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Internal Medicine

Monkeypox virus infection in humans across 16 countries — April–June 2022.

25 Jul, 2022 | 13:09h | UTC

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Commentary: Largest monkeypox study to date highlights new symptoms – CIDRAP

Related: WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

 

Commentary on Twitter

 


WHO declares global public health emergency over Monkeypox virus outbreak.

25 Jul, 2022 | 13:11h | UTC

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Related: Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

 


[PREPRINT] RCT | Inhaled fluticasone not beneficial for outpatients with Covid-19.

25 Jul, 2022 | 13:01h | UTC

Inhaled Fluticasone for Outpatient Treatment of Covid-19: A Decentralized, Placebo-controlled, Randomized, Platform Clinical Trial – medRxiv

News Release: Study finds no benefit to taking fluticasone furoate for COVID-19 symptoms – Duke Clinical Research Institute

Commentary: Asthma Drug Fluticasone Fails as Potential COVID-19 Treatment – HealthDay

 


Retrospective Cohort Study | Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old.

25 Jul, 2022 | 13:03h | UTC

Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old: A nationwide, retrospective cohort study in Sweden – The Lancet Regional Health Europe

Related:

Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada: test negative design study – The BMJ

Association of Receipt of the Fourth BNT162b2 Dose With Omicron Infection and COVID-19 Hospitalizations Among Residents of Long-term Care Facilities – JAMA Internal Medicine

Short term, relative effectiveness of four doses versus three doses of BNT162b2 vaccine in people aged 60 years and older in Israel: retrospective, test negative, case-control study – The BMJ

Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting – New England Journal of Medicine

 


Cohort Study | Fatty liver disease is not associated with increased mortality in the elderly.

25 Jul, 2022 | 12:59h | UTC

Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study – Hepatology

Commentary: Fatty liver disease may not affect mortality risk in elderly patients – ACP Gastroenterology

 


Cohort Study | Taiwan’s nationwide Hepatitis B vaccination and antiviral therapy program reduced end-stage liver disease burden.

25 Jul, 2022 | 12:54h | UTC

Association of Nationwide Hepatitis B Vaccination and Antiviral Therapy Programs With End-Stage Liver Disease Burden in Taiwan – JAMA Network Open

 

Commentary on Twitter

 


M-A | Antihistamines are better than benzodiazepines for symptomatic control in patients with acute vertigo.

25 Jul, 2022 | 12:52h | UTC

Efficacy of Benzodiazepines or Antihistamines for Patients With Acute Vertigo: A Systematic Review and Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)

Commentary: Antihistamines Appear More Effective Than Benzodiazepines for Acute Vertigo, Meta-Analysis Finds – NeurologyToday

 

Commentary on Twitter

 


Guideline Synopsis | Therapy for mild to moderate asthma.

22 Jul, 2022 | 11:48h | UTC

Therapy for Mild to Moderate Asthma – JAMA (free for a limited period)

Original Guideline: 2022 GINA Report, Global Strategy for Asthma Management and Prevention

Related: Global Initiative for Asthma (GINA) Strategy 2021 – Executive summary and rationale for key changes – European Respiratory Journal

 


Perspective | Achieving diagnostic excellence for cancer: symptom detection as a partner to screening.

22 Jul, 2022 | 11:44h | UTC

Achieving Diagnostic Excellence for Cancer: Symptom Detection as a Partner to Screening – JAMA (free for a limited period)

 


Single-center RCT | A procalcitonin-based algorithm to guide antibiotic use in patients with acute pancreatitis.

22 Jul, 2022 | 11:40h | UTC

A procalcitonin-based algorithm to guide antibiotic use in patients with acute pancreatitis (PROCAP): a single-centre, patient-blinded, randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


An approach to the management of diabetes mellitus in cirrhosis: a primer for the hepatologist.

22 Jul, 2022 | 11:26h | UTC

An Approach to the Management of Diabetes Mellitus in Cirrhosis: A Primer for the Hepatologist – Journal of Clinical and Experimental Hepatology

 


Analysis | Fiber intake for optimal health: how can healthcare professionals support people to reach dietary recommendations?

21 Jul, 2022 | 13:17h | UTC

Fibre intake for optimal health: how can healthcare professionals support people to reach dietary recommendations? – The BMJ

 


Retrospective cohort study | Impact of ethnicity on the accuracy of measurements of oxygen saturations.

21 Jul, 2022 | 13:15h | UTC

Impact of ethnicity on the accuracy of measurements of oxygen saturations: A retrospective observational cohort study – eClinicalMedicine

Related:

Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19 – JAMA Internal Medicine

Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review – The Lancet Digital Health

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT

Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration

 


With monkeypox spreading globally, many experts believe the virus can’t be contained.

21 Jul, 2022 | 13:12h | UTC

With monkeypox spreading globally, many experts believe the virus can’t be contained – STAT

Related:

A Primer on Monkeypox Virus for Obstetrician–Gynecologists: Diagnosis, Prevention, and Treatment – Obstetrics & Gynecology

Diagnosis, Prevention, and Treatment of Monkeypox – JAMA

7 of your most pressing monkeypox vaccine questions, answered – Vox

How contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic

Prevention and Treatment of Monkeypox – Drugs

Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP

No room for complacency – World Health Organization

Multi-country monkeypox outbreak: situation update – World Health Organization

Monkeypox Genital Lesions – New England Journal of Medicine

Monkeypox: Africa CDC Demands Equal Treatment in Global Allocation of Limited Vaccine Doses – Health Policy Watch

Monkeypox vaccination begins — can the global outbreaks be contained? – Nature

Incubation period for monkeypox: Estimates from the Netherlands.

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Rename monkeypox strains to remove geographic stigma, researchers say – Science

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

 


Review | Clinical implications, evaluation, and management of hyponatremia in cirrhosis.

21 Jul, 2022 | 12:53h | UTC

Clinical Implications, Evaluation, and Management of Hyponatremia in Cirrhosis – Journal of Clinical and Experimental Hepatology

 


M-A | Loop diuretics in adult intensive care patients with fluid overload.

21 Jul, 2022 | 12:56h | UTC

Loop diuretics in adult intensive care patients with fluid overload: a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis – Annals of Intensive Care

 


Review | Fatigue in cirrhosis.

21 Jul, 2022 | 12:52h | UTC

Fatigue in Cirrhosis – Journal of Clinical and Experimental Hepatology

 


Review | Therapeutic advances in alcohol-associated hepatitis.

21 Jul, 2022 | 12:36h | UTC

Therapeutic advances in alcohol-associated hepatitis – Journal of Hepatology

Related: Liver Transplantation in Alcohol-related Liver Disease and Alcohol-related Hepatitis – Journal of Clinical and Experimental Hepatology

 

Commentary on Twitter

 


Open-label RCT | Moderate-intensity statin plus ezetimibe is noninferior to high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease.

20 Jul, 2022 | 12:32h | UTC

Long-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease (RACING): a randomised, open-label, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

 


AHA Scientific Statement | Polygenic risk scores for cardiovascular disease.

20 Jul, 2022 | 12:31h | UTC

Polygenic Risk Scores for Cardiovascular Disease: A Scientific Statement From the American Heart Association – Circulation

 


High-sensitivity cardiac troponin and the 2021 AHA/ACC Guidelines for the evaluation and diagnosis of acute chest pain.

20 Jul, 2022 | 12:29h | UTC

High-Sensitivity Cardiac Troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guidelines for the Evaluation and Diagnosis of Acute Chest Pain – Circulation (free for a limited period)

Summary: High-Sensitivity Cardiac Troponin and the 2021 Guidelines for Acute Chest Pain – American College of Cardiology

 

Commentary on Twitter

 


Guideline | Neurological manifestations of post-COVID-19 syndrome.

20 Jul, 2022 | 12:18h | UTC

Neurological manifestations of post-COVID-19 syndrome S1-guideline of the German society of neurology – Neurological Research and Practice

 


Top 20 research studies of 2021 for primary care physicians.

20 Jul, 2022 | 12:24h | UTC

Top 20 Research Studies of 2021 for Primary Care Physicians – American Family Physician (PDF)

Related: Top studies of 2021 relevant to primary care: From the PEER team – Canadian Family Physician

 


A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics.

20 Jul, 2022 | 12:27h | UTC

A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics – American Journal of Obstetrics and Gynecology

Commentary: Study suggests COVID-19 vaccination may be associated with short-term changes in usual menstrual cycle length – News Medical

 


A primer on Monkeypox virus for obstetrician-gynecologists: diagnosis, prevention, and treatment.

20 Jul, 2022 | 12:22h | UTC

A Primer on Monkeypox Virus for Obstetrician–Gynecologists: Diagnosis, Prevention, and Treatment – Obstetrics & Gynecology

Related:

With monkeypox spreading globally, many experts believe the virus can’t be contained – STAT

Diagnosis, Prevention, and Treatment of Monkeypox – JAMA

7 of your most pressing monkeypox vaccine questions, answered – Vox

How contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic

Prevention and Treatment of Monkeypox – Drugs

Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP

No room for complacency – World Health Organization

Multi-country monkeypox outbreak: situation update – World Health Organization

Monkeypox Genital Lesions – New England Journal of Medicine

Monkeypox: Africa CDC Demands Equal Treatment in Global Allocation of Limited Vaccine Doses – Health Policy Watch

Monkeypox vaccination begins — can the global outbreaks be contained? – Nature

Incubation period for monkeypox: Estimates from the Netherlands.

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Rename monkeypox strains to remove geographic stigma, researchers say – Science

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

 


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