Internal Medicine
BSACI guideline for the diagnosis and management of peanut and tree nut allergy
7 Jun, 2017 | 15:20h | UTCEditorial: Nut allergy guideline (free)
Commentary: First ever single guidance published for investigating and managing nut allergy – EurekAlert (free)
See also related guidelines (U.S.) and commentaries recommending early introduction of peanuts to prevent allergies in our January 6 issue, see #1 and #2.
What is the best antidote for a jellyfish sting?
7 Jun, 2017 | 15:08h | UTCCommentary: What is the best antidote for a jellyfish sting? (Clue: it’s not urine) – The Guardian (free)
Vinegar seems to be the best treatment.
Growth and Rupture Risk of Small Unruptured Intracranial Aneurysms
7 Jun, 2017 | 15:11h | UTCGrowth and Rupture Risk of Small Unruptured Intracranial Aneurysms: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Growth, rupture risk appear low for small intracranial aneurysms, review indicates – ACP Internist Weekly (free) AND How Frequently Do Small Brain Aneurysms Rupture? – MedPage Today (free registration required)
“The annualized rupture rate was 0% for aneurysms 3 mm or smaller, below 0.5% for aneurysms 5 mm or smaller, and below 1% for aneurysms 7 mm or smaller”
Home blood pressure monitors inaccurate 70 percent of the time?
7 Jun, 2017 | 15:02h | UTCCommentaries: Home blood pressure monitors inaccurate 70 percent of the time, study finds – MedicalXpress (free) AND Home blood pressure monitors may not be accurate enough – Reuters Health (free)
Small study (85 patients) suggests many of the devices are too inaccurate to be useful.
Predicting the Need for Fluid Therapy
6 Jun, 2017 | 15:00h | UTCReview: Predicting the Need for Fluid Therapy—Does Fluid Responsiveness Work? – Journal of Intensive Care (free)
Related: Fluid management series – Journal of Intensive Care (all articles are free)
Carotid Artery Stenting Versus Endarterectomy for Stroke Prevention
5 Jun, 2017 | 14:41h | UTCCarotid Artery Stenting Versus Endarterectomy for Stroke Prevention: A Meta-Analysis of Clinical Trials – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: CAS vs. CEA for Stroke Prevention – American College of Cardiology, Latest in Cardiology (free)
“CAS and CEA were associated with similar rates of a composite of periprocedural death, stroke, MI, or nonperiprocedural ipsilateral stroke. The risk of long-term overall stroke was significantly higher with CAS, and was mostly attributed to periprocedural minor stroke”.
Introducing a One-Page Adult Preventive Health Care Schedule: USPSTF Recommendations at a Glance
5 Jun, 2017 | 14:47h | UTCIntroducing a One-Page Adult Preventive Health Care Schedule: USPSTF Recommendations at a Glance – American Family Physician (free PDF)
“The popular one-page preventive health care schedule is now available with the latest USPSTF recs from 2017” (RT @AFPJournal see Tweet)
Spondyloarthritis in over 16s: diagnosis and management
5 Jun, 2017 | 14:43h | UTCSpondyloarthritis in over 16s: diagnosis and management – NICE Updated Guideline (free)
See also: 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis (free)
Iron deficiency or anemia of inflammation?
4 Jun, 2017 | 19:07h | UTC
HUS and atypical HUS
4 Jun, 2017 | 19:02h | UTCReview: HUS and atypical HUS – Blood (free)
Source: Critical Care Reviews Newsletter
Hepatotoxic risk of alcohol consumption in patients with rheumatoid arthritis taking methotrexate
4 Jun, 2017 | 19:05h | UTCCommentaries: RA, Methotrexate and Alcohol May Mix Well, to a Degree – Rheumatology Network (free) AND Moderate Alcohol Use Could Be Safe With Methotrexate for RA – Medscape (free registration required)
Autoimmune gastritis
4 Jun, 2017 | 19:06h | UTCReview: Autoimmune gastritis – Wiener Medizinische Wochenschrift (free)
Heparin-induced thrombocytopenia
4 Jun, 2017 | 19:03h | UTCReview: Heparin-induced thrombocytopenia – Blood (free)
Source: Critical Care Reviews Newsletter
Clinical updates in adult immune thrombocytopenia
4 Jun, 2017 | 19:03h | UTCClinical updates in adult immune thrombocytopenia – Blood (free)
Source: Critical Care Reviews Newsletter
Prevention of Catheter-Associated Urinary Tract Infection in Nursing Home Residents
4 Jun, 2017 | 19:01h | UTCInvited commentary: A Triumph for the Agency for Healthcare Research and Quality Safety Program for Long-term Care: Moving Beyond “Round Up the Usual Suspects”
Metformin is linked to reduced mortality in type 2 diabetes with comorbid CKD and CHF
4 Jun, 2017 | 18:43h | UTC
The diagnosis and management of patients with primary biliary cholangitis
2 Jun, 2017 | 18:42h | UTCCommentary: EASL releases updated guidelines for managing hepatitis B virus infection – Clinical Advisor (free registration required)
“Depression: let’s talk” says WHO
2 Jun, 2017 | 19:12h | UTCPress release: “Depression: let’s talk” says WHO, as depression tops list of causes of ill health – World Health Organization (free)
See also: Depression: let’s talk – WHO campaign (free) AND Depression updated factsheet (free) AND Depression and Other Common Mental Disorders: Global Health Estimates (free)
Depression is now the leading cause of ill health and disability worldwide, according to The World Health Organization.
Prophylactic Acid-Suppressive Therapy in Hospitalized Adults
2 Jun, 2017 | 18:39h | UTC
Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality
1 Jun, 2017 | 18:32h | UTCSystolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality: A Systematic Review and Network Meta-analysis – JAMA Cardiology (free) (RT @GreenlandRohan see Tweet)
Commentaries: Reducing blood pressure below recommended targets significantly reduces CVD, mortality risk – Clinical Advisor (free registration required) And New Review Supports Aggressive BP Targets – MedPage Today (free registration required)
Ideal blood pressure targets are controversial and recommendations vary across hypertension guidelines. This new meta-analysis suggests the risk of cardiovascular disease would be lowest with a systolic blood pressure between 120-124 mmHg.
Chronic constipation: Update on management
2 Jun, 2017 | 18:38h | UTCReview: Chronic constipation: Update on management – Cleveland Clinic Journal of Medicine (free)
Transient ischaemic attacks may have greater long-term impact than previously thought
2 Jun, 2017 | 18:34h | UTCTransient ischaemic attacks may have greater long-term impact than previously thought – NIHR Signal (free)
Original article: Ongoing impairments following transient ischaemic attack: retrospective cohort study – European Journal of Neurology (free)
Improving the Management of COPD in Women
1 Jun, 2017 | 18:30h | UTCReview: Improving the Management of COPD in Women – Chest (free)
Triple Therapy Versus Biologic Therapy for Active Rheumatoid Arthritis
31 May, 2017 | 16:39h | UTCTriple Therapy Versus Biologic Therapy for Active Rheumatoid Arthritis: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: In Rheumatoid Arthritis, Adding a Biologic Agent Before Trying Triple Therapy Likely Not Cost-Effective – Physician’s First Watch(free) AND Biologics before triple therapy not cost effective for rheumatoid arthritis – MedicalXpress (free) Triple Therapy More Cost-Effective Than MTX + Biologic in RA – Medscape (free registration required)
NTproBNP – A blood test threshold for diagnosing heart failure in general practice is reviewed
1 Jun, 2017 | 18:26h | UTCA blood test threshold for diagnosing heart failure in general practice is reviewed – NIHR Signal (free)
Original article: Primary care REFerral for EchocaRdiogram (REFER) in heart failure: a diagnostic accuracy study (free)
“Most accurate diagnosis for heart failure in general practice came from using NTproBNP level at a low cut-off of ≥125 pg/ml” (RT @NIHR_DCsee Tweet)


