Nephrology
Podcast: Kidney Transplant for the Internist
28 Apr, 2020 | 04:16h | UTC#210 Kidney Transplant for the Internist – The Curbsiders Internal Medicine Podcast
See also: Episode List
[Abstract Only] Meta-Analysis: Delayed vs. Early Initiation of Renal Replacement Therapy for Severe Acute Kidney Injury
26 Apr, 2020 | 21:15h | UTC
Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths
23 Apr, 2020 | 09:27h | UTCCommentaries: Salt substitution could prevent almost half a million deaths from CVD in China – George Institute for Global Health AND Embracing salt substitutes could help China prevent 450K CVD deaths per year – Cardiovascular Business
New EULAR Recommendations for the Management of Lupus Nephritis
8 Apr, 2020 | 01:16h | UTCCommentary: EULAR, ERA–EDTA issue guidelines for managing lupus nephritis – Medicine Matters
Related Guidelines: Consensus of the Brazilian Society of Rheumatology for the diagnosis, management and treatment of lupus nephritis (free) AND 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus (free) AND 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus (free) AND Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology (free) AND The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus (free) AND Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus (free PDF)
Related Reviews: Update on Lupus Nephritis – Clinical Journal of the American Society of Nephrology (free) AND Immunosuppressive Treatment for Proliferative Lupus Nephritis – Cochrane Library (free) AND Induction and Maintenance Immunosuppression Treatment of Proliferative Lupus Nephritis: A Network Meta-analysis of Randomized Trials. – American Journal of Kidney Diseases (free)
Study: Saline vs. Lactated Ringer’s Solution in Surgical Patients
7 Apr, 2020 | 04:11h | UTC
COVID-19 and Renin-Angiotensin System Blockers
30 Mar, 2020 | 02:00h | UTCRenin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers – Hypertension AND Commentary: COVID-19 alert: Heart and kidney patients should keep taking their medicines – University of Miami Miller School of Medicine
Related Guidelines: HFSA/ACC/AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19 – American College of Cardiology AND The Renal Association, UK position statement on COVID-19 and ACE Inhibitor/Angiotensin Receptor Blocker use AND Position Statement of the ESC Council on Hypertension on ACE-Inhibitors and Angiotensin Receptor Blockers – European Society of Cardiology
NICE COVID-19 Rapid Guideline: Dialysis Service Delivery
23 Mar, 2020 | 01:30h | UTCSee also: COVID-19: Updates for Nephrologists (free resources)
COVID-19: Updates for Nephrologists
25 May, 2020 | 00:02h | UTCPodcast:
- NEW – Podcast 267: Acute kidney injury in COVID-19 — how one New York system dealt with it – NEJM Clinical Conversations (05/2020)
Guidelines:
- COVID-19 rapid guideline: chronic kidney disease – National Institute for Health and Care Excellence (05/2020)
- COVID-19 rapid guideline: acute kidney injury in hospital – National Institute for Health and Care Excellence (05/2020)
- COVID-19 rapid guideline: dialysis service delivery – National Institute for Health and Care Excellence (03/2020)
- Guidance for Infection Control and Prevention of Coronavirus Disease 2019 (COVID-19) in dialysis facilities – Centers for Medicare & Medicaid Services (03/2020)
- Interim Additional Guidance for Infection Prevention and Control Recommendations for Patients with Suspected or Confirmed COVID-19 in Outpatient Hemodialysis Facilities – Centers for Disease Control and Prevention (03/2020)
- Recommendations for the prevention, mitigation and containment of the emerging SARS-CoV-2 (COVID-19) pandemic in haemodialysis centres – Nephrology Dialysis Transplantation
- HFSA/ACC/AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19 – American College of Cardiology AND Commentaries: Patients with COVID-19 should keep taking key CVD medications – Cardiovascular Business AND Patients taking ACE-i and ARBs who contract COVID-19 should continue treatment, unless otherwise advised by their physician – American Heart Association (03/2020)
- The Renal Association, UK position statement on COVID-19 and ACE Inhibitor/Angiotensin Receptor Blocker use (03/2020)
- Position Statement of the ESC Council on Hypertension on ACE-Inhibitors and Angiotensin Receptor Blockers – European Society of Cardiology (03/2020)
Articles:
- Multiorgan and Renal Tropism of SARS-CoV-2 – New England Journal of Medicine (05/2020)
- Clinical Characteristics of and Medical Interventions for COVID-19 in Hemodialysis Patients in Wuhan, China – Journal of the American Society of Nephrology (05/2020)
- Renal Involvement and Early Prognosis in Patients with COVID-19 Pneumonia – Journal of the American Society of Nephrology (05/2020)
- Recommendations for prevention and management of COVID-19 in peritoneal dialysis patients – Chronic Diseases and Translational Medicine (05/2020)
- [Preprint] Acute Kidney Injury in Hospitalized Patients with COVID-19 – medRxiv (05/2020)
- [Preprint] AKI during COVID-19 infection: low incidence, high risk of death – medRxiv (05/2020)
- [Preprint] The Chronic Kidney Disease and Acute Kidney Injury Involvement in COVID-19 Pandemic: A Systematic Review and Meta-analysis – medRxiv (05/2020)
- Peritoneal Dialysis During the Coronavirus 2019 (COVID-19) Pandemic: Acute Inpatient and Maintenance Outpatient Experiences – Kidney Medicine (05/2020)
- Outpatient Management of the Kidney Transplant Recipient during the SARS-CoV-2 Virus Pandemic – Clinical Journal of the American Society of Nephrology (05/2020)
- Impending Shortages of Kidney Replacement Therapy for COVID-19 Patients – Clinical Journal of the American Society of Nephrology (05/2020)
- Consensus recommendations for the care of children receiving chronic dialysis in association with the COVID-19 epidemic – Pediatric Nephrology (05/2020)
- Acute kidney injury in SARS-CoV-2 infected patients – Critical Care
- Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China – Kidney International (04/2020)
- Safeguarding the Maintenance Hemodialysis Patient Population during the Coronavirus Disease 19 Pandemic – Blood Purification (04/2020)
- Kidney disease is associated with in-hospital death of patients with COVID-19 – Kidney International (04/2020)
- COVID-19 and the Inpatient Dialysis Unit – Clinical Journal of the American Society of Nephrology (04/2020)
- On the Frontline of the COVID-19 Outbreak: Keeping Patients on Long-Term Dialysis Safe – Clinical Journal of the American Society of Nephrology (03/2020)
- CKD and Dialysis in the Time of COVID-19 – NephJC (03/2020)
- ERA-EDTA sharing Milan experience on coronavirus management in dialysis centres – Clinical Kidney Journal
- Mitigating Risk of COVID-19 in Dialysis Facilities – Clinical Journal of the American Society of Nephrology
COVID-19 Nephrology: This page will be updated as often as necessary and will be fixed in the right column on our homepage.
Management of Kidney Stones in 2020
20 Mar, 2020 | 10:54h | UTCManagement of Kidney Stones in 2020 – JAMA (free for a limited period)
Related Guidelines: Renal and ureteric stones: assessment and management – National Institute for Health and Care Excellence (free) AND Dietary and Pharmacologic Management to Prevent Recurrent Nephrolithiasis in Adults: A Clinical Practice Guideline From the American College of Physicians (free) AND Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement – Journal of Nephrology (free) AND Medical Management of Kidney Stones: AUA Guideline (free) AND Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART I (free) AND Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART II (free) AND The Urological Association of Asia clinical guideline for urinary stone disease – International Journal of Urology (free)
State of the Art Review: Management of ANCA Associated Vasculitis
19 Mar, 2020 | 10:54h | UTCManagement of ANCA associated vasculitis – The BMJ (free)
KDOQI Clinical Practice Guideline for Vascular Access
18 Mar, 2020 | 09:56h | UTC
Podcast: Hyperkalemia, Diet, K+ Binders, Exercise
17 Mar, 2020 | 08:40h | UTCSee also: Episode List
Observational Study Suggests Continuing ACE-I/ARBs in Patients with Declining kidney Function May Reduce Cardiovascular Risk Without Increased Risk of Progression to End-stage Kidney Disease
10 Mar, 2020 | 08:28h | UTCAssociation Between Renin-Angiotensin System Blockade Discontinuation and All-Cause Mortality Among Persons With Low Estimated Glomerular Filtration Rate – JAMA Internal Medicine (free for a limited period)
Editorial: Continuation of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in the Face of Kidney Disease Progression—Safe and Possibly Life Saving (free for a limited period)
Related Commentary on Twitter
Continuing ACE-I/ARB in patients with declining kidney function may provide cardiovascular and survival benefits without excessive harm of ESKD. https://t.co/h74imGHRbv
— JAMA Internal Medicine (@JAMAInternalMed) March 9, 2020
Randomized Trial: Effect of a Workplace-Based Multicomponent Intervention on Hypertension Control
6 Mar, 2020 | 10:21h | UTCEffect of a Workplace-Based Multicomponent Intervention on Hypertension Control: A Randomized Clinical Trial – JAMA Cardiology (free for a limited period)
Commentary: Blood pressure control achieved using workplace-based programs – News Medical (free)
Blood Pressure in Frail Older Adults: Associations with Cardiovascular Outcomes and All-cause Mortality
6 Mar, 2020 | 10:19h | UTCCommentary: Expert reaction to study looking at low blood pressure and mortality in older adults – Science Media Centre (free)
Related Commentary on Twitter
Important paper by Jane Masoli et al at Exeter. In over 75, BP <130/80 had higher mortality. In over 85s NO association high BP w mortality. Even BP>180!! https://t.co/F3KlOiRQxy pic.twitter.com/3168nRS2AX
— Lucy Pollock (@lucypgeridoc) March 5, 2020
Meta-Analysis: Watchful Waiting Strategy vs. Early Initiation of Renal Replacement Therapy in Critically Ill Patients with Acute Kidney Injury
5 Mar, 2020 | 10:25h | UTCRelated: Review: Renal Replacement Therapy in the Critical Care Setting (free resources)
Meta-Analysis: Effect of Reduction in Dietary Sodium on Blood Pressure Levels
28 Feb, 2020 | 08:35h | UTCCommentaries: Further evidence adds weight to call for urgent action on salt targets – George Institute for Global Health (free) AND Cutting salt likely to prevent future heart disease, even if you’re not at risk now – CNN (free)
Related Commentary on Twitter
Evidence shows that sodium reduction lowers blood pressure in both hypertensive and non-hypertensive individuals, with greater effects in high risk subsets, concludes new #BMJResearch https://t.co/Oh3aIj1W9d
— The BMJ (@bmj_latest) February 27, 2020
[Abstract Only] Meta-Analysis of Observational Studies Suggests No Benefit from Oral Anticoagulation in Patients With Atrial Fibrillation on Long-Term Dialysis
26 Feb, 2020 | 07:00h | UTCOral Anticoagulation for Patients With Atrial Fibrillation on Long-Term Dialysis – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Anticoagulation for Dialysis Patients with Atrial Fibrillation: No Benefit Seen – NEJM Journal Watch (free for a limited period)
Study: Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults with Hypertension
25 Feb, 2020 | 06:42h | UTCEvaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With Hypertension – JAMA Internal Medicine (free for a limited period)
Commentary: Antihypertensive Prescribing Cascades as High-Priority Targets for Deprescribing – JAMA Internal Medicine (free for a limited period)
Related Commentary on Twitter
Prescribing cascades occur when a second medicine is prescribed to counteract the effects of the first medicine. This @JAMAInternalMed article is the strongest empiric evidence I have seen that these cascades are very real #geriatrics https://t.co/KmJ2nhLlXM
— Ken Covinsky (@geri_doc) February 24, 2020
Review: NAFLD as a Driver of Chronic Kidney Disease
25 Feb, 2020 | 06:05h | UTCNAFLD as a driver of chronic kidney disease – Journal of Hepatology (free)
Practice Recommendations: Prescribing High-quality Goal-directed Peritoneal Dialysis
21 Feb, 2020 | 07:35h | UTC
Randomized Trial: Sodium Bicarbonate Prehydration Prior to Contrast-Enhanced Computed Tomography Does Not Prevent Postcontrast Acute Kidney Injury in Adults with Chronic Kidney Disease
18 Feb, 2020 | 08:18h | UTCRelated: ACR/NKF Consensus Statement: “The Risk of Acute Kidney Injury Developing in Patients with Reduced Kidney Function Following Exposure to Intravenous Iodinated Contrast Media has Been Overstated” (free statement and commentary) AND Another Study Questions the Association of Contrast Use and Acute Kidney Injury (studies on the subject)
Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence
18 Feb, 2020 | 08:24h | UTCEffect of salt substitution on community-wide blood pressure and hypertension incidence – Nature Medicine (free for a limited period)
Commentaries Before Publication at #ESCCongress: Community-based salt substitution programme lowers blood pressure – European Society of Cardiology (free) AND Community-Level Salt-Swapping Strategy Pays Dividends in Peru – TCTMD (free)
Related Commentary on Twitter
What happens when you replace salt with 25% KCl (+75% NaCl) in many villages in Peru?https://t.co/hL053MXjHq
A small reduction in blood pressure and 51% reduced risk of developing hypertension@NatureMedicine by @jjaimemiranda @cronicasperu
@CayetanoHeredia and colleagues pic.twitter.com/gqBtbJN47k— Eric Topol (@EricTopol) February 17, 2020
Large Observational Study Suggests Hydrochlorothiazide may be as Effective as Chlortalidone with Less Adverse Effects
18 Feb, 2020 | 08:17h | UTCComparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension – JAMA Internal Medicine (free for a limited period)
Commentary: Hypertension Treatments with Chlorthalidone vs HCTZ: Cardiac and Safety Outcomes – MedicalResearch.com (free)
Global, Regional, and National Burden of Chronic Kidney Disease
16 Feb, 2020 | 21:38h | UTCNews Release: Chronic kidney disease a ‘global killer in plain sight’ – Institute for Health Metrics and Evaluation (free)
Commentaries: The global burden of chronic kidney disease – The Lancet (free) AND Chronic kidney disease killing millions worldwide – News Medical (free) AND Chronic kidney disease kills more than 1M people annually worldwide – UPI (free)
Related Commentary on Twitter
NEW #GBDStudy provides latest data for global, regional, and national burden of chronic kidney disease, 1990–2017. In 2017, 1·2 million people died from chronic #kidneydisease, with global all-age mortality rate rising 41.5% between 1990 and 2017 @IHME_UW https://t.co/pxWenSGBfJ pic.twitter.com/nT0VQltWsj
— The Lancet (@TheLancet) February 14, 2020