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Nephrology

Research: Effect of Sertraline on Depressive Symptoms in Patients With Chronic Kidney Disease

6 Nov, 2017 | 14:43h | UTC

Effect of Sertraline on Depressive Symptoms in Patients With Chronic Kidney Disease Without Dialysis Dependence: The CAST Randomized Clinical Trial – JAMA (free)

Editorial: Treating Depression in Patients With Advanced CKD: Beyond the Generalizability Frontier (free)

Commentary: Standard Antidepressant May Not Help Patients with Chronic Kidney Disease – UT Southwestern Medical Center, via NewsWise (free)

“Not only doesn’t help treat moderate depression, sertraline causes worse nausea (NNH=8) & diarrhea (NNH=10)” (RT @AnilMakam see Tweet 1 and Tweet 2)

 


Research: Balanced Crystalloids vs Saline for Critically Ill Adults

5 Nov, 2017 | 20:38h | UTC

Balanced Crystalloids vs Saline for Critically Ill Adults – American College of Chest Physicians Annual Meeting (free abstract)

Related Study: Balanced Crystalloids vs Saline for Noncritically Ill Adults in the Emergency Department – American College of Chest Physicians Annual Meeting (free abstract)

Commentaries: Landmark Trials Deliver Evidence to Rethink Saline Use – Medscape (free registration required) AND Saline on the Ropes? Studies find balanced crystalloid fluids safer – MedPage Today (free registration required)

 


Research: Enjoyment of Spicy Flavor Enhances Central Salty

5 Nov, 2017 | 19:46h | UTC

Enjoyment of Spicy Flavor Enhances Central Salty-Taste Perception and Reduces Salt Intake and Blood Pressure – Hypertension (free)

Commentary: Can spicy foods curb salt cravings or lower blood pressure? – Reuters (free) AND Need to cut down on salt? Try something spicy instead – Medical News Today (free)

 


Guideline on the Evaluation and Care of Living Kidney Donors

5 Nov, 2017 | 19:21h | UTC

KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors – Transplantation (free)

See also: Summary of KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors (free)

News release: KDIGO Guidelines on Living Kidney Donors: A Call for A Paradigm Shift (free)

 


Systematic Review: Blood pressure targets in people with cardiovascular disease

17 Oct, 2017 | 18:59h | UTC

Blood pressure targets in people with cardiovascular disease – Cochrane Library (free)

 


Review: Calcium and Cardiovascular Disease

17 Oct, 2017 | 18:00h | UTC

Calcium and Cardiovascular Disease – Endocrinology and Metabolism (free)

 


Review: The Sick ESRD Patient

12 Oct, 2017 | 18:23h | UTC

The Sick ESRD Patient – emDocs Cases (free)

 


Review: Renal Function Considerations for Stroke Prevention in Atrial Fibrillation

12 Oct, 2017 | 17:59h | UTC

Renal Function Considerations for Stroke Prevention in Atrial Fibrillation – The American Journal of Medicine (free)

 


Review: Hepatitis B in renal transplant patients

12 Oct, 2017 | 17:53h | UTC

Hepatitis B in renal transplant patients – World Journal of Hepatology (free)

 


Review: acute kidney injury in critically ill patient

12 Oct, 2017 | 17:49h | UTC

Practical approach to detection and management of acute kidney injury in critically ill patient – Journal of Intensive Care (free)

 


Research: Impact of the Commercialization of Three Generic Angiotensin II Receptor Blockers on Adverse Events in Quebec, Canada

10 Oct, 2017 | 01:05h | UTC

Impact of the Commercialization of Three Generic Angiotensin II Receptor Blockers on Adverse Events in Quebec, Canada: A Population-Based Time Series Analysis – Circulation: Cardiovascular Quality and Outcomes (free)

Commentaries: Generic Blood Pressure Drugs May Be Tied to Increase in Adverse Events – Physician’s First Watch (free) AND Generic ARBs Linked to Increased Adverse Events – TCTMD (free)

As in any observational study, association does not necessarily imply causation.

 


Research: Serum Calcium and Risk of Sudden Cardiac Arrest in the General Population

10 Oct, 2017 | 01:02h | UTC

Serum Calcium and Risk of Sudden Cardiac Arrest in the General Population – Mayo Clinic Proceedings (link to abstract – $ for full-text)

Commentaries: Low serum calcium may increase risk of sudden cardiac arrest – EurekAlert (free) AND Low calcium may raise cardiac arrest risk by twofold – Medical News Today (free)

 


Systematic Review: Self-monitoring of blood pressure in hypertension

1 Oct, 2017 | 16:14h | UTC

Self-monitoring of blood pressure in hypertension: A systematic review and individual patient data meta-analysis – PLOS Medicine (free)

Commentary: Home blood pressure monitoring works best with extra support – Reuters (free)

 


Research: Effect of a Community Health Worker–Led Multicomponent Intervention on Blood Pressure Control

1 Oct, 2017 | 16:13h | UTC

Effect of a Community Health Worker–Led Multicomponent Intervention on Blood Pressure Control in Low-Income Patients in Argentina: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentary: Community Intervention among Low-Income Patients Results in Improved Blood Pressure Control – The JAMA Network (free)

“The proportion of patients with controlled hypertension (BP <140/90 mm Hg) increased from 17 percent at baseline to 73 percent in the intervention group and from 18 percent to 52 percent in the usual care group”.

 


Review: Lipid lowering in renal disease

1 Oct, 2017 | 15:06h | UTC

Lipid lowering in renal disease – Australian Prescriber (free)

Source: Cardiology Research Review Australia

 


Review: Using Best Evidence for the Management of Hypertension

27 Sep, 2017 | 14:46h | UTC

Using Best Evidence for the Management of Hypertension – Therapeutics Initiative (free)

 


All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease

24 Sep, 2017 | 21:26h | UTC

All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease – Hypertension (link to abstract – free PDF via @unpaywall)

Commentaries: Hypertensive disorders of pregnancy increase future risk of heart disease – Cardiovascular Business (free) AND A type of hypertension during pregnancy more dangerous than thought – AHA News (free)

See related articles and commentaries in our August 22nd issue (see #3)

 


Effects of Intensive Systolic Blood Pressure Control on Kidney and Cardiovascular Outcomes in Persons Without Kidney Disease

20 Sep, 2017 | 21:12h | UTC

Effects of Intensive Systolic Blood Pressure Control on Kidney and Cardiovascular Outcomes in Persons Without Kidney Disease: A Secondary Analysis of a Randomized Trial – Annals of Internal Medicine (free)

Commentary: Cardiovascular benefits of intensive systolic blood pressure control may outweigh risks of chronic kidney disease events – 2 Minute Medicine (free)

Blood pressure measures in the SPRINT trial were done in a different way than most trials. If these results are to be incorporated in clinical practice, blood pressure measurement must be done in the same way. More details in Cardiobrief: Can SPRINT Be Used To Inform Hypertension Treatment? (free)

 


FDA recommends separating dosing of potassium-lowering drug sodium polystyrene sulfonate (Kayexalate) from all other oral drugs

20 Sep, 2017 | 20:50h | UTC

FDA Drug Safety Communication: FDA recommends separating dosing of potassium-lowering drug sodium polystyrene sulfonate (Kayexalate) from all other oral drugs (free)

Commentary: Don’t Give Kayexalate With Other Oral Drugs, FDA Warns – Medscape (free registration required)

“Patients should take orally administered prescription and over-the-counter (OTC) medicines at least 3 hours before or 3 hours after sodium polystyrene sulfonate”

 


Renal denervation: What happened, and why?

18 Sep, 2017 | 13:52h | UTC

Renal denervation: What happened, and why? – Cleveland Clinic Journal of Medicine (free)

 


Review: Pre-existing arterial pathologic changes affecting arteriovenous fistula patency and cardiovascular mortality in hemodialysis patients

16 Sep, 2017 | 18:03h | UTC

Pre-existing arterial pathologic changes affecting arteriovenous fistula patency and cardiovascular mortality in hemodialysis patients – Korean Journal of Internal Medicine (free)

 


Meta-analysis: More Intensive vs Less Intensive Blood Pressure Lowering in Chronic Kidney Disease

15 Sep, 2017 | 19:16h | UTC

Association Between More Intensive vs Less Intensive Blood Pressure Lowering and Risk of Mortality in Chronic Kidney Disease Stages 3 to 5: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Intensive blood pressure lowering linked to decreased mortality in patients with chronic kidney disease – 2 Minute Medicine (free) AND Intensive BP Lowering in Chronic Kidney Disease Associated with Lower Mortality – Physician’s First Watch (free) AND Is Strict BP Control a Good Bet for CKD Patients? – MedPage Today (free registration required)

 


Guideline: Severe Hypertension During Pregnancy and the Postpartum Period

12 Sep, 2017 | 21:06h | UTC

Guideline: National Partnership for Maternal Safety: Consensus Bundle on Severe Hypertension During Pregnancy and the Postpartum Period – Obstetrics & Gynecology (free)

Commentary: Management of Severe Maternal Hypertension During Pregnancy and Postpartum – Journal Watch (free)

 


Review: The Nephrotoxicity of Vancomycin

12 Sep, 2017 | 20:53h | UTC

The Nephrotoxicity of Vancomycin – Clinical Pharmacology & Therapeutics (free)

 


Review: Uremic pericarditis, pericardial effusion, and constrictive pericarditis in end-stage renal disease

12 Sep, 2017 | 20:51h | UTC

Uremic pericarditis, pericardial effusion, and constrictive pericarditis in end-stage renal disease: Insights and pathophysiology – Clinical Cardiology (free)

 


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