Pharmacology/Pharmaceutical Industry
Guideline: Insulin therapy for adult patients with type 2 diabetes mellitus
28 Oct, 2017 | 23:30h | UTC
Research: Azithromycin, levofloxacin or rifaximin for travelers diarrhea?
23 Oct, 2017 | 20:45h | UTCTrial Evaluating Ambulatory Therapy of Travelers’ Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide – Clinical Infectious Diseases (link to abstract – $ for full-text)
Commentary: Azithromycin, levofloxacin, rifaximin all effective for travelers diarrhea – Healio (free registration required)
Carefully managed antibiotic use could halve antibiotic-resistant infections
23 Oct, 2017 | 20:38h | UTCCarefully managed antibiotic use could halve antibiotic-resistant infections – NIHR Signal (free)
Original article: Effect of antibiotic stewardship on the incidence of infection and colonisation with antibiotic-resistant bacteria and Clostridium difficile infection: a systematic review and meta-analysis – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Research: Short and Long Term Complications of In Utero Exposure to Lamotrigine
21 Oct, 2017 | 17:39h | UTCNews release: Study Finds Epilepsy Drug to Be Safe During Pregnancy – Wiley (free)
Source: Study finds lamotrigine to be safe during pregnancy – The BMJ Research News ($)
Meta-analysis: Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients
21 Oct, 2017 | 17:32h | UTCAntibiotic-associated diarrhea ocurred in 8.0% of the probiotic group compared to 17.7% in the control group. The number needed to treat (NNT) to prevent one case of diarrhea was 11 (95% CI 6 to 13).
Last Month in Oncology with Dr. Bishal Gyawali: September 2017
17 Oct, 2017 | 19:10h | UTCLast Month in Oncology with Dr. Bishal Gyawali: September 2017 – eCancer News (free)
Research: Iron absorption from oral iron supplements given on consecutive versus alternate days
17 Oct, 2017 | 19:10h | UTCCommentaries: Treatment of iron deficiency is getting trendy – The Lancet Haematology (free) AND Taking Iron Every Other Day Linked to Better Absorption in Iron-Deficient Women – Physician’s First Watch (free)
Guidelines on perioperative medication in adult cardiac surgery
17 Oct, 2017 | 19:01h | UTCSource: Critical Care Reviews Newsletter (free)
Systematic review: Testing blood procalcitonin levels to decide when to start and stop antibiotics in adults with acute respiratory tract infections
17 Oct, 2017 | 19:00h | UTCOriginal Article: Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections – Cochrane Library (link to abstract – $ for full-text)
“the use of procalcitonin to guide initiation and duration of antibiotic treatment results in lower risks of mortality, lower antibiotic consumption, and lower risk for antibiotic-related side effects”.
Systematic Review: Blood pressure targets in people with cardiovascular disease
17 Oct, 2017 | 18:59h | UTCBlood pressure targets in people with cardiovascular disease – Cochrane Library (free)
We may soon have our first $1 million drug. Who will pay for it? And how?
17 Oct, 2017 | 18:28h | UTCWe may soon have our first $1 million drug. Who will pay for it? And how? – STAT (free)
Research: Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus
17 Oct, 2017 | 18:31h | UTCCommentaries: Proton pump inhibitors linked to liver disease, researchers find – The Pharmaceutical Journal (free) AND Liver disease risk may be heightened by gastric acid drugs – Medical News Today (free) AND Common acid reflux medications promote chronic liver disease – EurekAlert (free)
Review: Why and how to step down chronic asthma drugs
17 Oct, 2017 | 18:25h | UTCState of The Art Review: Why and how to step down chronic asthma drugs – The BMJ (free)
Research: Association of Antidepressant Medications With Incident Type 2 Diabetes in Youths
17 Oct, 2017 | 18:24h | UTCAssociation of Antidepressant Medications With Incident Type 2 Diabetes Among Medicaid-Insured Youths – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: Antidepressant Use in Youth Tied to Increased Diabetes Risk – Physician’s First Watch (free)
Related study: The risk of new-onset diabetes in antidepressant users – A systematic review and meta-analysis – PLOS One (free) AND Commentary: Type 2 Diabetes and Antidepressant Drug Use: Is There a Causal Link? – Endocrinology Advisor (free)
Review: Calcium and Cardiovascular Disease
17 Oct, 2017 | 18:00h | UTCCalcium and Cardiovascular Disease – Endocrinology and Metabolism (free)
Review: Recent Updates of the Diagnosis and Prevention of Venous Thromboembolism in Patients with a Hip Fracture
17 Oct, 2017 | 17:58h | UTC
Individual support of nurses using electronic medicine monitors can improve HIV treatment
17 Oct, 2017 | 17:51h | UTCIndividual support of nurses using electronic medicine monitors can improve HIV treatment – NIHR Signal (free)
Original article: Effectiveness and cost-effectiveness of a nurse-delivered intervention to improve adherence to treatment for HIV: a pragmatic, multicentre, open-label, randomised clinical trial – The Lancet Infectious Diseases (free)
Revised Recommendations for the Use of Hormonal Contraception Among Women at High Risk for HIV Infection
17 Oct, 2017 | 17:44h | UTC
Review: Angiogenesis Inhibitors in NSCLC
17 Oct, 2017 | 17:42h | UTCAngiogenesis Inhibitors in NSCLC – International Journal of Molecular Sciences (free)
Review: Pharmacotherapy for idiopathic pulmonary fibrosis
17 Oct, 2017 | 17:40h | UTC
Research: Insulin Pump vs Insulin Injection in Young Adults With Type 1 Diabetes
12 Oct, 2017 | 18:41h | UTCAssociation of Insulin Pump Therapy vs Insulin Injection Therapy With Severe Hypoglycemia, Ketoacidosis, and Glycemic Control Among Children, Adolescents, and Young Adults With Type 1 Diabetes – JAMA (link to abstract – $ for full-text)
Commentaries: Insulin Pumps Associated With Lower Risk of Serious Complications among Young Patients with Type 1 Diabetes – The JAMA Network (free) AND Insulin-Pump Use Benefits Young People With Type 1 Diabetes – Medscape (free registration required) AND Can insulin pumps work better than injections for kids with diabetes? – Reuters (free)
Research: Gabapentin, opioids, and the risk of opioid-related death
12 Oct, 2017 | 18:32h | UTCCommentaries: Gabapentin, Opioid Combo May Up the Risk of Opioid-Related Death – MPR (free) AND Gabapentin Plus Opioids a Deadly Combination? – MPR (free)
Research: morphine versus ibuprofen for postoperative orthopedic pain in children
12 Oct, 2017 | 18:31h | UTCCommentaries: Ibuprofen Better Than Morphine After Minor Surgery in Kids – Medscape (free registration required) AND Ibuprofen better choice over oral morphine for pain relief in children after minor surgery – MedicalXpress (free)
As Cancer Tears Through Africa, Drug Makers Draw Up a Battle Plan
12 Oct, 2017 | 18:22h | UTCAs Cancer Tears Through Africa, Drug Makers Draw Up a Battle Plan – The New York Times (10 articles per month are free)
“In a deal similar to the one that turned the tide against AIDS, manufacturers and charities will make chemotherapy drugs available in six poor countries at steep discounts”.
Research: Discontinuing Inappropriate Medication Use in Nursing Home Residents
12 Oct, 2017 | 18:18h | UTCDiscontinuing Inappropriate Medication Use in Nursing Home Residents: A Cluster Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Deprescribing Intervention Improves Nursing Home Care – Medscape (free registration required) AND Multistep tool is effective for discontinuing inappropriate medication use in the nursing home setting – MedicalXpress (free)