Pharmacology/Pharmaceutical Industry
Hydroxychloroquine and Coronavirus: A Guide to the Scientific Studies so Far
24 Apr, 2020 | 03:28h | UTCHydroxychloroquine and coronavirus: a guide to the scientific studies so far – The Guardian
Opinion: A Call for Rational Intensive Care in the Era of COVID-19
23 Apr, 2020 | 09:34h | UTC
Editorial: Remdesivir in Covid-19
23 Apr, 2020 | 09:35h | UTCRemdesivir in covid-19 – The BMJ
Related: What’s Happening With Remdesivir? – Science Translational Medicine AND Slow down your giddyup on Gilead news – Health News Review
Cochrane Review Confirms Effectiveness and Safety of MMR vaccines
23 Apr, 2020 | 09:24h | UTCVaccines for measles, mumps, rubella, and varicella in children – Cochrane Library
News Release: Cochrane Review confirms effectiveness of MMR vaccines – Cochrane Library
[Abstract Only] Randomized Trial: Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease
23 Apr, 2020 | 09:14h | UTC
[Preprint] Observational Study: No Benefit from Hydroxychloroquine in Patients Hospitalized with Covid-19
22 Apr, 2020 | 08:58h | UTCOutcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19 – medRxiv
Commentaries: Study finds no benefit, higher death rate in patients taking hydroxychloroquine for Covid-19 – CNN AND More deaths, no benefit from malaria drug in VA virus study – Associated Press
What’s Happening with Remdesivir?
20 Apr, 2020 | 00:12h | UTCWhat’s Happening With Remdesivir? – Science Translational Medicine
See also: Slow down your giddyup on Gilead news – Health News Review
Observational Study: Inpatient Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers Seems Safe Among Patients with Hypertension Hospitalized With COVID-19
20 Apr, 2020 | 00:01h | UTC
Systematic Review: Prophylactic Role of Chloroquine and Hydroxychloroquine in COVID‐19
19 Apr, 2020 | 23:57h | UTC
COVID-19 and Renin Angiotensin Blockers: Current Evidence and Recommendations
20 Apr, 2020 | 00:00h | UTCCOVID-19 and Renin Angiotensin Blockers: Current Evidence and Recommendations – Circulation
Commentary: COVID-19 and Renin Angiotensin Blockers – American College of Cardiology
Study Commentary: Hydroxychloroquine Fails First Meaningful RCT
17 Apr, 2020 | 02:25h | UTCHydroxychloroquine fails first meaningful RCT – PulmCrit
Original Study: Hydroxychloroquine for Covid-19: No Benefit in New Open-label, Randomized Trial
Related Commentary: Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base – The Lancet Respiratory Medicine
Hydroxychloroquine for Covid-19: No Benefit in New Open-label, Randomized Trial
15 Apr, 2020 | 03:42h | UTC[Preprint] Hydroxychloroquine in patients with COVID-19: an open-label, randomized, controlled trial – medRxiv
See also just published observational study (Preprint): No evidence of clinical efficacy of hydroxychloroquine in patients hospitalized for COVID-19 infection with oxygen requirement: results of a study using routinely collected data to emulate a target trial – medRxiv
Related Commentary on Twitter
#COVID19 Here comes another dataset of #Hydroxychloroquine from an open-label randomized controlled trial in Chinahttps://t.co/qW93wMDILK
No difference in 28-day #coronavirus negative conversion rate for HCQ + SOC vs SOC
No difference in 28-day symptoms alleviation rate either pic.twitter.com/pOsBSQWeuO
— Andy Biotech (@AndyBiotech) April 14, 2020
Review: Pharmacologic Treatments for COVID-19
14 Apr, 2020 | 03:05h | UTCPharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review – JAMA
Compassionate Use of Remdesivir for Patients with Severe Covid-19
13 Apr, 2020 | 00:23h | UTCCompassionate Use of Remdesivir for Patients with Severe Covid-19 – New England Journal of Medicine
Commentaries: PulmCrit – Eleven reasons the NEJM paper on remdesivir reveals nothing AND Expert reaction to a study about compassionate use of remdesivir for patients with severe COVID-19 – Science Media Centre AND What Do the New Remdesivir Data Mean? – Science Translational Medicine
Implementation Guide: Optimizing Medication Management during the COVID-19 Pandemic
13 Apr, 2020 | 00:18h | UTC
Related Commentary on Twitter
Task force recommendations about managing meds in post-acute and long-term care during COVID-19. https://t.co/yoU76suVYo
Summary of recommendations in thread below:
— Mike Steinman (@MikeSteinman) April 10, 2020
Review: Should Chloroquine and Hydroxychloroquine be Used to Treat COVID-19?
10 Apr, 2020 | 02:50h | UTCShould chloroquine and hydroxychloroquine be used to treat COVID-19? A rapid review – BJGP Open
“At present, there is insufficient evidence to determine whether CQ/HCQ are safe and effective treatments for COVID-19”
Editorial: Chloroquine and Hydroxychloroquine in Covid-19
9 Apr, 2020 | 03:47h | UTCChloroquine and hydroxychloroquine in covid-19 – Tue BMJ
“Use of these drugs is premature and potentially harmful.”
Safety Considerations with Chloroquine, Hydroxychloroquine and Azithromycin in the Management of SARS-CoV-2 Infection
9 Apr, 2020 | 03:42h | UTC
COVID-19: More Opinions on Hydroxychloroquine
7 Apr, 2020 | 04:17h | UTCHydroxychloroquine Update For April 6 – Science Translational Medicine
The Debacle of Hydroxychloroquine and Azithromycin for COVID19 – Dr. John M.
Summary: wait for proper studies before prescribing.
Study: No Benefit from Hydroxychloroquine and Azithromycin in Patients with Severe COVID-19 Infection
6 Apr, 2020 | 01:46h | UTC
In Vitro Study: Ivermectin Inhibits Replication of SARS-CoV-2
6 Apr, 2020 | 01:49h | UTCCommentary: Possible coronavirus drug identified by Australian scientists – Monash University
Opioids in Older Adults: Indications, Prescribing, Complications, and Alternative Therapies for Primary Care
3 Apr, 2020 | 03:52h | UTC
Use of Hydroxychloroquine and Chloroquine During the COVID-19 Pandemic: What Every Clinician Should Know
2 Apr, 2020 | 04:21h | UTC
New WHO Guide to Help Countries Expand Access to Essential Medicines
2 Apr, 2020 | 03:59h | UTCSelection of essential medicines at country level – World Health Organization
News Release: New WHO Guide to help countries expand access to essential medicines – World Health Organization
‘Panic Prescribing’ Untested Coronavirus Treatments
1 Apr, 2020 | 05:51h | UTC- ‘Panic Prescribing’ Untested Coronavirus Treatments: A Danger To Patients Today and Tomorrow – Health Affairs
- We shouldn’t rush to use an unproven malaria drug to treat the coronavirus – STAT
- See also: Twitter Thread on the Latest Study Testing Hydroxychloroquine, by Lucas Morin