Pain Medicine
Meta-Analysis: Acupuncture may Reduce Pain Intensity in Patients with Cancer
5 Jan, 2020 | 13:19h | UTCCommentaries: Acupunture may help reduce cancer pain, analysis finds – UPI (free) AND Acupuncture, acupressure may help cancer patients control pain – MedicalXpress (free)
Meta-analysis: Pain in Chronic Inflammatory Demyelinating Polyradiculoneuropathy
3 Dec, 2019 | 00:55h | UTCRelated: Chronic Inflammatory Demyelinating Polyneuropathy: Update on Diagnosis, Immunopathogenesis and Treatment (free reviews)
FDA Issues Safety Warning on Cannabidiol Products
28 Nov, 2019 | 10:29h | UTCCommentaries: FDA’s Warning On CBD: Cannabis Stocks Drop, Companies Object – Forbes (free) AND ‘CBD has the potential to harm you,’ FDA warns consumers – MarketWatch (free)
Related: Cannabidiol Products Are Everywhere, but Should People Be Using Them? – JAMA (free for a limited period) AND NICE Guideline: Cannabis-Based Medicinal Products (free Guideline and other resources)
Systematic Review: Pharmacological Interventions for the Prevention of Acute Postoperative Pain in Adults Following Brain Surgery
22 Nov, 2019 | 08:24h | UTCPharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery – Cochrane Library (free)
Summary: Preventing pain after brain surgery – Cochrane Library (free)
Related Commentary on Twitter
🆕@Cochrane_ACE REVIEW: 'Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery' https://t.co/0jvQhntvfy High-quality evidence supports ⬇️ postoperative pain with NSAIDs, evidence is less certain for other interventions
— Cochrane Anaesthesia & Emergency and Critical Care (@Cochrane_ACE) November 21, 2019
Perspective: Cannabidiol Products Are Everywhere, but Should People Be Using Them?
21 Nov, 2019 | 08:16h | UTCCannabidiol Products Are Everywhere, but Should People Be Using Them? – JAMA (free for a limited period)
Related: NICE Guideline: Cannabis-Based Medicinal Products (free Guideline and other resources)
NICE Guideline: Cannabis-Based Medicinal Products
12 Nov, 2019 | 11:27h | UTCCannabis-based medicinal products – National Institute for Health and Care Excellence (free)
Commentaries: Drug experts on the new guidance for medicinal cannabis – The Conversation (free) AND Ian Hamilton: New guidelines for prescribing medicinal cannabis—another dashed hope for patients – The BMJ Opinion (free)
Related: Guideline for Prescribing Medical Cannabinoids in Primary Care – Canadian Family Physician (free) AND Cannabinoids for Chronic Pain – Therapeutics Initiative AND (free) Meta-Analysis: Insufficient Evidence for The Use of Cannabinoids for Treating Mental Disorders – The Lancet Psychiatry (link to abstract and commentaries) AND The Effects of Cannabis Among Adults With Chronic Pain – Annals of Internal Medicine (link to abstract and commentaries)
“In short, NICE has concluded that more research is needed before it can recommend the use of cannabis-based products for medicinal use.” (from The Conversation)
#ACR19 – Randomized Trial: Low-Dose Corticosteroids for Short Periods Effective and Safe for Hand Osteoarthritis
12 Nov, 2019 | 11:23h | UTCResults of a 6-week treatment with 10 mg prednisolone in patients with hand osteoarthritis (HOPE): a double-blind, randomised, placebo-controlled trial – The Lancet (free registration required)
Commentaries: Low-Dose Oral Prednisolone Substantially Improves Pain and Function in Hand Osteoarthritis – American College of Rheumatology (free) AND Short-term prednisolone offers HOPE for painful hand osteoarthritis – Medicine Matters (free) AND Short Course of Low-Dose Prednisolone for Painful Hand Osteoarthritis – MedicalResearch.com (free)
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting
#ACR19 – [Not Published Yet] Meta-Analysis: For People with Osteoarthritis, Opioids Offer Minor Pain Relief and Function Benefits, but No Quality of Life Benefit
12 Nov, 2019 | 10:48h | UTCAbstract: Is There Any Role for Opioids in the Management of OA? (free)
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting
Meta-Analysis: Mind-Body Therapies for Opioid-Treated Pain
6 Nov, 2019 | 08:10h | UTCMind-Body Therapies for Opioid-Treated Pain: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Commentaries: Study highlights role of mind-body therapies in addressing opioid-treated pain – News Medical (free) AND Meditation, Mindfulness Hold Promise for Pain Treatment, Curbing Opioid Use – U.S. News (free)
Meta-Analysis: Which Modes of Exercise are Most Effective for Treating Low Back Pain?
4 Nov, 2019 | 01:19h | UTC
Related Commentary on Twitter
Hot off the press 🔥🔓🔥
Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis
👀👀👇👇https://t.co/MTLlPbew6Z pic.twitter.com/wiOK4ukyig
— Physio Meets Science (@PhysioMeScience) October 30, 2019
Podcast: Emerging Applications for Ketamine
4 Nov, 2019 | 00:50h | UTCEmerging Applications for Ketamine – JAMA (free audio)
Related Resources:
Ketamine for Depression: Ketamine and depression: a narrative review – Drug Design, Development and Therapy (free)
Study: In Utero Acetaminophen Exposure Linked to Increased Risk of ADHD and Autism Spectrum Disorder in Childhood
31 Oct, 2019 | 08:12h | UTCAssociation of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood – JAMA Psychiatry (free for a limited period)
Commentaries: NIH-funded study suggests acetaminophen exposure in pregnancy linked to higher risk of ADHD, autism – NIH News Releases (free) AND Babies at higher risk for ADHD, autism if pregnant moms took acetaminophen – Reuters (free) AND Expert reaction to study looking at paracetamol in pregnancy and autism, ADHD and other developmental disabilities in children – Science Media Centre (free)
Related Studies: Cohort Study: Associations Between Paracetamol Intake Between 18 and 32 Weeks Gestation and Neurocognitive Outcomes in the Child (free) AND Meta-Analysis: Prenatal Exposure to Acetaminophen and Risk for ADHD and Autistic Spectrum Disorder (free) AND Prenatal Exposure to Acetaminophen and Risk of ADHD (free)
Treatment for Acute Pain: An Evidence Map
30 Oct, 2019 | 07:50h | UTCTreatment for Acute Pain: An Evidence Map – Agency for Healthcare Research and Quality (free PDF)
See also: Summary (free)
Chronic Inflammatory Demyelinating Polyneuropathy: Update on Diagnosis, Immunopathogenesis and Treatment
29 Oct, 2019 | 08:44h | UTCPodcast: CIDP and Update – Journal of Neurology, Neurosurgery & Psychiatry (free)
Related Reviews: Treatments for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): an overview of systematic reviews – Cochrane Library (free) AND History, Diagnosis, and Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy – Mayo Clinic Proceedings (free)
Interest in Cannabidiol Products Keeps Soaring Despite Limited Evidence in Humans
27 Oct, 2019 | 19:29h | UTCTrends in Internet Searches for Cannabidiol (CBD) in the United States – JAMA Network Open (free)
Commentaries: Interest in CBD products keeps soaring, but health experts wary – HealthDay (free) AND Online Searches For CBD Skyrocket – MedicalResearch.com (free)
Related Commentary on Twitter
"Interest in CBD products keeps soaring, but health experts wary" https://t.co/TP50a31bbP via @medical_xpress
"At this time there are no known benefits for taking CBD over-the-counter. #CBD is this generation's snake oil…"
Studies "in humans are still limited…"#CBDHype.
— Timothy Caulfield (@CaulfieldTim) October 25, 2019
Preventing Opioid Prescription After Major Surgery: A Scoping Review of Opioid-free Analgesia
25 Oct, 2019 | 08:44h | UTCRelated Review: The rising tide of opioid use and abuse: the role of the anesthesiologist – Perioperative Medicine (free)
Systematic Review: Pharmacological Interventions for Treating Chronic Prostatitis/Chronic Pelvic Pain Syndrome
25 Oct, 2019 | 08:15h | UTCPharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome – Cochrane Library (free)
Summary: Intervention for treating chronic prostatitis and chronic pelvic pain in men – Cochrane Library (free)
Chronified Pain Following Operative Procedures: The Place of Locoregional and Systemic Local Anesthetics
22 Oct, 2019 | 07:26h | UTC
Systematic Review: Continuous Local Anesthetic Wound Infusion for Postoperative Pain After Midline Laparotomy for Colorectal Resection in Adults
20 Oct, 2019 | 22:31h | UTCContinuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection in adults – Cochrane Library (free)
Updated NICE Guideline: Diabetic Foot Problems
15 Oct, 2019 | 10:47h | UTCRelated: The management of diabetic foot: A clinical practice guideline by the Society for Vascular Surgery in collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine (free) AND Diabetic foot – The BMJ (free) AND Diagnosis and Management of Diabetic Foot Complications – American Diabetes Association (free) AND Prevention, assessment, diagnosis and management of diabetic foot based on clinical practice guidelines: A systematic review – Medicine (free)
Podcast: Osteoarthritis Master Class
15 Oct, 2019 | 10:22h | UTCSee also: Episodes List
[Abstract Only] Randomized Trial: Oral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries
15 Oct, 2019 | 10:14h | UTCOral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary: RCT – APAP Only vs APAP-Ibuprofen-Codeine Combo – Journal Feed (free)
Meta-Analysis: Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management
14 Oct, 2019 | 08:30h | UTCSource: EvidenceAlerts
HHS Guide for Clinicians on the Appropriate Dosage Reduction or Discontinuation of Long-Term Opioid Analgesics
11 Oct, 2019 | 09:44h | UTCNews Release: HHS Announces Guide for Appropriate Tapering or Discontinuation of Long-Term Opioid Use – U.S. Department of Health and Human Services (free) AND
Commentaries: Patient-Centered Reduction or Discontinuation of Long-term Opioid Analgesics: The HHS Guide for Clinicians – JAMA (free for a limited period) AND With a new guide to tapering opioids, federal health officials seek a balanced approach to prescribing – STAT (free) AND Don’t Force Patients Off Opioids Abruptly, New Guidelines Say, Warning Of Severe Risks – NPR (free)
Author Interview: The HHS Guide to Patient-Centered Dose Reduction or Discontinuation of Long-term Opioids – JAMA (free)
Related: Pain Management With Opioids in 2019-2020 – JAMA (free registration required)
A Comprehensive Algorithm for Management of Neuropathic Pain
4 Oct, 2019 | 08:06h | UTCA Comprehensive Algorithm for Management of Neuropathic Pain – Pain Medicine (free)
Related Guidelines: Neuropathic pain in adults: pharmacological management in non-specialist settings – National Institute for Health and Care Excellence (free) AND Pharmacologic management of chronic neuropathic pain: Review of the Canadian Pain Society consensus statement – Canadian Family Physician (free) AND Executive summary of the Clinical Guidelines of Pharmacotherapy for Neuropathic Pain: second edition by the Japanese Society of Pain Clinicians – Journal of Anesthesia (free)