Pharmacology/Pharmaceutical Industry
Systematic Review: Corticosteroid versus NSAIDs for the Treatment of Acute Gout
15 Sep, 2017 | 19:14h | UTCSource: EvidenceAlerts
Corticosteroids and NSAIDs did not have different effects on pain scores, but there was a higher risk of indigestion, nausea and vomiting with NSAIDs.
A range of anti-epilepsy drugs are effective as first-line treatment
15 Sep, 2017 | 19:10h | UTCA range of anti-epilepsy drugs are effective as first-line treatment – NIHR Signal (free)
Original article: Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data – Cochrane Library (link to abstract – $ for full-text)
Review: Osteoporosis drug treatment: duration and management after discontinuation
15 Sep, 2017 | 19:09h | UTC
Study: Final efficacy, immunogenicity, and safety analyses of a nine-valent human papillomavirus vaccine
14 Sep, 2017 | 20:45h | UTCFinal efficacy, immunogenicity, and safety analyses of a nine-valent human papillomavirus vaccine in women aged 16–26 years: a randomised, double-blind trial – The Lancet (link to abstract – $ for full-text)
Commentary: Vaccine to prevent most cervical cancers shows long-term effectiveness – eCancer News (free)
Study: Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease
14 Sep, 2017 | 20:51h | UTCTiotropium in Early-Stage Chronic Obstructive Pulmonary Disease – The New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Drug may slow early lung disease damage – Reuters (free) AND Tiotropium Boosts Lung Function in Early COPD – MedPage Today (free)
Guideline: Treatment of Type 1 Diabetes
12 Sep, 2017 | 21:11h | UTC
WHO Guideline: Hormonal contraceptive eligibility for women at high risk of HIV
12 Sep, 2017 | 21:05h | UTCHormonal contraceptive eligibility for women at high risk of HIV: Guidance Statement – World Health Organization (free PDF)
News release: Can women who are at high risk of acquiring HIV, safely use hormonal contraception? (free)
Frequently asked questions: Hormonal contraceptive eligibility for women at high risk of HIV (free)
Guideline Summary: Hormonal contraceptive eligibility for women at high risk of HIV: guidance statement – National Guideline Clearinghouse (free)
Review: Adverse effects of proton-pump inhibitor use in older adults
12 Sep, 2017 | 20:58h | UTC
Review: The Nephrotoxicity of Vancomycin
12 Sep, 2017 | 20:53h | UTCThe Nephrotoxicity of Vancomycin – Clinical Pharmacology & Therapeutics (free)
Recommendations for the treatment of hepatitis B
12 Sep, 2017 | 20:51h | UTCRecommendations for the treatment of hepatitis B in 2017 – Polish Group of Experts for HBV (free)
Recommendations for the treatment of hepatitis C
12 Sep, 2017 | 20:50h | UTCRecommendations for the treatment of hepatitis C in 2017 – Polish Group of Experts for HCV (free)
FDA approves new drug for complicated UTI
11 Sep, 2017 | 14:32h | UTCFDA News Release: FDA approves new antibacterial drug (free)
FDA approves new drug for complicated urinary tract infection – CIDRAP (free) AND FDA OKs Vabomere, New Antibacterial for Complicated UTI – Medscape (free registration Required)
Free Online Course: PrEP for Providers and Patients
11 Sep, 2017 | 00:58h | UTCStarts Today! Free Online Course: PrEParing: PrEP for Providers and Patients – Johns Hopkins University and Coursera
11 Drugs You Should Seriously Consider Deprescribing
11 Sep, 2017 | 00:24h | UTC11 Drugs You Should Seriously Consider Deprescribing – Medscape Slideshow (free registration required)
Related: Canadian Deprescribing Network (CaDeN) (free) AND CaDeN Deprescribing Guidelines and Algorithms (free) AND Deprescribing guidelines for the elderly – Ontario Pharmacy Evidence Network (free) AND Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Too Many Meds? America’s Love Affair With Prescription Medication – Consumer Reports (free) AND Patient often prescribed potentially futile drugs in their final months of life – Science Daily AND The Challenge of Polypharmacy: From Rhetoric to Reality – Royal Pharmaceutical Society and Royal College of General Practitioners Partnership (free PDF) Current and future perspectives on the management of polypharmacy – BMC Family Practice (free)
Medication Adherence in Hypertension: The Role of Patient–Provider Communication
11 Sep, 2017 | 00:21h | UTCEditorial: Talking With Patients Is Better Than Talking to Patients (free)
Commentaries: Hypertension Medication Adherence May Be Improved by Collaborate Communication – Cardiology Advisor (free) AND Better Provider Communication Might Improve Medication Adherence – Medscape (free registration required) AND Talk Why, Not What for Better Antihypertensive Adherence – MedPage Today (free)
“Odds of poor med adherence 6x greater when patient-provider interactions don’t address patients’ unmet social needs” (RT @CircOutcomes see Tweet)
Study: Safety and Feasibility of Antiretroviral Preexposure Prophylaxis for Adolescent Men Who Have Sex With Men
10 Sep, 2017 | 01:30h | UTCEditorial: Human Immunodeficiency Virus Preexposure Prophylaxis for Adolescent Men (free)
Commentaries: Safety, Feasibility of PrEP for Adolescent Men Who Have Sex With Men – The JAMA Network (free) AND PrEP safe and effective for young men who have sex with men – OnMedica (free) AND HIV PrEP for adolescent men found to be safe, effective – UPI (free)
Study: Antipsychotic Use With and Without Comorbid Psychiatric Diagnosis Among Adults with Intellectual and Developmental Disabilities
10 Sep, 2017 | 01:31h | UTCAntipsychotic Use With and Without Comorbid Psychiatric Diagnosis Among Adults with Intellectual and Developmental Disabilities – The Canadian Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Antipsychotics common for adults with intellectual and developmental disabilities – Centre for Addiction and Mental Health (free) AND Antipsychotics Overused in Intellectually Disabled Adults – Medscape (free registration required)
“Antipsychotics are used inappropriately particularly in vulnerable groups: Poor children; Intellectually challenged; Autistic; Nursing homes. (RT @AllenFrancesMD see Tweet)
Review: Molecular Targeted Drugs and Treatment of Colorectal Cancer
9 Sep, 2017 | 22:08h | UTCCommentary: Review highlights significant progress in developing new biologic drugs to treat colorectal cancer – News Medical (free)
Study: Differential blood pressure effects of ibuprofen, naproxen, and celecoxib in patients with arthritis
9 Sep, 2017 | 22:16h | UTCCommentaries: Under Pressure: PRECISION Substudy Shows Adverse BP Effects of Ibuprofen – TCTMD (free) AND Increases in BP, Hypertension Incidence Linked to Certain NSAIDs – MPR (free) AND Ibuprofen Ups Systolic BP, New-Onset Hypertension Risk – Medscape (free registration required)
Systematic Review: Toxicity of Extended Adjuvant Therapy With Aromatase Inhibitors in Early Breast Cancer
9 Sep, 2017 | 21:29h | UTCToxicity of Extended Adjuvant Therapy With Aromatase Inhibitors in Early Breast Cancer: A Systematic Review and Meta-analysis – Journal of the National Cancer Institute (link to abstract – $ for full-text)
Commentary: Extended AI Use Linked to CV Events and Bone Fractures – Medscape (free registration required)
Guideline: Acute and Postoperative Pain Management in Oral and Maxillofacial Surgery
9 Sep, 2017 | 22:05h | UTCCommentary: AAOMS: Prescribing Recommendations for Acute and Post-Op Pain – MPR (free)
Should kids be sedated for dental work?
9 Sep, 2017 | 17:18h | UTCShould kids be sedated for dental work? – The New York Times (10 articles per month are free)
Related guideline: Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures: Update 2016 (free)
Stop smoking services can work for people in treatment or recovery from substance misuse disorders
9 Sep, 2017 | 18:30h | UTCStop smoking services can work for people in treatment or recovery from substance misuse disorders – NIHR Signal (free)
Original article: Interventions for tobacco use cessation in people in treatment for or recovery from substance use disorders – Cochrane Library (link to abstract – $ for full-text)
Meta-analysis: Use of supplemental long-chain omega-3 fatty acids and risk for cardiac death
9 Sep, 2017 | 16:03h | UTCCommentary: Omega-3 Intake Reduces Cardiac Death Risk – Pharmacy Practice Reviews (free registration required)
Related guideline and commentaries: Omega-3 Polyunsaturated Fatty Acid (Fish Oil) Supplementation and the Prevention of Clinical Cardiovascular Disease: A Science Advisory from the American Heart Association (free PDF) AND Commentary: Omega-3 Fish Oil Supplements – Taking Stock and Awaiting Vital New Studies (free) AND AHA News: Fish oil supplements provide some benefit after heart attack, heart failure (free) AND News Release: Fish oil supplements may help prevent death after a heart attack but lack evidence of cardiovascular benefit for the general population – American Heart Association Science Advisory (free) AND Top Ten Things to Know (free PDF)
Cohort Study: Cardiovascular disease risk and androgen deprivation therapy in patients with prostate cancer
9 Sep, 2017 | 14:28h | UTCCardiovascular disease risk and androgen deprivation therapy in patients with localised prostate cancer: a prospective cohort study – British Journal of Cancer (link to abstract – $ for full-text)
Commentaries: Prostate cancer treatment associated with higher risk of heart failure – Cardiovascular Business (free) AND Hormone Treatment for Prostate Cancer Tied to Heart Risks – New York Times (10 articles per month are free)