Internal Medicine
Guideline Synopsis | Diabetes management in chronic kidney disease
10 Jan, 2023 | 14:52h | UTCCommentary: Layered Approach Recommended for Patients With Diabetes, CKD – HealthDay
Original Guideline: KDIGO 2022 Clinical practice guideline for diabetes management in chronic kidney disease.
RCT | Effect of prescriber notifications of patient’s fatal overdose on opioid prescribing at 4 to 12 months
10 Jan, 2023 | 14:50h | UTC
Commentary on Twitter
Letters notifying clinicians of a patient's fatal overdose reduced opioid prescribing up to one year after receiving the letter. https://t.co/cEU1inH9lE
— JAMA Network Open (@JAMANetworkOpen) January 6, 2023
Diagnostic accuracy study | Home waking salivary cortisone to screen for adrenal insufficiency
10 Jan, 2023 | 14:47h | UTCHome Waking Salivary Cortisone to Screen for Adrenal Insufficiency – NEJM Evidence
Commentary: At-home saliva test to diagnose adrenal insufficiency makes a difference to patients’ health – News Medical
Commentary on Twitter
This prospective study tested use of home waking salivary cortisone levels to predict adrenal insufficiency. Salivary cortisone had diagnostic accuracy similar to that of a standard adrenocorticotropin (ACTH) stimulation test. https://t.co/EYEBppBN7y#EndoTwitter #MedTwitter pic.twitter.com/RsKvnCHrUQ
— NEJM Evidence (@NEJMEvidence) January 6, 2023
M-A | Association of hearing aids and cochlear implants with cognitive decline and dementia
10 Jan, 2023 | 14:43h | UTCAssociation of Hearing Aids and Cochlear Implants With Cognitive Decline and Dementia: A Systematic Review and Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)
Commentary: Review Links Hearing Aid Devices With Reduced Cognitive Decline – HealthDay
Related: Dementia and hearing-aid use: a two-way street – Age and Ageing
WHO Interim Guidance | Surveillance, case investigation and contact tracing for mpox (monkeypox)
10 Jan, 2023 | 14:45h | UTC
Dementia and hearing-aid use: a two-way street
10 Jan, 2023 | 14:42h | UTCDementia and hearing-aid use: a two-way street – Age and Ageing
Related: Association of Hearing Aids and Cochlear Implants With Cognitive Decline and Dementia: A Systematic Review and Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)
Consensus Paper | Antipsychotic medication deprescribing among adult patients with critical illness
10 Jan, 2023 | 14:37h | UTC
Commentary on Twitter
#CritCareExplore @SCCM Prescribing recommendations in ICU patients: limit antipsychotics to those with hyperactive delirium, at risk of harm to self/others or w/ care impacts. @n_jaworska@kiramakuk@KarlaKrewulak@dan_niven@lisa_burry@geetamehta0 @kmfiest https://t.co/73GUvrfJls pic.twitter.com/TbjbnGxD8Y
— Critical Care Explorations (@CritCareExplore) December 4, 2022
Podcast | Endocrine emergencies
10 Jan, 2023 | 14:32h | UTC#372 Endocrine Emergencies featuring Dr. Sara Markley Webster – The Curbsiders
M-A | Prospective association of daily steps with cardiovascular disease
10 Jan, 2023 | 14:29h | UTCProspective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis – Circulation (link to abstract – $ for full-text)
Commentaries:
CVD Benefits of Activity Seen Below Widely Quoted Step Goal in Older Adults – TCTMD
Heart health tip for older adults in 2023: Step it up a bit – University of Massachusetts Amherst
Commentary on Twitter
#OriginalResearch: In a meta-analysis of 8 studies, 6,000 to 9,000 steps/day was associated with 40% to 50% lower risk of CVD among older adults #AHAJournals https://t.co/fEA1EFyhTI pic.twitter.com/T6LXFGZoVb
— Circulation (@CircAHA) December 21, 2022
Podcast | Diagnosis and management of ADHD in adults
10 Jan, 2023 | 14:31h | UTC#374 ADHD with Dr. Kevin Simon – The Curbsiders
Review | Home monitoring in interstitial lung diseases
10 Jan, 2023 | 14:06h | UTCHome monitoring in interstitial lung diseases – The Lancet Respiratory Diseases
Atypical ulcers: a stepwise approach for clinicians
10 Jan, 2023 | 14:00h | UTCAtypical Ulcers: A Stepwise Approach for Clinicians – Wounds
ACP Guideline | Pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults
9 Jan, 2023 | 14:59h | UTCSummary for Patients: Pharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults
WHO updates recommendations on HPV vaccination schedule
9 Jan, 2023 | 14:57h | UTCNews Release: WHO updates recommendations on HPV vaccination schedule – World Health Organization
Guideline: Human papillomavirus vaccines: WHO position paper, December 2022 – World Health Organization
Commentaries:
WHO supports 1-dose HPV vaccine strategy – CIDRAP
Commentary on Twitter
🆕 WHO has revised its recommendations on possible schedules for human papillomavirus (#HPV) vaccines & now recommends:
👉1 or 2-doses for girls & women aged 9-20
👉2 doses with a 6-month interval for women 21+https://t.co/m0KZyH6sPR pic.twitter.com/W4PeS4raV9— World Health Organization (WHO) (@WHO) December 21, 2022
RCT | VV116 vs. Nirmatrelvir–Ritonavir for oral treatment of Covid-19
9 Jan, 2023 | 14:50h | UTCVV116 versus Nirmatrelvir–Ritonavir for Oral Treatment of Covid-19 – New England Journal of Medicine
Commentaries:
Study could pave way for new antiviral, as China grapples with Covid wave – STAT
Chinese oral COVID-19 drug equally effective with Paxlovid: study
VV116 Noninferior to Nirmatrelvir-Ritonavir for COVID-19 – HealthDay
Commentary on Twitter
In a Chinese trial involving participants with symptomatic mild-to-moderate Covid-19, VV116 (an oral analogue of remdesivir) was noninferior to nirmatrelvir–ritonavir with respect to the time to sustained clinical recovery.
Read the full study: https://t.co/zckTB3Rvb9 pic.twitter.com/0TVF7hEXjP
— NEJM (@NEJM) December 28, 2022
Guideline | Treatment of hypercalcemia of malignancy in adults
9 Jan, 2023 | 14:46h | UTCNews Release: Experts provide first framework for treating hypercalcemia of malignancy in adults – News Medical
Scientists tie third clinical trial death to experimental Alzheimer’s drug
9 Jan, 2023 | 14:47h | UTCScientists tie third clinical trial death to experimental Alzheimer’s drug – Science
Related: RCT | Lecanemab slows cognitive decline in early Alzheimer’s disease but raises safety concerns.
Consensus Guideline | Management of the perioperative patient on cannabis and cannabinoids
9 Jan, 2023 | 14:43h | UTC
Commentary on Twitter
https://twitter.com/ASRA_Society/status/1610269709374554114
The year in cardiovascular medicine 2022: the top 10 papers in acute cardiac care and ischemic heart disease
9 Jan, 2023 | 14:28h | UTC
Commentary on Twitter
The Year in Cardiovascular Medicine 2022 series: the Top 10 papers in Cardiovascular Imaging https://t.co/OVJxxYu71p@escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes #CVD #cvimaging @chiarabd @NAjmoneMarsan pic.twitter.com/sooF0bz3LN
— European Society of Cardiology Journals (@ESC_Journals) January 2, 2023
The year in cardiovascular medicine 2022: the top 10 papers in dyslipidemias
9 Jan, 2023 | 14:26h | UTC
Commentary on Twitter
The Year in Cardiovascular Medicine 2022 series: the Top 10 papers in Dyslipidaemia https://t.co/jpkqgt4Hf1 @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes #CVD #dyslipidemia pic.twitter.com/UBfKy45mAu
— European Society of Cardiology Journals (@ESC_Journals) January 2, 2023
The year in cardiovascular medicine 2022: the top 10 papers in heart failure and cardiomyopathies
9 Jan, 2023 | 14:10h | UTC
Commentary on Twitter
The Year in Cardiovascular Medicine 2022 series: the Top 10 papers in Heart Failure and Cardiomyopathies https://t.co/w6opcMPcBa@escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes #HeartFailure #Cardiomyopathies pic.twitter.com/UrrX2LUQdI
— European Society of Cardiology Journals (@ESC_Journals) January 2, 2023
The year in cardiovascular medicine 2022: the top 10 papers in arrhythmias
9 Jan, 2023 | 14:19h | UTCThe year in cardiovascular medicine 2022: the top 10 papers in arrhythmias – European Heart Journal
Commentary on Twitter
The Year in Cardiovascular Medicine 2022 series: the Top 10 papers in Arrhythmias https://t.co/D3GM1l8TgW@escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes #CVD #arrhythmias pic.twitter.com/kxXqyEx8KM
— European Society of Cardiology Journals (@ESC_Journals) January 2, 2023
RCT | Chlorthalidone (12.5-25 mg) and Hydrochlorothiazide (25-50 mg) are similarly effective for the prevention of CVD in hypertensive patients.
16 Dec, 2022 | 13:49h | UTCChlorthalidone vs. Hydrochlorothiazide for Hypertension–Cardiovascular Events – New England Journal of Medicine (link to abstract – $ for full-text)
Related (news release and commentaries before publication): RCT | Chlortalidone and Hydrochlorothiazide resulted in similar reductions of CVD in older patients with hypertension.
Commentary on Twitter
Patients 65 years or older with hypertension who switched from chlorthalidone to hydrochlorothiazide did not have fewer major cardiovascular events or non–cancer-related deaths than those who continued receiving hydrochlorothiazide. https://t.co/9xAiSZzxio pic.twitter.com/bIVOOiVDve
— NEJM (@NEJM) December 14, 2022
Updated Guidance | Acute, periprocedural and long-term antithrombotic therapy in older adults.
16 Dec, 2022 | 13:51h | UTCCommentary: Antithrombotic Therapy in Older Adults: Key Points – American College of Cardiology
Cohort Study | Association between bariatric surgery and alcohol use–related hospitalization and all-cause mortality.
16 Dec, 2022 | 13:44h | UTCAssociation Between Bariatric Surgery and Alcohol Use–Related Hospitalization and All-Cause Mortality in a Veterans Affairs Cohort – JAMA Surgery (link to abstract – $ for full-text)