Pediatrics – Infectious Diseases
Pro-Con Debate | Should we delay covid-19 vaccination in children?
13 Jul, 2021 | 09:51h | UTCShould we delay covid-19 vaccination in children? – The BMJ
News release: Should we delay COVID-19 vaccination in children? – British Medical Journal
Commentary on Twitter
Covid-19 vaccines in adults have been remarkably effective. There is good reason to expect that the same will be true in children.
A group of authors discuss the pros and cons of vaccinating children against covid-19 https://t.co/TOEI67YPeH
— The BMJ (@bmj_latest) July 9, 2021
New CDC Guidance for COVID-19 prevention in kindergarten schools says safely returning to in-person instruction is a priority.
12 Jul, 2021 | 03:11h | UTCCommentaries: Updated CDC schools guidance prioritizes in-person learning, even if all Covid-19 safety measures aren’t in place – CNN AND The C.D.C. Issues New School Guidance, With Emphasis on Full Reopening – The New York Times AND New CDC guidance says fully vaccinated teachers and students don’t need to wear masks indoors – CNBC AND CDC calls for reopening schools fully, recommends masking – CIDRAP
Related: COVID and schools: the evidence for reopening safely – Nature
[Preprint] Study confirms children’s extremely low risk of death from Covid-19 – “99·995% of children and young people with a positive SARS-CoV-2 test survived”.
12 Jul, 2021 | 03:12h | UTCCommentaries: Risks of severe illness in children from COVID-19 shown to be very low in largest study yet – University of Liverpool AND Covid: Children’s extremely low risk confirmed by study – BBC
Related study from the same group (preprint): Risk factors for intensive care admission and death amongst children and young people admitted to hospital with COVID-19 and PIMS-TS in England during the first pandemic year – medRxiv
CDC: Use of mRNA COVID-19 vaccine after reports of myocarditis among vaccine recipients – “Continued use of mRNA COVID-19 vaccines in all recommended age groups will prevent morbidity and mortality from COVID-19 that far exceed the number of cases of myocarditis expected”.
9 Jul, 2021 | 10:17h | UTC
Commentary on Twitter
In a new @CDCMMWR, the Advisory Committee on Immunization Practices recommends everyone 12 & older get a #COVID19 vaccine. The benefits of vaccination in preventing illness & death outweigh the rare risk of heart inflammation after vaccination. More: https://t.co/iPjbhU5jeV. pic.twitter.com/IggrZ4DX7L
— CDC (@CDCgov) July 6, 2021
Schooling during COVID-19: Recommendations from the European Technical Advisory Group for schooling during COVID-19.
8 Jul, 2021 | 09:11h | UTC
COVID and schools: the evidence for reopening safely.
8 Jul, 2021 | 09:12h | UTCCOVID and schools: the evidence for reopening safely – Nature
Study Commentary: Decreased Antibiotic Use for Acute Otitis Media and Acute Sinusitis Following Implementation of Childhood PCV13 Immunization.
8 Jul, 2021 | 08:54h | UTC
Opinion | Covid is a greater risk to young people than the vaccines.
5 Jul, 2021 | 02:34h | UTCCovid Is a Greater Risk to Young People Than the Vaccines – The New York Times
Counterpoint: Weighing myocarditis cases, ACIP failed to balance the harms vs benefits of 2nd doses – by Wesley Pegden AND Vaccine-Induced Myocarditis Concerns Demand Respect, Not Absolutism – Medscape (free registration required)
Commentary on Twitter
“Realize the choice is not ‘vaccinate or do nothing.’ It’s ‘vaccinate or eventually contract the coronavirus,’ and the risks that come with it.”
My latest with @celinegounder and @EMDocinTraining@NYTOpinion @acsifferlin https://t.co/wGugCuWgSs
— Jeremy Faust MD MS (ER physician) (@jeremyfaust) July 4, 2021
Patient page: return to play after COVID-19 infection in children
2 Jul, 2021 | 11:21h | UTCReturn to Play After COVID-19 Infection in Children – JAMA Pediatrics
Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years.
29 Jun, 2021 | 10:09h | UTCInvited commentary: COVID-19 vaccines for children younger than 12 years: are we ready? – The Lancet Infectious Diseases
Commentary on Twitter
NEW—A phase 1/2 clinical trial of #CoronaVac in 550 children and adolescents aged 3-17 years in China suggests two doses of the vaccine are safe and generate a strong antibody response. Read in @TheLancetInfDis: https://t.co/eXSagRu1Cs pic.twitter.com/fOKNLUjNwc
— The Lancet (@TheLancet) June 28, 2021
CDC: mRNA vaccines are likely linked to cases of myocarditis and pericarditis – 1,226 cases of myocarditis or pericarditis have been reported mostly in people under 30.
24 Jun, 2021 | 09:51h | UTCSee also: Experts: mRNA COVID-19 vaccines likely tied to heart inflammation – CIDRAP
Related: Case series: 7 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: clinical and cardiac magnetic resonance imaging findings of 4 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: symptomatic acute myocarditis in 7 adolescents following mRNA COVID-19 vaccination. AND CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.
Audio Interview: potential treatments for children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19.
18 Jun, 2021 | 08:33h | UTCAudio Interview: Covid-19 in Children – New England Journal of Medicine
Symptomatic fever management in children: A systematic review of national and international guidelines.
21 Jun, 2021 | 08:28h | UTC
Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.
18 Jun, 2021 | 08:35h | UTCEditorial: Immunotherapy for MIS-C — IVIG, Glucocorticoids, and Biologics
Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.
18 Jun, 2021 | 08:36h | UTCTreatment of Multisystem Inflammatory Syndrome in Children – New England Journal of Medicine
Editorial: Immunotherapy for MIS-C — IVIG, Glucocorticoids, and Biologics
Commentaries: Steroids may be effective treatment for COVID-19 complications in children – Imperial College London AND Expert reaction to study looking at treatments for COVID-19 complications in children – Science Media Centre
Case series: clinical and cardiac magnetic resonance imaging findings of 4 cases of myocarditis following mRNA-based COVID-19 vaccination.
17 Jun, 2021 | 09:43h | UTCCommentary: Possible Association Between COVID-19 Vaccine and Myocarditis – American College of Cardiology
Related: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.
Case series: 7 cases of myocarditis following mRNA-based COVID-19 vaccination.
17 Jun, 2021 | 09:45h | UTCMyocarditis after BNT162b2 and mRNA-1273 Vaccination – Circulation
Related: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.
Case series: symptomatic acute myocarditis in 7 adolescents following mRNA COVID-19 vaccination.
17 Jun, 2021 | 09:41h | UTCRelated: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.
Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.
14 Jun, 2021 | 08:48h | UTCCommentary: MIS-C Incidence 316 Persons Per 1 Million SARS-CoV-2 Infections – HealthDay
Commentary on Twitter
About 1 in every 3,000 children who got COVID ended up with MIS-C. MIS-C incidence among Black persons and Hispanic or Latino persons was approximately 9x higher, and incidence among Asian or Pacific Islander persons was approximately 3x higher https://t.co/JTEsvgvFcz
— Daniel Griffin MD PhD (@DanielGriffinMD) June 12, 2021
Children with symptomatic SARS-CoV-2 infection have similar viral loads and may be as contagious as symptomatic adults.
14 Jun, 2021 | 08:49h | UTCEditorial: Implications of SARS-CoV-2 Viral Load in Children: Getting Back to School and Normal
Commentary on Twitter (thread – click for more)
In a new study in @JAMAPediatrics, we compared symptoms and viral load in children and adults with SARS-CoV-2. Those with symptoms had higher virus loads than those without. Importantly, within these groups – viral load was the same in children and adults. https://t.co/UgaFzvMNlg pic.twitter.com/cjpt2yqQ3R
— Helen Chu (@HelenChuMD) June 11, 2021
CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare.
11 Jun, 2021 | 08:28h | UTCSee also: CDC plans “emergency meeting” on rare heart inflammation following COVID-19 vaccines – CBC News
Related: Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men.
China to offer COVID-19 vaccine to children as young as three.
9 Jun, 2021 | 08:26h | UTCChina to offer COVID-19 vaccine to children as young as three – MedicalXpress
See also: Sinovac says its vaccine is safe for children as young as 3 – Associated Press
In youth, COVID-19 causes more complications than flu; fatality is rare.
9 Jun, 2021 | 08:23h | UTCOriginal study: 30-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – Pediatrics
Underlying medical conditions associated with severe COVID-19 illness among children – the strongest risk factors for hospitalization were chronic and complex chronic diseases, type 1 diabetes, and obesity.
8 Jun, 2021 | 09:37h | UTCCommentaries: Underlying illness, respiratory infection raise risk for severe COVID in kids – CIDRAP AND COVID-19 in Children—Not Just Little Adults – JAMA Network Open
Commentary on Twitter
This cross-sectional study found a higher risk of severe #COVID19 illness among children with medical complexity and certain underlying conditions, such as type 1 diabetes, cardiac and circulatory congenital anomalies, and obesity. https://t.co/ifq1Ao0HKS
— JAMA Network Open (@JAMANetworkOpen) June 7, 2021
WHO: Vaccinating kids ‘not a high priority’ amid shortage
4 Jun, 2021 | 10:31h | UTCWHO: Vaccinating kids ‘not a high priority’ amid shortage – Associated Press
Related: WHO: Wealthy nations urged to delay youth Covid vaccines, donate to solidarity scheme AND Editorial: Vaccinating children against SARS-CoV-2 – “Hard to justify right now for most children in most countries”. AND Opinion | American Kids Can Wait – “The U.S. should delay shots for children until global vaccine-manufacturing capacity significantly expands and the crisis in India subsides”. AND Vaccinating children before poor morally wrong, Oxford scientist says – BBC