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Systematic Reviews & Meta-analysis

M-A | The outcome of post-cardiotomy extracorporeal membrane oxygenation in neonates and pediatric patients.

4 Aug, 2022 | 13:48h | UTC

The Outcome of Post-cardiotomy Extracorporeal Membrane Oxygenation in Neonates and Pediatric Patients: A Systematic Review and Meta-Analysis – Frontiers in Pediatrics

 


M-A | Repeat hepatic resection vs. percutaneous ablation for the treatment of recurrent hepatocellular carcinoma.

4 Aug, 2022 | 13:27h | UTC

Repeat hepatic resection versus percutaneous ablation for the treatment of recurrent hepatocellular carcinoma: meta-analysis – BJS Open

 

Commentary on Twitter

 


M-A | Response to acute monotherapy for major depressive disorder in randomized, placebo controlled trials.

3 Aug, 2022 | 14:31h | UTC

Response to acute monotherapy for major depressive disorder in randomized, placebo controlled trials submitted to the US Food and Drug Administration: individual participant data analysis – The BMJ

 


M-A | GLP1 receptor agonists are associated with increased risk of progression of retinopathy in patients with type 2 diabetes.

2 Aug, 2022 | 12:32h | UTC

Progression of retinopathy with glucagon-like peptide-1 receptor agonists with cardiovascular benefits in type 2 diabetes – A systematic review and meta-analysis – Journal of Diabetes and its Complications (link to abstract – $ for full-text)

Commentary: GLP1 RA use tied to increased risk of rapidly worsening retinopathy in type 2 diabetes – Medical Dialogues

 


M-A | Perioperative care bundles for the prevention of surgical-site infections.

2 Aug, 2022 | 12:30h | UTC

Perioperative care bundles for the prevention of surgical-site infections: meta-analysis – British Journal of Surgery

 


Systematic Review | Physical activity for treatment of irritable bowel syndrome.

2 Aug, 2022 | 12:12h | UTC

Physical activity for treatment of irritable bowel syndrome – Cochrane Library

Summary: What are the benefits and harms of physical activity for people with irritable bowel syndrome – Cochrane Library

 


M-A | The prevalence and incidence of NAFLD worldwide.

2 Aug, 2022 | 11:34h | UTC

The prevalence and incidence of NAFLD worldwide: a systematic review and meta-analysis – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: NAFLD Incidence, Prevalence Increasing Worldwide – HCPLive

 

Commentary on Twitter

 


M-A | Probiotics in critical illness.

1 Aug, 2022 | 12:28h | UTC

Probiotics in Critical Illness: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Critical Care Medicine (free for a limited period)

 

Commentary on Twitter

 


M-A | Respiratory support strategy in adults with acute hypoxemic respiratory failure.

1 Aug, 2022 | 12:18h | UTC

Respiratory support strategy in adults with acute hypoxemic respiratory failure: a systematic review and network meta-analysis – JA Clinical Reports

 


M-A | Prevalence of suicidal ideation and self-harm behaviors in children aged 12 years and younger.

1 Aug, 2022 | 12:01h | UTC

Prevalence of suicidal ideation and self-harm behaviours in children aged 12 years and younger: a systematic review and meta-analysis – The Lancet Psychiatry (link to abstract – $ for full-text)

 

Commentary on Twitter

 


M-A | Cardiovascular and venous thromboembolic risk with Janus Kinase inhibitors in immune-mediated inflammatory diseases.

1 Aug, 2022 | 11:52h | UTC

Cardiovascular and Venous Thromboembolic Risk With Janus Kinase Inhibitors in Immune-Mediated Inflammatory Diseases: A Systematic Review and Meta-Analysis of Randomized Trials – ACR Open Rheumatology

 


M-A | Endoscopic resection versus surgery in the treatment of early gastric cancer.

1 Aug, 2022 | 11:56h | UTC

Endoscopic Resection Versus Surgery in the Treatment of Early Gastric Cancer: A Systematic Review and Meta-Analysis – Frontiers in Oncology

 


Network M-A | Efficacy of biological therapies and small molecules in induction and maintenance of remission in luminal Crohn’s disease.

1 Aug, 2022 | 11:45h | UTC

Efficacy of biological therapies and small molecules in induction and maintenance of remission in luminal Crohn’s disease: systematic review and network meta-analysis – Gut (link to abstract – $ for full-text)

 


Systematic Review | Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection.

29 Jul, 2022 | 12:39h | UTC

Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection – Cochrane Library

Summary: How accurate are rapid antigen tests for diagnosing COVID-19? – Cochrane Library

 


Systematic Review | Antiplatelet agents and anticoagulants for hypertension.

29 Jul, 2022 | 12:29h | UTC

Antiplatelet agents and anticoagulants for hypertension – Cochrane Library

Summary: Antiplatelet agents and anticoagulants for high blood pressure – Cochrane Library

 

Commentary on Twitter

 


M-A | Lung cancer occurrence after an episode of tuberculosis.

29 Jul, 2022 | 12:28h | UTC

Lung cancer occurrence after an episode of tuberculosis: a systematic review and meta-analysis – European Respiratory Review

 


M-A | Socioeconomic indicators of treatment prognosis for adults with depression.

29 Jul, 2022 | 12:17h | UTC

Socioeconomic Indicators of Treatment Prognosis for Adults With Depression: A Systematic Review and Individual Patient Data Meta-analysis – JAMA Psychiatry

News Release: People without jobs or secure housing have worse outcomes when treated for depression – University College London

Commentary: Unemployment and insecure housing are linked to less successful treatment for depression – National Institute for Health and Care Research

 

Commentary on Twitter

 


M-A | Nonoperative vs. operative management of uncomplicated acute appendicitis.

28 Jul, 2022 | 13:30h | UTC

Nonoperative vs Operative Management of Uncomplicated Acute Appendicitis: A Systematic Review and Meta-Analysis – JAMA Surgery (free for a limited period)

Related:

Efficacy and Safety of Non-Operative Management of Uncomplicated Acute Appendicitis Compared to Appendectomy: An Umbrella Review of Systematic Reviews and Meta-Analyses – World Journal of Surgery

Cohort Study: Patient factors associated with appendectomy within 30 days of initiating antibiotic treatment for appendicitis – the presence of an appendicolith was associated with a nearly 2-fold increased risk of undergoing appendectomy within 30 days.

Review: Diagnosis of uncomplicated and complicated appendicitis in adults.

Another RCT evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis.

A Randomized trial comparing antibiotics with appendectomy for appendicitis

Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin

Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis

Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis

Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children

Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International

 

Commentary on Twitter

 


M-A | Negative-pressure wound therapy for prevention of sternal wound infection after adult cardiac surgery.

28 Jul, 2022 | 13:03h | UTC

Negative-Pressure Wound Therapy for Prevention of Sternal Wound Infection after Adult Cardiac Surgery: Systematic Review and Meta-Analysis – Journal of Clinical Medicine

 


M-A | The efficacy of topical sucralfate in improving pain and wound healing after hemorrhoidectomy procedure.

28 Jul, 2022 | 13:02h | UTC

The efficacy of topical sucralfate in improving pain and wound healing after haemorrhoidectomy procedure: A systematic review, meta-analysis, and meta-regression of randomised clinical trials – International Wound Journal

 


M-A | Treating eosinophilic esophagitis with budesonide.

27 Jul, 2022 | 12:06h | UTC

A meta-analysis on randomized controlled trials of treating eosinophilic esophagitis with budesonide – Annals of Medicine

 


M-A | Comparison of the efficacy and safety of quetiapine and lithium for bipolar depression.

27 Jul, 2022 | 11:55h | UTC

Comparison of the efficacy and safety of quetiapine and lithium for bipolar depression: A systematic review and meta-analysis of randomized controlled trials – Neuropsychopharmacology Reports

 


M-A | Effectiveness of wearable activity trackers to increase physical activity and improve health.

26 Jul, 2022 | 13:27h | UTC

Effectiveness of wearable activity trackers to increase physical activity and improve health: a systematic review of systematic reviews and meta-analyses – The Lancet Digital Health

Commentary: Wearable activity trackers encourage us to walk up to 40 minutes more each day – University of South Australia

 

Commentary on Twitter

Under a CC BY-NC-ND 4.0 license

 


Systematic Review | Antiplatelet agents for the treatment of deep venous thrombosis.

26 Jul, 2022 | 12:44h | UTC

Antiplatelet agents for the treatment of deep venous thrombosis – Cochrane Library

Summary: Aspirin and similar drugs for the treatment of deep vein thrombosis (DVT) – Cochrane Library

 


Central venous catheter (CVC) management: evidence round-up.

26 Jul, 2022 | 12:41h | UTC

Central venous catheter (CVC) management: evidence round-up – Cochrane Library

Related: Heparin versus 0.9% sodium chloride locking for prevention of occlusion in central venous catheters in adults – Cochrane Library

Summary: Does heparin locking prevent blocking of central venous catheters in adults when compared to locking with normal saline? – Cochrane Library

 


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