Oncology (all articles)
Breast Implant-Associated Anaplastic Large Cell Lymphoma
23 Mar, 2018 | 02:42h | UTCFDA In Brief: FDA updates public information about known risk of lymphoma from breast implants (free) AND Breast Implant-Associated Anaplastic Large Cell Lymphoma – FDA Update (free)
Commentaries: More Cases Are Reported of Unusual Cancer Linked to Breast Implants – The New York Times (10 articles per month are free) AND Implant-Related Lymphoma Cases Rise – More than 400 cases reported to FDA – MedPage Today (free)
“Some 400 to 500 women worldwide have an unusual type of lymphoma linked to breast implants with textured surfaces. Experts say women considering implants should be told”. (via @NYTHealth see Tweet)
Research: Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer
23 Mar, 2018 | 02:00h | UTCHelicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: H. pylori Treatment for Gastric Cancer Prevention (free)
Commentary: H pylori Eradication Benefits Patients With Early Gastric Cancer – Medscape (free registration required)
Screening for Skin Cancer: US Preventive Services Task Force Recommendation Statement
23 Mar, 2018 | 01:58h | UTCScreening for Skin Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)
Related Recommendation Statement: Behavioral Counseling to Prevent Skin Cancer: US Preventive Services Task Force (free)
JAMA Editorials: Sun Protection and Skin Self-examination and the US Preventive Services Task Force Recommendation on Behavioral Counseling for Skin Cancer Prevention (free) AND Should Pediatricians Be More Proactive in Counseling Children About Skin Cancer Risk? Implications of the USPSTF Recommendation Statement (free) AND The Potential of Behavioral Counseling to Prevent Skin Cancer (free) AND USPSTF Recommendations for Behavioral Counseling for Skin Cancer Prevention: Throwing Shade on UV Radiation (free) AND The Value of Behavioral Counseling for Skin Cancer Prevention: Actions We Can Take Now and Guidance for the Future (free)
Author Interviews: Screening for Skin Cancer (free audio) AND USPSTF Recommendation: Behavioral Counseling to Prevent Skin Cancer (free)
Commentaries: Doctors endorse counseling of some kids, young adults to prevent skin cancer – Reuters (free) AND Evidence insufficient to make recommendation regarding visual skin examination by a clinician – The JAMA Network, via EurekAlert (free)
Research: Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors
23 Mar, 2018 | 01:56h | UTCCommentaries: Survivors of childhood cancer are at great risk of heart problems in adulthood – eCancerNews (free) AND Higher heart risk for survivors of childhood cancer – OnMedica (free)
Related study: The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE) – The Lancet (link to abstract – $ for full-text)
Related Guidelines and Reviews: Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines (free) AND Canadian Cardiovascular Society Guidelines for Evaluation and Management of Cardiovascular Complications of Cancer Therapy (free) AND Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management – CA: A Cancer Journal for Clinicians (free)
Research: MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis
23 Mar, 2018 | 01:53h | UTCMRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis – New England Journal of Medicine (free)
Commentaries: Prostate MRI reveals more treatable cancers, reduces overdiagnosis than standard biopsy – European Urology Association, via EurekAlert (free) AND MRI Before Biopsy Better Than TRUS in Prostate Cancer – Medscape (free registration required)
Research: Physical activity, sedentary behaviour and colorectal cancer risk
23 Mar, 2018 | 01:51h | UTCPhysical activity, sedentary behaviour and colorectal cancer risk in the UK Biobank – British Journal of Cancer (link to abstract – $ for full-text)
Commentaries: Binge watching TV could increase bowel cancer risk in men – Imperial College London (free) AND Expert reaction to study on physical activity, sedentary behaviour and bowel cancer risk – Science Media Centre (free)
Meta-analysis: Immune-related adverse events for anti-PD-1 and anti-PD-L1 drugs
22 Mar, 2018 | 23:51h | UTC
Research: Effect of Standard vs Dose-Escalated Radiation Therapy for Patients With Intermediate-Risk Prostate Cancer
22 Mar, 2018 | 23:48h | UTCEffect of Standard vs Dose-Escalated Radiation Therapy for Patients With Intermediate-Risk Prostate Cancer: The NRG Oncology RTOG 0126 Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Commentaries: Higher doses of radiation don’t improve survival in prostate cancer: Side effects also a concern – Washington University School of Medicine, via ScienceDaily (free) AND Higher doses of radiation don’t improve overall survival for prostate cancer patients – OnMedica (free)
Review: Neoplastic meningitis in solid tumors
22 Mar, 2018 | 23:32h | UTC
Research: Carvedilol for Prevention of Chemotherapy Related Cardiotoxicity
16 Mar, 2018 | 03:38h | UTC#ACC18 – Carvedilol for Prevention of Chemotherapy Related Cardiotoxicity – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Beta Blocker Shows Mixed Results in Protecting Against Chemo-Induced Heart Damage – American College of Cardiology (free) AND Carvedilol Effect in Preventing Chemotherapy Induced CardiotoxicitY – CECCY – American College of Cardiology (free)
Related study from #ACC18: Heart Drugs Prevented Cardiotoxicity in Breast Cancer Treated With Anthracycline and Trastuzumab – American College of Cardiology (free)
“According to the CECCY trial, carvedilol had no effect on left ventricular function in breast cancer patients treated w/ doxorubicin, but did result in a reduction in troponin I levels & diastolic dysfunction”. (via @ACCinTouch see Tweet)
Research: Vitamin D and risk of total and site specific cancers
16 Mar, 2018 | 03:26h | UTC“Wake me up when there is a positive randomized trial of vitamin D pills for anything” (from Richard Lehman’s review).
NCCN Guideline: Hodgkin Lymphoma
16 Mar, 2018 | 01:35h | UTCNCCN Guidelines Insights: Hodgkin Lymphoma, Version 1.2018 (free)
NCCN Guideline: Breast Cancer
16 Mar, 2018 | 01:35h | UTCBreast Cancer, Version 4.2017, NCCN Clinical Practice Guidelines in Oncology (free)
Guideline: Radiation Therapy for the Whole Breast
16 Mar, 2018 | 01:24h | UTCCommentary: ASTRO issues clinical guideline for whole breast radiation therapy – eCancer News (free)
Research: Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality
8 Mar, 2018 | 22:07h | UTCEffect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: One-off PSA screening for prostate cancer does not save lives – eCancer News (free)
“Largest ever prostate cancer trial – CAP – published in the JAMA. No effect from low intensity PSA screening on prostate cancer mortality at 10 years”. (via @KariTikkinen see Tweet)
Cancer screening recommendations: an international comparison of high income countries
8 Mar, 2018 | 22:02h | UTCCancer screening recommendations: an international comparison of high income countries – Public Health Reviews (free) (via @hildabast see Tweet)
NCCN’s cancer treatment guidelines questioned
8 Mar, 2018 | 22:02h | UTCCommentaries: Vinay Prasad on the NCCN’s cancer treatment guidelines: The US system needs an audit – The BMJ Opinion (free) AND US cancer network recommending expensive drugs based on weak evidence, study finds – The Guardian (free) AND New Study Questions Evidence for NCCN Recommendations – Medscape (free registration required)
Reducing Overtreatment of Cancer With Precision Medicine
8 Mar, 2018 | 20:42h | UTCReducing Overtreatment of Cancer With Precision Medicine: Just What the Doctor Ordered – JAMA (free for a limited period)
NCCN Guideline: T-Cell Lymphomas
8 Mar, 2018 | 20:30h | UTCNCCN Guidelines Insights: T-Cell Lymphomas, Version 2.2018 (free)
Meta-Analysis: The effect of exercise on cancer-related fatigue in cancer survivors
8 Mar, 2018 | 20:15h | UTC
Guideline: Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy
2 Mar, 2018 | 02:04h | UTCRelated guidelines: Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients: guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) (free) AND Management of febrile neutropaenia: ESMO Clinical Practice Guidelines (free) AND Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update (free)
Meta-Analysis: Clinical course of untreated cervical intraepithelial neoplasia grade 2 under active surveillance
2 Mar, 2018 | 01:51h | UTCEditorial: Treatment or surveillance for CIN2? (free)
Commentaries: Treatment or surveillance for CIN2: when less is more – The BMJ Opinion (free) AND Some irregular cervical lesions could be monitored rather that treated immediately – OnMedica (free) AND Regular monitoring rather than immediate treatment justified for some cervical lesions – EurekAlert (free)
Research: Nut Consumption and Survival in Patients With Stage III Colon Cancer
2 Mar, 2018 | 01:32h | UTCNut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance) – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentaries: Nut Consumption May Aid Colon Cancer Survival – Yale Cancer Center, via NewsWise (free) AND Nuts, Especially Tree Nuts, and Improved CRC Survival – Medscape (free registration required
A survival benefit was suggested by this observational trial.
Review: Cancer Diagnosis in Patients with Heart Failure
2 Mar, 2018 | 01:24h | UTCRelated Guidelines and Reviews: Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines (free) AND Canadian Cardiovascular Society Guidelines for Evaluation and Management of Cardiovascular Complications of Cancer Therapy (free) AND Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management – CA: A Cancer Journal for Clinicians (free)
Patient led PROMs must take centre stage in cancer research
1 Mar, 2018 | 22:05h | UTCPatient led PROMs must take centre stage in cancer research – Research Involvement and Engagement (free) (via @RichardLehman1 see Tweet)