Oncology – Gastrointestinal
A comprehensive and comparative review of global gastric cancer treatment guidelines.
26 Apr, 2022 | 07:39h | UTC
RCT: Pembrolizumab vs. chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer.
24 Apr, 2022 | 23:52h | UTCPembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-label, phase 3 study – The Lancet Oncology (link to abstract – $ for full-text)
M-A: Clinical efficacy of adjuvant treatments for patients with resected biliary tract cancer.
22 Apr, 2022 | 09:26h | UTC
AI reduces miss rate of precancerous polyps in colorectal cancer screening.
19 Apr, 2022 | 01:32h | UTCNews Release: AI reduces miss rate of precancerous polyps in colorectal cancer screening – Mayo Clinic
Original Study: Impact of Artificial Intelligence on Miss Rate of Colorectal Neoplasia – Gastroenterology (link to abstract – $ for full-text)
Review | Frontline therapy for advanced hepatocellular carcinoma.
19 Apr, 2022 | 01:23h | UTC
M-A of randomized controlled trials: Intrathoracic vs. cervical anastomosis in esophagectomy for esophageal cancer.
12 Apr, 2022 | 08:47h | UTC
Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.
8 Apr, 2022 | 10:58h | UTCInvited Commentary: Global epidemiology and prevention of colorectal cancer – The Lancet Gastroenterology & Hepatology (free registration required)
RCT: Laparoscopic sentinel node navigation surgery for stomach preservation in patients with early gastric cancer.
8 Apr, 2022 | 09:59h | UTC
Commentary on Twitter
In a phase III noninferiority trial of laparoscopic sentinel node navigation surgery vs standard gastrectomy for gastric cancer, 3-year DFS was 91.8% vs 95.5%, but with fewer complications, better physical function, improved nutrition & similar DSS/OS: https://t.co/A7Z8tejiIA
— NatureRevClinOncol (@NatRevClinOncol) March 30, 2022
Case-cohort study: The relative and attributable risks of cardia and non-cardia gastric cancer associated with Helicobacter pylori infection in China.
7 Apr, 2022 | 08:22h | UTCCommentary: Helicobacter pylori infection and risk of gastric cancer – The Lancet Public Health
Cohort Study: Recipient and donor outcomes after living-donor liver transplant for unresectable colorectal liver metastases.
6 Apr, 2022 | 10:23h | UTCCommentaries:
Living-Donor Liver Transplant Promising for CRC With Liver Mets – HealthDay
Commentary on Twitter
Study suggests living-donor liver transplant is a promising option for meticulously selected patients with unresectable colorectal cancer liver metastases. https://t.co/p6Jbzb73DL
— JAMA Surgery (@JAMASurgery) March 30, 2022
Review: Translational advances in pancreatic ductal adenocarcinoma therapy.
6 Apr, 2022 | 10:05h | UTCTranslational advances in pancreatic ductal adenocarcinoma therapy – Nature Cancer (if the link is paywalled, try this one)
Commentary on Twitter
🔥Don't miss this beautiful review @NatureCancer on translational advances in pancreatic ductal adenocarcinoma by #AbdelNasserHosein, #StephanieKDougan, #AndrewJAguirre & @Aiims1742
Read it here🔥👇https://t.co/t6CWD0KCoxhttps://t.co/6RjCQ5NqNo
— Nature Cancer (@NatureCancer) March 29, 2022
ACG Guideline: Diagnosis and management of Barrett’s esophagus.
4 Apr, 2022 | 01:07h | UTC
Long-term follow-up of RCT: Nivolumab plus chemotherapy or ipilimumab in gastro-esophageal cancer.
1 Apr, 2022 | 08:37h | UTCNivolumab plus chemotherapy or ipilimumab in gastro-oesophageal cancer – Nature
Commentary on Twitter
New data from CheckMate 649 confirm that the OS benefit of nivolumab added to chemotherapy for advanced-stage gastroesophageal adenocarcinoma persists beyond 24 mo (HR 0.79; 95% CI 0.71-0.88); however, nivo+ipi did not improve OS vs chemotherapy alone: https://t.co/2Pom4zD7oX
— NatureRevClinOncol (@NatRevClinOncol) March 25, 2022
SEOM-GEMCAD-TTD Clinical Guideline for the diagnosis and treatment of esophageal cancer.
31 Mar, 2022 | 07:48h | UTC
Cohort Study: Risk factors for complications after surgery for pancreatic neuroendocrine tumors.
30 Mar, 2022 | 10:03h | UTCRisk factors for complications after surgery for pancreatic neuroendocrine tumors – Surgery
Commentary on Twitter
Risk factors for complications after surgery for pancreatic neuroendocrine tumors@hpb_so @NANETS1 @AHPBA @EAHPBA @Cancer_UMCU @UMCU_Intl @me4_so
🆓#openaccess #VisualAbstract
https://t.co/uVNFRqpKKP pic.twitter.com/iIVbQSBawD— SURGERY Journal (@SurgJournal) March 25, 2022
Cohort Study: Characteristics and prognosis of acquired resistance to immune checkpoint inhibitors in gastrointestinal cancer.
30 Mar, 2022 | 08:47h | UTCInvited Commentary: Acquired Immunotherapy Resistance in Gastrointestinal Cancers – JAMA Network Open
Review: Surgical management of gastric cancer.
25 Mar, 2022 | 08:48h | UTCSurgical Management of Gastric Cancer: A Review – JAMA Surgery (free for a limited period)
Review | Imaging findings of gastrointestinal tract tumors in children and adolescents.
25 Mar, 2022 | 08:38h | UTC
SEOM-GEMCAD-TTD clinical guidelines for localized rectal cancer.
25 Mar, 2022 | 08:21h | UTC
Multidisciplinary evidence-based recommendations for the management of malignant bowel obstruction in advanced cancer.
24 Mar, 2022 | 08:45h | UTC
M-A: Risk of peritoneal carcinomatosis after risk-reducing salpingo-oophorectomy in BRCA1/2 pathogenic variant (PV) carriers.
22 Mar, 2022 | 07:58h | UTC
Risk of colorectal cancer is associated with lifetime excess weight.
18 Mar, 2022 | 08:07h | UTCRisk of Colorectal Cancer Associated With Lifetime Excess Weight – JAMA Oncology
Diagnostic approach to incidentally detected pancreatic cystic lesions.
18 Mar, 2022 | 08:11h | UTCRelated:
Cystic pancreatic lesions: MR imaging findings and management.
Recommendations for the management of incidental pancreatic findings in adults.
Pancreatic cystic neoplasms: a review of current recommendations for surveillance and management
Management of Pancreatic Cystic Lesions
Consensus Recommendations: Diagnosis and Surveillance of Incidental Pancreatic Cystic Lesions
Review: Pancreatic Cystic Lesions
Guidelines on pancreatic cystic neoplasms
RCT: Short-term radiotherapy plus chemotherapy vs. long-term chemoradiotherapy in locally advanced rectal cancer.
18 Mar, 2022 | 07:39h | UTC
RCT: Toripalimab plus chemotherapy in treatment-naïve, advanced esophageal squamous cell carcinoma.
17 Mar, 2022 | 08:07h | UTC
Commentary on Twitter
Phase III JUPITER-03 trial testing addition of the anti-PD-1 mAb toripalimab to first-line chemotherapy for advanced-stage ESCC, mPFS was 5.7 vs 5.5 months, although 1-year PFS was 27.8% vs 6.1% (HR 0.58) and mOS was 17 vs 11 months (HR 0.58): https://t.co/jNSVzNiAzR #esocsm
— NatureRevClinOncol (@NatRevClinOncol) March 10, 2022