Nephrology
Guideline: Screening and Management of High Blood Pressure in Children and Adolescents
22 Aug, 2017 | 13:08h | UTCNews release: AAP issues new pediatric hypertension clinical practice guideline – AAP News (free)
Meta-analysis: Acute Kidney Injury After Computed Tomography
21 Aug, 2017 | 01:41h | UTCAcute Kidney Injury After Computed Tomography: A Meta-analysis – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary: When kidneys are injured, CT contrast isn’t the culprit – Health Imaging (free)
Related article: Risk of Acute Kidney Injury After Intravenous Contrast Media Administration – Annals of Emergency Medicine (free)
Source: Hospital Medicine Virtual Journal Club
Compared with noncontrast CT, contrast-enhanced CT was not significantly associated with either acute kidney injury, need for renal replacement therapy, or all-cause mortality.
Standard of Care in Critically Ill Adult Patients With Atypical Hemolytic Uremic Syndrome
17 Aug, 2017 | 18:22h | UTCSource: Critical Care Reviews Newsletter
Comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients
17 Aug, 2017 | 17:55h | UTCSource: Critical Care Reviews Newsletter
Early initiation of RRT in critically ill patients did not result in reduced mortality, change in renal function recovery, dependence, duration of RRT, renal recovery time, mechanical ventilation time or complications.
Blood pressure targets for hypertension in older adults
15 Aug, 2017 | 19:55h | UTCBlood pressure targets for hypertension in older adults – Cochrane Library (free)
Full review: Blood pressure targets for hypertension in older adults – Cochrane Library (link to abstract – $ for full-text)
Related guideline: Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older to Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline From ACP and AAFP (free)
“At the present time there is insufficient evidence to know whether a higher BP target (less than150 to 160/95 to 105 mmHg) or a lower BP target (less than 140/90 mmHg) is better for older adults with high BP”
Ibuprofen versus placebo effect on acute kidney injury in ultramarathons
15 Aug, 2017 | 16:09h | UTCIbuprofen versus placebo effect on acute kidney injury in ultramarathons: a randomised controlled trial – Emergency Medicine Journal (link to abstract – $ for full-text)
Commentaries: Ibuprofen linked to slight risk of kidney damage in ultramarathoners – Reuters (free) AND Study reveals harmful effects on kidney of Ibuprofen – Stanford Daily (free)
Acute Kidney Injury in Pregnancy-specific Disorders
15 Aug, 2017 | 15:39h | UTCReview: Acute Kidney Injury in Pregnancy-specific Disorders – Indian Journal of Nephrology (free)
Dual Kidney Transplantation: A Review of Past and Prospect for Future
15 Aug, 2017 | 15:36h | UTCReview: Dual Kidney Transplantation: A Review of Past and Prospect for Future – International Scholarly Research Notices (free)
Day-to-Day Blood Pressure Variability and Risk of Dementia
14 Aug, 2017 | 16:12h | UTCCommentaries: Fluctuations in home-monitored blood pressure may raise dementia risk – Circulation Journal Report (free) AND Fluctuations in Blood Pressure Linked to Vascular Dementia – MedPage Today (free registration required) AND Fluctuating Home Blood Pressure Linked to Dementia – Medscape (free registration required) AND Blood pressure fluctuations linked to dementia – Reuters (free)
Review: Palliative and end-of-life care in nephrology
11 Aug, 2017 | 17:08h | UTCNarrative review: Palliative and end-of-life care in nephrology: moving from observations to interventions – Current Opinion in Nephrology & Hypertension, via Medscape (free registration required)
Lithium Associated With a Higher Risk of Chronic Kidney Disease in Older Adults
11 Aug, 2017 | 15:53h | UTCLithium Use, but Not Valproate Use, Is Associated With a Higher Risk of Chronic Kidney Disease in Older Adults With Mental Illness – The Journal of Clinical Psychiatry (link to abstract -$ for full-text)
Case-control study suggests Lithium is associated with increased risk of chronic kidney disease.
Epidemiology, pathophysiology, and management of uric acid urolithiasis
11 Aug, 2017 | 12:41h | UTCReview: Epidemiology, pathophysiology, and management of uric acid urolithiasis: A narrative review – Journal of Advanced Research (free)
Nephrolithiasis more common in patients with gout
10 Aug, 2017 | 22:32h | UTCCommentaries: Gout Patients Run Higher Risk of Kidney Stones – MedPage Today (free registration required) AND Gout associated with elevated risk for kidney stones – MedWire News (free)
“60% increased risk of first-time nephrolithiasis versus general population, with little protection from allopurinol” (from MedPage Today)
Challenges in Treating Cardiovascular Disease: Restricting Sodium and Managing Hyperkalemia
10 Aug, 2017 | 21:45h | UTCReview: Challenges in Treating Cardiovascular Disease: Restricting Sodium and Managing Hyperkalemia – Mayo Clinic Proceedings (free)
Dietary Approaches in the Management of Diabetic Patients with Kidney Disease
9 Aug, 2017 | 15:51h | UTCReview: Dietary Approaches in the Management of Diabetic Patients with Kidney Disease – Nutrients (free)
Effect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy:
3 Aug, 2017 | 19:57h | UTCEffect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Steroid treatment for type of kidney disease associated with increased risk for serious infections – The JAMA Network (free)
Renal outcomes seemed to be less frequent in the group using methylprednisolone (5,9% vs 15,9%), but the trial was stopped early due to a significantly increased risk of serious adverse events with oral methylprednisolone vs placebo (14.7% vs 3.2%, primarily excess infections)
Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors
3 Aug, 2017 | 13:33h | UTC
KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors
3 Aug, 2017 | 13:31h | UTC
Kidney dysfunction in patients with pulmonary arterial hypertension
3 Aug, 2017 | 13:25h | UTCReview: Kidney dysfunction in patients with pulmonary arterial hypertension – Pulmonary Circulation (free)
Chronic kidney disease in adults – NICE Quality Standard
28 Jul, 2017 | 16:05h | UTCChronic kidney disease in adults – NICE Quality Standard (free)
Commentary: Give chronic kidney disease patients a statin, doctors urged – OnMedica (free)
Updates in Management of Hyperkalemia
25 Jul, 2017 | 00:43h | UTCPractical Review: Updates in Management of Hyperkalemia – emDocs Cases (free)
Biomarkers in renal transplantation: An updated review
23 Jul, 2017 | 23:38h | UTCReview: Biomarkers in renal transplantation: An updated review – World Journal of Transplantation (free)
Chronic kidney disease and the global NCDs agenda
23 Jul, 2017 | 15:56h | UTCChronic kidney disease and the global NCDs agenda – BMJ Global Health (free)
Related: Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy – The Lancet (free registration required) AND Worldwide access to treatment for end-stage kidney disease: a systematic review – The Lancet (free registration required) AND One in 10 People Worldwide Have Chronic Kidney Disease – Medscape (free registration required)
Treatment of diabetic kidney disease: current and future targets
21 Jul, 2017 | 18:14h | UTCReview: Treatment of diabetic kidney disease: current and future targets – Korean Journal of Internal Medicine (free)
Rhabdomyolysis & Exertional Heat Stroke
20 Jul, 2017 | 00:03h | UTCAs Workouts Intensify, a Harmful Side Effect Grows More Common – New York Times (10 articles per month are free)
Related practical review: Exercise-Induced Emergencies in the Heat: Rhabdomyolysis & Exertional Heat Stroke – emDocs (free)