Pain Medicine
M-A: Comparison of Amitriptyline with other FDA–approved treatments for fibromyalgia.
20 May, 2022 | 10:49h | UTC
Discovery reveals blocking inflammation may lead to chronic pain.
19 May, 2022 | 11:06h | UTCNews Release: Discovery reveals blocking inflammation may lead to chronic pain – McGill University
Original Study: Acute inflammatory response via neutrophil activation protects against the development of chronic pain – Science Translational Medicine
Commentary on Twitter
Challenging medical dogma:
A very important new report suggests that non-steroidal inflammatory medications for acute pain can lead to chronic painhttps://t.co/Z8yjFFBCkK @ScienceTM https://t.co/YGjkXbvNTa pic.twitter.com/f4xVezAhau— Eric Topol (@EricTopol) May 18, 2022
AUA Guideline: Diagnosis and treatment interstitial cystitis/bladder pain syndrome.
13 May, 2022 | 11:07h | UTC
M-A: Comparative impact of pharmacological therapies on cluster headache management.
12 May, 2022 | 08:01h | UTC
M-A: Effect of intravenous dexamethasone on postoperative pain in patients undergoing total knee arthroplasty.
11 May, 2022 | 10:52h | UTC
Systematic Review: Prevalence of opioid use disorder among patients with cancer-related pain.
11 May, 2022 | 10:46h | UTC
Review: Pharmacologic management of persistent pain in cancer survivors.
6 May, 2022 | 10:34h | UTCPharmacologic Management of Persistent Pain in Cancer Survivors – Drugs
Review: Diagnosis and management of lumbar spinal stenosis.
4 May, 2022 | 10:45h | UTCDiagnosis and Management of Lumbar Spinal Stenosis: A Review – JAMA (free for a limited period)
Audio Clinical Review: Lumbar Spinal Stenosis: A Review – JAMA
Review: Opioids and falls risk in older adults.
4 May, 2022 | 10:27h | UTCOpioids and Falls Risk in Older Adults: A Narrative Review – Drugs & Aging
Review: Equianalgesia, opioid switch and opioid association in different clinical settings.
3 May, 2022 | 10:42h | UTC
NICE chronic primary pain guidelines: what the busy GP needs to know.
2 May, 2022 | 00:25h | UTCOriginal Guideline: Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain – National Institute for Health and Care Excellence
Consensus practice guidelines on interventions for cervical spine (facet) joint pain from a multispecialty international working group.
26 Apr, 2022 | 07:28h | UTC
UK drug regulator advises patients and doctors against the use of Pregabalin during pregnancy due to a possible increased risk of congenital malformations.
22 Apr, 2022 | 09:31h | UTCSee also: Pregabalin and risks in pregnancy – Medicines and Healthcare products Regulatory Agency
Source: Avoid prescribing pregabalin during pregnancy if possible, says UK drug regulator – The BMJ ($)
Commentary on Twitter
The Medicines and Healthcare Products Regulatory Agency (@MHRAgovuk) has strengthened its warning about avoiding pregabalin during pregnancy after new data showed an increased risk of major congenital malformations associated with the drug https://t.co/ghGvqCqA0C
— The BMJ (@bmj_latest) April 22, 2022
The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates.
18 Apr, 2022 | 10:03h | UTCNews Release: Global estimates of headaches suggest disorder impacts over 50 percent of the population – BMC
RCT: A home-based, walking exercise behavior change intervention increased walking distance in adults with peripheral artery disease.
13 Apr, 2022 | 11:02h | UTCEffect of a Home-Based, Walking Exercise Behavior Change Intervention vs Usual Care on Walking in Adults With Peripheral Artery Disease: The MOSAIC Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
In this study, among adults with peripheral artery disease, a home-based, #walking #exercise behavior change intervention, compared with usual care, increased 6-minute walking distance at 3 months. https://t.co/5ea3YOWlN0 @LindsayBearne pic.twitter.com/s06ONnki9y
— JAMA (@JAMA_current) April 12, 2022
Review: Perioperative opioids, the opioid crisis, and the anesthesiologist.
12 Apr, 2022 | 08:17h | UTCPerioperative Opioids, the Opioid Crisis, and the Anesthesiologist – Anesthesiology
M-A: Interventions to reduce opioid prescriptions following urological surgery.
11 Apr, 2022 | 00:42h | UTC
Review | Chronic pain and infection: mechanisms, causes, conditions, treatments, and controversies.
8 Apr, 2022 | 10:27h | UTC
RCT: Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anesthetic injection for hip osteoarthritis.
7 Apr, 2022 | 08:37h | UTCNews Release: Steroid injections may provide longer lasting benefits for hip pain than current best care – BMJ
Commentary on Twitter
Adding an ultrasound guided corticosteroid and local anaesthetic injection to advice and education offers rapid and sustained improvements in pain and function, finds new research https://t.co/fQHzvKv2wL
— The BMJ (@bmj_latest) April 7, 2022
RCT: Effect of intramuscular vs. intra-articular glucocorticoid injection on pain among adults with knee osteoarthritis.
7 Apr, 2022 | 08:35h | UTC
Commentary on Twitter
This RCT found IM steroid injections were inferior to intrarticular injections for reducing pain in patients with knee osteoarthritis at 4 weeks but were noninferior at 8 and 24 weeks after injection. https://t.co/opq1C2BP8c pic.twitter.com/ucx4lvRDJQ
— JAMA Network Open (@JAMANetworkOpen) April 5, 2022
Systematic Review: Algorithm‐based pain management for people with dementia in nursing homes.
7 Apr, 2022 | 07:52h | UTCAlgorithm‐based pain management for people with dementia in nursing homes – Cochrane Library
Major burns: part 2. Anesthesia, intensive care and pain management.
7 Apr, 2022 | 07:59h | UTCMajor burns: part 2. Anaesthesia, intensive care and pain management – BJA Education
See also: Major burns: Part 1. Epidemiology, pathophysiology and initial management.
Global, regional, and national trends in opioid analgesic consumption from 2015 to 2019.
6 Apr, 2022 | 10:49h | UTCNews Release: Global disparities persist in opioid painkiller access – University College London
Invited Commentary: Closing the global pain divide: balancing access and excess – The Lancet Public Health
Commentary on Twitter (article and images under a Creative Commons Attribution (CC BY 4.0 license)
Just Out @TheLancetPH 🚨
Global #opioids consumption increased from 2015 to 2019‼️#Disparities in opioid💊consumption remained, indicating potential inadequate access to essential pain relief in countries with low consumption🌐https://t.co/bkcdgLy3ZP pic.twitter.com/RUGl1gbiTw— Gil Morgan, MD (@weoncologists) April 1, 2022
Guideline: Revision of pharmacological treatment recommendations for cancer pain.
6 Apr, 2022 | 09:49h | UTC
Opinion | Medicinal cannabis for chronic pain: the Bermuda triangle of low-quality studies, countless meta-analyses and conflicting recommendations.
5 Apr, 2022 | 08:52h | UTCRelated:
M-A: Birth outcomes of neonates exposed to marijuana in utero.
Cannabis-related allergies: an international overview and consensus recommendations.
Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.
Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain.
Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.
Guideline: Medical cannabis or cannabinoids for chronic pain.
NICE Guideline: Cannabis-Based Medicinal Products
Short Review: Drug Interactions with Cannabinoids
Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain
Review: Considerations for cannabinoids in perioperative care by anesthesiologists.
Review: Cannabis-based Medicines and the Perioperative Physician
Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know