Oncology (all articles)
ASCO Guideline on Castrate-Resistant Prostate Cancer
3 May, 2017 | 17:23h | UTCSource: ASCO Issues Guideline on Castrate-Resistant Prostate Cancer – Medscape (free registration required)
Adjuvant Systemic Therapy and Adjuvant Radiation Therapy for Stage I to IIIA Completely Resected Non–Small-Cell Lung Cancers
1 May, 2017 | 16:48h | UTC
Standardized Criteria for Palliative Care Consultation
24 Apr, 2017 | 15:25h | UTCProspective, before-after cohort study: Standardized Criteria for Palliative Care Consultation on a Solid Tumor Oncology Service Reduces Downstream Health Care Use – Journal of Oncology Practice (free)
Editorial: Making the Right Thing Easier to Do: Standardized Integration of Oncology and Palliative Care – Journal of Oncology Practice (free)
Related Guideline: Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update (free)
Commentaries on the study: Standardized Palliative Care Consults Cut Cancer Readmissions – Also, less chemotherapy after discharge – MedPage Today (free registration required) AND Standardized Cancer Palliative Care Consults Linked to Stronger Home-Based Support – AJMC (free)
Patients with at least one of the following 4 criteria: 1) advanced solid tumor; 2) prior hospitalization within 30 days; 3) hospitalization > 7 days; or 4) active symptoms – received automatic palliative care consultation. The rates of 30-day readmissions dropped from 35% to 18% and chemotherapy after discharge dropped from 44% to 18%.
Non-Small Cell Lung Cancer – NCCN Guideline
18 Apr, 2017 | 14:07h | UTCNon-Small Cell Lung Cancer – NCCN Clinical Practice Guidelines in Oncology (free)
New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management
18 Apr, 2017 | 14:05h | UTCSource: Critical Care Reviews Newsletter
Life after breast, prostate, and colon cancer: Primary care’s role
17 Apr, 2017 | 13:53h | UTC
Recorded childhood cancers rise by 13% worldwide
14 Apr, 2017 | 16:11h | UTCRecorded childhood cancers rise by 13% worldwide, study finds – The Guardian (free)
Original articles: International incidence of childhood cancer, 2001–10: a population-based registry study – The Lancet Oncology (free) ANDWorldwide comparison of survival from childhood leukaemia for 1995–2009, by subtype, age, and sex (CONCORD-2): a population-based study of individual data for 89 828 children from 198 registries in 53 countries – The Lancet Haematology (free) Related commentary: Issues raised by the incidence and survival of childhood cancers (free)
ASCO has just published 3 guidelines on the management of pancreatic cancer
14 Apr, 2017 | 16:13h | UTCASCO has just published 3 guidelines on the management of pancreatic cancer:
1 – Potentially Curable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update (free) AND 2 – Metastatic Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline Summary (free) AND 3 – Locally Advanced Unresectable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline Summary (free)
Screening to Prevent Invasive Cervical Cancer Guideline
13 Apr, 2017 | 16:03h | UTCScreening to Prevent Invasive Cervical Cancer: ASCO Resource-Stratified Clinical Practice Guideline (free)
“The ASCO guidelines outline the minimum standards for HPV-based screening for each resource strata; additional and more frequent screening may be added as the resources become available”.
Childhood cancers: 2 new studies on international incidence and survival
13 Apr, 2017 | 16:05h | UTCChildhood cancers: 2 new studies on international incidence and survival (RT @TheLancet see Tweet)
Childhood cancer: International incidence of childhood cancer, 2001–10: a population-based registry study – The Lancet Oncology (free)
Childhood leukemia: Worldwide comparison of survival from childhood leukaemia for 1995–2009, by subtype, age, and sex (CONCORD-2): a population-based study of individual data for 89 828 children from 198 registries in 53 countries – The Lancet Haematology (free)
Related commentary: Issues raised by the incidence and survival of childhood cancers (free)
Prostate Cancer Screening – Conflicting views on the new USPSTF draft recommendations
13 Apr, 2017 | 16:06h | UTCProstate Cancer Screening – Conflicting views on the new USPSTF draft recommendations
In favor of screening: New Official Prostate Cancer Screening Guidelines Announced: Too Little, Too Late? – Forbes (free) AND Federal Task Force Softens Opposition To Routine Prostate Cancer Screening – NPR
Against screening: The new recommendations for prostate cancer screenings are a bad deal – STAT News (free)
See also: Original USPSTF draft recommendations and related commentaries in yesterday’s issue
Potentially Curable Pancreatic Cancer Guideline
13 Apr, 2017 | 16:02h | UTCDue to a recent study showing a 2,5 month increase in median overall survival, the doublet regimen of gemcitabine and capecitabine seems to be preferred in the absence of concerns for toxicity or tolerance.
Emergencies in Hematology and Oncology
11 Apr, 2017 | 15:45h | UTCEmergencies in Hematology and Oncology – Mayo Clinic Proceedings (free)
Comprehensive review covering the most common oncological emergencies.
Cancer patients have 55% greater risk of suicide
6 Apr, 2017 | 15:05h | UTCCancer patients have 55% greater risk of suicide, study finds – The Guardian (free) (RT @ghn_news)
Can low-dose aspirin can reduce risk of death from cancer?
6 Apr, 2017 | 15:07h | UTCLow-dose aspirin can reduce risk of death from cancer, research says – CNN (free)
Not so fast: CNN claims aspirin can reduce cancer death risk, falling into observational study trap – HealthNewsReviews (free)
See also: Final Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer – U.S. Preventive Services Task Force (free)
American College of Radiology (ACR) Appropriateness Criteria Adds Topics
4 Apr, 2017 | 21:19h | UTCACR Appropriateness Criteria Adds Topics, Covers More Clinical Variants Than Ever Before (free)
Browse Appropriateness Criteria Topics (free)
Source: Newswise
This comprehensive guide from American College of Radiology (ACR) covers 230 topics with more than 1,100 clinical indications and has just been updated. It is a very useful resource for doctors in all specialties to guide which exam is most appropriate in each clinical situation.
Prevention of everolimus-related stomatitis
30 Mar, 2017 | 17:24h | UTCPrevention of everolimus-related stomatitis in women with hormone receptor-positive, HER2-negative metastatic breast cancer using dexamethasone mouthwash (SWISH): a single-arm, phase 2 trial – The Lancet Oncology (link to abstract – $ required for full-text)
See also: SWISH Four Times a Day to Keep Oral Mucositis Away – Medscape (free registration required)
This simple and inexpensive treatment resulted in a more than ten-times reduction in the incidence of grade 2 or higher stomatitis.
I have cancer. This comic shows how much pressure I feel to be a hero
29 Mar, 2017 | 17:10h | UTCI have cancer. This comic shows how much pressure I feel to be a hero – VOX (free)
Source: STAT Newsletter
Interesting read…
Adverse Effects of Prostate Cancer Treatments
27 Mar, 2017 | 00:48h | UTCAdverse Effects of Prostate Cancer Treatments Vary – MedPage Today (free registration required)
Study 1 – Link to abstract ($ required for full-text): Association Between Radiation Therapy, Surgery, or Observation for Localized Prostate Cancer and Patient-Reported Outcomes After 3 Years – JAMA
Study 2 – Link to abstract ($ required for full-text): Association Between Choice of Radical Prostatectomy, External Beam Radiotherapy, Brachytherapy, or Active Surveillance and Patient-Reported Quality of Life Among Men With Localized Prostate Cancer – JAMA
HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma
27 Mar, 2017 | 00:53h | UTCSource: EvidenceAlerts (free registration required)