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Pediatrics (all articles)

Rationale and approach to evaluating interventions to promote child health in LMICs.

10 May, 2022 | 10:24h | UTC

Rationale and Approach to Evaluating Interventions to Promote Child Health in LMICs – Pediatrics

 

Diagnostic stewardship tied to fewer blood cultures, antibiotics in sick kids.

9 May, 2022 | 01:23h | UTC

Commentary: Diagnostic stewardship tied to fewer blood cultures, antibiotics in sick kids – CIDRAP

Original Study: Association of Diagnostic Stewardship for Blood Cultures in Critically Ill Children With Culture Rates, Antibiotic Use, and Patient Outcomes: Results of the Bright STAR Collaborative – JAMA Peditrics

News Release: Hospitals can reduce antibiotic overuse by avoiding unnecessary blood draws in critically ill children, study shows – Johns Hopkins University School of Medicine

 

Commentary on Twitter

 

Podcast: Appendicitis Pearls.

9 May, 2022 | 01:15h | UTC

#49: Appendicitis – Tips and Tricks For When It’s the Appendix – The Cribsiders

 

Systematic Review: Interventions to promote physical activity and healthy digital media use in children and adolescents.

9 May, 2022 | 01:10h | UTC

Interventions to Promote Physical Activity and Healthy Digital Media Use in Children and Adolescents: A Systematic Review – Pediatrics

 

Systematic Review: Preventing unintentional injuries in school-aged children.

9 May, 2022 | 01:13h | UTC

Preventing Unintentional Injuries in School-Aged Children: A Systematic Review – Pediatrics

 

M-A: Interventions for high-burden infectious diseases in children and adolescents.

9 May, 2022 | 01:12h | UTC

Interventions for High-Burden Infectious Diseases in Children and Adolescents: A Meta-analysis – Pediatrics

 

Systematic Review: Delivery strategies supporting school-age child health.

9 May, 2022 | 01:07h | UTC

Delivery Strategies Supporting School-Age Child Health: A Systematic Review – Pediatrics

 

Interventions for health and well-being in school-aged children and adolescents: a way forward.

9 May, 2022 | 01:09h | UTC

Interventions for Health and Well-Being in School-Aged Children and Adolescents: A Way Forward – Pediatrics

 

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids.

5 May, 2022 | 10:59h | UTC

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Related:

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 

The role of sugar-sweetened beverages in the global epidemics of obesity and chronic diseases.

5 May, 2022 | 09:57h | UTC

The role of sugar-sweetened beverages in the global epidemics of obesity and chronic diseases – Nature Reviews Endocrinology (if the link is paywalled, try this one)

 

Review: Current status and future directions of neuromonitoring with emerging technologies in neonatal care.

5 May, 2022 | 09:47h | UTC

Current Status and Future Directions of Neuromonitoring With Emerging Technologies in Neonatal Care – Frontiers in Pediatrics

 

M-A: Efficacy and safety of Selumetinib in pediatric patients with Neurofibromatosis Type 1.

5 May, 2022 | 09:41h | UTC

Efficacy and Safety of Selumetinib in Pediatric Patients With Neurofibromatosis Type 1: A Systematic Review and Meta-analysis  – Neurology (link to abstract – $ for full-text)

Commentary: Selumetinib Significantly Decreased Tumor Burden in Children with Symptomatic Inoperable Plexiform Neurofibromas – Neurology Today

 

Commentary on Twitter

 

M-A: Interventions to prevent bronchopulmonary dysplasia in preterm neonates.

5 May, 2022 | 09:44h | UTC

Interventions to Prevent Bronchopulmonary Dysplasia in Preterm Neonates: An Umbrella Review of Systematic Reviews and Meta-analyses – JAMA Pediatrics (link to abstract – $ for full-text)

Related:

RCT: In preterm infants with respiratory distress syndrome, surfactant administration via a thin catheter did not improve outcomes.

Systematic Review: Late (after 6 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants.

Systematic Review: Early (started within six days) systemic postnatal corticosteroids for preventing bronchopulmonary dysplasia in preterm infants.

State of the Art Review: Diagnosis and management of bronchopulmonary dysplasia.

Systematic Review: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome is associated with reduced risk of death or bronchopulmonary dysplasia, less intubation in the first 72 hours, and reduced incidence of major complications and in‐hospital mortality.

ERS Guideline on Long-term Management of Children with Bronchopulmonary Dysplasia

Randomized Trial: Sustained Inflations vs Intermittent Positive Pressure Ventilation in Extremely Preterm Infants

Randomized Trial: Effect of Hydrocortisone on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation

Research: Long-Term Effects of Inhaled Budesonide for Bronchopulmonary Dysplasia

 

Commentary on Twitter

 

Preventing asthma deaths in school children: 3 things to know.

4 May, 2022 | 10:59h | UTC

Preventing asthma deaths in school children: 3 things to know – Evidently Cochrane

Related video: Preventable

 

Commentary on Twitter

https://twitter.com/CochraneUK/status/1521478814349631489

 

RCT: Effects of prophylactic oral dextrose gel on neurosensory impairment at 2-year follow-up in late preterm and term infants born at risk of neonatal hypoglycemia.

4 May, 2022 | 10:43h | UTC

Prophylactic Oral Dextrose Gel and Neurosensory Impairment at 2-Year Follow-up of Participants in the hPOD Randomized Trial – JAMA (link to abstract – $ for full-text)

Commentary: New insight into protecting newborns with low blood sugars – University of Auckland

Related:

Cohort Study: No association of neonatal hypoglycemia with academic performance in mid-childhood.

Oral dextrose gel for the treatment of hypoglycemia in newborn infants.

 

Commentary on Twitter

 

Review: Mechanical ventilation in pediatric and neonatal patients.

4 May, 2022 | 10:29h | UTC

Mechanical Ventilation in Pediatric and Neonatal Patients – Frontiers in Physiology

 

AAP Guidance for structuring a pediatric intermediate care unit.

3 May, 2022 | 10:55h | UTC

Guidance for Structuring a Pediatric Intermediate Care Unit – Pediatrics

 

Position Paper: Diagnosis and management of rare cardiomyopathies in adult and pediatric patients.

3 May, 2022 | 10:24h | UTC

Diagnosis and Management of Rare Cardiomyopathies in Adult and Paediatric Patients. A Position Paper of the Italian Society of Cardiology (SIC) and Italian Society of Paediatric Cardiology (SICP) – International Journal of Cardiology

 

AAP Guidance for pediatric end-of-life care.

2 May, 2022 | 00:51h | UTC

Guidance for Pediatric End-of-Life Care – Pediatrics

Related Guidance: End of life care for infants, children and young people with life-limiting conditions: planning and management – National Institute for Health and Care Excellence

 

CDC Report: Acute hepatitis and adenovirus infection among children.

2 May, 2022 | 00:46h | UTC

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

Commentaries:

CDC releases new clinical details in cases of unusual hepatitis in children – CNN

CDC describes 4 tell-tale physical symptoms of the mysterious liver disease that’s spreading among kids in the US and Europe – Insider

CDC report finds no Covid link in children’s hepatitis cases in Alabama – NBC News

Related:

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 

Commentaries on Twitter

 

ECDC publishes Rapid Risk Assessment – Increase in severe acute hepatitis cases of unknown etiology in children.

2 May, 2022 | 00:44h | UTC

ECDC publishes Rapid Risk Assessment – Increase in severe acute hepatitis cases of unknown aetiology in children – European Centre for Disease Prevention and Control

Related:

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 

RCT: Phentermine/Topiramate for the treatment of adolescent obesity.

2 May, 2022 | 00:41h | UTC

Phentermine/Topiramate for the Treatment of Adolescent Obesity – NEJM Evidence

 

Commentary on Twitter

 

M-A: Early neurodevelopment of HIV-exposed uninfected children in the era of antiretroviral therapy.

1 May, 2022 | 23:09h | UTC

Early neurodevelopment of HIV-exposed uninfected children in the era of antiretroviral therapy: a systematic review and meta-analysis – The Lancet Child & Adolescent Health

 

RCT: Extended vs. standard antibiotic course duration in children below 5 years of age hospitalized with community-acquired pneumonia in high-risk settings.

29 Apr, 2022 | 11:16h | UTC

Extended Versus Standard Antibiotic Course Duration in Children <5 Years of Age Hospitalized With Community-acquired Pneumonia in High-risk Settings: Four-week Outcomes of a Multicenter, Double-blind, Parallel, Superiority Randomized Controlled Trial – The Pediatric Infectious Disease Journal

Related:

Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians – Annals of Internal Medicine

Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial – JAMA Pediatrics

Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial – JAMA

Treatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics

Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial – JAMA

Seven versus fourteen Days of Antibiotic Therapy for uncomplicated Gram-negative Bacteremia: a Non-inferiority Randomized Controlled Trial – Clinical Infectious Diseases

Efficacy of short-course antibiotic treatments for community-acquired pneumonia in adults: A systematic review and meta-analysis – Antimicrobial Agents and Chemotherapy

 

Commentary on Twitter

 

WHO reveals shocking extent of exploitative formula milk marketing.

29 Apr, 2022 | 10:58h | UTC

News Release: WHO reveals shocking extent of exploitative formula milk marketing – World Health Organization

Report: Scope and impact of digital marketing strategies for promoting breastmilk substitutes – World Health Organization

Related: More than half of parents and pregnant women exposed to aggressive formula milk marketing – WHO, UNICEF – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

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