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Orthopedics (all articles)

Study: Targeted Neurotechnology Restores Walking in Humans with Spinal Cord Injury

2 Nov, 2018 | 03:35h | UTC

Targeted neurotechnology restores walking in humans with spinal cord injury – Nature (free)

Editorial: Paralysed people walk again after spinal-cord stimulation (free)

Commentaries: Spinal implant helps three paralysed men walk again – BBC (free) AND Once Paralyzed, Three Men Take Steps Again With Spinal Implant – The New York Times (10 articles per month are free)

 


Study: Deep Neural Network Improves Fracture Detection by Clinicians

26 Oct, 2018 | 02:05h | UTC

Deep neural network improves fracture detection by clinicians – Proceedings of the National Academy of Sciences (free)

“How to reduce emergency doctor misinterpretation of wrist X-rays for fracture by nearly 50%? Deep learning AI, of course” (via @EricTopol see Tweet)

 


Randomized Trial: Corticosteroid Injection vs. Night Splints for Carpal Tunnel Syndrome

26 Oct, 2018 | 01:40h | UTC

The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial – The Lancet (free)

Invited Commentary: Steroid injection or wrist splint for first-time carpal tunnel syndrome? (free)

“A single corticosteroid injection shows superior clinical effectiveness at 6 weeks compared with night-resting splints, making it the treatment of choice for rapid symptom response in mild or moderate carpal tunnel syndrome presenting in primary care.”

 


Cohort Study: Aspirin vs. Other Anticoagulants for Prevention of VTE After Total Knee Arthroplasty

19 Oct, 2018 | 00:06h | UTC

Association of Aspirin With Prevention of Venous Thromboembolism in Patients After Total Knee Arthroplasty Compared With Other Anticoagulants: A Noninferiority Analysis – JAMA Surgery (link to abstract – $ for full-text)

Commentaries: More Research Supports Use of Aspirin Alone to Prevent VTE After Knee Replacement Surgery – TCTMD (free) AND Aspirin Noninferior to Other Anticoagulants in Knee Arthroplasty – Journal Watch (free)

Related Randomized Trial: Aspirin Starting Five Days After Hip or Knee Arthroplasty for VTE Prophylaxis (link to abstract, video summary and commentary)

 


Perspective: Should You Have Knee Replacement Surgery?

16 Oct, 2018 | 21:28h | UTC

Should You Have Knee Replacement Surgery? – The New York Times (10 articles per month are free)

“Some experts question whether the surgery is being done too often or too soon on patients who have not adequately explored less invasive approaches.”

 


Randomized Trial: Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal Tears

5 Oct, 2018 | 02:21h | UTC

Effect of Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal Tears: The ESCAPE Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: PT an Alternative to Surgery for Some Meniscal Tears – Physician’s First Watch (free)

Related: Adverse Outcomes After Arthroscopic Partial Meniscectomy (free study, commentary and guideline on the subject)

“Our Dutch multi center RCT demonstrates noninferiority of physical therapy compared with early surgery with arthroscopic partial meniscectomy for improving self-reported knee function in patients with nonobstructive meniscal tears.” (via @RudolfPoolman see Tweet)

 


Randomized Trial: Low-Dose Amitriptyline for Chronic Low Back Pain

5 Oct, 2018 | 02:00h | UTC

Efficacy of Low-Dose Amitriptyline for Chronic Low Back Pain: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Low-dose antidepressants ease back pain – Australian Hospital + Healthcare Bulletin (free) AND Antidepressant Amitriptyline Might Help Ease Low Back Pain – Physician’s First Watch (free)

 


Study: Recovery of Walking after Complete Spinal Cord Injury

27 Sep, 2018 | 23:06h | UTC

Recovery of Over-Ground Walking after Chronic Motor Complete Spinal Cord Injury – New England Journal of Medicine (free)

Commentaries: Technology and therapy help individuals with chronic spinal cord injuries take steps – University of Louisville (free) AND Epidural Stimulation Helps Patients Walk After Total Paralysis – MedPage Today (free registration required) AND Paralyzed Patients Able to Walk Following Epidural Stimulation, Intense Rehab – Physician’s First Watch (free)

 


Study: Adverse Outcomes After Arthroscopic Partial Meniscectomy

27 Sep, 2018 | 22:59h | UTC

Adverse outcomes after arthroscopic partial meniscectomy: a study of 700 000 procedures in the national Hospital Episode Statistics database for England – The Lancet (free)

Invited Commentary: Potential harms of isolated arthroscopic partial meniscectomy (free)

Related: Needless procedures: knee arthroscopy is one of the most common but least effective surgeries – The Conversation (free) AND Arthroscopic surgery for degenerative knee arthritis and meniscal tears: a clinical practice guideline (free guideline and commentary)

 


Cohort Studies: Diclofenac Use and Cardiovascular Risks

6 Sep, 2018 | 03:04h | UTC

Diclofenac use and cardiovascular risks: series of nationwide cohort studies – The BMJ (free)

Commentary: Diclofenac Again Tied to Major Cardiovascular Events – NEJM Physician’s First Watch (free) AND ‘A major safety concern’: World’s most common NSAID doubles CVD risk – Cardiovascular Business (free)

 


Guideline: Management of Hip and Knee Osteoarthritis

31 Aug, 2018 | 02:31h | UTC

Guideline for the management of hip and knee osteoarthritis – Royal Australian College of General Practitioners (free PDF)

News Release: Updated osteoarthritis guideline designed to reduce unnecessary imaging and surgery (free)

Commentary: Australia hopes to reduce unnecessary imaging, surgery with updated osteoarthritis guidelines – Health Imaging (free)

““The Guideline for the management of knee and hip osteoarthritis,” offer up exercise and weight loss as a first line defense, and warn against costly treatments using glucosamine, opioids and arthroscopic surgery, said David Hunter, co-chair of the RACGP group responsible for the update.” (from Health Imaging)

 


Study: Mortality Effects of Timing Alternatives for Hip Fracture Surgery

11 Aug, 2018 | 02:38h | UTC

Mortality effects of timing alternatives for hip fracture surgery – Canadian Medical Association Journal (free)

Commentaries: Lower death rate when senior hip fractures are repaired quickly – Reuters (free) AND Delayed surgery for hip fractures cause of preventable deaths, study finds – The Globe and Mail (free) AND The sun should not set twice before hip fracture repair – CMAJ, via ScienceDaily (free)

 


Cohort Study: Risk Factors for Prosthetic Joint Infection After Hip Replacement

3 Aug, 2018 | 11:35h | UTC

Risk factors associated with revision for prosthetic joint infection after hip replacement: a prospective observational cohort study – The Lancet Infectious Diseases (free)

Commentaries: Risk factors in septic revisions following total hip arthroplasty – The Lancet Infectious Diseases (free) AND Several factors associated with hip replacement revision due to prosthetic joint infection – ACP Internist Weekly (free)

 


Study: Osteoporosis Treatment After Hip Fracture

26 Jul, 2018 | 18:37h | UTC

Association of Osteoporosis Medication Use After Hip Fracture With Prevention of Subsequent Nonvertebral Fractures: An Instrumental Variable Analysis – JAMA Network Open (free)

Commentaries: Osteoporosis Treatment After Hip Fracture: Bad News and Getting Worse – JAMA Network Open (free) AND Rate of Osteoporosis Drug Treatment to Prevent Recurrent Fractures Dropping – AJMC (free) AND Osteoporosis treatment often not started after hip fracture in elderly patients, study finds – ACP Internist (free)

 


Guideline: Diagnosis, Treatment and Prevention of Ankle Sprains

26 Jul, 2018 | 18:36h | UTC

Diagnosis, treatment and prevention of ankle sprains: update of an evidence-based clinical guideline – British Journal of Sports Medicine (free)

 


Randomized Trial: Subacromial Decompression vs Diagnostic Arthroscopy for Shoulder Impingement

20 Jul, 2018 | 03:28h | UTC

Subacromial decompression versus diagnostic arthroscopy for shoulder impingement: randomised, placebo surgery controlled clinical trial – The BMJ (free)

Commentary: Most common shoulder operation is no more beneficial than placebo surgery – University of Helsinki, via EurekAlert (free)

Related research with similar results: Arthroscopic subacromial decompression for subacromial shoulder pain (free article, editorial and commentaries)

 


Systematic Review: Negative Pressure Wound Therapy for Open Traumatic Wounds

13 Jul, 2018 | 02:31h | UTC

Negative pressure wound therapy for open traumatic wounds – Cochrane Library (free)

Summary: Negative pressure wound therapy for open traumatic wounds – Cochrane Library (free)

Related Research: Randomized Trial: Negative Pressure Wound Therapy No Better Than Regular Dressing in Severe Open Fracture of the Lower Limb (link to abstract and commentaries)

 


Overview of Guidelines for the Management of Non-Specific Low Back Pain in Primary Care

6 Jul, 2018 | 09:50h | UTC

Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview – European Spine Journal (free)

 


Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain

6 Jul, 2018 | 09:37h | UTC

Anticonvulsants in the treatment of low back pain and lumbar radicular pain: a systematic review and meta-analysis – Canadian Medical Association Journal (free)

Commentaries: Class of drugs used as alternative to opioids for back pain are ineffective, have potentially serious side effects: report – The Globe and Mail (free) AND Anticonvulsant drugs ineffective for low back pain and can cause harm, despite increased prescribing – CMAJ, via EurekAlert (free)

Related Meta-Analysis: Benefits and safety of gabapentinoids in chronic low back pain (free research and commentaries)

 


Guideline: Management of Osteoporosis and Fragility Fractures

29 Jun, 2018 | 03:16h | UTC

Guidelines for the management of osteoporosis and fragility fractures – Internal and Emergency Medicine (free)

Related Guidelines: UK clinical guideline for the prevention and treatment of osteoporosis – Archives of Osteoporosis (free) AND Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women: A Clinical Practice Guideline Update from the American College of Physicians – Annals of Internal Medicine (free)

 


USPSTF Statement: Screening for Osteoporosis to Prevent Fractures

29 Jun, 2018 | 02:52h | UTC

Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorials: Screening for Osteoporosis (free) AND Osteoporosis Screening—2 Steps May Be Too Much for Women Younger Than 65 Years (free)

Author Interview: USPSTF Recommendation Statement: Screening for Osteoporosis to Prevent Fractures (free)

See also: USPSTF Final Recommendation Statement (free)

 


Randomized Trial: More Weight Loss Associated with Better Outcomes in Knee Osteoarthritis

29 Jun, 2018 | 02:39h | UTC

Intentional Weight Loss for Overweight and Obese Knee Osteoarthritis Patients: Is More Better? – Arthritis Care & Research (free PDF)

Commentaries: Long-term weight loss of at least 20% helps improve outcomes in overweight, obese patients with knee osteoarthritis – ACP Internist (free) AND When it comes to weight loss in overweight and obese adults with knee osteoarthritis, more is better – Wiley, via ScienceDaily (free) AND More weight loss tied to less knee pain for obese people – Reuters (free) AND More Weight Loss Linked To Greater Decrease in Knee Arthritis Pain – MedicalResearch.com (free)

 


EULAR 2018: NSAIDs Account for Large Part of Osteoarthritis-CVD Link

22 Jun, 2018 | 02:50h | UTC

NSAIDs Account for Large Part of Osteoarthritis-CVD Link, Study Suggests – TCTMD (free)

 


Randomized Trial: Intramedullary Nail Fixation vs Locking Plate Fixation for Adults with a Fracture of the Distal Tibia

22 Jun, 2018 | 01:58h | UTC

Intramedullary nail fixation versus locking plate fixation for adults with a fracture of the distal tibia: the UK FixDT RCT – Health Technology Assessment (free) (via EvidenceAlerts)

 


Randomized Trial: Hip Arthroscopy vs Best Conservative Care for the Treatment of Femoroacetabular Impingement Syndrome

18 Jun, 2018 | 23:16h | UTC

Hip arthroscopy versus best conservative care for the treatment of femoroacetabular impingement syndrome (UK FASHIoN): a multicentre randomised controlled trial – The Lancet (free)

Commentaries: Hip arthroscopy: an evidence-based approach – The Lancet (free) AND New surgery for groin pain found to be more effective than physiotherapy – University of Warwick (free)

 


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