Psychiatry
Living through the psychological consequences of COVID-19 pandemic: a systematic review of effective mitigating interventions.
16 Aug, 2022 | 13:43h | UTC
RCT | Therapist-supported internet-delivered exposure and response prevention for children and adolescents with Tourette Syndrome.
16 Aug, 2022 | 13:18h | UTCCommentaries:
Online Exposure Therapy Improves Tic Symptoms in Youth – Psychiatric News Alert
Commentary on Twitter
In this RCT, 221 youths with #Tourette syndrome or chronic tic disorder received therapist-supported, internet-delivered exposure and response prevention (ERP) or education. Both groups improved over time, with no between-group differences in tic severity. https://t.co/YND2mgPn2Q
— JAMA Network Open (@JAMANetworkOpen) August 15, 2022
Cohort Study | Clinical correlates and outcomes of methamphetamine‐associated cardiovascular diseases in hospitalized patients.
16 Aug, 2022 | 13:03h | UTCCommentary: Methamphetamine use associated with cardiovascular disease in hospitalized patients – Physician’s Weekly
Commentary on Twitter
In one of the largest studies to date, Curran et al. found that #methamphetamine use is as big a risk for #heart #disease as alcohol and cocaine. @UCSFCardiology @LaraGroom #AHAJournals https://t.co/S82YLoVM7r pic.twitter.com/SkmxF3bG7d
— JAHA (@JAHA_AHA) August 12, 2022
Non-parenteral Ketamine for depression: a practical discussion on addiction potential and recommendations for judicious prescribing.
10 Aug, 2022 | 12:19h | UTC
RCT | Effectiveness of Varenicline and Cytisine for alcohol use reduction among people with HIV and substance use.
9 Aug, 2022 | 12:35h | UTC
Commentary on Twitter
In this RCT, varenicline and cytisine were not more efficacious than nicotine to treat risky drinking and smoking among individuals with HIV; rates of behavior change for alcohol consumption and smoking were high in all treatment groups. #OrigInvestigation https://t.co/h8M6e5nOkf
— JAMA Network Open (@JAMANetworkOpen) August 5, 2022
Real-world effectiveness of antipsychotic doses for relapse prevention in patients with first-episode schizophrenia in Finland: a nationwide, register-based cohort study.
5 Aug, 2022 | 14:31h | UTCReal-world effectiveness of antipsychotic doses for relapse prevention in patients with first-episode schizophrenia in Finland: a nationwide, register-based cohort study – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
cohort study in 1st-episode schizophrenia: The effectiveness of antipsychotics for relapse prevention decreased after the 2nd relapse. The aHR for rehospitalisation with AP use versus non-use increased from 0·42 to 0·78 after the 2nd relapse (p<0·0001) https://t.co/IBhDPNJJpe?
— P𝘧OL (@psychopharmacol) March 18, 2022
Review | Adults with intellectual disabilities and mental health disorders in primary care.
5 Aug, 2022 | 14:24h | UTC
Review | Recognizing and managing eating disorders in the emergency department.
5 Aug, 2022 | 14:22h | UTCRecognising and managing eating disorders in the emergency department – Postgraduate Medical Journal
Cohort Study | The risk of opioid overdose is increased with concomitant use of oxycodone and selective serotonin reuptake inhibitors that are inhibitors of oxycodone metabolism.
4 Aug, 2022 | 14:27h | UTCCommentary from the author: Taking certain opioids while on commonly prescribed antidepressants may increase the risk of overdose – The Conversation
Commentary on Twitter
This cohort study found that concomitant use of oxycodone with potent CYP2D6-inhibiting serotonin reuptake inhibitors (SSRIs, eg. fluoxetine or paroxetine) is associated with an increased risk of overdose. https://t.co/Eol89RHWAu
— JAMA Network Open (@JAMANetworkOpen) February 24, 2022
Cohort Study | Bariatric surgery linked to doubling chance of marriage or divorce.
4 Aug, 2022 | 14:16h | UTCNews Release: Bariatric Surgery Linked to Doubling Chance of Marriage or Divorce – University of Pittsburgh
Commentary: Spouse Getting Weight Loss Surgery? Your Marriage Might Be in Trouble – HealthDay
RCT | Transcranial direct current stimulation vs. sham for the treatment of inattention in adults with attention-deficit/hyperactivity disorder.
4 Aug, 2022 | 13:50h | UTCTranscranial Direct Current Stimulation vs Sham for the Treatment of Inattention in Adults With Attention-Deficit/Hyperactivity Disorder: The TUNED Randomized Clinical Trial – JAMA Psychiatry (free for a limited period)
See also: Visual Abstract
M-A | Response to acute monotherapy for major depressive disorder in randomized, placebo controlled trials.
3 Aug, 2022 | 14:31h | UTC
M-A | Prevalence of suicidal ideation and self-harm behaviors in children aged 12 years and younger.
1 Aug, 2022 | 12:01h | UTCPrevalence of suicidal ideation and self-harm behaviours in children aged 12 years and younger: a systematic review and meta-analysis – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter
*New* systematic review & meta-analysis estimates a prevalence of 7·5% for suicidal ideation, 2·2% for suicide planning, 1·4% for self-harm, 1·3% for suicide attempts, & 21·9% for non-suicidal self-injury in children aged ≤12 years
In @TheLancetPsych #childhoodsuicide https://t.co/wFbv6eKpNs
— The Lancet Child & Adolescent Health (@LancetChildAdol) July 28, 2022
RCT | Efficacy and safety of viloxazine extended-release capsules in adults with attention-deficit/hyperactivity disorder.
1 Aug, 2022 | 11:57h | UTC
A large observational study suggests long-acting injectable antipsychotics are associated with better outcomes than oral antipsychotics in people with schizophrenia.
29 Jul, 2022 | 12:25h | UTCInvited Commentary: Improving Outcomes in Schizophrenia—A Case for Initiation of Long-Acting Antipsychotics in Early-Phase Illness – JAMA Network Open
Related:
Long-term Outcomes of Early Use of Long-Acting Injectable Antipsychotics in Schizophrenia – The Journal of Clinical Psychiatry (link to abstract – $ for full-text)
Comparative efficacy and tolerability of 32 oral and long-acting injectable antipsychotics for the maintenance treatment of adults with schizophrenia: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)
Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised, cohort, and pre–post studies – The Lancet Psychiatry (link to abstract – $ for full-text)
Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised, cohort, and pre–post studies – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter
This case series of people with schizophrenia found long-acting injectable antipsychotics were associated with less disease relapse and hospitalization vs oral antipsychotics, w/o an increased risk of adverse events. @Esther_CSMPRHKU @HKUPharm @hkumed https://t.co/ZiPkV4lSk0
— JAMA Network Open (@JAMANetworkOpen) July 28, 2022
M-A | Socioeconomic indicators of treatment prognosis for adults with depression.
29 Jul, 2022 | 12:17h | UTCNews Release: People without jobs or secure housing have worse outcomes when treated for depression – University College London
Commentary on Twitter
Socioeconomic disadvantage in employment and housing is associated with considerably worse outcomes in #depression, regardless of treatment type and after adjusting for clinical prognostic factors. https://t.co/bVTQv5zx8C
— JAMA Psychiatry (@JAMAPsych) May 6, 2022
Perspective | Climbing melatonin use for insomnia raises safety concerns.
28 Jul, 2022 | 13:24h | UTCClimbing Melatonin Use for Insomnia Raises Safety Concerns – JAMA (free for a limited period)
RCT | Vitamin B6 supplements could reduce anxiety and depression.
27 Jul, 2022 | 12:19h | UTCNews Release: Vitamin B6 supplements could reduce anxiety and depression – University of Reading
Commentary: B6 a New Approach for Depression, Anxiety? – Medscape (free registration required)
RCT | Effectiveness of intensive home treatment as a substitute for hospital admission in acute psychiatric crisis resolution.
27 Jul, 2022 | 12:08h | UTCThe effectiveness of intensive home treatment as a substitute for hospital admission in acute psychiatric crisis resolution in the Netherlands: a two-centre Zelen double-consent randomised controlled trial – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary: Intensive home treatment effective in place of hospital admission for psychiatric crisis – Healio (free registration required)
Commentary on Twitter
https://twitter.com/TheLancetPsych/status/1544594945331412992
M-A | Comparison of the efficacy and safety of quetiapine and lithium for bipolar depression.
27 Jul, 2022 | 11:55h | UTC
Systematic Review | Cognitive behavioral therapy (group) for schizophrenia.
25 Jul, 2022 | 12:48h | UTCCognitive behavioural therapy (group) for schizophrenia – Cochrane Library
Summary: Group cognitive behavioural therapy for schizophrenia – Cochrane Library
RCT | Flexible buprenorphine/naloxone model of care for reducing opioid use in individuals with prescription-type opioid use disorder.
22 Jul, 2022 | 11:38h | UTCNews Release: Opioid use disorder: Flexible treatment at home proves effective – University of Montreal Hospital Research Centre
Systematic Review | Extended‐release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults.
22 Jul, 2022 | 11:24h | UTC
Commentary on Twitter
https://twitter.com/CochraneLibrary/status/1498303886909657097
M-A | Family interventions for relapse prevention in schizophrenia.
22 Jul, 2022 | 11:22h | UTCFamily interventions for relapse prevention in schizophrenia: a systematic review and network meta-analysis – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary: Almost All Family Interventions Can Prevent Relapse in Schizophrenia – HealthDay
Commentary on Twitter
https://twitter.com/TheLancetPsych/status/1487154374325547016
Comprehensive review finds little evidence that depression is caused by an imbalance of serotonin in the brain.
21 Jul, 2022 | 13:29h | UTCNews Release: No evidence that depression is caused by low serotonin levels, finds comprehensive review – University College London
Commentary from the authors: Depression is probably not caused by a chemical imbalance in the brain – new study – The Conversation
Other commentaries:
Expert reaction to a review paper on the ‘serotonin theory of depression’ – Science Media Centre
Little evidence that chemical imbalance causes depression, UCL scientists find – The Guardian


