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Internal Medicine

M-A | Antibiotics for preventing recurrent urinary tract infection.

4 Jul, 2022 | 12:17h | UTC

Antibiotics for Preventing Recurrent Urinary Tract Infection: Systematic Review and Meta-Analysis – Open Forum Infectious Diseases


Brief Review | Ventilator-associated pneumonia.

4 Jul, 2022 | 12:15h | UTC

Ventilator-associated pneumonia – Intensive Care Medicine (if the link is paywalled, try this one in PMC)

 

Commentary on Twitter


Review | Lowering and raising serum urate levels: off-label effects of commonly used medications.

4 Jul, 2022 | 12:10h | UTC

Lowering and Raising Serum Urate Levels: Off-Label Effects of Commonly Used Medications – Mayo Clinic Proceedings


How doctors manage conflicts with families of critically ill patients during conversations about end-of-life decisions in neonatal, pediatric, and adult intensive care.

4 Jul, 2022 | 12:13h | UTC

How doctors manage conflicts with families of critically ill patients during conversations about end-of-life decisions in neonatal, pediatric, and adult intensive care – Intensive Care Medicine


2022 Guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19.

1 Jul, 2022 | 11:50h | UTC

2022 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19 – The Lancet Oncology

Related:

Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy – Cochrane Library

American Society of Hematology 2021 guidelines for management of venous thromboembolism: prevention and treatment in patients with cancer – Blood Advances

Cancer-Associated Venous Thromboembolic Disease, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

Venous and Arterial Thromboembolism in Patients With Cancer: JACC: CardioOncology State-of-the-Art Review

 


Two new studies show no benefit of Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19.

1 Jul, 2022 | 11:49h | UTC

Study 1: Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial – The Lancet Haematology

Study 2: Thromboprophylactic low-molecular-weight heparin versus standard of care in unvaccinated, at-risk outpatients with COVID-19 (ETHIC): an open-label, multicentre, randomised, controlled, phase 3b trial – The Lancet Haematology

Commentaries:

Antithrombotic prophylaxis for symptomatic outpatients with COVID-19: less is consistently more – The Lancet Haematology

Antithrombotic Prophylaxis No Help in Outpatients With COVID — Two trials show no differences between patients who received enoxaparin vs standard of care – MedPage Today (free registration required)

 

Commentary on Twitter (thread – click for more)

 


Accuracy of rapid antigen vs. RT-PCR testing for SARS-CoV-2 infection in college athletes during prevalence of the Omicron variant.

1 Jul, 2022 | 11:39h | UTC

Accuracy of Rapid Antigen vs Reverse Transcriptase–Polymerase Chain Reaction Testing for SARS-CoV-2 Infection in College Athletes During Prevalence of the Omicron Variant – JAMA Network Open

 

Commentary on Twitter

 


Consensus for the definition, classification, diagnosis, and management of urticaria.

1 Jul, 2022 | 11:32h | UTC

Taiwanese dermatological association consensus for the definition, classification, diagnosis, and management of urticaria: A 2021 update – Journal of the Formosan Medical Association

 


Safety of empagliflozin in patients with Type 2 Diabetes and chronic kidney disease: pooled analysis of placebo-controlled clinical trials.

1 Jul, 2022 | 10:44h | UTC

Safety of Empagliflozin in Patients With Type 2 Diabetes and Chronic Kidney Disease: Pooled Analysis of Placebo-Controlled Clinical Trials – Diabetes Care

 


Life’s Essential 8: Updating and enhancing the AHA construct of cardiovascular health.

30 Jun, 2022 | 11:31h | UTC

Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association – Circulation

News Release: American Heart Association adds sleep to cardiovascular health checklist

Commentary: Sleep duration matters for heart health, according to new recommendations – CNN

Related Study: Status of Cardiovascular Health in US Adults and Children Using the American Heart Association’s New “Life’s Essential 8” Metrics: Prevalence Estimates from the National Health and Nutrition Examination Survey (NHANES), 2013-2018 – Circulation

 


Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis.

30 Jun, 2022 | 11:26h | UTC

Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis – The BMJ

 


RCT: Effects of early Empagliflozin initiation on diuresis and kidney function in patients with acute decompensated heart failure.

30 Jun, 2022 | 11:24h | UTC

Effects of Early Empagliflozin Initiation on Diuresis and Kidney Function in Patients With Acute Decompensated Heart Failure (EMPAG-HF) – Circulation

 


Cohort Study: Association of time elapsed since ischemic stroke with risk of recurrent stroke in older patients undergoing elective nonneurologic, noncardiac surgery.

30 Jun, 2022 | 11:16h | UTC

Association of Time Elapsed Since Ischemic Stroke With Risk of Recurrent Stroke in Older Patients Undergoing Elective Nonneurologic, Noncardiac Surgery – JAMA Surgery (free for a limited period)

Invited Commentary: Perioperative Stroke Risk Model—One Size Fits All? – JAMA Surgery

 


Secondary analysis of a RCT: Empagliflozin for heart failure with preserved left ventricular ejection fraction with and without diabetes.

30 Jun, 2022 | 10:58h | UTC

Empagliflozin for Heart Failure With Preserved Left Ventricular Ejection Fraction With and Without Diabetes – Circulation

Original Study: Empagliflozin in Heart Failure with a Preserved Ejection Fraction – New England Journal of Medicine

 


Brief Review: Update on prevention of intra-vascular accesses complications.

30 Jun, 2022 | 10:38h | UTC

Update on prevention of intra-vascular accesses complications – Intensive Care Medicine (if the link is paywalled, try this one)

 

Commentary on Twitter

 


Case-Control Study: Outcomes and risk factors for delayed-onset postoperative respiratory failure.

30 Jun, 2022 | 10:34h | UTC

Outcomes and risk factors for delayed-onset postoperative respiratory failure: a multi-center case-control study by the University of California Critical Care Research Collaborative (UC3RC) – BMC Anesthesiology

 


RCT: A 2-week interruption in methotrexate treatment doubles the antibody response to a COVID-19 booster vaccine.

29 Jun, 2022 | 12:10h | UTC

Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial – The Lancet Respiratory Medicine

News Releases:

Interrupting the treatment of vulnerable people on immune-suppressing medicines, doubles their antibody response to COVID-19 booster vaccination – University of Nottingham

Interrupting immune-suppressing treatment can boost COVID vaccine response – Imperial College London

Commentaries:

Improving COVID-19 vaccine immunogenicity by interrupting methotrexate treatment – The Lancet Respiratory Medicine

Covid-19: Pausing immune suppressing drugs enhances antibody response to boosters, study shows – The BMJ

Related Study: Two-week methotrexate discontinuation in patients with rheumatoid arthritis vaccinated with inactivated SARS-CoV-2 vaccine: a randomised clinical trial – Annals of Rheumatic Diseases

 

Commentary on Twitter

 


M-A: Comparison of mortality and hospital readmissions among patients receiving virtual ward transitional care vs. usual postdischarge care.

29 Jun, 2022 | 12:06h | UTC

Comparison of Mortality and Hospital Readmissions Among Patients Receiving Virtual Ward Transitional Care vs Usual Postdischarge Care: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


Review: Common hand conditions.

29 Jun, 2022 | 11:57h | UTC

Common Hand Conditions: A Review – JAMA (free for a limited period)

Audio Clinical Review: Diagnosis and Treatment of Common Hand Conditions

 


An analysis of SARS-CoV-2 vaccine reactogenicity: variation by type, dose, and history, severity, and recency of prior SARS-CoV-2 infection.

29 Jun, 2022 | 11:52h | UTC

An Analysis of SARS-CoV-2 Vaccine Reactogenicity: Variation by Type, Dose, and History, Severity, and Recency of Prior SARS-CoV-2 Infection – Open Forum Infectious Diseases

 


Guideline: Differential diagnosis of acute and chronic redness of the lower legs.

29 Jun, 2022 | 11:42h | UTC

S1 guideline: Differential diagnosis of acute and chronic redness of the lower legs – Journal of the German Society of Dermatology

 


Lipid guidelines for primary prevention.

29 Jun, 2022 | 11:31h | UTC

2022 Taiwan lipid guidelines for primary prevention – Journal of the Formosan Medical Association

 


Network meta-analysis: Dipeptidyl peptidase-4 inhibitors increase the risk of cholecystitis in patients with type 2 diabetes.

29 Jun, 2022 | 11:24h | UTC

Dipeptidyl peptidase-4 inhibitors and gallbladder or biliary disease in type 2 diabetes: systematic review and pairwise and network meta-analysis of randomised controlled trials – The BMJ

 


Pharmacological management of hypertrophic cardiomyopathy: from bench to bedside.

29 Jun, 2022 | 11:01h | UTC

Pharmacological Management of Hypertrophic Cardiomyopathy: From Bench to Bedside – Drugs

 


Retrospective Cohort Study: Atrial fibrillation after surgery is linked to an increased risk of hospitalization for heart failure.

29 Jun, 2022 | 10:52h | UTC

News Release: Atrial fibrillation after surgery is linked to an increased risk of hospitalization for heart failure – European Society of Cardiology

Original Study: Post-operative atrial fibrillation and risk of heart failure hospitalization – European Heart Journal

Editorial: Post-operative AF and heart failure hospitalizations: what remains hidden in patients undergoing surgery – European Heart Journal

 

Commentary on Twitter

 


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