Pain Medicine
Meta-Analysis: Comparative Efficacy of Therapeutics for Chronic Cancer Pain
4 Apr, 2019 | 22:50h | UTCComparative Efficacy of Therapeutics for Chronic Cancer Pain: A Bayesian Network Meta-Analysis – Journal of Clinical Oncology (free for a limited period)
Meta-Analysis: Beta-blockers for the Prevention of Headache in Adults
4 Apr, 2019 | 22:49h | UTC
Consensus Statement: Perioperative Management of Patients on Preoperative Opioid Therapy
4 Apr, 2019 | 12:52h | UTC
Women with Newly Discovered Gene Mutation Feels Almost no Pain
1 Apr, 2019 | 12:00h | UTCCommentaries: Woman with novel gene mutation lives almost pain-free – University College London (free) AND The case of a woman who feels almost no pain leads scientists to a new gene mutation – STAT (free) AND At 71, She’s Never Felt Pain or Anxiety. Now Scientists Know Why. – The New York Times (10 articles per month are free) AND The woman who doesn’t feel pain – BBC (free)
Randomized Trial: Prehospital Analgesia With Intranasal Ketamine
1 Apr, 2019 | 11:57h | UTC
Position Paper: Diagnosis and Management of Complex Regional Pain Syndrome
29 Mar, 2019 | 07:36h | UTCRelated: Complex regional pain syndrome in adults (2nd edition) – UK guidelines for diagnosis, referral and management in primary and secondary care 2018 – Royal College of Physicians (free PDF)
Less is More: A Clinical Overview of Off-label Use of Gabapentinoid Drugs
26 Mar, 2019 | 01:42h | UTCA Clinical Overview of Off-label Use of Gabapentinoid Drugs – JAMA Internal Medicine (free for a limited period)
Related Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain (free study and commentaries)
“Clinicians who prescribe gabapentinoids off-label for pain should be aware of the limited evidence and should acknowledge to patients that potential benefits are uncertain for most off-label uses.”
EAN Guideline on Trigeminal Neuralgia
14 Mar, 2019 | 00:50h | UTCEAN guideline on trigeminal neuralgia – European Journal of Neurology (free PDF)
Low Back Pain, a Comprehensive Review: Pathophysiology, Diagnosis, and Treatment
13 Mar, 2019 | 05:52h | UTC
Consensus on Noninvasive CNS Neuromodulation for Chronic Pain Management
12 Mar, 2019 | 13:06h | UTC
Cochrane Review: Paracetamol Not Much Better Than Placebo for Knee and Hip Osteoarthritis
28 Feb, 2019 | 06:02h | UTCParacetamol versus placebo for knee and hip osteoarthritis – Cochrane Library (free)
Summary: Paracetamol for treating people with hip or knee osteoarthritis – Cochrane Library (free)
Related: Paracetamol: widely used and largely ineffective (free)
Related Commentary on Twitter
New Cochrane Review – 'Paracetamol (acetaminophen) versus placebo for knee and hip osteoarthritis' https://t.co/gGQs23456x @CochraneMSK High‐quality evidence indicated that paracetamol provided only minimal improvements in pain and function for people with hip/knee osteoarthritis
— The Cochrane Library (@CochraneLibrary) February 25, 2019
Meta‐analysis on Non‐opioid Analgesics in Palliative Medicine
18 Feb, 2019 | 17:02h | UTC
Meta-Analysis: Benefits and Harms of Pregabalin in the Management of Neuropathic Pain
15 Feb, 2019 | 00:51h | UTCRelated Cochrane Review (just published): Pregabalin for neuropathic pain in adults – Cochrane Library (free) and Commentary: Pregabalin for neuropathic pain: balancing benefits and harms – Evidently Cochrane (free)
Randomized Trial: Effects of Paracetamol + Ibuprofen vs Either Alone on Morphine Consumption After Total Hip Arthroplasty
14 Feb, 2019 | 01:50h | UTCEffect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Ibuprofen may be a ‘reasonable option’ for analgesia after hip replacement – medwire News (free) AND Acetaminophen Plus Ibuprofen Linked to Less Morphine Use After Hip Arthroplasty – NEJM Journal Watch (free) AND Paracetamol plus ibuprofen significantly reduces post-operative morphine use in total hip arthroplasty patients – 2 Minute Medicine (free)
Randomized Trial: Compounded Topical Pain Creams No Better Than Placebo to Treat Localized Chronic Pain
11 Feb, 2019 | 21:32h | UTCCompounded Topical Pain Creams to Treat Localized Chronic Pain: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Topical creams likely ineffective in treating localized chronic pain – 2 Minute Medicine (free) AND Research pushes back on benefits of compounded topical pain creams – Johns Hopkins Medicine (free) AND Compounded Pain Creams – Expensive Placebos? – RheumNow (free)
BMJ Guideline: Subacromial Decompression Surgery For Adults With Shoulder Pain Does Not Improve Outcomes
7 Feb, 2019 | 02:03h | UTCCommentaries: Expert panel strongly recommends against surgery for the most common shoulder pain – MedicalXpress (free) AND Guidelines Recommend Against Surgery for Subacromial Pain Syndrome – NEJM Journal Watch (free)
Related Systematic Reviews: Subacromial decompression surgery for adults with shoulder pain: a systematic review with meta-analysis – British Journal of Sports Medicine (free) AND Subacromial Decompression Surgery for Rotator Cuff Disease – Cochrane Library (link to study and randomized trials on the subject)
Abdominal Wall Pain: A Common Clinical Problem
7 Feb, 2019 | 01:01h | UTCAbdominal Wall Pain: A Common Clinical Problem – Mayo Clinic Proceedings (free for a limited period)
WHO Guidelines for the Management of Cancer Pain
5 Feb, 2019 | 00:35h | UTC
Report: The Efficacy and Safety of Vertebral Augmentation
27 Jan, 2019 | 20:19h | UTCCommentaries: Spinal Fractures Can Be Terribly Painful. A Common Treatment Isn’t Helping – The New York Times (10 articles per month are free) AND Spinal Fusions Ineffective for Fracture Pain, Says ASBMR – Medscape (free registration required)
Related: Randomized Trial: Vertebroplasty vs. Sham Procedure for Acute Osteoporotic Vertebral Compression Fractures – The BMJ (free study and commentary) AND Cochrane Review: percutaneous vertebroplasty for osteoporotic vertebral compression fracture (free article and summary)
Management of Complex Regional Pain Syndrome of the Hand
27 Jan, 2019 | 18:37h | UTCManagement of complex regional pain syndrome of the hand – Orthopaedics and Trauma (free)
Randomized Trial: Comparative Effectiveness of Nonsurgical Treatment Methods in Lumbar Spinal Stenosis
24 Jan, 2019 | 16:12h | UTCCommentary: Lumbar Spinal Stenosis: Non-Surgical Options Compared – MedicalResearch.com (free)
New IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11)
22 Jan, 2019 | 00:29h | UTCCommentary: IASP Updates Classification of Chronic Pain – Clinical Advisor (free)
Related Commentary on Twitter
Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11) #PainJournal https://t.co/Riegvjag5N pic.twitter.com/9hquW4dDa1
— PAIN Journal (@PAINthejournal) January 16, 2019
“Opioids Don’t Work for Most People with Chronic Pain. So Why do We Still Prescribe Them?”
22 Jan, 2019 | 00:26h | UTCRelated study: Meta-Analysis: Opioids for Chronic Noncancer Pain (link to abstract and commentaries)
See also: Opioid Wisely – Choosing Wisely Canada (free) AND Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)
Exercise-induced Hypoalgesia: A Meta-analysis of Exercise Dosing for the Treatment of Chronic Pain
21 Jan, 2019 | 12:37h | UTC
Systematic Review: Subacromial Decompression Surgery for Rotator Cuff Disease
20 Jan, 2019 | 17:14h | UTCSubacromial decompression surgery for rotator cuff disease – Cochrane Library (free)
Summary: Surgery for rotator cuff disease (free)
Related Studies: Subacromial Decompression vs Diagnostic Arthroscopy for Shoulder Impingement (free study and commentaries) AND Arthroscopic subacromial decompression for subacromial shoulder pain (free study and commentaries)
“The data in this review do not support the use of subacromial decompression in the treatment of rotator cuff disease manifest as painful shoulder impingement.”