Pediatrics – Psychiatry
Cohort Study | In utero exposure to ADHD medication does not seem to result in worse offspring neurodevelopmental outcomes
14 Feb, 2023 | 10:54h | UTCSummary: The authors conducted a study to investigate the long-term effects of in utero exposure to ADHD medication (methylphenidate, amphetamine, dexamphetamine, lisdexamphetamine, modafinil, atomoxetine, clonidine) on offspring. The study followed 1,068,073 liveborn singletons from 1998 to 2018 and compared the outcomes of children whose mothers continued or discontinued ADHD medication during pregnancy. The main outcomes were neurodevelopmental psychiatric disorders, impairments in vision or hearing, epilepsy, seizures, or growth impairment during childhood or adolescence. After adjustment for demographic and psychiatric characteristics of the mother, no increased risk of any developmental disorders was found in offspring exposed to ADHD medication compared to those not exposed. The results provide reassurance for women with ADHD who depend on medication and consider continuing it during pregnancy.
(By ChatGPT, reviewed and edited)
Article: In utero exposure to ADHD medication and long-term offspring outcomes – Molecular Psychiatry (link to abstract – $ for full-text)
Commentary from the author on Twitter (thread – click for more)
In-utero exposure to ADHD medication is not associated with long-term adverse neurodevelopmental disorders and growth restriction in the offspring.
Read the thread below ?on our new paper just published in @molpsychiatry
? https://t.co/MKZ0aeFnhU#ADHD— Kathrine Bang Madsen (@Kathrine_BaMa) February 9, 2023
M-A | Efficacy of treatments for children, adolescents, and young adults with Tourette’s syndrome
8 Feb, 2023 | 12:13h | UTCComparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette’s syndrome: a systematic review and network meta-analysis – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)
Commentary on Twitter
Treatment recommendations are inconsistent for #Tourette syndrome.
New network meta-analysis by @luis_farhat & team shows that #antipsychotics are the most efficacious, while α-2 agonists are also more efficacious than placebohttps://t.co/awYHWUJA3v
— The Lancet Child & Adolescent Health (@LancetChildAdol) December 19, 2022
Cohort Study | Associations between infant screen use, electroencephalography markers, and cognitive outcomes
1 Feb, 2023 | 13:34h | UTCCommentaries:
Infant Screen Use Linked to Alterations in Cortical EEG Before Age 2 – HealthDay
Your child’s academic success may start with their screen time as infants, study says – CNN
M-A | Association between autism spectrum disorders and cardiometabolic diseases
1 Feb, 2023 | 13:11h | UTCAssociation Between Autism Spectrum Disorders and Cardiometabolic Diseases: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)
Editorial: Autism, Physical Health Conditions, and a Need for Reform – JAMA Pediatrics (free for a limited period)
Commentary on Twitter
Study results suggest that having autism may be associated with a higher risk of developing diabetes, dyslipidemia, and heart disease. https://t.co/T19VAQxdjf
— JAMA Pediatrics (@JAMAPediatrics) January 30, 2023
Cohort Study | Alcohol-related problems before and after metabolic and bariatric surgery in adolescents
26 Jan, 2023 | 12:01h | UTCA Prospective Cohort of Alcohol use and Alcohol-related Problems Before and After Metabolic and Bariatric Surgery in Adolescents – Annals of Surgery (link to abstract – $ for full-text)
News Release: Problems with Alcohol Increase After Weight-Loss Surgery in Adolescence – Ann & Robert H. Lurie Children’s Hospital of Chicago
Related Study: Association Between Bariatric Surgery and Alcohol Use–Related Hospitalization and All-Cause Mortality in a Veterans Affairs Cohort – JAMA Surgery (link to abstract – $ for full-text)
Review | Common sleep disorders in children
24 Jan, 2023 | 14:22h | UTCCommon Sleep Disorders in Children – American Family Physician
Note: AFP provides superb review articles that are freely available one year after publication.
RCT | Telehealth treatment of behavior problems in young children with developmental delay
20 Jan, 2023 | 14:38h | UTCTelehealth Treatment of Behavior Problems in Young Children With Developmental Delay: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries:
Telehealth Parent-Child Interaction Therapy Aids Child Behavior – HealthDay
Commentary on Twitter
Study provides evidence that a #telehealth-delivered parenting intervention with real-time therapist coaching led to significant and maintained improvements for young children with #DevelopmentalDelay and their caregivers. https://t.co/xYOOxDfL4U
— JAMA Pediatrics (@JAMAPediatrics) January 10, 2023
Gestational age at birth and cognitive outcomes in adolescence: population based full sibling cohort study
19 Jan, 2023 | 14:27h | UTCEditorial: Gestational age at birth and school performance – The BMJ
News Release: Premature birth linked to poorer school grades in adolescence – BMJ
State of the Art Review | Telemental health for clinical assessment and treatment
17 Jan, 2023 | 13:29h | UTCTelemental health for clinical assessment and treatment – The BMJ
Commentary on Twitter
Telemental health use increased substantially and globally during the pandemic, however, the prevalence of its use has varied widely.
What do we know about the efficacy of telemental health for treatment and what do guidelines say on best practice?https://t.co/AqHKMkKNIV
— The BMJ (@bmj_latest) January 16, 2023
Cohort Study | Trends in antipsychotic prescribing to children and adolescents in England
15 Jan, 2023 | 20:26h | UTCNews Release: Researchers reveal worrying rise in antipsychotic prescriptions for children and young people – University of Manchester
Commentary on Twitter
"From 2000 to 2019, the prescriptions for antipsychotics for children and adolescents in England doubled from an annual period prevalence in 2000 of 0·057% (95% CI 0·052–0·063%) to 0·105% (0·100–0·111%) in 2019"
New research Article @FBMH_UoM @GMMH_NHS https://t.co/ukXkSVfhtI
— The Lancet Psychiatry (@TheLancetPsych) January 11, 2023
RCT | Ecopipam for Tourette Syndrome
15 Jan, 2023 | 20:09h | UTCEcopipam for Tourette Syndrome: A Randomized Trial – Pediatrics
Commentary: Ecopipam May Reduce Tics in Children With Tourette Syndrome – Psychiatric News Alert
Commentary on Twitter
Ecopipam, a selective D1-like receptor antagonist, is in development for children & adolescents with Tourette syndrome. Can ecopipam achieve a clinically meaningful reduction in tics without the disadvantages of D2-like receptor antagonists? https://t.co/GXxnPsP74C #Pediatrics pic.twitter.com/14fwu4npJi
— AAP Pediatrics (@aap_peds) January 11, 2023
Review | Autism spectrum disorder
11 Jan, 2023 | 14:31h | UTCAutism Spectrum Disorder: A Review – JAMA (free for a limited period)
M-A | The effectiveness of gaming interventions for depression and anxiety in young people
11 Jan, 2023 | 13:52h | UTCCommentary: Can gaming interventions help treat youth depression or anxiety? – The Mental Elf
Cohort Study | Association of habitual checking behaviors on social media with longitudinal functional brain development
9 Jan, 2023 | 14:38h | UTCAssociation of Habitual Checking Behaviors on Social Media With Longitudinal Functional Brain Development – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries:
Social Media Checking Behaviors in Teens Linked to Brain Changes – HealthDay
For adolescents, social media might be a brain-changer, researchers say – CNN
M-A | Physical activity interventions to alleviate depressive symptoms in children and adolescents
9 Jan, 2023 | 14:37h | UTCPhysical Activity Interventions to Alleviate Depressive Symptoms in Children and Adolescents: A Systematic Review and Meta-analysis – JAMA Pediatrics (link to abstract – $ for full-text)
Commentary: Exercise, Sports: A Natural Antidepressant for Teens – HealthDay
Commentary on Twitter
The results of this systematic review and meta-analysis suggest that physical activity interventions can alleviate symptoms of depression in children and adolescents. https://t.co/7P6gWPf35K
— JAMA Pediatrics (@JAMAPediatrics) January 3, 2023
Another study suggests youngest in class are being overmedicated for ADHD.
9 Dec, 2022 | 13:35h | UTCRelative Age and Psychotropic Drug Use in Preterm and Term-Born Children and Young Adults – Pediatrics (link to abstract – $ for full-text)
Commentary: Are the youngest children in class overmedicated? – Norwegian SciTech News
Related:
Study: Youngest in Class More Likely to be Diagnosed with ADHD
Systematic Review: Youngest in Class More Likely to be Diagnosed with ADHD
Guideline | Psychological care of children, adolescents and young adults with diabetes.
6 Dec, 2022 | 13:53h | UTC
M-A | The role of metformin on weight gain associated with atypical antipsychotics in children and adolescents.
6 Dec, 2022 | 13:32h | UTC
New WHO report showcases strategies to keep children safe online.
5 Dec, 2022 | 00:24h | UTCNews Release: New report showcases strategies to keep children safe online – World Health Organization
Report: What works to prevent violence against children online? – World Health Organization
Commentary on Twitter (thread – click for more)
? report by WHO on what works to prevent online violence against children, addressing the growing worldwide concern of keeping children safe online
? https://t.co/pDL1l2TKkT pic.twitter.com/uPCJoiIblK
— World Health Organization (WHO) (@WHO) December 2, 2022
RCT | One-session treatment compared with multisession CBT in children aged 7-16 years with specific phobias.
27 Nov, 2022 | 22:07h | UTC
Commentary on Twitter
One-session treatment and cognitive–behavioural therapy worked just as well as multisession cognitive–behavioural therapy for treating phobias in children and young people. It's also highly likely to be cost-saving.
Read the full report: https://t.co/i7M58yGfLv pic.twitter.com/ZEGgG4yh26
— NIHR Evidence (@NIHRevidence) November 25, 2022
Post-trial follow-up | A brief intervention to prevent alcohol use can have sustained effects among high-risk adolescents.
22 Nov, 2022 | 13:08h | UTC
Commentary on Twitter
RCT: Personality-targeted school-based prevention program “Preventure” can effectively reduce alcohol-related harms up to 7 years later, showing the meaningful & sustained benefits of school-based prevention programs. @theMatilda_USyd https://t.co/HuoZZluc6I #OAResearch
— JAMA Network Open (@JAMANetworkOpen) November 17, 2022
Cohort Study | Associations between childhood trauma and childhood psychiatric disorders in Brazil.
9 Nov, 2022 | 12:15h | UTCCommentary: Birth cohort study reveals the mental health burden of trauma in childhood – University of Bath
RCT | Efficacy and safety of methylphenidate and behavioral parent training for children aged 3–5 years with ADHD.
9 Nov, 2022 | 12:09h | UTCEfficacy and safety of methylphenidate and behavioural parent training for children aged 3–5 years with attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled, and sham behavioural parent training-controlled trial – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
Methylphenidate was effective in reducing #ADHD symptoms and improving functionality, and behavioural parent training was effective in improving functionality for preschool children with ADHD after 8 weeks of treatment.
New RCT by @gvpolanczyk & team: https://t.co/iDUhRMTno4
— The Lancet Child & Adolescent Health (@LancetChildAdol) October 26, 2022
M-A | Migraine is linked to an increased risk of anxiety and depressive symptoms in children and adolescents.
4 Nov, 2022 | 13:20h | UTCAnxiety and Depressive Symptoms and Disorders in Children and Adolescents With Migraine: A Systematic Review and Meta-analysis – JAMA Pediatrics (Free for a limited period)
Editorial: Migraine and Mental Health in Pediatrics – Pediatrics (free for a limited period)
Commentary: Youth With Migraines Twice as Likely to Have Anxiety, Depression – Psychiatric News Alert
Cohort Study | Association of attention-deficit/hyperactivity disorder diagnosis with adolescent quality of life.
18 Oct, 2022 | 12:48h | UTC
Commentary on Twitter
Adolescents with an ADHD diagnosis reported similar quality of life overall and on 3 subdomains but worse outcomes for 5 other aspects of quality of life compared adolescents with similar levels of hyperactive/inattentive behaviors but no ADHD diagnosis. https://t.co/5o0MNfEzjD
— JAMA Network Open (@JAMANetworkOpen) October 13, 2022