Internal Medicine
Screening for Thyroid Cancer: USPSTF Recommendation Statement
10 May, 2017 | 18:29h | UTCScreening for Thyroid Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)
Editorial 1: The USPSTF Recommendation on Thyroid Cancer Screening: Don’t “Check Your Neck” (free)
Editorial 2: Cancer Screening, Overdiagnosis, and Regulatory Capture (free)
Editorial 3: How to Look for Thyroid Cancer (free)
Commentaries: No Symptoms, No Thyroid Screening, Says USPSTF – Medscape (free registration required) AND Don’t Screen For Thyroid Cancer, Task Force Says – NPR Health News (free) AND USPSTF Says No to Thyroid Cancer Screening – MedPage Today (free registration required)
The USPSTF recommended against screening for thyroid cancer in asymptomatic adults with “grade D” recommendation (Grade D = “The USPSTF recommends against the service. There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits”).
Intravenous fluid therapy in adults in hospital – NICE Guideline
9 May, 2017 | 20:45h | UTC
Guideline for opioid therapy and chronic noncancer pain
10 May, 2017 | 18:26h | UTCGuideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free) (RT @IrfanDhalla and @jendlake see Tweet)
Approach to the Patient with Hematochezia
9 May, 2017 | 20:43h | UTCReview: Approach to the Patient with Hematochezia – Mayo Clinic Proceedings (free) (RT @HMVJC)
Noncommunicable diseases: the slow-motion disaster
9 May, 2017 | 18:21h | UTCNoncommunicable diseases: the slow-motion disaster – World Health Organization (free)
Related WHO resources: Other dimensions of the NCD crisis: from mental health, ageing, dementia and malnutrition to deaths on the roads, violence and disability (free) AND Tools for implementing WHO PEN (Package of essential noncommunicable disease interventions) (free) AND WHO’s work on NCDs (free)
Source: Noncommunicable Diseases: A Global ‘Slow-Motion Disaster’ – Medscape (free registration required)
Type 2 diabetes in adults: management – NICE Guideline
9 May, 2017 | 20:44h | UTC
Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes
9 May, 2017 | 18:17h | UTCReview: Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes – Circulation Research (free)
Fever of unknown origin (FUO) revised
9 May, 2017 | 20:42h | UTCReview: Fever of unknown origin (FUO) revised – Wiener klinische Wochenschrift (free) (RT @HMVJC)
New Osteoporosis Guidelines from ACP
9 May, 2017 | 18:19h | UTCCommentaries: ACP Updates Guidelines on Treating Low Bone Density, Osteoporosis – Physician’s First Watch (free) AND New ACP Guidelines on the Treatment of Osteoporosis – Medscape (free registration required)
Related guideline: UK clinical guideline for the prevention and treatment of osteoporosis – Archives of Osteoporosis (free)
Reducing inappropriate prescribing easier said than done
6 May, 2017 | 20:37h | UTCReducing inappropriate prescribing easier said than done – CMAJ News (free)
Related: Canadian Deprescribing Network (CaDeN) (free)
AND CaDeN Deprescribing Guidelines and Algorithms (free) AND Deprescribing guidelines for the elderly – Ontario Pharmacy Evidence Network(free)
Series: Acute Kidney Injury in the Intensive Care Unit
6 May, 2017 | 20:32h | UTCSeries: Acute Kidney Injury in the Intensive Care Unit
Fluid management in acute kidney injury – Intensive Care Medicine (free PDF)
Renal recovery after acute kidney injury – Intensive Care Medicine (free)
Diagnostic work-up and specific causes of acute kidney injury – Intensive Care Medicine (free PDF)
Source: Critical Care Reviews Newsletter
Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images
6 May, 2017 | 20:34h | UTCSource: Management of Pulmonary Nodules Found Incidentally on Computed Tomography Scans – Journal Watch (free)
Incidental pulmonary nodules discovered outside the context of screening or cancer follow-up are increasingly common in clinical practice. The purpose of these updated recommendations is to reduce the number of unnecessary follow-up examinations while providing practical guidance on follow-up intervals for selected larger nodules.
Cardiac Patients in Trials Don’t Reflect Real-World Populations – MedPage Today
6 May, 2017 | 20:39h | UTCResearch letter: Applicability of the IMPROVE-IT Trial to Current Patients With Acute Coronary Syndrome – JAMA Internal Medicine (link to abstract – $ for full text)
Source: Cardiac Patients in Trials Don’t Reflect Real-World Populations – MedPage Today (free registration required)
Related: Exclusion of patients with concomitant chronic conditions in ongoing randomised controlled trials targeting 10 common chronic conditions and registered at ClinicalTrials.gov: a systematic review of registration details – BMJ Open (free) AND Do cancer clinical trials exaggerate the real-world benefits of drugs? – STAT News (free)
Patients in clinical trials are often younger, healthier (with less comorbidities), better plugged in to the health care system, better educated and wealthier, indicating that the external validity or generalizability of much of the current evidence to real-world settings may be relatively weak.
USPSTF recommendations: A 2017 roundup
6 May, 2017 | 20:36h | UTCUSPSTF recommendations: A 2017 roundup – Journal of Family Practice
Management of severe perioperative bleeding
6 May, 2017 | 20:31h | UTCManagement of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology (free)
Source: Critical Care Reviews Newsletter
Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017
5 May, 2017 | 20:29h | UTCCenters for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery (free) (RT @jankluytmans and @CIDRAP_ASP see Tweet)
Invited commentary: Surgical Site Infection Prevention – What We Know and What We Do Not Know – JAMA Surgery (free)
Commentary: ‘Long-Awaited’ CDC Guidelines on SSI Prevention Released – Medscape (free registration required)
Related: Global guidelines on the prevention of surgical site infection 2016 – World Health Organization (free)
8 things that excellent hospital doctors do
5 May, 2017 | 20:27h | UTCFirst opinion: 8 things that excellent hospital doctors do – STAT News (free)
Association Between Academic Medical Center Pharmaceutical Detailing Policies and Physician Prescribing
4 May, 2017 | 20:14h | UTCAssociation Between Academic Medical Center Pharmaceutical Detailing Policies and Physician Prescribing – JAMA (link to abstract – $ for full-text)
Commentaries: Doctors Prescribe More Generics When Drug Reps Are Kept At Bay – NPR (free) AND Limiting Interactions with Pharma Reps Cuts Brand Name Drug Prescriptions – Physician’s First Watch (free)
Bystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest
4 May, 2017 | 20:17h | UTCBystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (Link to abstract – $ for full-text)
Quick Take Video Summary: Bystander Efforts in Out-of-Hospital Cardiac Arrest (free)
Commentary: Bystander CPR and Defibrillation Are Associated with Better Long-Term Outcomes – Journal Watch (free)
In patients who have initially survived after out-of-hospital cardiac arrest, those who were submitted to bystander CPR and defibrillation had lower risk of brain damage, nursing home admission and death after one year when compared to patients who survived but were not submitted to bystander CPR.
Selection of patients for intra-arterial treatment for acute ischaemic stroke
4 May, 2017 | 20:18h | UTCNew decision tool: MR CLEAN-R Registry (free)
This new clinical decision tool will improve the selection of patients with acute ischemic stroke who will benefit the most from intra-arterial treatment.
Alternate-day fasting does not seem to lead to greater weight loss
3 May, 2017 | 17:26h | UTCCommentaries: Fasting Studies Clash With Our Desire To Eat What We Want, When We Want It – NPR Health News (free) AND Fasting Every Other Day Does Not Lead to Greater Weight Loss – Physician’s First Watch (free) AND Same Weight Loss With Alternate-Day Fasting vs Cutting Calories – Medscape (free registration required) AND Alternate-Day Fasting Doesn’t Lead to Speedier Weight Loss – MedPage Today (free registration required)
Randomized trial with 100 patients showed no difference in weight loss between alternate-day fasting versus calorie restriction.
Urinary catheter care: what does the evidence say?
4 May, 2017 | 20:12h | UTCUrinary catheter care: what does the evidence say? – Cochrane Library (free)
“How frequently should indwelling urinary catheters be changed? Are catheter washouts effective? Which type of catheter reduces rates of urinary tract infection?”. This post look at the evidence regarding urinary catheter care.
PCSK9 inhibitors for prevention of cardiovascular disease – Cochrane Library
3 May, 2017 | 17:28h | UTCSystematic review: PCSK9 inhibitors for prevention of cardiovascular disease – Cochrane Library (free summary – $ for full-text))
The evidence so far suggests that PCSK9 inhibitor use probably leads to little or no difference in mortality and leads to a modest absolute risk reduction (often less than 1%) in cardiovascular events in high-risk patients.
Effect of Using the HEART Score in Patients With Chest Pain in the Emergency Department
2 May, 2017 | 17:20h | UTCEffect of Using the HEART Score in Patients With Chest Pain in the Emergency Department: A Stepped-Wedge, Cluster Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
See also: HEART Score for Major Cardiac Events – MdCalc (free)
Commentaries: HEART Score for Chest Pain in ED Found to Be Safe, Cost-Effective – Physician’s First Watch (free) AND HEART Score Safely Informs Chest Pain Decisions in ED – Medscape (free registration required) AND HEART score to risk stratify patients with chest pain is safe but underutilized in the ED – ScienceDaily (free)
Prevalence of multidrug-resistant gram-negative bacteria among nursing home residents
2 May, 2017 | 17:14h | UTCSources: Study: Resistant gram-negative bacteria common in nursing homes – CIDRAP (free) (RT @IDSAInfo see Tweet) AND A quarter of nursing home residents are colonized with drug-resistant bacteria – EurekAlert (free)