Oncology (all articles)
ASCO 2018: Many Women with Early-Stage Breast Cancer Can Forgo Chemotherapy When Guided by a 21-Gene Expression Assay
7 Jun, 2018 | 02:23h | UTCCommentaries: 2018 ASCO: TAILORx: Most Women With Early-Stage Breast Cancer Can Forgo Chemotherapy When Guided by a Diagnostic Test – The ASCO Post (free) AND Many breast cancer patients can skip chemo, big study finds – STAT (free) AND Many women with early-stage breast cancer can skip chemotherapy: study – Reuters (free) AND For Some Breast Cancer Patients, The Chemo Decision Just Got Easier – NPR (free) AND Breast cancer: Test means fewer women will need chemotherapy – BBC (free) AND Good News for Women With Breast Cancer: Many Don’t Need Chemo – The New York Times (10 articles per month are free)
ASCO 2018: Pembrolizumab vs. Chemotherapy as First-line Therapy for Advanced Non-Small Cell Lung Cancer
7 Jun, 2018 | 02:20h | UTCCommentaries: 2018 ASCO: KEYNOTE-042 Trial Compares Pembrolizumab With Chemotherapy as First-Line Treatment of NSCLC With PD-L1 Expression of 1% or More – The ASCO Post (free) AND ‘End of an Era’ for Chemo in Non-Small Cell Lung Cancer – Medscape (free registration required)
ASCO 2018: Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma
7 Jun, 2018 | 02:21h | UTCEditorial: Cytoreductive Nephrectomy — Patient Selection Is Key (free)
Commentaries: 2018 ASCO: Carmena Trial Compares Nephrectomy Plus Adjuvant Sunitinib vs Sunitinib Alone in Metastatic RCC – The ASCO Post (free) AND In Advanced Kidney Cancer, Surgery No Longer Sole Standard of Care – Medscape (free registration required)
ASCO 2018: Low-Dose Maintenance Chemotherapy in Rhabdomyosarcoma
7 Jun, 2018 | 02:16h | UTCLow-Dose Maintenance Chemotherapy in Rhabdomyosarcoma – The ASCO Post (free)
Research: Affordability and Price Increases of New Cancer Drugs in Clinical Guidelines
7 Jun, 2018 | 02:18h | UTCAffordability and Price Increases of New Cancer Drugs in Clinical Guidelines, 2007–2016 – Cancer Spectrum (free) (via @oncology_bg see Tweet)
ASCO 2018: Ibrutinib plus Rituximab in Waldenström’s Macroglobulinemia
7 Jun, 2018 | 02:19h | UTCCommentary: Ibrutinib/Rituximab Improves PFS in Waldenström’s Macroglobulinemia – ASCO Daily News (free)
Editorial: Marketing Personalized Cancer Treatments Requires Careful Language
7 Jun, 2018 | 02:17h | UTCMarketing personalized cancer treatments requires careful language – Nature (free)
Related: What Precisely Is Precision Oncology—and Will It Work? – The ASCO Post (free) AND Hope and hype around cancer immunotherapy – CNN (free)
“Therapies tailored to individual tumors must not be oversold”.
ASCO 2018: Blood Test Shows Potential as a Detection Tool for Early-Stage Lung Cancer
7 Jun, 2018 | 02:15h | UTCBlood Test Shows Potential as a Detection Tool for Early-Stage Lung Cancer – The ASCO Post (free)
Commentary: Biotech Firm Grail Takes The First Steps In Its Quest For A Blood Test For Cancer – Forbes (free) AND Questions about a ‘simple blood test’ to screen for cancer prompt revealing answer: It’s complicated – Health News Review (free)
Systematic Review: Stent Placement vs. Surgical Palliation in Malignant Gastric Outlet Obstruction
6 Jun, 2018 | 21:50h | UTCSummary: Stent placement versus surgery to control symptoms of a blocked stomach outlet caused by inoperable cancer – Cochrane Library (free)
AUA/ASTRO/SUO Guideline: Clinically Localized Prostate Cancer
6 Jun, 2018 | 21:49h | UTCPart I: Risk Stratification, Shared Decision Making, and Care Options – The Journal of Urology (free)
Part II: Recommended Approaches and Details of Specific Care Options – The Journal of Urology (free)
Randomized Trial: Once-a-Week vs Once-Every-3-Weeks Cisplatin Chemoradiation for Locally Advanced Head and Neck Cancer
6 Jun, 2018 | 21:47h | UTCCommentary: Once-Weekly vs Every-3-Week Cisplatin Chemoradiation in Locally Advanced Head and Neck Cancer – The ASCO Post (free)
ASCO 2018: Some Patients With Prostate Cancer Have Good Results With Immunotherapy
6 Jun, 2018 | 21:37h | UTCCommentaries: First Major Trial Of Keytruda For Prostate Cancer Shows It Works, But Only For A Minority Of Men – Forbes (free)
ASCO 2018: Matching Treatment to Genetic Changes in the Tumor Improves Survival Across Multiple Cancer Types
6 Jun, 2018 | 21:31h | UTC
Updates in the Evaluation and Management of Breast Cancer
6 Jun, 2018 | 21:27h | UTCUpdates in the Evaluation and Management of Breast Cancer – Mayo Clinic Proceedings (free)
Things We Do For No Reason: Neutropenic Diet
1 Jun, 2018 | 04:37h | UTCThings We Do For No Reason: Neutropenic Diet – Journal of Hospital Medicine (free) (via @guptaarjun90 and @AnilMakam)
Man vs. Machine: Diagnostic Performance of AI for Melanoma Recognition
1 Jun, 2018 | 04:23h | UTCCommentaries: AI surpasses dermatologists at diagnosing skin cancer – ESMO, via eCancer News (free) AND Computer learns to detect skin cancer more accurately than doctors – The Guardian (free) AND A.I. better at diagnosing skin cancer than humans – OnMedica (free)
Cohort Study: Lifetime Smoking History and Risk of Lung Cancer
1 Jun, 2018 | 04:14h | UTCLifetime Smoking History and Risk of Lung Cancer: Results From the Framingham Heart Study – Journal of the National Cancer Institute (link to abstract – $ for full-text)
Commentaries: Risk of Incident Lung Cancer Drops by 39% Five Years After Smokers Quit – AJMC (free) AND New research finds lung cancer risk drops substantially within five years of quitting – Vanderbilt University Medical Center, via eCancer News (free)
Guideline: Colorectal Cancer Screening for Average‐risk Adults
1 Jun, 2018 | 03:45h | UTCNews Release: American Cancer Society Updates Colorectal Cancer Screening Guideline (free)
Commentaries: American Cancer Society recommends earlier colorectal cancer screening – Reuters (free) AND American Cancer Society advises colorectal screens at 45, not 50 – UPI (free) AND Cancer Group Calls for Colorectal Cancer Screening Starting at Age 45 – The New York Times (10 articles per month are free) AND Get Screened Earlier For Colorectal Cancer, Urges American Cancer Society – NPR (free)
Related Guidelines (all suggest screening should begin at age 50 years in average-risk individuals): Colorectal Cancer Screening – U.S. Preventive Services Task Force (free resources) AND Recommendations on screening for colorectal cancer in primary care – Canadian Task Force on Preventive Health Care (free) AND Colorectal Cancer Screening: Recommendations for Physicians and Patients from the U.S. Multi-Society Task Force on Colorectal Cancer – The American Journal of Gastroenterology (free)
Guidelines and Current Issues in Cancer Screening
1 Jun, 2018 | 03:23h | UTCSee Also Cancer Screening Guidelines from Other Organizations: U.S. Preventive Services Task Force Recommendations (all free) AND Canadian Task Force on Preventive Health Care Published Guidelines (all free)
ESMO Guideline: Soft Tissue and Visceral Sarcomas
1 Jun, 2018 | 03:06h | UTC
ESMO Guideline: Hodgkin lymphoma
1 Jun, 2018 | 03:12h | UTC
ESMO Guideline: Gastrointestinal Stromal Tumors
1 Jun, 2018 | 03:13h | UTC
ASCO Guideline: Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer
1 Jun, 2018 | 02:59h | UTCCommentary: Updated Guideline for HER2 Testing in Breast Cancer Aids Physicians, Patients and their Families – College of American Pathologists, via NewsWise (free)
Perspective: Real-World Evidence and Randomized Studies in the Precision Oncology Era
1 Jun, 2018 | 03:02h | UTC
Meta-Analysis: Pharmacological Therapies for the Treatment of Opioid-induced Constipation
29 May, 2018 | 17:50h | UTCEfficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and network meta-analysis – Gut (link to abstract – $ for full-text)
Commentary: Naloxone, naldemedine appear best for opioid-induced constipation after laxatives – ACP Gastroenterology (free)