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Internal Medicine

RCT | Colistin monotherapy vs. combination therapy for carbapenem-resistant organisms

13 Jan, 2023 | 13:36h | UTC

Colistin Monotherapy versus Combination Therapy for Carbapenem-Resistant Organisms – NEJM Evidence

Commentary: Colistin Alone or with Meropenem: Is More Better? – NEJM Journal Watch

Related: Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial – The Lancet

 


Retrospective Study | Clinical features and management of individuals admitted to hospital with monkeypox

13 Jan, 2023 | 13:33h | UTC

Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study – The Lancet Infectious Diseases

 


Peritoneal dialysis prescription and adequacy in clinical practice: Core Curriculum 2023

13 Jan, 2023 | 13:31h | UTC

Peritoneal Dialysis Prescription and Adequacy in Clinical Practice: Core Curriculum 2023 – American Journal of Kidney Diseases

 

Commentary on Twitter

 


Report | Obstacles and opportunities in managing coexisting obesity and CKD

13 Jan, 2023 | 13:30h | UTC

Obstacles and Opportunities in Managing Coexisting Obesity and CKD: Report of a Scientific Workshop Cosponsored by the National Kidney Foundation and The Obesity Society – American Journal of Kidney Diseases

 


Study suggests delivering high concentrations of antibiotics into the implantation site is feasible for infections in implanted CV electronic devices

13 Jan, 2023 | 13:26h | UTC

Regional Antibiotic Delivery for Implanted Cardiovascular Electronic Device Infections – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: 

Direct Delivery of Antibiotics to CV Device Pocket Infections Appears Promising – TCTMD

Regional Antibiotics for Implanted Cardiovascular Electronic Device Infections – American College of Cardiology

 


Cohort Study | Antibiotic exposure linked to increased risk of inflammatory bowel disease

13 Jan, 2023 | 13:25h | UTC

Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study – Gut

News Release: Frequent use of antibiotics may heighten inflammatory bowel disease risk in over 40s – BMJ Newsroom

Commentaries: 

Antibiotics may increase risk of inflammatory bowel disease, study finds – CIDRAP

Antibiotic Exposure Positively Linked to IBD Development – HealthDay

 

Commentary on Twitter

 


SR | Protein restriction for diabetic kidney disease

13 Jan, 2023 | 13:21h | UTC

Protein restriction for diabetic kidney disease – Cochrane Library

Summary: Low protein diets for adults with diabetic kidney disease – Cochrane Library

 


RCT | A 24-week, all-oral regimen for rifampin-resistant tuberculosis

12 Jan, 2023 | 13:27h | UTC

A 24-Week, All-Oral Regimen for Rifampin-Resistant Tuberculosis – New England Journal of Medicine

Commentary: Trial results show superiority of shorter, all-oral treatment for drug-resistant TB – CIDRAP

 


Review | The pathogenesis and therapeutic strategies of heat stroke-induced liver injury

13 Jan, 2023 | 13:07h | UTC

The pathogenesis and therapeutic strategies of heat stroke-induced liver injury – Critical Care

 


WHO consolidated guidelines on tuberculosis | Drug-resistant tuberculosis treatment, 2022 update

12 Jan, 2023 | 13:30h | UTC

WHO consolidated guidelines on tuberculosis. Module 4: treatment – drug-resistant tuberculosis treatment, 2022 update – World Health Organization

See also:

WHO consolidated guidelines on tuberculosis: module 1: prevention: tuberculosis preventive treatment

WHO consolidated guidelines on tuberculosis: module 2: screening: systematic screening for tuberculosis disease

WHO consolidated guidelines on tuberculosis: module 3: diagnosis: rapid diagnostics for tuberculosis detection, 2021 update

WHO consolidated guidelines on tuberculosis: module 5: management of tuberculosis in children and adolescents

 


RCT | Early treatment with Molnupiravir did not reduce hospitalizations in high-risk adults with COVID-19

12 Jan, 2023 | 13:24h | UTC

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial – The Lancet

Commentaries: 

Molnupiravir does not reduce COVID-19 hospitalisations or deaths in vaccinated, high risk people – National Institute for Health and Care Research

Molnupiravir doesn’t cut Omicron hospitalization, death but can speed recovery – CIDRAP

 


An evidence and consensus-based definition of “Second Victim”

12 Jan, 2023 | 13:21h | UTC

An Evidence and Consensus-Based Definition of Second Victim: A Strategic Topic in Healthcare Quality, Patient Safety, Person-Centeredness and Human Resource Management – International Journal of Environmental Research and Public Health

 


RCT | Second-line levofloxacin-based quadruple therapy vs. bismuth-based quadruple therapy for Helicobacter pylori eradication

12 Jan, 2023 | 13:06h | UTC

Second-line levofloxacin-based quadruple therapy versus bismuth-based quadruple therapy for Helicobacter pylori eradication and long-term changes to the gut microbiota and antibiotic resistome: a multicentre, open-label, randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


M-A | Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy effects on obesity comorbidities

12 Jan, 2023 | 13:00h | UTC

Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy effects on obesity comorbidities: A systematic review and meta-analysis – Frontiers in Surgery

 


Review | Antithrombotic therapy after bioprosthetic aortic valve replacement

12 Jan, 2023 | 12:51h | UTC

How Did We Get Here? Antithrombotic Therapy after Bioprosthetic Aortic Valve Replacement: A Review – Thrombosis and Haemostasis

 


Acute kidney injury-associated delirium: a review of clinical and pathophysiological mechanisms

12 Jan, 2023 | 12:50h | UTC

Acute kidney injury-associated delirium: a review of clinical and pathophysiological mechanisms – Critical Care

 


Review | Early diagnosis and prevention of infections in cirrhosis

12 Jan, 2023 | 12:47h | UTC

Early Diagnosis and Prevention of Infections in Cirrhosis – Seminars in Liver Disease

 


Statement | Pre-procedure and pre-admission COVID-19 testing no longer recommended for asymptomatic patients

11 Jan, 2023 | 14:36h | UTC

News Release: Pre-Procedure and Pre-Admission COVID-19 Testing No Longer Recommended for Asymptomatic Patients – Infection Control & Hospital Epidemiology

Recommendation Statement: Asymptomatic screening for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) as an infection prevention measure in healthcare facilities: Challenges and considerations – Infection Control & Hospital Epidemiology

Commentary: Infectious disease board recommends hospitals stop screening asymptomatic patients for Covid-19 – STAT

Related: Routine pre-operative Covid testing in elective surgeries: Is it worth it? – American Journal of Surgery

 


Review | Durability of vaccine-induced and natural immunity against COVID-19

11 Jan, 2023 | 14:29h | UTC

Durability of Vaccine-Induced and Natural Immunity Against COVID-19: A Narrative Review – Infectious Diseases and Therapy

 


Perspective | The limits of shared decision making

11 Jan, 2023 | 14:28h | UTC

The limits of shared decision making – BMJ Evidence-Based Medicine

 


RCT | Dupilumab in adults and adolescents with eosinophilic esophagitis

11 Jan, 2023 | 14:27h | UTC

Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Weekly Dupilumab Beneficial in Eosinophilic Esophagitis – HealthDay

 


Monkeypox (hMPXV infection): a practical review

11 Jan, 2023 | 14:25h | UTC

Monkeypox (hMPXV infection): A practical review – American Journal of Medicine

 


SR | Efficacy of presurgical interventions to promote smoking cessation

11 Jan, 2023 | 14:24h | UTC

Efficacy of Presurgical Interventions to Promote Smoking Cessation: A Systematic Review – Anesthesia & Analgesia

 


Podcast | Delirium in the hospital

11 Jan, 2023 | 14:12h | UTC

#375 Delirium in the Hospital featuring Dr. Esther Oh – The Curbsiders

 


Review | Predictors of early heart failure rehospitalization among older adults with preserved and reduced ejection fraction

11 Jan, 2023 | 13:58h | UTC

Predictors of early heart failure rehospitalization among older adults with preserved and reduced ejection fraction: A review and derivation of a conceptual model – Heart & Lung

 


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