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Systematic Reviews & Meta-analysis

M-A | Erlotinib plus bevacizumab vs. erlotinib alone in patients with EGFR-positive advanced non-small-cell lung cancer.

22 Aug, 2022 | 12:04h | UTC

Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-small-cell lung cancer: a systematic review and meta-analysis of randomised controlled trials – BMJ Open

 


M-A | Minimally invasive versus open central pancreatectomy.

22 Aug, 2022 | 11:58h | UTC

Minimally invasive versus open central pancreatectomy: Systematic review and meta-analysis – Surgery

 


Calcium for pre-eclampsia prevention | A systematic review and network meta-analysis to guide personalized antenatal care.

22 Aug, 2022 | 11:47h | UTC

Calcium for pre-eclampsia prevention: A systematic review and network meta-analysis to guide personalised antenatal care – British Journal of Obstetrics and Gynaecology

Related: WHO recommendation: Calcium supplementation during pregnancy for the prevention of pre-eclampsia and its complications – World Health Organization

 

Commentary on Twitter

 


M-A | Incidence of neonatal developmental dysplasia of the hip and late detection rates based on screening strategy.

19 Aug, 2022 | 16:07h | UTC

Incidence of Neonatal Developmental Dysplasia of the Hip and Late Detection Rates Based on Screening Strategy: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary: Universal Hip Screening in Babies Associated With Overtreatment — Late detection of hip dysplasia and need for surgery not helped by universal screening – MedPage Today (free registration required)

 

Commentary on Twitter

 


M-A | Efficacy of corticosteroids for hand osteoarthritis.

19 Aug, 2022 | 16:03h | UTC

Efficacy of corticosteroids for hand osteoarthritis – a systematic review and meta-analysis of randomized controlled trials – BMC Musculoskeletal Disorders

 


M-A | Performance of confirmatory tests for diagnosing primary aldosteronism.

18 Aug, 2022 | 12:54h | UTC

Performance of Confirmatory Tests for Diagnosing Primary Aldosteronism: a Systematic Review and Meta-Analysis – Hypertension

 

Commentary on Twitter

https://twitter.com/HyperAHA/status/1559624529869160448

 


M-A | Interventions for the prevention or treatment of epidural-related maternal fever.

18 Aug, 2022 | 12:45h | UTC

Interventions for the prevention or treatment of epidural-related maternal fever: a systematic review and meta-analysis – British Journal of Anaesthesia

 


Treatments for vaginal thrush: a quick look at the evidence.

17 Aug, 2022 | 14:16h | UTC

Original Reviews:

Treatment for recurrent vulvovaginal candidiasis (thrush) – Cochrane Library

Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis (thrush) – Cochrane Library

 


Systematic Review | Menopausal status, ultrasound and biomarker tests in combination for the diagnosis of ovarian cancer in symptomatic women.

17 Aug, 2022 | 14:12h | UTC

Menopausal status, ultrasound and biomarker tests in combination for the diagnosis of ovarian cancer in symptomatic women – Cochrane Library

Summary: What is the accuracy of different combinations of ultrasound imaging and blood tests to diagnose ovarian cancer in women before and after the menopause? – Cochrane Library

 


Talking about dying: better conversations at the end of life.

17 Aug, 2022 | 14:14h | UTC

Talking about dying: better conversations at the end of life – Evidently Cochrane

Original Reviews:

Interventions for interpersonal communication about end of life care between health practitioners and affected people – Cochrane Library

Communicating with patients and families about illness progression and end of life: a review of studies using direct observation of clinical practice – BMC Palliative Care

 

Commentary on Twitter

 


Systematic Review | Accuracy of measures for antiretroviral adherence in people living with HIV.

17 Aug, 2022 | 14:11h | UTC

Accuracy of measures for antiretroviral adherence in people living with HIV – Cochrane Library

Summary: Are there good ways to find out if people living with HIV are taking their medicines every day? – Cochrane Library

 


M-A | Extent of tumor resection and survival in pediatric patients with high-grade gliomas.

17 Aug, 2022 | 14:00h | UTC

Extent of Tumor Resection and Survival in Pediatric Patients With High-Grade Gliomas: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


M-A | Association of anticancer immune checkpoint inhibitors with patient-reported outcomes assessed in randomized clinical trials.

17 Aug, 2022 | 14:02h | UTC

Association of Anticancer Immune Checkpoint Inhibitors With Patient-Reported Outcomes Assessed in Randomized Clinical Trials: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


M-A | The incidence and risk of venous thromboembolism associated with peripherally inserted central venous catheters in hospitalized patients.

17 Aug, 2022 | 13:49h | UTC

The incidence and risk of venous thromboembolism associated with peripherally inserted central venous catheters in hospitalized patients: A systematic review and meta-analysis – Frontiers in Cardiovascular Medicine

 


Network M-A | Comparison of doses and injection sites of botulinum toxin for chronic anal fissure.

17 Aug, 2022 | 13:48h | UTC

Comparison of doses and injection sites of botulinum toxin for chronic anal fissure: A systematic review and network meta-analysis of randomized controlled trials – International Journal of Surgery

 


M-A | Dexmedetomidine versus clonidine as an adjuvant to local anesthetic in brachial plexus blocks.

17 Aug, 2022 | 13:44h | UTC

Dexmedetomidine versus clonidine as an adjuvant to local anaesthetic in brachial plexus blocks: a meta-analysis of randomised controlled trials – Brazilian Journal of Anesthesiology

 


Network M-A | Efficacy and safety of 12 immunosuppressive agents for idiopathic membranous nephropathy in adults.

16 Aug, 2022 | 13:10h | UTC

Efficacy and safety of 12 immunosuppressive agents for idiopathic membranous nephropathy in adults: A pairwise and network meta-analysis – Frontiers in Pharmacology

Related:

Immunosuppressive treatment for primary membranous nephropathy in adults with nephrotic syndrome – Cochrane Library

Treatment of Idiopathic Membranous Nephropathy for Moderate or Severe Proteinuria: A Systematic Review and Network Meta-Analysis – International Journal of Clinical Practice

 


M-A | How effective is indocyanine green in localization of malignant pulmonary nodules?

16 Aug, 2022 | 13:09h | UTC

How effective is indocyanine green (ICG) in localization of malignant pulmonary nodules? A systematic review and meta-analysis – Frontiers in Surgery

 


M-A | Effect of regional anesthesia on postoperative delirium.

16 Aug, 2022 | 13:08h | UTC

Effect of regional anesthesia on the postoperative delirium: A systematic review and meta-analysis of randomized controlled trials – Frontiers in Surgery

 


M-A | Efficacy and safety of unilateral biportal endoscopy versus other spine surgery.

16 Aug, 2022 | 13:06h | UTC

Efficacy and safety of unilateral biportal endoscopy versus other spine surgery: A systematic review and meta-analysis – Frontiers in Surgery

 


M-A | Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course.

15 Aug, 2022 | 12:21h | UTC

Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis – The Lancet Global Health

Invited Commentary: Infant BCG vaccination is beneficial, but not sufficient – The Lancet Global Health

News Release: BCG vaccine prevents tuberculosis in young children, but not adults – Boston University School of Public Health

 

Commentary from the author on Twitter (thread – click for more)

https://twitter.com/LeoMarti_EpiTB/status/1557138585119141889

 


Network M-A | Tocolytics for delaying preterm birth.

15 Aug, 2022 | 12:17h | UTC

Tocolytics for delaying preterm birth: a network meta‐analysis – Cochrane Library

Summary: Are medicines that delay the start of labour (tocolytics) effective for delaying preterm birth? – Cochrane Library

News Release: Preterm birth delay drugs safe for global reduction in neonatal death – University of Birmingham

 


M-A of randomized trials | Prophylactic tranexamic acid to reduce blood loss and related morbidities during hysterectomy.

15 Aug, 2022 | 11:49h | UTC

Prophylactic tranexamic acid to reduce blood loss and related morbidities during hysterectomy: a systematic review and meta-analysis of randomized controlled trials – Obstetrics & Gynecology Science (PDF)

 


Systematic Review | Psychological therapies for temporomandibular disorders.

15 Aug, 2022 | 11:39h | UTC

Psychological therapies for temporomandibular disorders (TMDs) – Cochrane Library

Summary: What are the benefits and risks of psychological therapies for adults and young people over 12 years old with painful temporomandibular disorders (TMDs)? – Cochrane Library

 


M-A | Medications for the treatment of pulmonary arterial hypertension.

12 Aug, 2022 | 14:32h | UTC

Medications for the treatment of pulmonary arterial hypertension: a systematic review and network meta-analysis – European Respiratory Review

 


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