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Systematic Reviews & Meta-analysis

M-A | Efficacy and safety of treatments in newly diagnosed adult primary immune thrombocytopenia

9 Feb, 2023 | 13:30h | UTC

Efficacy and safety of treatments in newly diagnosed adult primary immune thrombocytopenia: A systematic review and network meta-analysis – eClinicalMedicine

 


M-A | Prevalence of polypharmacy and potentially inappropriate medication use in older lung cancer patients

9 Feb, 2023 | 13:24h | UTC

Prevalence of polypharmacy and potentially inappropriate medication use in older lung cancer patients: A systematic review and meta-analysis – Frontiers in Pharmacology

 


M-A | Comparative antiseizure medications for adjunctive treatment in children with drug-resistant focal-onset seizures

9 Feb, 2023 | 13:22h | UTC

Comparative antiseizure medications of adjunctive treatment for children with drug-resistant focal-onset seizures: A systematic review and network meta-analysis – Frontiers in Pharmacology

 


M-A | Needle-free pharmacological sedation techniques in pediatric patients for imaging procedures

8 Feb, 2023 | 12:26h | UTC

Needle-free pharmacological sedation techniques in paediatric patients for imaging procedures: a systematic review and meta-analysis – British Journal of Anaesthesia

 


M-A | Intranasal midazolam vs. intranasal ketamine as sedative premedication in pediatric patients

8 Feb, 2023 | 12:24h | UTC

Efficacy and safety of intranasal midazolam versus intranasal ketamine as sedative premedication in pediatric patients: a meta-analysis of randomized controlled trials – BMC Anesthesiology

 


M-A | Risk of endometrial cancer in postmenopausal women in relation to ultrasonographic endometrial thickness

8 Feb, 2023 | 12:21h | UTC

Risk of endometrial cancer in asymptomatic postmenopausal women in relation to ultrasonographic endometrial thickness: systematic review and diagnostic test accuracy meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


M-A | Dual antiplatelet therapy duration after percutaneous coronary intervention in high bleeding risk

8 Feb, 2023 | 12:16h | UTC

Dual antiplatelet therapy duration after percutaneous coronary intervention in high bleeding risk: a meta-analysis of randomized trials – European Heart Journal (link to abstract – $ for full-text)

 

Commentary on Twitter

 


M-A | Efficacy of treatments for children, adolescents, and young adults with Tourette’s syndrome

8 Feb, 2023 | 12:13h | UTC

Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette’s syndrome: a systematic review and network meta-analysis – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)

 

Commentary on Twitter

 


SR | Sodium assessment in neonates, infants, and children

8 Feb, 2023 | 12:01h | UTC

Sodium assessment in neonates, infants, and children: a systematic review – European Journal of Pediatrics

 


SR | Calcium and vitamin D supplements do not increase bone mineral density or prevent fractures in premenopausal women

7 Feb, 2023 | 14:18h | UTC

Calcium and vitamin D for increasing bone mineral density in premenopausal women – Cochrane Library

Summary: Calcium and vitamin D for improving bone health in healthy premenopausal women – Cochrane Library

 


SR | The current evidence does not support a role for Vitamin D in the management of asthma

7 Feb, 2023 | 14:16h | UTC

Vitamin D for the management of asthma – Cochrane Library

Commentary: Vitamin D for asthma: new evidence, new message – Evidently Cochrane

 


M-A | Heparin full-dose anticoagulation is beneficial for non-critically ill COVID-19 patients

7 Feb, 2023 | 14:06h | UTC

The Effect of Heparin Full-Dose Anticoagulation on Survival of Hospitalized, Non-critically Ill COVID-19 Patients: A Meta-analysis of High Quality Studies – Lung

Related:

#ESCCongress | In critically ill patients with COVID-19, full-dose anticoagulation reduced thrombotic events but increased the risk of bleeding.

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

Efficacy and safety of heparin full-dose anticoagulation in hospitalized non-critically ill COVID-19 patients: a meta-analysis of multicenter randomized controlled trials – Journal of Thrombosis and Thrombolysis

Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19: a systematic review and meta-analysis – Open Forum Infectious Diseases

Point/Counterpoint: Should therapeutic heparin be administered to acutely ill hospitalized patients with COVID-19?

 


SR | Cognitive stimulation to improve cognitive functioning in people with dementia

7 Feb, 2023 | 13:59h | UTC

Cognitive stimulation to improve cognitive functioning in people with dementia – Cochrane Library

Summary: Can cognitive stimulation benefit people with dementia? – Cochrane Library

 


SR | Intravenous immunoglobulin for the treatment of Kawasaki disease

7 Feb, 2023 | 13:58h | UTC

Intravenous immunoglobulin for the treatment of Kawasaki disease – Cochrane Library

Summary: Immunoglobulin treatment for Kawasaki disease – Cochrane Library

Related:

Analysis of Coronary Arterial Aneurysm Regression in Patients With Kawasaki Disease by Aneurysm Severity: Factors Associated With Regression – Journal of the American Heart Association

Analysis of Age, Sex, Lack of Response to Intravenous Immunoglobulin, and Development of Coronary Artery Abnormalities in Children With Kawasaki Disease in Japan – JAMA Network Open

Systematic Review: Corticosteroids for the treatment of Kawasaki disease in children.

Pharmacologic interventions for Kawasaki disease in children: A network meta-analysis of 56 randomized controlled trials.

2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Kawasaki Disease

Anti-inflammatory Treatment of Kawasaki Disease: Comparison of Current Guidelines and Perspectives – Frontiers in Medicine

 


M-A | Above elbow vs. below elbow immobilization for conservative treatment of distal end radius fracture in adults

7 Feb, 2023 | 13:49h | UTC

Comparison of above elbow and below elbow immobilisation for conservative treatment of distal end radius fracture in adults: A systematic review and meta-analysis of randomized clinical trials – Chinese Journal of Traumatology

 


M-A | Effectiveness of therapeutic exercise models on cancer-related fatigue

7 Feb, 2023 | 13:46h | UTC

Effectiveness of Therapeutic Exercise Models on Cancer-Related Fatigue in Patients with Cancer Undergoing Chemotherapy: A Systematic Review and Network Meta-Analysis – Archives of Physical Medicine and Rehabilitation

Commentary: What is the effectiveness of different exercise modalities in reducing cancer-related fatigue in cancer patients undergoing chemotherapy? – News Medical

Related:

ASCO Guideline: Exercise, diet, and weight management during cancer treatment.

A systematic review of rehabilitation and exercise recommendations in oncology guidelines

Five reasons physical activity is important for cancer patients – The Conversation

RCT | Effects of a physical exercise intervention during vs. after chemotherapy to improve cardiorespiratory fitness.

 


M-A | Effect of early childhood development interventions to improve cognitive outcomes in children at 0–36 months

6 Feb, 2023 | 13:14h | UTC

Effect of early childhood development interventions delivered by healthcare providers to improve cognitive outcomes in children at 0–36 months: a systematic review and meta-analysis – Archives of Disease in Childhood (free for a limited period)

 


M-A | Cardiac resynchronization may improve outcomes in patients with intraventricular conduction delay but not in those with RBBB

6 Feb, 2023 | 13:13h | UTC

Cardiac Resynchronization Therapy Improves Outcomes in Patients With Intraventricular Conduction Delay But Not Right Bundle Branch Block: A Patient-Level Meta-Analysis of Randomized Controlled Trials – Circulation (free for a limited period)

Commentary: CRT Likely Benefits Broader Group of Patients: Meta-analysis – TCTMD

 

Commentary on Twitter

 


M-A | Risk of second primary cancer among breast cancer patients

6 Feb, 2023 | 13:10h | UTC

Risk of second primary cancer among breast cancer patients: A systematic review and meta-analysis – Frontiers in Oncology

 


SR | Efficacy of CAR-T cell therapy vs. auto-HSCT in relapsed or refractory diffuse large B-cell lymphoma

6 Feb, 2023 | 13:06h | UTC

Efficacy of chimeric antigen receptor T cell therapy and autologous stem cell transplant in relapsed or refractory diffuse large B-cell lymphoma: A systematic review – Frontiers in Immunology

 


SR | Which interventions decrease ED attendances or hospital admissions from long-term care facilities?

6 Feb, 2023 | 13:04h | UTC

Which interventions are effective at decreasing or increasing emergency department attendances or hospital admissions from long-term care facilities? A systematic review – BMJ Open

 

Commentary from the author on Twitter (thread – click for more)

 


M-A | Evaluation of comparative efficacy and safety of surgical approaches for total hip arthroplasty

6 Feb, 2023 | 13:01h | UTC

Evaluation of Comparative Efficacy and Safety of Surgical Approaches for Total Hip Arthroplasty: A Systematic Review and Network Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


M-A | Efficacy and safety of dietary therapies for childhood drug-resistant epilepsy

6 Feb, 2023 | 13:00h | UTC

Efficacy and Safety of Dietary Therapies for Childhood Drug-Resistant Epilepsy: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (link to abstract – $ for full-text)

Related:

RCT | Safety, efficacy, and tolerability of modified Atkins diet in persons with drug-resistant epilepsy

Efficacy of Ketogenic Diet, Modified Atkins Diet, and Low Glycemic Index Therapy Diet Among Children With Drug-Resistant Epilepsy: A Randomized Clinical Trial – JAMA Pediatrics

 

Commentary on Twitter

 


M-A | Types and concentrations of blood-based biomarkers in adults with peripheral neuropathies

3 Feb, 2023 | 13:49h | UTC

Types and Concentrations of Blood-Based Biomarkers in Adults With Peripheral Neuropathies: A Systematic Review and Meta-analysis – JAMA Network Open

 


M-A | Major complications and mortality after resection of intrahepatic cholangiocarcinoma

3 Feb, 2023 | 13:43h | UTC

Major complications and mortality after resection of intrahepatic cholangiocarcinoma: A systematic review and meta-analysis – Surgery

 


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