 2020 | 02:22h | UTC

Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis – Clinical Chemistry and Laboratory Medicine

“non-survivors compared to survivors had more significant increases in WBC count, total bilirubin, creatine kinase, serum ferritin, and interleukin 6 (IL-6), and more significant decreases in lymphocyte count and platelet count.”

 


Meta-Analysis: Aspirin and the Risk of Colorectal and Other Digestive Tract Cancers

17 Apr, 2020 | 01:54h | UTC

Aspirin and the risk of colorectal and other digestive tract cancers: an updated meta-analysis through 2019 – Annals of Oncology

News Release: Aspirin linked to reduction in risk of several cancers of the digestive tract – European Society of Medical Oncology

 


Face Masks Against COVID-19: An Evidence Review

14 Apr, 2020 | 02:52h | UTC

Face Masks Against COVID-19: An Evidence Review – Preprints

Related Analysis: Face Masks for the Public During the Covid-19 Crisis

 


Systematic Review: Maternal and Perinatal Outcomes with COVID‐19

14 Apr, 2020 | 02:41h | UTC

Maternal and Perinatal Outcomes with COVID‐19: a systematic review of 108 pregnancies – Acta Obstetricia et Gynecologica Scandinavica

 


Systematic Review: How Effective is Quarantine to Control Coronavirus (COVID-19)?

9 Apr, 2020 | 03:50h | UTC

Quarantine alone or in combination with other public health measures to control COVID‐19: a rapid review – Cochrane Library

Commentary: How effective is quarantine alone or in combination with other public health measures to control coronavirus (COVID-19)? – Cochrane Library

 


Systematic Review: Prediction Models for Diagnosis and Prognosis of Covid-19

8 Apr, 2020 | 01:29h | UTC

Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal – The BMJ

Commentary: Expert reaction to a systematic review of prediction models for diagnosis and prognosis of COVID-19 infection – Science Media Centre

 

Related Commentary on Twitter

 


Meta-Analysis: Comparative Weight Loss with Popular Diets

3 Apr, 2020 | 03:50h | UTC

Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials – The BMJ

Editorial: Comparative weight loss with popular diets

Commentary: Most Diets Lead to Weight Loss and Lower Blood Pressure, but Effects Largely Disappear After a Year: Study – MDIndia

 


Systematic Review: Causes of the Transmission and Control Measures of Outbreaks in Long-term Care Facilities

13 Mar, 2020 | 07:55h | UTC

A systematic review on the causes of the transmission and control measures of outbreaks in long-term care facilities: Back to basics of infection control – PLOS One (free)

 


Meta-Analysis of Randomized Trials: Little Benefit from Omega-3 Intake to Reduce Cardiovascular Disease Risk

13 Mar, 2020 | 07:52h | UTC

Omega‐3 fatty acids for the primary and secondary prevention of cardiovascular disease – Cochrane Library (free)

Summary: Omega-3 intake for cardiovascular disease – Cochrane Library (free)

Author Interview: Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease – Cochrane Library (free)

Commentary: Omega-3s Show No Overall Benefits for Heart Health or Cancer Prevention – The New York Times (free)

 


[Abstract Only] Meta-analysis of Randomized trials: Omega-3 Fats do not Protect Against Cancer

13 Mar, 2020 | 07:51h | UTC

Omega-3, omega-6 and total dietary polyunsaturated fat on cancer incidence: systematic review and meta-analysis of randomised trials – British Journal of Cancer (link to abstract – $ for full-text)

Commentary: Omega-3 fats do not protect against cancer – University of East Anglia (free)

 


Systematic Review: Alcoholics Anonymous Very Effective for Alcohol Use Disorder

12 Mar, 2020 | 08:10h | UTC

Alcoholics Anonymous and other 12‐step programs for alcohol use disorder – Cochrane Library (free)

Author Interview: Alcoholics Anonymous and other 12-step programs for alcohol use disorder (free)

News Release: New Cochrane Review finds Alcoholics Anonymous and 12-Step Facilitation programs help people to recover from alcohol problems (free)

Commentaries: A new, big review of the evidence found that Alcoholics Anonymous works — for some – Vox (free) AND Alcoholics Anonymous validated by meta-analysis: ‘It absolutely does work’ – Stanford Medicine (free)

 


Meta-Analysis: T-piece vs. Pressure Support Ventilation as Spontaneous Breathing Trials in Critically Ill Patients

8 Mar, 2020 | 20:43h | UTC

Comparison of T-piece and pressure support ventilation as spontaneous breathing trials in critically ill patients: a systematic review and meta-analysis – Critical Care (free)

 

Related Commentary on Twitter

 


Meta-Analysis: Watchful Waiting Strategy vs. Early Initiation of Renal Replacement Therapy in Critically Ill Patients with Acute Kidney Injury

5 Mar, 2020 | 10:25h | UTC

Comparison between watchful waiting strategy and early initiation of renal replacement therapy in the critically ill acute kidney injury population: an updated systematic review and meta-analysis – Annals of Intensive Care (free)

Related: Review: Renal Replacement Therapy in the Critical Care Setting (free resources)

 


Meta-Analysis: Incidence of Maternal Peripartum Infection

4 Mar, 2020 | 08:22h | UTC

Incidence of maternal peripartum infection: A systematic review and meta-analysis – PLOS Medicine (free)

 


Meta-Analysis: Melatonin Shows Potential for Reducing Delirium Among Older People after Surgery

4 Mar, 2020 | 08:20h | UTC

Melatonin shows potential for reducing delirium among older people after surgery – NIHR Signal (free)

Original Study: Melatonin for the prevention of postoperative delirium in older adults: a systematic review and meta-analysis – BMC Geriatrics (free)

 


Study: People Leave Hospital After Surgery Sooner if Hospitals Follow ‘Enhanced Recovery Protocols’

3 Mar, 2020 | 07:55h | UTC

People leave hospital after surgery sooner if hospitals follow ‘enhanced recovery protocols’ – NIHR Signal (free)

Original Study: Multicomponent hospital-led interventions to reduce hospital stay for older adults following elective surgery: a systematic review – Health Services and Delivery Research (free)

 


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