Systematic Reviews & Meta-analysis
M-A | Treatment efficacy and effectiveness in adults with major depressive disorder and childhood trauma history.
27 Sep, 2022 | 13:01h | UTCTreatment efficacy and effectiveness in adults with major depressive disorder and childhood trauma history: a systematic review and meta-analysis – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/TheLancetPsych/status/1573247063844089857
M-A | Optimal pharmacologic treatment of heart failure with preserved and mildly reduced ejection fraction.
22 Sep, 2022 | 13:05h | UTCRelated M-A: SGLT-2 inhibitors in patients with heart failure: a comprehensive meta-analysis of five randomised controlled trials – The Lancet (link to abstract – $ for full-text)
M-A of randomized trials | Prophylactic central neck lymph node dissection in low-risk thyroid carcinoma patients does not decrease the incidence of locoregional recurrence.
21 Sep, 2022 | 13:07h | UTCProphylactic Central Neck Lymph Node Dissection in Low-risk Thyroid Carcinoma Patients Does Not Decrease the Incidence of Locoregional Recurrence: A Meta-analysis of Randomized Trials – Annals of Surgery (link to abstract – $ for full-text)
M-A of randomized trials | Hyperthermic intraperitoneal chemotherapy (HIPEC) for the management of primary advanced and recurrent ovarian cancer.
20 Sep, 2022 | 13:23h | UTCRelated:
Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer – New England Journal of Medicine
M-A of randomized trials | Effectiveness and cost-effectiveness of oral nutritional supplements in frail older people who are malnourished or at risk of malnutrition.
20 Sep, 2022 | 13:24h | UTCInvited Commentary: Do oral nutritional supplements effectively reduce malnutrition or its adverse outcomes in older people with frailty? – The Lancet Health Longevity
M-A of randomized trials | Transanal tube vs. defunctioning stoma after low anterior resection for rectal cancer.
19 Sep, 2022 | 12:37h | UTC
M-A | Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide.
19 Sep, 2022 | 12:36h | UTC
M-A of randomized trials | Ondansetron vs. Metoclopramide for managing hyperemesis gravidarum.
19 Sep, 2022 | 12:34h | UTCCommentary: Ondansetron or metoclopramide, which is better for managing hyperemesis gravidarum? – Medical Dialogues
Systematic Review | The effects of water compared with other solutions for wound cleansing – not enough evidence to guide recommendations.
16 Sep, 2022 | 12:52h | UTCWater for wound cleansing – Cochrane Library
Summary: The effects of water compared with other solutions for wound cleansing – Cochrane Library
M-A | Role of pessaries in the treatment of pelvic organ prolapse.
15 Sep, 2022 | 13:08h | UTCRole of Pessaries in the Treatment of Pelvic Organ Prolapse: A Systematic Review and Meta-analysis – Obstetrics & Gynecology (free for a limited period)
Systematic Review | Interventions for improving mobility after hip fracture surgery in adults.
14 Sep, 2022 | 13:11h | UTCInterventions for improving mobility after hip fracture surgery in adults – Cochrane Library
Commentary from the author on Twitter
Pleased to have our Cochrane review on mobility training after hip fracture out today. Key message “extra exercises targeting balance, walking and functional tasks appear effective in improving mobility in hospital and after discharge.” @msk_health https://t.co/vLbGWKZWgp
— Prof Cathie Sherrington (@CathieSherr) September 7, 2022
Systematic Review | Maternal postures for fetal malposition in labor for improving the health of mothers and their infants.
14 Sep, 2022 | 13:12h | UTCSummary: Mothers’ positions in labour when baby is lying ‘back-to-back’ – Cochrane Library
M-A | Antibiotic use in ambulatory care for acutely ill children in high-income countries.
14 Sep, 2022 | 13:10h | UTC
M-A of randomized trials | Digital health interventions for musculoskeletal pain conditions.
14 Sep, 2022 | 13:08h | UTC
M-A of randomized trials | Effectiveness of work-related interventions for return to work in people on sick leave.
14 Sep, 2022 | 13:08h | UTC
M-A | The effectiveness of self-care interventions in chronic illness.
14 Sep, 2022 | 13:03h | UTC
Dementia: evidence, experience and resources.
13 Sep, 2022 | 13:20h | UTCDementia: evidence, experience and resources – Evidently Cochrane
M-A of randomized trials | High-flow nasal cannula oxygen therapy vs. non-invasive ventilation for patients with acute exacerbation of COPD after extubation.
13 Sep, 2022 | 13:00h | UTC
Systematic Review | Listening to music for insomnia in adults.
13 Sep, 2022 | 12:55h | UTCListening to music for insomnia in adults – Cochrane Library
Systematic Review | Adding rapid diagnostic tests to community‐based programs for treating malaria.
13 Sep, 2022 | 12:57h | UTCAdding rapid diagnostic tests to community‐based programmes for treating malaria – Cochrane Library
Systematic Review | Ultra‐radical (extensive) surgery vs. standard surgery for the primary cytoreduction of advanced epithelial ovarian cancer.
13 Sep, 2022 | 12:56h | UTCRelated Study: Randomized Trial of Cytoreductive Surgery for Relapsed Ovarian Cancer – New England Journal of Medicine
Network M-A | Comparative efficacy of lipid‐lowering therapies added to maximally tolerated statins for the reduction of LDL cholesterol.
11 Sep, 2022 | 22:38h | UTC
M-A | Performance of single serum progesterone in the evaluation of symptomatic first-trimester pregnant patients.
11 Sep, 2022 | 22:32h | UTCPerformance of single serum progesterone in the evaluation of symptomatic first-trimester pregnant patients: a systematic review and meta-analysis – Canadian Journal of Emergency Medicine (if the link is paywalled, try this one)
Systematic Review | Long-term outcomes after non-traumatic out-of-hospital cardiac arrest in pediatric patients.
11 Sep, 2022 | 22:30h | UTC
Systematic Review | Surgery for the treatment of obesity in children and adolescents.
11 Sep, 2022 | 22:29h | UTCSurgery for the treatment of obesity in children and adolescents – Cochrane Library
Summary: Surgery for the treatment of obesity in children and adolescents – Cochrane Library


