Pharmacology/Pharmaceutical Industry
Research: Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients Receiving Palliative Care
1 Oct, 2017 | 15:04h | UTCEffect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Lorazepam, Haloperidol, and Delirium – Pallimed (free) AND Drug Combo Found Helpful in End-of-Life Delirium – MedPage Today (free registration required) AND Lorazepam Plus Haloperidol Improves Agitation in Cancer-Related Delirium – OncologyNurse Advisor (free)
Review: Combined hormonal contraceptives and migraine
1 Oct, 2017 | 14:45h | UTC
Review: Delirium in hospitalized patients: Risks and benefits of antipsychotics
1 Oct, 2017 | 14:43h | UTC
Risk factors for admission to hospital with laboratory-confirmed influenza in young children
30 Sep, 2017 | 13:39h | UTCRisk factors for admission to hospital with laboratory-confirmed influenza in young children: birth cohort study – European Respiratory Journal (link to abstract – $ for full-text)
Commentaries: Protect babies from flu by getting older siblings vaccinated, parents advised – The Guardian (free) AND Older Siblings a Risk Factor for Serious Flu Infections in Infants – The New York Times (10 articles per month are free)
Guideline: Urinary tract infection in under 16s: diagnosis and management
30 Sep, 2017 | 13:27h | UTCNICE Guideline: Urinary tract infection in under 16s: diagnosis and management (free)
News Release: Test children’s urine before prescribing antibiotics for UTIs, says NICE (free)
Systematic review: benefits and risks of phosphodiesterase 4 inhibitors in COPD
30 Sep, 2017 | 13:21h | UTCOriginal Article: Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease – Cochrane Library (link to abstract – $ for full-text))
Statement on the Impact of Utilization Management Policies for Cancer Drug Therapies
30 Sep, 2017 | 13:20h | UTCCommentary: ASCO on Utilization Policies for Ca Therapy – Oncology Practice (free registration required)
Randomized Trial: Once-Daily Triple Therapy for Patients with COPD
30 Sep, 2017 | 13:19h | UTCFULFIL Trial: Once-Daily Triple Therapy for Patients with Chronic Obstructive Pulmonary Disease – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentary: Once-Daily Triple Therapy Effective in Patients With COPD – Pulmonology Advisor (free)
Source: Journal Watch ($)
Meta-analysis: monotherapy of donepezil versus combination with memantine for Alzheimer disease
30 Sep, 2017 | 13:17h | UTCSource: Journal Watch ($)
Meta-analysis: Efficacy of pancreatic enzyme replacement therapy in chronic pancreatitis
27 Sep, 2017 | 14:47h | UTCSource: Medscape
Cohort Study: Risk of gastrointestinal perforation in patients taking fluoroquinolones
27 Sep, 2017 | 14:48h | UTCCommentary: Antibiotic Class Linked to Increased Risk of GI Perforation – MPR (free)
Review: Using Best Evidence for the Management of Hypertension
27 Sep, 2017 | 14:46h | UTCUsing Best Evidence for the Management of Hypertension – Therapeutics Initiative (free)
Guideline: Treating tobacco dependence
27 Sep, 2017 | 14:19h | UTC
Guideline for the diagnosis and treatment of insomnia
27 Sep, 2017 | 14:18h | UTCEuropean guideline for the diagnosis and treatment of insomnia – European Sleep Research Society (free)
Meta-analysis: Efficacy of recommended drugs against soil transmitted helminths
27 Sep, 2017 | 14:04h | UTCCommentary: Reduced Efficacy of Anthelmintic Drugs – MyScience (free)
Pregnant Women Should Still Get The Flu Vaccine, Doctors Advise
27 Sep, 2017 | 13:58h | UTCPregnant Women Should Still Get The Flu Vaccine, Doctors Advise – NPR (free)
Statement: It is Safe to Receive Flu Shot During Pregnancy – American College of Obstetricians and Gynecologists (free)
See original study showing a possible association between flu vaccine and miscarriage in our September 21st issue (see #6)
Randomized Controled Trial: Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control
27 Sep, 2017 | 14:02h | UTCEffect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty: The GIFT Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Genotyping Reduces Adverse Events with Warfarin – Cardiobrief (free) AND Genotype-Guided Warfarin Dosing Reduces Adverse Events After Hip, Knee Arthroplasty – Physician’s First Watch (free)
Draft Guideline: Most common ear infections should not be treated with antibiotics
25 Sep, 2017 | 22:28h | UTCNews release: Draft Guideline: Most common ear infections should not be treated with antibiotics, says NICE (free)
Commentaries: Common ear infections don’t need antibiotics, health watchdog says – The Guardian (free) AND Antibiotics not recommended for acute otitis, says NICE (free)
Cohort Study: Low-Dose Aspirin Discontinuation and Risk of Cardiovascular Events
25 Sep, 2017 | 22:27h | UTCLow-Dose Aspirin Discontinuation and Risk of Cardiovascular Events: A Swedish Nationwide, Population-Based Cohort Study – Circulation (link to abstract – $ for full-text)
Commentaries: Stopping Aspirin Hikes CV risk – Cardiobrief (free) AND Aspirin Discontinuation Tied to Increased Risk for CV Events – Physician’s First Watch (free)
Adherence Tradeoff to Multiple Preventive Therapies and All-Cause Mortality After Acute Myocardial Infarction
24 Sep, 2017 | 21:37h | UTCAdherence Tradeoff to Multiple Preventive Therapies and All-Cause Mortality After Acute Myocardial Infarction – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Study Questions Incremental Benefit of Beta-Blockers After Acute MI – TCTMD (free) AND Beta blockers not needed after heart attack if other medications taken – University of North Carolina at Chapel Hill, via Eurekalert (free) AND Adherence to medications post-MI is below 50%; beta-blockers offer little incremental benefit – Cardiovascular Business (free)
Related study published recently: β-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction – Journal of The American College of Cardiology (free)
Adverse drug reactions of montelukast in children and adults
24 Sep, 2017 | 21:34h | UTCAdverse drug reactions of montelukast in children and adults – Pharmacology Research & Perspectives (free)
Commentaries: Montelukast Tied to Psychiatric Adverse Events in Kids, Adults – Medscape (free registration required) AND Asthma Drug, Montelukast, Tied to Nightmares, Depression – Drugs.com (free)
Meta-analysis: Antidepressants linked to increased risk of death
24 Sep, 2017 | 21:39h | UTCThe Mortality and Myocardial Effects of Antidepressants Are Moderated by Preexisting Cardiovascular Disease: A Meta-Analysis – Psychotherapy and Psychosomatics (link to abstract – $ for full-text)
Commentaries: Antidepressant use associated with higher risk of death – OnMedica (free) AND Antidepressants may raise death risk by a third – Medical News Today (free) AND Antidepressants Tied to a Significantly Increased Risk for Death – Medscape (free registration required) AND Antidepressants Associated with Significantly Elevated Risk of Death, Researchers Find – McMaster University, via NewsWise (free)
Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis
24 Sep, 2017 | 20:18h | UTCEditorial: Romosozumab — Promising or Practice Changing? (free)
Prevention and Control of Seasonal Influenza with Vaccines
24 Sep, 2017 | 20:10h | UTCCommentary: CDC: Updated Influenza Immunization Recommendations for 2017-2018 – MPR (free)
Recommendations for Prevention and Control of Influenza in Children
24 Sep, 2017 | 20:09h | UTCCommentary: 2017-2018 recommendations for pediatric influenza vaccination – Clinical Advisor (free) AND Fall Weather Headed Your Way? Time For Flu Shots – NPR (free)