Oncology (all articles)
Addressing palliative care and end-of-life issues in patients with advanced cancer: a systematic review of communication interventions for physicians not specialized in palliative care.
20 Jul, 2022 | 11:40h | UTC
RCT | Doxorubicin alone vs. doxorubicin with trabectedin followed by trabectedin alone as first-line therapy for metastatic or unresectable leiomyosarcoma.
20 Jul, 2022 | 11:36h | UTCDoxorubicin alone versus doxorubicin with trabectedin followed by trabectedin alone as first-line therapy for metastatic or unresectable leiomyosarcoma (LMS-04): a randomised, multicentre, open-label phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Phase 2 RCT | Deintensified chemoradiotherapy for pretreatment Epstein-Barr Virus DNA-selected low-risk locoregionally advanced nasopharyngeal carcinoma.
19 Jul, 2022 | 12:58h | UTCDeintensified Chemoradiotherapy for Pretreatment Epstein-Barr Virus DNA-Selected Low-Risk Locoregionally Advanced Nasopharyngeal Carcinoma: A Phase II Randomized Noninferiority Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentaries:
Commentary on Twitter
Less is more? ? 2-cycle cisplatin concurrent chemoradiotherapy is not inferior to 3-cycles based on 3-yr PFS in treating locoregionally advanced nasopharyngeal ca w/preRX EBV DNA levels < 4000.QOL & toxicity improved w/ less chemo https://t.co/XovHi2P06W pic.twitter.com/JJqiC8wnWW
— Journal of Clinical Oncology (@JCO_ASCO) January 25, 2022
Network M-A | Comparative effectiveness and risk of preterm birth of local treatments for cervical intraepithelial neoplasia and stage IA1 cervical cancer.
18 Jul, 2022 | 11:27h | UTC
Commentary on Twitter
Online first: Comparative effectiveness and risk of #preterm #birth of local #treatments for #cervicalintraepithelialneoplasia and stage IA1 #cervicalcancer: a systematic review and network meta-analysis https://t.co/APwtqyXJKO pic.twitter.com/GYuoroxRmw
— The Lancet Oncology (@TheLancetOncol) July 12, 2022
Using circulating tumor DNA in colorectal cancer: current and evolving practices.
18 Jul, 2022 | 10:51h | UTC
A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation.
15 Jul, 2022 | 12:55h | UTCA guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation – Journal of Thoracic Disease
Part 1 – A guide to decision-making
Part 2 – Systematic review of evidence regarding resection extent in generally healthy patients
Part 3 – Systematic review of evidence regarding surgery in compromised patients or specific tumors
Part 4 – Systematic review of evidence involving SBRT and ablation
Guidelines on germline testing for urologic tumor syndromes.
15 Jul, 2022 | 12:49h | UTCGuidelines on Germline Testing for Urologic Tumor Syndromes – European Urology Focus
Phase 2 RCT | Efficacy of preoperative mFOLFIRINOX vs. mFOLFIRINOX plus hypofractionated radiotherapy for borderline resectable adenocarcinoma of the pancreas.
15 Jul, 2022 | 12:29h | UTCEfficacy of Preoperative mFOLFIRINOX vs mFOLFIRINOX Plus Hypofractionated Radiotherapy for Borderline Resectable Adenocarcinoma of the PancreasThe A021501 Phase 2 Randomized Clinical Trial – JAMA Oncology (free for a limited period)
Editorial: The Continued Struggle for Defining a Role for Radiotherapy in Pancreas Cancer – JAMA (free for a limited period)
Commentary on Twitter
Ph 2 trial of 126 pts w/borderline resectable pancreatic ductal adenoCa shows 18 mo OS after neoadjuvant mFOLFIRINOX of 66.7%, favorable vs. historical data; 18m OS if mFOLFORINOX then hypofract RT is 47.3%, if chemo then pancreatectomy is 87.5%. https://t.co/wOMNrTOAzm
— JAMA Oncology (@JAMAOnc) July 14, 2022
M-A of RCTs | Megestrol Acetate not beneficial for cancer-related anorexia/cachexia.
14 Jul, 2022 | 12:50h | UTC
The EBMT nursing guidelines on CAR-T Therapy | A framework for patient care and managing common toxicities.
14 Jul, 2022 | 12:45h | UTC
How to treat renal cell carcinoma: the current treatment landscape and cardiovascular toxicities.
14 Jul, 2022 | 12:35h | UTC
Randomized crossover trial | AI reduces miss rate of precancerous polyps in colorectal cancer screening.
14 Jul, 2022 | 12:29h | UTCNews Release: AI reduces miss rate of precancerous polyps in colorectal cancer screening – Mayo Clinic
Original Study: Impact of Artificial Intelligence on Miss Rate of Colorectal Neoplasia – Gastroenterology
Prevalence of cardiovascular disease in patients with potentially curable malignancies: a national registry dataset analysis.
14 Jul, 2022 | 12:33h | UTC
The Global Retinoblastoma Outcome Study | A prospective, cluster-based analysis of 4,064 patients from 149 countries.
14 Jul, 2022 | 12:16h | UTCInvited Commentary: Retinoblastoma as a lens for correctable disparities worldwide – The Lancet Global Health
M-A | Risk of developing gallbladder cancer in patients with gallbladder polyps detected on Trans-Abdominal ultrasound.
14 Jul, 2022 | 12:14h | UTCRisk of developing gallbladder cancer in patients with gallbladder polyps detected on Trans-Abdominal ultrasound: a systematic review and Meta-Analysis – British Journal of Radiology (link to abstract – $ for full-text)
Related:
Critical Analysis of the Updated Guidelines for Management of Gallbladder Polyps – Annals of Surgical Oncology (if the link is paywalled, try this one)
RCT | Gemcitabine vs. Nab-paclitaxel combined with cisPlatin as first-line treatment in patients with metastatic triple-negative breast cancer.
14 Jul, 2022 | 12:10h | UTC
Commentary on Twitter
Gemcitabine or nab-paclitaxel in combination with cisplatin as first-line treatment in patients with metastatic triple-negative breast cancer: results of a randomized phase 3 trial.https://t.co/RKZYdLRbHq#CancerResearch @natrescancer pic.twitter.com/CrCOCJ2HMu
— Nature Communications (@NatureComms) July 13, 2022
ESMO recommendations on the use of circulating tumor DNA assays for patients with cancer.
13 Jul, 2022 | 11:38h | UTC
Genetic testing in prostate cancer management: considerations informing primary care.
13 Jul, 2022 | 11:25h | UTC
Female erectile tissues and sexual dysfunction after pelvic radiotherapy: a scoping review.
13 Jul, 2022 | 11:23h | UTC
Modern developments in germline pharmacogenomics for oncology prescribing.
13 Jul, 2022 | 11:21h | UTC
Phase II RCT | Proton craniospinal irradiation vs. photon involved-field radiotherapy for patients with solid tumor leptomeningeal metastasis.
13 Jul, 2022 | 11:09h | UTCRandomized Phase II Trial of Proton Craniospinal Irradiation Versus Photon Involved-Field Radiotherapy for Patients With Solid Tumor Leptomeningeal Metastasis – Journal of Clinical Oncology (link to abstract – $ for full-text)
ASCO Living Guideline | Therapy for stage IV non–small-cell lung cancer with driver alterations.
12 Jul, 2022 | 12:46h | UTC
Commentary on Twitter
Just published in #JCO: ? Updated recommendations on therapy for stage IV #NSCLC with driver alterations by @ns_chd et al ? https://t.co/JzrxEey4Si #lungcancer #lcsm pic.twitter.com/CFPTJIkrhK
— Journal of Clinical Oncology (@JCO_ASCO) July 11, 2022
ASCO Living Guideline | Therapy for stage IV non–small-cell lung cancer without driver alterations.
12 Jul, 2022 | 12:44h | UTC
Commentary on Twitter
Now available in #JCO: Key updated first-line recommendations on therapy for stage IV #NSCLC ? without driver alterations by @ns_chd et al. ➡️ https://t.co/KovrwEtYGz #lungcancer #lcsm pic.twitter.com/iQONRkgxsj
— Journal of Clinical Oncology (@JCO_ASCO) July 11, 2022
M-A | Does it really pay-off? Comparison of lymphadenectomy versus observational approach in skin melanoma with positive sentinel node biopsy.
12 Jul, 2022 | 12:37h | UTC
RCT | Weekly dose-dense chemotherapy in first-line epithelial ovarian, fallopian tube, or primary peritoneal cancer treatment.
12 Jul, 2022 | 11:51h | UTC
Commentary on Twitter
Updated results from the phase III ICON8 trial in 1,566 pts with newly diagnosed stage IC–IV epithelial ovarian, peritoneal or fallopian tube carcinoma reveal no statistically significant difference in OS with 3-weekly vs weekly carboplatin & paclitaxel: https://t.co/czgH7uGxjt
— NatureRevClinOncol (@NatRevClinOncol) June 15, 2022