Pain Medicine
M-A | Scalp block for postoperative pain after craniotomy.
21 Oct, 2022 | 12:51h | UTC
Crossover RCT | Spinal cord burst stimulation does not improve disability in chronic radicular pain after lumbar spine surgery.
19 Oct, 2022 | 14:29h | UTCEffect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
Among patients with chronic radicular pain after lumbar spine surgery, spinal cord burst stimulation, compared with placebo stimulation, resulted in no significant difference in back pain–related disability. https://t.co/XGiRRB4Njm #Research
— JAMA (@JAMA_current) October 18, 2022
RCT | In abortion surgery, Esketamine plus Propofol can reduce hypotension compared to Fentanyl plus Propofol.
14 Oct, 2022 | 13:58h | UTCCommentary: Esketamine as an adjunct with propofol and fentanyl to avoid perioperative hypotension – Physician’s Weekly
RCT | A postoperative multimodal opioid-sparing protocol can reduce opioid consumption after knee or shoulder arthroscopy.
5 Oct, 2022 | 13:57h | UTCEffect of a Postoperative Multimodal Opioid-Sparing Protocol vs Standard Opioid Prescribing on Postoperative Opioid Consumption After Knee or Shoulder Arthroscopy: A Randomized Clinical Trial – JAMA (free for a limited period)
News Release: Orthopedic surgery patients do fine without opioid painkillers – McMaster University
See also: Visual Abstract
Video Editor’s Note: Effect of an Opioid-Sparing Protocol vs Standard Prescribing on Opioid Consumption After Knee or Shoulder Arthroscopy
Review | Regional anesthesia and acute perioperative pain management in thoracic surgery.
30 Sep, 2022 | 12:32h | UTC
ASCO Guideline | Integrative medicine for pain management in oncology.
21 Sep, 2022 | 13:22h | UTC
Observational study suggests an increased risk of adverse events with the use of perioperative Gabapentin for pain management.
21 Sep, 2022 | 13:20h | UTCPerioperative Gabapentin Use and In-Hospital Adverse Clinical Events Among Older Adults After Major Surgery – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Perioperative Gabapentin Use in Older Adults: Revisiting Multimodal Pain Management – JAMA Internal Medicine (free for a limited period)
Commentary on Twitter
Study suggests that careful risk-benefit assessment is needed before prescribing #gabapentin for perioperative #PainManagement to older patients. https://t.co/GDxupdEjeT #Research
— JAMA Internal Medicine (@JAMAInternalMed) September 19, 2022
Guideline | Perioperative care of patients undergoing major complex spinal instrumentation surgery.
11 Sep, 2022 | 22:49h | UTC
Systematic Review | Opioid agonist treatment for people who are dependent on pharmaceutical opioids.
6 Sep, 2022 | 14:31h | UTCOpioid agonist treatment for people who are dependent on pharmaceutical opioids – Cochrane Library
Cluster RCT | Effect of different interventions to help primary care clinicians avoid unsafe opioid prescribing in opioid-naive patients with acute noncancer pain.
31 Aug, 2022 | 11:33h | UTC
Commentary on Twitter
This cluster randomized clinical trial found that clinician comparison email feedback had the potential to decrease harm from opioid prescriptions for acute noncancer pain. @RxEricWright @walidgellad #VisualAbstract https://t.co/BizLH13lau pic.twitter.com/EEbdqWRqig
— JAMA Health Forum (@JAMAHealthForum) July 29, 2022
Guideline | Management of medication overuse and medication overuse headache.
30 Aug, 2022 | 12:08h | UTC
Randomized Crossover Trial | In patients with diabetic neuropathic pain, amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin were similarly effective.
25 Aug, 2022 | 12:14h | UTC
Cohort Study | Characteristics of prescription opioid analgesics in pregnancy and risk of neonatal opioid withdrawal syndrome in newborns.
25 Aug, 2022 | 12:02h | UTC
Study Commentary | Is the evidence strong for spinal cord stimulation for diabetic neuropathy? Not all experts agree.
25 Aug, 2022 | 11:52h | UTCOriginal Study: RCT: Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy
Review | Long COVID headache.
15 Aug, 2022 | 12:25h | UTCLong COVID headache – The Journal of Headache and Pain
Commentary on Twitter
#Headache is among the most frequent symptoms persisting or newly developing after #coronavirus disease 2019 (COVID-19) as part of the so-called long #COVID syndrome. Learn more: https://t.co/v1V2jZBluq pic.twitter.com/X6eAgaOaBF
— European Headache Federation (@EHF_Official) August 4, 2022
Under a http://creativecommons.org/licenses/by/4.0/ license
RCT | Small trial suggests intraosseous morphine may decrease postoperative pain and pain medication use after total knee arthroplasty.
15 Aug, 2022 | 12:03h | UTCNews Release: A new way to control pain after knee replacement surgery – Houston Methodist
Review | The COVID-19 pandemic and its consequences for chronic pain.
12 Aug, 2022 | 15:02h | UTCThe COVID-19 pandemic and its consequences for chronic pain: a narrative review – Anaesthesia
Commentary on Twitter
🔐Time to pay attention to the consequences of persistent pain in patients after any severity of COVID-19, with increased risk of post-intensive care syndrome in patients requiring ICU care?@harshamd5 @ANels_MD @NarouzeMD #FreeForAWeek
🔗https://t.co/NaafjxCbXz pic.twitter.com/Zj2OGIPniP
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) August 1, 2022
RCT | Effect of adjunctive acupuncture on pain relief among emergency department patients with acute renal colic due to urolithiasis.
11 Aug, 2022 | 12:06h | UTCCommentary: Adjunctive Acupuncture May Speed Relief From Pain of Renal Colic – HealthDay
Commentary on Twitter
In this #RCT of emergency department patients with renal colic who received IM NSAIDs, acupuncture provided additional fast short-term pain relief for compared with sham acupuncture. #OrigInvestigation https://t.co/7i2wk86hif pic.twitter.com/VHNDFqOcOx
— JAMA Network Open (@JAMANetworkOpen) August 9, 2022
Review | Chronic post-surgical pain – update on incidence, risk factors and preventive treatment options.
10 Aug, 2022 | 12:12h | UTC
RCT | Efficacy and safety of intravenous acetaminophen (2 g/day) for reducing opioid consumption in Chinese adults after elective orthopedic surgery.
9 Aug, 2022 | 12:39h | UTC
Cohort Study | The risk of opioid overdose is increased with concomitant use of oxycodone and selective serotonin reuptake inhibitors that are inhibitors of oxycodone metabolism.
4 Aug, 2022 | 14:27h | UTCCommentary from the author: Taking certain opioids while on commonly prescribed antidepressants may increase the risk of overdose – The Conversation
Commentary on Twitter
This cohort study found that concomitant use of oxycodone with potent CYP2D6-inhibiting serotonin reuptake inhibitors (SSRIs, eg. fluoxetine or paroxetine) is associated with an increased risk of overdose. https://t.co/Eol89RHWAu
— JAMA Network Open (@JAMANetworkOpen) February 24, 2022
RCT | Effect of graded sensorimotor retraining on pain intensity in patients with chronic low back pain.
3 Aug, 2022 | 14:08h | UTCEffect of Graded Sensorimotor Retraining on Pain Intensity in Patients With Chronic Low Back Pain: A Randomized Clinical Trial – JAMA (free for a limited period)
News release: An effective new treatment for chronic back pain targets the nervous system – University of New South Wales
Commentary on Twitter
A graded sensorimotor retraining intervention, compared with a sham procedure and attention control, resulted in a statistically significant improvement in pain intensity at 18 weeks. https://t.co/MXO89JeOSe pic.twitter.com/0A865RWW85
— JAMA (@JAMA_current) August 2, 2022
Brief Review | Monitoring pain in the intensive care unit.
1 Aug, 2022 | 12:30h | UTCMonitoring pain in the intensive care unit (ICU) – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Monitoring pain in #ICU
➡️ self‐assessment tools in pts able to self‐report
➡️ observational behavioural scales in pts unable to self‐report
➡️ physiologic parameters in pts unable to self‐report nor express behaviours (deep sedaution, NMBAs)#FOAMcc
🖇 https://t.co/SaD1BBxSNw pic.twitter.com/81tNNvnTDe— Intensive Care Medicine (@yourICM) July 30, 2022
RCT | Effects of walking exercise at a pace with vs. without ischemic leg symptoms on functional performance measures in people with lower extremity peripheral artery disease.
28 Jul, 2022 | 13:27h | UTCNews Release: ‘No pain, no gain’ approach improves walking ability with peripheral artery disease – American Heart Association
RCT | Intra-articular botulinum toxin A injection for painful base-of-thumb osteoarthritis.
27 Jul, 2022 | 11:56h | UTCIntra-articular botulinum toxin A injection for painful base-of-thumb osteoarthritis: a double-blind, randomised, controlled, phase 3 trial (RHIBOT) – The Lancet Rheumatology (link to abstract – $ for full-text)
Commentaries:
Botulinum toxin A injection may ease base-of-thumb osteoarthritis pain – medwire News
Commentary on Twitter
NEW RESEARCH—Intra-articular botulinum toxin A injection for painful base-of-thumb #osteoarthritis: a double-blind, randomised, controlled, phase 3 trial (RHIBOT) https://t.co/pY4ZQdW6p9 @cchnguyen pic.twitter.com/KT4XLzhIlb
— The Lancet Rheumatology (@TheLancetRheum) June 24, 2022