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Internal Medicine

M-A of randomized trials | Effectiveness and cost-effectiveness of oral nutritional supplements in frail older people who are malnourished or at risk of malnutrition.

20 Sep, 2022 | 13:24h | UTC

Effectiveness and cost-effectiveness of oral nutritional supplements in frail older people who are malnourished or at risk of malnutrition: a systematic review and meta-analysis – The Lancet Health Longevity

Invited Commentary: Do oral nutritional supplements effectively reduce malnutrition or its adverse outcomes in older people with frailty? – The Lancet Health Longevity

 

Case report and brief review | Severe thrombotic complications secondary to antiphospholipid syndrome and undiagnosed systemic lupus erythematosus.

20 Sep, 2022 | 13:17h | UTC

Severe thrombotic complications secondary to antiphospholipid syndrome and undiagnosed systemic lupus erythematosus – Canadian Medical Association Journal

 

Cohort Study | Seven healthy lifestyle habits linked to reduced risk of dementia in people with diabetes.

19 Sep, 2022 | 12:45h | UTC

Association of Combined Healthy Lifestyle Factors With Incident Dementia in Patients With Type 2 Diabetes – Neurology (link to abstract – $ for full-text)

News Release: Seven healthy lifestyle habits may reduce dementia risk for people with diabetes – American Academy of Neurology

Commentary: Lifestyle Factors May Cut Dementia Risk in Patients With Diabetes – HealthDay

 

Cluster RCT | Effects of real-time prescription benefit recommendations on patient out-of-pocket costs.

19 Sep, 2022 | 12:47h | UTC

Effects of Real-time Prescription Benefit Recommendations on Patient Out-of-Pocket Costs: A Cluster Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Invited Commentary: Real-time Prescription Benefit Tools—The Promise and Peril – JAMA Internal Medicine (free for a limited period)

 

Commentary on Twitter

 

Diet and irritable bowel syndrome: an update from a UK consensus meeting.

19 Sep, 2022 | 12:42h | UTC

Diet and irritable bowel syndrome: an update from a UK consensus meeting – BMC Medicine

Related:

M-A | Efficacy of a restrictive diet in irritable bowel syndrome.

Diet or medication in primary care patients with IBS: the DOMINO study – a randomised trial supported by the Belgian Health Care Knowledge Centre (KCE Trials Programme) and the Rome Foundation Research Institute – Gut

AGA Clinical Practice Update on the Role of Diet in Irritable Bowel Syndrome: Expert Review – Gastroenterology

RCT: Efficacy and acceptability of dietary therapies in non-constipated irritable bowel syndrome: a randomized trial of traditional dietary advice, the low FODMAP diet and the gluten-free diet.

10 mistakes in dietary management of irritable bowel syndrome and how to avoid them.

Supplement: Irritable bowel syndrome and related conditions.

RCT: FODMAPs, but not gluten, elicit modest symptoms of irritable bowel syndrome.

RCT: Among patients with diarrhea-predominant irritable bowel syndrome, a low FODMAP diet achieved earlier symptomatic improvements in stool frequency and excessive wind.

British Society of Gastroenterology guidelines on the management of irritable bowel syndrome

Guidelines for the treatment of irritable bowel syndrome

ACG Clinical Guideline: Management of irritable bowel syndrome

M-A: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome

 

The Lancet Commission on lessons for the future from the COVID-19 pandemic – “a massive global failure.”

16 Sep, 2022 | 13:03h | UTC

Homepage: The Lancet COVID-19 Commission

The Lancet Commission on lessons for the future from the COVID-19 pandemic

Editorial: COVID-19: the case for prosociality

News Release: New report details “massive global failures” of COVID-19 response, calls for improved multilateral cooperation to end pandemic and effectively manage future global health threats – The Lancet

Infographic: COVID-19 response: a massive global failure

Commentaries:

WHO responds to The Lancet COVID-19 Commission – World Health Organization

Covid-19: Commission describes “massive global failures” of pandemic response – The BMJ

Covid-19 death toll is a tragedy and ‘massive global failure at multiple levels,’ Lancet commission says – CNN

Lancet Commission on COVID-19 response: ‘Massive global failure’ – CIDRAP

 

Update | Management of hepatorenal syndrome in liver cirrhosis.

19 Sep, 2022 | 12:27h | UTC

Management of hepatorenal syndrome in liver cirrhosis: a recent update – Therapeutic Advances in Gastroenterology

 

Guideline Synopsis | AHA/ACC Guideline for the management of heart failure.

16 Sep, 2022 | 13:01h | UTC

Management of Heart Failure – JAMA (free for a limited period)

Original Article: #ACC22 – 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

 

The Lancet Commission | Towards the elimination of chronic obstructive pulmonary disease.

16 Sep, 2022 | 13:02h | UTC

Homepage: Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission – The Lancet

Commission: Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission

Editorial: COPD: from an end-stage disease to lifelong lung health

Invited Commentary: Classification of COPD: fostering prevention and precision medicine in the Lancet Commission on COPD

Commentary: Proposed classification of COPD according to major risk factors – News Medical

 

AHA Scientific Statement | Management of patients at risk for and with left ventricular thrombus.

16 Sep, 2022 | 13:00h | UTC

Management of Patients at Risk for and With Left Ventricular Thrombus: A Scientific Statement From the American Heart Association – Circulation

 

Study | The specificity and positive predictive value of high-sensitivity cardiac troponin I for the diagnosis of myocardial infarction are reduced in older individuals.

16 Sep, 2022 | 12:57h | UTC

Influence of Age on the Diagnosis of Myocardial Infarction – Circulation

 

Review | Obesity and contraceptive use: impact on cardiovascular risk.

16 Sep, 2022 | 12:53h | UTC

Obesity and contraceptive use: impact on cardiovascular risk – ESC Heart Failure

News Release: Combined birth control pill linked with increased risk of blood clots in obese women – European Society of Cardiology

 

RCT | In patients with acute pancreatitis, early aggressive hydration resulted in a higher incidence of fluid overload without improvement in clinical outcomes.

15 Sep, 2022 | 13:15h | UTC

Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis – New England Journal of Medicine (link to abstract – $ for full-text)

 

RCT | Effects of cocoa extract and a multivitamin on cognitive function.

15 Sep, 2022 | 13:14h | UTC

Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial – Alzheimer’s & Dementia

Commentary: Daily multivitamins improved the brain function of seniors in a trial — but plenty of questions remain – STAT

 

Cohort Study | Patients diagnosed with diabetes by oral glucose tolerance test without elevated HbA1c had similar cardiovascular and renal disease risks as those without diabetes.

15 Sep, 2022 | 13:12h | UTC

Risk of Macrovascular and Microvascular Disease in Diabetes Diagnosed Using Oral Glucose Tolerance Test With and Without Confirmation by Hemoglobin A1c: The Whitehall II Cohort Study – Circulation

Commentary: Patients diagnosed by OGTT without elevated HbA1c had similar CV, renal disease risks as those without diabetes – ACP Diabetes

 

Commentary on Twitter

 

New research estimates the overall disease burden of genetic risk factors.

15 Sep, 2022 | 13:13h | UTC

News Release: New research estimates the overall disease burden of genetic risk factors – University of Helsinki

Original Study: Genetic risk factors have a substantial impact on healthy life years – Nature Medicine

 

Commentaries on Twitter

 

RCT | Effect of different itraconazole dosing regimens on cure rates, treatment duration, safety, and relapse rates in adult patients with tinea corporis/cruris.

15 Sep, 2022 | 13:10h | UTC

Effect of Different Itraconazole Dosing Regimens on Cure Rates, Treatment Duration, Safety, and Relapse Rates in Adult Patients With Tinea Corporis/Cruris: A Randomized Clinical Trial – JAMA Dermatology (free for a limited period)

 

Commentary on Twitter

 

Cohort Study | Long-term outcomes among men undergoing active surveillance for prostate cancer.

15 Sep, 2022 | 13:11h | UTC

Long-term Outcomes Among Men Undergoing Active Surveillance for Prostate Cancer in Sweden – JAMA Network Open

Invited Commentary: Exploring the Long-term Outcomes of Active Surveillance Among Men With Prostate Cancer—Best for Whom? – JAMA Network Open

 

Consensus recommendations for the use of Automated Insulin Delivery (AID) technologies in clinical practice.

15 Sep, 2022 | 13:06h | UTC

Consensus Recommendations for the Use of Automated Insulin Delivery (AID) Technologies in Clinical Practice – Endocrine Reviews

 

German guidelines on non-alcoholic fatty liver disease.

15 Sep, 2022 | 13:07h | UTC

Updated S2k Clinical Practice Guideline on Non-alcoholic Fatty Liver Disease (NAFLD) issued by the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS) – Zeitschrift für Gastroenterologie

Related:

AGA Clinical Practice Update | Diagnosis and management of nonalcoholic fatty liver disease in lean individuals.

Quality standards for the management of non-alcoholic fatty liver disease (NAFLD): consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology NAFLD Special Interest Group – The Lancet Gastroenterology & Hepatology (free registration required)

Nonalcoholic Fatty Liver Disease and Cardiovascular Risk: A Scientific Statement From the American Heart Association – Arteriosclerosis, Thrombosis, and Vascular Biology

Advancing the global public health agenda for NAFLD: a consensus statement – Nature Reviews Gastroenterology & Hepatology

Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty Liver Disease – Gastroenterology

Non-alcoholic fatty liver disease: A patient guideline – JHEP Reports

 

Systematic Review | Association of HIV infection with cardiovascular pathology based on advanced cardiovascular imaging.

15 Sep, 2022 | 13:02h | UTC

Association of HIV Infection With Cardiovascular Pathology Based on Advanced Cardiovascular Imaging: A Systematic Review – JAMA (free for a limited period)

Editorial: HIV, Subclinical Cardiovascular Disease, and Clinical Progression: Insights From Immunologic Heterogeneity – JAMA (free for a limited period)

 

Cohort Study | A 7-year study of the durability of improvements in pain, physical function, and work productivity after Roux-en-Y gastric bypass and sleeve gastrectomy.

15 Sep, 2022 | 13:03h | UTC

A 7-Year Study of the Durability of Improvements in Pain, Physical Function, and Work Productivity After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy – JAMA Network Open

News Release: Beyond weight loss: Improvements in pain, mobility persist long after bariatric surgery – University of Pittsburgh

Author Interview: Long-term Changes in Pain, Physical Function, and Work Productivity After Bariatric Surgery – JAMA

 

Study finds a higher complication rate after acute coronary syndrome in patients with rheumatic immune‐mediated inflammatory diseases.

15 Sep, 2022 | 13:01h | UTC

Outcomes Following Acute Coronary Syndrome in Patients With and Without Rheumatic Immune‐Mediated Inflammatory Diseases – Journal of the American Heart Association

News Release: Study finds higher complication rate after heart attack in people with autoimmune disease – American Heart Association

 

Review | Postoperative acute kidney injury.

15 Sep, 2022 | 13:00h | UTC

Postoperative AKI – Clinical Journal of the American Society of Nephrology

 

Study | Vitamin D3 and omega-3 fatty acids not helpful in reducing the risk of frailty.

14 Sep, 2022 | 13:20h | UTC

News Release: Vitamin D3 and omega-3 fatty acids not helpful in reducing risk of frailty – Brigham and Women’s Hospital

Original Study: Effect of Vitamin D3 and Omega-3 Fatty Acid Supplementation on Risk of Frailty: An Ancillary Study of a Randomized Clinical Trial – JAMA Network Open

Invited Commentary: There Is No Magic Pill to Prevent Frailty—You Still Have to Eat Your Vegetables – JAMA Network Open

 

Commentary on Twitter

 

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