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Internal Medicine

Syphilis in dermatology: recognition and management

31 Jan, 2023 | 14:01h | UTC

Syphilis in Dermatology: Recognition and Management – American Journal of Clinical Dermatology (if the link is paywalled, try this one in PMC)

 


M-A | Mucolytics for acute exacerbations of COPD

31 Jan, 2023 | 13:56h | UTC

Mucolytics for acute exacerbations of chronic obstructive pulmonary disease: a meta-analysis – European Respiratory Review

 


Cohort Study | Severe lymphopenia may predict worse outcomes in hospitalized patients with pneumococcal CAP

31 Jan, 2023 | 13:52h | UTC

Impact of severe lymphopenia on the early prediction of clinical outcome in hospitalized patients with pneumococcal community-acquired pneumonia – Infection (if the link is paywalled, try this one in PMC)

 


Podcast | Acute exacerbations of COPD

31 Jan, 2023 | 13:48h | UTC

#378 Acute Exacerbations of COPD (AECOPD) – The Curbsiders

 


Podcast | Hearing loss, tinnitus, and Meniere’s disease

31 Jan, 2023 | 13:46h | UTC

#379 Hearing Loss, Tinnitus, and Meniere’s Disease – The Curbsiders

 


Review | Skin infections due to Panton-Valentine Leukocidin–producing S. aureus

31 Jan, 2023 | 13:44h | UTC

Skin Infections Due to Panton-Valentine Leukocidin–Producing S. Aureus – Deutsches Ärzteblatt international

 


M-A | Vancomycin area under the curve vs. trough only guided dosing and the risk of acute kidney injury

31 Jan, 2023 | 13:32h | UTC

Vancomycin area under the curve versus trough only guided dosing and the risk of acute kidney injury: Systematic review and meta-analysis – Pharmacology

 


Accuracy of a Cystatin C–based equation to estimate GFR without the inclusion of race and sex

30 Jan, 2023 | 01:16h | UTC

Cystatin C–Based Equation to Estimate GFR without the Inclusion of Race and Sex – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Cystatin C-Based Equation Accurate for Estimating Glomerular Filtration Rate – HealthDay

 

Commentary on Twitter

 


A new study provides insights into the emotional ‘blunting’ caused by common antidepressants

30 Jan, 2023 | 01:05h | UTC

Chronic escitalopram in healthy volunteers has specific effects on reinforcement sensitivity: a double-blind, placebo-controlled semi-randomised study – Neuropsychopharmacology

News Release: Scientists explain emotional ‘blunting’ caused by common antidepressants – University of Cambridge

Commentary from the authors: Emotional ‘blunting’ and antidepressants – new research suggests why this is happening – The Conversation

 

Commentary on Twitter

 


Risk and trajectory of premature ischemic CVD in women with a history of pre-eclampsia: a nationwide register-based study

30 Jan, 2023 | 01:08h | UTC

Risk and trajectory of premature ischaemic cardiovascular disease in women with a history of pre-eclampsia: a nationwide register-based study – European Journal of Preventive Cardiology (free for a limited period)

News Release: Pre-eclampsia linked with four-fold higher risk of heart attack in decade after delivery – European Society of Cardiology

Commentaries:

Preeclampsia Increases Heart Attack, Stroke Risk for Up to 20 Years After Pregnancy – HCP Live

Preeclampsia in Pregnancy a Bad Sign for Women’s Future Heart Health – HealthDay

Related:

Cohort Study | Pre-eclampsia is associated with increased risk of premature-onset obstructive coronary artery stenosis.

Primary Care–Based Cardiovascular Disease Risk Management After Adverse Pregnancy Outcomes: a Narrative Review – Journal of General Internal Medicine

Pregnancy Complications and Risk of Cardiovascular Disease Later in Life: A Nationwide Cohort Study – Journal of the American Heart Association

AHA Scientific Statement | Adverse Pregnancy Outcomes and Cardiovascular Disease Risk

Consensus statement: Cardiovascular health after menopause transition, pregnancy disorders, and other gynecologic conditions

Cohort Study: Preeclampsia and Cardiovascular Disease

Cohort Study: Cardiovascular Disease After Hypertensive Disorders of Pregnancy Largely Explained by Conventional Cardiovascular Risk Factors

All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease

Gestational Hypertension and Future Risk of Cardiovascular Disease

Research: Conjoint Associations of Gestational Diabetes and Hypertension With Diabetes, Hypertension, and Cardiovascular Disease in Parents

 


M-A | The optimal timing and intervention to reduce mortality for necrotizing pancreatitis

30 Jan, 2023 | 00:44h | UTC

The optimal timing and intervention to reduce mortality for necrotizing pancreatitis: a systematic review and network meta-analysis – World Journal of Emergency Surgery

Related:

Long-term follow-up of a RCT | Endoscopic versus surgical step-up approach for infected necrotizing pancreatitis.

RCT: Immediate drainage did not improve outcomes compared to postponed intervention in patients with infected necrotizing pancreatitis.

An Endoscopic Transluminal Approach, Compared With Minimally Invasive Surgery, Reduces Complications and Costs for Patients With Necrotizing Pancreatitis – Gastroenterology

Research: Endoscopic or Surgical Step-up Approach for Infected Necrotising Pancreatitis

Evidence-Based Approach to the Surgical Management of Acute Pancreatitis – The Surgery Journal

Intravenous fluid therapy in patients with severe acute pancreatitis admitted to the intensive care unit: a narrative review – Intensive Care Medicine

Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis – New England Journal of Medicine (link to abstract – $ for full-text)

Acute Pancreatitis: Diagnosis and Treatment – Drugs

Revised Clinical Practice Guidelines of the Korean Pancreatobiliary Association for Acute Pancreatitis – Gut and Liver

Guidelines for the management of patients with severe acute pancreatitis, 2021 – Anaesthesia Critical Care & Pain Medicine

Evidence-Based Disposition of Acute Pancreatitis – emDocs

2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery

American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis

Pancreatitis – National Institute for Health and Care Excellence

 


SR | Perioperative clinical practice guidelines for care of older adults living with frailty

30 Jan, 2023 | 00:34h | UTC

A systematic review of perioperative clinical practice guidelines for care of older adults living with frailty – British Journal of Anaesthesia

 


Cohort Study | Exercise volume vs. intensity and the progression of coronary atherosclerosis in middle-aged and older athletes

27 Jan, 2023 | 12:29h | UTC

Exercise Volume Versus Intensity and the Progression of Coronary Atherosclerosis in Middle-Aged and Older Athletes: Findings From the MARC-2 Study – Circulation

Commentaries:

Exercise Volume vs. Intensity and Coronary Atherosclerosis Progression – American College of Cardiology

Exercise Intensity, Not Volume, Linked to Atherosclerosis Progression in Men – TCTMD

Intense exercise encourages coronary artery calcification – News Medical

 

Commentary on Twitter

 


Overuse of medications in low- and middle-income countries: a scoping review

27 Jan, 2023 | 12:31h | UTC

Overuse of medications in low- and middle-income countries: a scoping review – Bulletin of the World Health Organization

 


RCT | Higher protein dosing did not improve outcomes in critically ill patients with high nutritional risk

27 Jan, 2023 | 12:24h | UTC

The effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter (thread – click for more)

 


Perspective | Is it time to retire the diagnosis “hypertensive emergency”?

27 Jan, 2023 | 12:26h | UTC

Is it Time to Retire the Diagnosis “Hypertensive Emergency”? – Journal of the American Heart Association

 


RCT | Sodium bicarbonate over 2 years was not beneficial for kidney transplant recipients with metabolic acidosis

27 Jan, 2023 | 12:23h | UTC

Sodium bicarbonate for kidney transplant recipients with metabolic acidosis in Switzerland: a multicentre, randomised, single-blind, placebo-controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)

 


Association between healthy lifestyle and memory decline in older adults: 10 year, population based, prospective cohort study

27 Jan, 2023 | 12:21h | UTC

Association between healthy lifestyle and memory decline in older adults: 10 year, population based, prospective cohort study – The BMJ

Editorial: Healthy lifestyles for dementia prevention – The BMJ

News Release: Healthy lifestyle linked to slower memory decline in older adults – BMJ Newsroom

 


Guideline | Remission of type 2 diabetes

27 Jan, 2023 | 12:18h | UTC

Remission of Type 2 Diabetes: Diabetes Canada Clinical Practice Guidelines Expert Working Group – Canadian Journal of Diabetes

User’s Guide: Remission of Type 2 Diabetes – Canadian Journal of Diabetes

 


CT imaging of the larynx for may be a tool for the diagnosis of vocal cord dysfunction

27 Jan, 2023 | 12:13h | UTC

Computed Tomography Imaging of the Larynx for Diagnosis of Vocal Cord Dysfunction – NEJM Evidence (link to abstract – $ for full-text)

 

Commentary on Twitter

 


SR | Barriers and facilitators to deprescribing of cardiovascular medications

27 Jan, 2023 | 12:09h | UTC

Barriers and facilitators to deprescribing of cardiovascular medications: a systematic review – BMJ Open

Related:

Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease. A review by the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy – European Heart Journal – Cardiovascular Pharmacotherapy

Deprescribing in Older Adults with Cardiovascular Disease – Journal of the American College of Cardiology

Multimorbidity in Older Adults with Cardiovascular Disease – American College of Cardiology, Latest in Cardiology

 


Cohort Study | Incidence and impact of anticoagulation-associated abnormal menstrual bleeding after VTE

27 Jan, 2023 | 12:04h | UTC

Incidence and impact of anticoagulation-associated abnormal menstrual bleeding in women after venous thromboembolism – Blood

Invited Commentary: The burden of heavy menstrual bleeding – Blood

 

Commentary on Twitter

 


Review | The blood–brain barrier and optimization of antibiotics for the treatment of CNS infections in adults

27 Jan, 2023 | 11:55h | UTC

The Blood–Brain Barrier and Pharmacokinetic/Pharmacodynamic Optimization of Antibiotics for the Treatment of Central Nervous System Infections in Adults – Antibiotics

 


Cohort Study | Dietary exposure to nitrites and nitrates linked to increased risk of type 2 diabetes

26 Jan, 2023 | 12:54h | UTC

Dietary exposure to nitrites and nitrates in association with type 2 diabetes risk: Results from the NutriNet-Santé population-based cohort study – PLOS Medicine

Commentaries:

Expert reaction to study on association of nitrite additives with increased risk of type 2 diabetes – Science Media Centre

What is the association between nitrite and nitrate exposure and type 2 diabetes? – News Medical

Total Nitrite Consumption Tied to Higher Type 2 Diabetes Risk – HealthDay

 


M-A | Dose–response effects of exercise and caloric restriction on visceral adiposity in overweight and obese adults

26 Jan, 2023 | 12:52h | UTC

Dose–response effects of exercise and caloric restriction on visceral adiposity in overweight and obese adults: a systematic review and meta-analysis of randomised controlled trials – British Journal of Sports Medicine

 

Commentary on Twitter

 


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