Nephrology
Research: Healthy diet may not offset high salt intake
8 Mar, 2018 | 21:33h | UTCRelation of Dietary Sodium (Salt) to Blood Pressure and Its Possible Modulation by Other Dietary Factors: The INTERMAP Study – Hypertension (link to abstract – $ for full-text)
Commentaries: Healthy diet may not offset high salt intake – Imperial College London (free) AND Dietary sodium’s impact may not be offset by other aspects of a diet – AHA / ASA Newsroom (free)
Research: Comparative cardiovascular safety of non-steroidal anti-inflammatory drugs in patients with hypertension
8 Mar, 2018 | 20:44h | UTCComparative cardiovascular safety of non-steroidal anti-inflammatory drugs in patients with hypertension: a population-based cohort study – British Journal of Clinical Pharmacology (link to abstract – $ for full-text)
Commentary: Cardiovascular Risk Compared Among COX-2 Selective, Nonselective NSAIDs – MPR (free)
Points of Concern in Post Acute Kidney Injury Management
8 Mar, 2018 | 20:21h | UTCPoints of Concern in Post Acute Kidney Injury Management – Nephron (free)
Source: Critical Care Reviews Newsletter
Reviews: Post-Contrast Acute Kidney Injury
8 Mar, 2018 | 20:18h | UTCSource: Critical Care Reviews Newsletter
Balanced Crystalloids vs Saline in Hospitalized Patients
2 Mar, 2018 | 02:10h | UTCBalanced Crystalloids versus Saline in Critically Ill Adults – New England Journal of Medicine (free)
Related article: Balanced Crystalloids versus Saline in Noncritically Ill Adults – New England Journal of Medicine (free)
Commentary: Balanced Crystalloids May Be Better Than Saline for Critically Ill Patients – NEJM Physician’s First Watch (free)
“Balanced crystalloids may be superior to saline in critically ill patients — but not in patients hospitalized outside an ICU” (from Physician’s First Watch)
Research: Efficacy of self-monitored blood pressure for titration of antihypertensive medication
2 Mar, 2018 | 01:53h | UTCCommentaries: Hypertension: time for doctors to switch the driver’s seat? (free) AND Should home-based blood pressure monitoring be commonplace in NHS? – University of Oxford News & Events (free)
“Self-monitoring, with or without telemonitoring, when used by general practitioners to titrate antihypertensive medication in individuals with poorly controlled blood pressure, leads to significantly lower blood pressure than titration guided by clinic readings”.
Research: Spironolactone Vs Clonidine for Resistant Hypertension
2 Mar, 2018 | 00:54h | UTCCommentary: Spironolactone bests clonidine as fourth drug for resistant hypertension – Univadis (free registration required)
Systematic Review: Interventions to prevent hemodynamic instability during renal replacement therapy in critically ill patients
27 Feb, 2018 | 17:24h | UTC
Research: Readmissions Following a Hospitalization for Cardiovascular Events in Dialysis Patients
27 Feb, 2018 | 15:52h | UTCReadmissions Following a Hospitalization for Cardiovascular Events in Dialysis Patients: A Retrospective Cohort Study – Journal of the American Heart Association (free for a limited period)
“Roughly 1 in 3 CVD hospitalizations resulted in 30‐day readmission; nearly 1 in 20 was followed by death within 30 days”.
Meta-Analysis: Neurocognitive and Educational Outcomes in Children and Adolescents with CKD
27 Feb, 2018 | 15:47h | UTCCommentaries: Analysis finds lower IQ in children with chronic kidney disease – American Society of Nephrology, via ScienceDaily (free) AND CKD Linked to Cognitive Impairment in Kids – MedPage Today (free registration required)
Update on Diabetic Nephropathy
23 Feb, 2018 | 01:02h | UTCUpdate on Diabetic Nephropathy: Core Curriculum 2018 – American Journal of Kidney Diseases (free)
Guideline Synopsis: Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder
23 Feb, 2018 | 01:05h | UTC
Research: Ischaemic stroke, haemorrhage, and mortality in older patients with chronic kidney disease newly started on anticoagulation for atrial fibrillation
22 Feb, 2018 | 23:35h | UTCCommentaries: Anticoagulants Tied With Stroke, Hemorrhage in CKD – Renal & Urology News (free) AND Could a Blood Thinner Actually Raise Stroke Risk for Some? – HealthDay (free) AND Anticoagulants for Patients with Afib and Kidney Disease? Study Yields Mixed Findings – Physician’s First Watch (free) AND Blood-thinning drugs designed to cut stroke risk may actually increase it – The Guardian (free)
“Given the lack of guidelines, the decision to start anticoagulant treatment in patients with chronic kidney disease and new onset atrial fibrillation should be made on an individual basis, concludes research” (via @bmj_latest see Tweet)
Avoid common mistakes when treating hyponatremia
22 Feb, 2018 | 23:30h | UTCAvoid common mistakes when treating hyponatremia – ACP Hospitalist (free)
Meta-Analysis: Effects of uric acid-lowering therapy in patients with chronic kidney disease
22 Feb, 2018 | 23:05h | UTCCommentary: Gout medication may slow progression of chronic kidney disease – NIHR Signal (free)
Research: Potential Yield of Imminent Death Kidney Donation
22 Feb, 2018 | 22:47h | UTCPotential Yield of Imminent Death Kidney Donation – American Journal of Transplantation, via Medscape (free registration required)
Review: Thrombotic Microangiopathy and the Kidney
22 Feb, 2018 | 21:46h | UTCThrombotic Microangiopathy and the Kidney – Clinical Journal of the American Society of Nephrology (free)
Source: Critical Care Reviews Newsletter
Research: Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine
16 Feb, 2018 | 02:32h | UTCOutcomes after Angiography with Sodium Bicarbonate and Acetylcysteine – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: No benefit of sodium bicarbonate or acetylcysteine for prevention of complications after angiography: The PRESERVE trial – 2 Minute Medicine (free) AND Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine – NEJM Resident 360 (free)
“Among patients at high risk for renal complications who were undergoing angiography, there was no benefit of intravenous sodium bicarbonate over intravenous sodium chloride or of oral acetylcysteine over placebo for the prevention of death, need for dialysis, or persistent decline in kidney function at 90 days or for the prevention of contrast-associated acute kidney injury”.
Research: Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients
16 Feb, 2018 | 01:26h | UTC“Trimethoprim is associated with a greater risk of acute kidney injury and hyperkalaemia compared with other antibiotics used to treat UTIs, but not a greater risk of death”
Research: Hypertension Common After Severe Preeclampsia
15 Feb, 2018 | 10:49h | UTCBlood Pressure Profile 1 Year After Severe Preeclampsia – Hypertension (link to abstract – $ for full-text)
Commentaries: High blood pressure in pregnancy may not disappear afterward – Reuters (free) AND Ambulatory Monitoring Shows Persistent HTN Common After Severe Preeclampsia – MedPage Today (free registration required)
Research: Blood Pressure Variability and Risk of Cardiovascular Events and Death
15 Feb, 2018 | 10:38h | UTCBlood pressure variability and risk of cardiovascular events and death in patients with hypertension and different baseline risks – European Heart Journal (link to abstract – $ for full-text)
Commentary: Blood Pressure Variability and Risk of CV Events – American College of Cardiology, Latest in Cardiology (free)
Review: New Developments in Hepatorenal Syndrome
9 Feb, 2018 | 11:40h | UTCNew Developments in Hepatorenal Syndrome – Clinical Gastroenterology and Hepatology (free)
Research: Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease
4 Feb, 2018 | 18:36h | UTCMetformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or 4 – Diabetes Care (link to abstract – $ for full-text)
Commentaries: How I learned to stop worrying and love metformin – NephJC (free) AND Adjusted-Dose Metformin Appears Safe in Patients With Type 2 Diabetes and Chronic Kidney Disease Stage 3 or 4 – PracticeUpdate (free registration required)
Research: History of Childhood Kidney Disease and Risk of Adult End-Stage Renal Disease
4 Feb, 2018 | 18:34h | UTCHistory of Childhood Kidney Disease and Risk of Adult End-Stage Renal Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: Childhood Kidney Disease and Adult ESRD (free)
Commentaries: History of Childhood Kidney Disease Linked to Risk of ESRD – Physician’s Weekly (free) AND Childhood Kidney Disease Predicts Adult ESRD – MedPage Today (free registration required)
Meta-Analysis: Mid- and Long-Term Health Risks in Living Kidney Donors
4 Feb, 2018 | 18:29h | UTCMid- and Long-Term Health Risks in Living Kidney Donors: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Analysis looks at long-term risks of living kidney donation – American College of Physicians, via EurekAlert (free) AND What Are The Health Risks To Living Kidney Donors? – MedicalResearch.com (free) AND Living kidney donors have low but elevated risk of renal failure – Reuters (free)