Oncology (all articles)
Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance
5 Mar, 2021 | 08:35h | UTCRecommendations: Pharmacovigilance Evidence Review: The effect of COVID-19 vaccines on breast screening – Drug Safety Research Unit
Related: 2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients
ACG Clinical Guidelines: Start colorectal cancer screening at 45
5 Mar, 2021 | 08:31h | UTCACG Clinical Guidelines: Colorectal Cancer Screening 2021 – The American Journal of Gastroenterology
Related: USPSTF draft statement now recommends starting colorectal cancer screening at 45
Global patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study
5 Mar, 2021 | 08:10h | UTCGlobal patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Global thyroid cancer overdiagnosis in children and adolescents – MDEdge (free registration required) AND Global Thyroid Cancer Overdiagnosis in Children and Adolescents – Medscape (free registration required)
Commentary on Twitter
New #IARCpaper shows the incidence of thyroid cancer in children & adolescents, a rare condition everywhere before 2000, has increased rapidly in recent years in many countries, & suggests overdiagnosis is likely to be the main driver of these increases https://t.co/1ct8iEJSty pic.twitter.com/JIjBBAyKNv
— IARC (@IARCWHO) January 20, 2021
RCT: Nivolumab plus Cabozantinib vs. Sunitinib for Advanced Renal-Cell Carcinoma
4 Mar, 2021 | 08:33h | UTCNivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma – New England Journal of Medicine (link to abstract – $ for full-text)
RCT: Effect of Blinatumomab vs. Chemotherapy in children with high-risk first-relapse B-Cell Acute Lymphoblastic Leukemia
3 Mar, 2021 | 08:19h | UTCEffect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)
Related study: Effect of Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy on Disease-Free Survival in Children, Adolescents, and Young Adults With First Relapse of B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Blinatumomab for Treatment of Children With High-risk Relapsed B-Cell Acute Lymphoblastic Leukemia – JAMA (free for a limited period)
Five-year outcomes from randomized, phase III trials: Nivolumab vs. Docetaxel in previously treated non–small-cell lung cancer
3 Mar, 2021 | 08:10h | UTC
Commentary on Twitter
At 5 years of follow up in CheckMate 017 and 057 trials, nivolumab continues to demonstrate a survival benefit vs docetaxel in patients with previously-treated advanced NSCLC https://t.co/oswZhdAPTW #JCO #lcsm #immunoonc pic.twitter.com/4FZJlfig99
— ASCO Publications (@ASCO_pubs) February 9, 2021
RCT: Extended vs. limited pelvic lymph node dissection during radical prostatectomy for intermediate- and high-risk prostate cancer
3 Mar, 2021 | 08:05h | UTCExtended Versus Limited Pelvic Lymph Node Dissection During Radical Prostatectomy for Intermediate- and High-risk Prostate Cancer: Early Oncological Outcomes from a Randomized Phase 3 Trial – European Urology (link to abstract – $ for full-text)
Commentary: Extended pelvic lymph node dissection during RP does not appear beneficial – Urology Times
Commentary on Twitter
Extended Versus Limited Pelvic Lymph Node Dissection During Radical Prostatectomy for Intermediate- and High-risk Prostate Cancer: Early Oncological Outcomes from a Randomized Phase 3 Trial#VisualAbstract https://t.co/7fAFlKmfTf@jeanlestingi @qdtrinh @RafaelFCoelho2 pic.twitter.com/es53WpXBFR
— European Urology (@EUplatinum) December 10, 2020
M-A: Local salvage therapies after radiotherapy for prostate cancer
3 Mar, 2021 | 08:06h | UTCA Systematic Review and Meta-analysis of Local Salvage Therapies After Radiotherapy for Prostate Cancer (MASTER) – European Urology (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
Pleased to share the results of our "MASTER" systematic review and meta-analysis of local salvage therapies for radioreccurent PCa @EUPlatinum https://t.co/23hy1UtNm5
— Amar Kishan (@AmarUKishan) December 11, 2020
New report reviews methods for reducing waste, improving efficiency with expensive injectable medications
28 Feb, 2021 | 21:29h | UTCOriginal report: Medications in Single Dose Vials: Implications of Discarded Drugs (2021) – National Academies of Sciences, Engineering, and Medicine
Commentary on Twitter
"significant amounts of expensive injectable or infused drugs, distributed in single-dose vials, are discarded" but hard to quantify.
Medications in Single-Dose Vials and Implications of Discarded Injectable Drugs: A National Academies Report https://t.co/z3ebKGIcEg
— Suresh Nirody (@snirody) February 26, 2021
2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients
28 Feb, 2021 | 21:42h | UTCCase series: Lymphadenopathy in COVID-19 Vaccine Recipients: Diagnostic Dilemma in Oncology Patients – Radiology
Related case series in women without cancer: Coronavirus Disease (COVID-19) Vaccination Associated Axillary Adenopathy: Imaging Findings and Follow-Up Recommendations in 23 Women – American Journal of Roentgenology
Related guidance 1: Multidisciplinary Recommendations Regarding Post-Vaccine Adenopathy and Radiologic Imaging: Radiology Scientific Expert Panel – Radiology
Related guidance 2: Mitigating the Impact of Coronavirus Disease (COVID-19) Vaccinations on Patients Undergoing Breast Imaging Examinations: A Pragmatic Approach – American Journal of Roentgenology AND Commentary: What to do when a mammogram shows swollen lymph nodes in women just vaccinated for COVID – Massachusetts General Hospital
Commentary: COVID-19 vaccine affects imaging results, researchers warn – AuntMinnie (free registration required)
RCT: Endoscopic surgery improves survival compared with intensity-modulated radiotherapy in resectable locally recurrent nasopharyngeal carcinoma
28 Feb, 2021 | 20:45h | UTC
CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma
26 Feb, 2021 | 08:31h | UTCOriginal study: Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma – New England Journal of Medicine
Integrated palliative and oncology care for patients receiving treatment for acute myeloid leukemia
26 Feb, 2021 | 08:25h | UTCOriginal article: Effectiveness of Integrated Palliative and Oncology Care for Patients With Acute Myeloid Leukemia: A Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Randomized trial: Oral Azacitidine maintenance therapy for acute myeloid leukemia in first remission
26 Feb, 2021 | 08:23h | UTCOral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Maintenance Oral Azacitidine for Patients With AML in First Remission: QUAZAR AML-001 Trial – The ASCO Post
ASCO Guideline: Management of dyspnea in advanced cancer
24 Feb, 2021 | 02:10h | UTCManagement of Dyspnea in Advanced Cancer: ASCO Guideline – Journal of Clinical Oncology
Commentary on Twitter (thread – click for more)
1/ How can we better manage dyspnea in people with advanced cancer?
Wonderful to see this new @ASCO Guideline out.
Led by Drs. @DrDavidHui and @campbell_meg #supponc #pallonc
Full text: https://t.co/qbdhzbibKw pic.twitter.com/f2Qf6GswvK
— Arjun Gupta (@guptaarjun90) February 23, 2021
SR: Delays and disruptions in cancer health care due to COVID-19 pandemic
24 Feb, 2021 | 02:46h | UTCCommentary: COVID-19 Pandemic Caused Delays in Cancer Care – DocWire News
Commentary on Twitter
Delays & Disruptions in #Cancer HealthCare Due to #COVID19 Pandemic – A health system Perspective:
Interruptions & disruptions in:
?77%, facility-level
?79%, supply chain
?60%, personnel availabilityFind more from @FroitbergM at:https://t.co/wGtpNW5Zrm@ASCO_pubs ?? pic.twitter.com/R3jlzAsfRG
— Dario Trapani (@darioT_) February 23, 2021
Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers
24 Feb, 2021 | 02:00h | UTC
Guidelines in the management of CNS tumors
23 Feb, 2021 | 01:09h | UTCGuidelines in the management of CNS tumors – Journal of Neuro-Oncology
Clinical practice guidelines for BRCA1 and BRCA2 genetic testing
21 Feb, 2021 | 21:43h | UTCClinical practice guidelines for BRCA1 and BRCA2 genetic testing – European Journal of Cancer
Commentary on Twitter
BRCA1 and BRCA2 genetic testing- Clinical practice guidelineshttps://t.co/bpdXf70PnW pic.twitter.com/i6O0br35ap
— K Pavithran (@drkpavithran) February 15, 2021
Initial management of noncastrate advanced, recurrent, or metastatic prostate cancer: ASCO guideline update
21 Feb, 2021 | 21:47h | UTC
Review: Diagnosis and treatment of metastatic colorectal cancer
19 Feb, 2021 | 02:07h | UTCDiagnosis and Treatment of Metastatic Colorectal Cancer: A Review – JAMA (free for a limited period)
Therapy for Stage IV Non–Small-Cell Lung Cancer With Driver Alterations: ASCO and OH (CCO) Joint Guideline Update
19 Feb, 2021 | 02:04h | UTC
Review: Optimal supportive care for patients with metastatic breast cancer according to their disease progression phase
18 Feb, 2021 | 02:35h | UTC
RCT: Cemiplimab monotherapy for first-line treatment of advanced non-small-cell lung cancer with PD-L1 of at least 50%
18 Feb, 2021 | 02:34h | UTC
Commentary on Twitter
Phase 3 trial suggests #cemiplimab could be used as new first-line monotherapy option for patients with advanced non-small-cell #lungcancer with PD-L1 of at least 50%—it improved overall & progression-free survival compared with chemotherapy. Read https://t.co/O06Of6wx07 pic.twitter.com/KtQ24lEoR5
— The Lancet (@TheLancet) February 17, 2021
Review: Breast cancer in adolescent and young adult women under the age of 40 years
17 Feb, 2021 | 01:13h | UTCBreast Cancer in Adolescent and Young Adult Women Under the Age of 40 Years – JCO Oncology Practice