Internal Medicine
Combination inhaler treatment in emergency departments may reduce admissions for asthma attacks
14 Jun, 2017 | 00:35h | UTCCombination inhaler treatment in emergency departments may reduce admissions for asthma attacks – NIHR Signal (free)
Original article: Combined inhaled beta-agonist and anticholinergic agents for emergency management in adults with asthma – Cochrane Library(link to abstract – $ for full-text)
A Test in Context: Fractional Flow Reserve: Accuracy, Prognostic Implications, and Limitations
14 Jun, 2017 | 00:37h | UTCA Test in Context: Fractional Flow Reserve: Accuracy, Prognostic Implications, and Limitations – Journal of The American College of Cardiology(link to abstract – $ for full-text)
10 key points to remember: FFR: Accuracy, Prognostic Implications, and Limitations – American College of Cardiology, Latest in Cardiology (free)
Guidelines for the Management of Hypertension
13 Jun, 2017 | 20:03h | UTC
Drugs may help people pass larger kidney stones
13 Jun, 2017 | 20:00h | UTCDrugs may help people pass larger kidney stones – NIHR Signal (free)
Original article: Alpha blockers for treatment of ureteric stones: systematic review and meta-analysis – The BMJ (free)
Related meta-analysis: Effect of Tamsulosin on Stone Passage for Ureteral Stones: A Systematic Review and Meta-analysis – Annals of Emergency Medicine (free)
Is the finger-stick blood test necessary for type 2 diabetes treatment?
12 Jun, 2017 | 19:58h | UTCEditorial: The Need to Test Strategies Based on Common Sense (free)
The JAMA Network – For the Media: Home Monitoring of Blood Sugar Did Not Improve Glycemic Control After 1 Year (free)
Commentary: Is the finger-stick blood test necessary for type 2 diabetes treatment? – University of North Carolina Health Care, via EurekAlert(free)
Related: Self-Monitoring of Blood Glucose – Canadian Agency for Drugs and Technologies in Health (free)
“Another RCT showing no benefit for Glucose Self-monitoring in Non–Insulin-Treated Patients with Type 2 Diabetes” (RT @PaulGlasziou see Tweet)
‘How long have I got?’: Why many cancer patients don’t have answers
12 Jun, 2017 | 19:55h | UTC‘How long have I got?’: Why many cancer patients don’t have answers – USA Today (free)
Related: Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update(free)
See more on Standardized Criteria for Palliative Care Consultation in our April 24 issue, see #8
“ASCO now recommends that everyone with advanced cancer receive palliative care within eight weeks of diagnosis.” (RT @cancerassassin1 see Tweet)
Prevention of acute kidney injury and protection of renal function in the intensive care unit
12 Jun, 2017 | 19:57h | UTCSource: Critical Care Reviews Newsletter
Working while sick
12 Jun, 2017 | 19:50h | UTCWorking with influenza-like illness: Presenteeism among US health care personnel during the 2014-2015 influenza season – American Journal of Infection Control (link to abstract – $ for full-text)
Commentaries: Working while sick – ACP Internist (free) AND Health worker survey reveals many work during flu illness – CIDRAP (free)
Over 40% of surveyed health care personnel worked with self-reported influenza-like illness. “To reduce levels of health-worker–associated flu transmission, the researchers said that misconceptions about working while sick and sick leave policies both need to be addressed” (from CIDRAP)
Lower Risk of Heart Failure and Death in Patients Initiated on SGLT-2 Inhibitors?
12 Jun, 2017 | 19:52h | UTCCommentaries: Risk of HF and Death in Patients on SGLT-2 Inhibitors – American College of Cardiology, Latest in Cardiology (free) AND SGLT2 inhibitors may have class effect for reduction of cardiac risk – ACP Diabetes Monthly (free)
Observational data suggests these class of drugs may be associated with lower risk of heart failure and deaths compared to other drugs.
Canagliflozin will receive new boxed warning about amputation risks
12 Jun, 2017 | 19:51h | UTCCanagliflozin will receive new boxed warning about amputation risks – ACP Internist (free)
FDA Drug Safety Communication: FDA confirms increased risk of leg and foot amputations with the diabetes medicine canagliflozin (Invokana, Invokamet, Invokamet XR) (free)
Gastroesophageal Reflux Disease Guideline
12 Jun, 2017 | 19:47h | UTC
Prevention and Treatment of Glucocorticoid-Induced Osteoporosis
9 Jun, 2017 | 16:04h | UTCCommentary: ACR Releases Guideline on prevention & treatment of glucocorticoid-induced osteoporosis – American College of Rheumatology, via EurekAlert (free)
Risk of Diabetic Ketoacidosis after Initiation of an SGLT2 Inhibitor
9 Jun, 2017 | 16:02h | UTCCommentaries: Study Warns of Diabetic Ketoacidosis With SGLT2 Inhibitors in T2D – MedPage Today (free registration required) AND SGLT2 Inhibitors Double the Risk for Diabetic Ketoacidosis – Medscape (free registration required) AND New class of type 2 diabetes drug associated with rare, life-threatening outcome – Brigham and Women’s Hospital, Via EurekAlert (free)
Related: SGLT2 inhibitors and diabetic ketoacidosis: data from the FDA Adverse Event Reporting System – Diabetologia (link to abstract – $ for full-text)
Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline
8 Jun, 2017 | 15:58h | UTCEditorial: Alcohol consumption and brain health (free)
Commentaries: Even moderate drinking linked to a decline in brain health, finds study – Oxford’s Department of Psychiatry (free) AND Moderate drinking may alter brain, study says – CNN (free) AND Even moderate drinking may speed brain decline – STAT News (free) AND Even moderate drinking linked to changes in brain structure, study finds – Reuters (free)
Serum uric acid levels and multiple health outcomes
8 Jun, 2017 | 15:57h | UTCObservational studies suggest that high serum uric acid levels are associated with multiple health outcomes, including cardiovascular and metabolic diseases. This review findings suggest there is a clear association only for gout and nephrolithiasis.
Practice Guidelines for Preoperative Fasting
9 Jun, 2017 | 16:03h | UTCPractice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration – Anesthesiology, via Medscape (free registration required)
Handshake-free zones to prevent infections?
8 Jun, 2017 | 15:51h | UTCHandshake-free zone in a neonatal intensive care unit: Initial feasibility study – American Journal of Infectious Control (link to abstract – $ for full-text)
Commentaries: Hospitals Could One Day Be Handshake-Free Zones To Prevent The Spread Of Disease – WBGH News (free) AND Handshake-Free Zone: Stopping the Spread of Germs in the Hospital – Medscape (free registration required) AND Handshake-Free Zones Target Spread Of Germs In The Hospital – NPR Health News (free)
Management of polypharmacy
8 Jun, 2017 | 15:52h | UTCCurrent and future perspectives on the management of polypharmacy – BMC Family Practice (free) (RT @Azeem_Majeed see Tweet)
Can Personalized Care Planning Improve Primary Care?
8 Jun, 2017 | 15:45h | UTCViewpoint: Can Personalized Care Planning Improve Primary Care? – JAMA (free)
Related: Multimorbidity: clinical assessment and management – NICE Guideline (free)
See more on caring for people with Complex Needs in our April 24th issue (see #4),
Pharmacologic Management of Newly Detected Atrial Fibrillation
7 Jun, 2017 | 15:25h | UTCKey Recommendations: Pharmacologic Management of Newly Detected Atrial Fibrillation (free)
Short-term catheterisation: considerations for best practice
8 Jun, 2017 | 15:42h | UTC
Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (again)
7 Jun, 2017 | 15:21h | UTCAntibiotics Versus Surgical Therapy for Uncomplicated Appendicitis: Systematic Review and Meta-analysis of Controlled Trials – Annals of Surgery (link to abstract – $ for full-text)
Commentary: Antibiotics Versus Surgery: Equally Effective in Treating Appendicitis? – Medscape (free registration required)
This meta-analysis and the author’s conclusions do not favor antibiotics alone for the treatment of uncomplicated appendicitis, contradiction the results of other recent meta-analysis, as well as a recent guideline on the subject, suggesting antibiotics might be an option in selected cases.
Inflammatory bowel disease: Five things physicians and patients should question
7 Jun, 2017 | 15:19h | UTC
Simplified diagnostic management of suspected pulmonary embolism
7 Jun, 2017 | 15:12h | UTCSimplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study – The Lancet(link to abstract – $ for full-text)
Commentaries: Simplified Diagnosis of Acute PE: The YEARS Study – American College of Cardiology, Latest in Cardiology (free) AND A Simple, Safe Approach to Decrease Use of CT for Pulmonary Embolism – Journal Watch (free)
Association Between Cirrhosis and Stroke
7 Jun, 2017 | 15:18h | UTCAssociation Between Cirrhosis and Stroke in a Nationally Representative Cohort – JAMA Neurology (free)
Commentary: Cirrhosis Tied to Stroke Risk- Physician’s First Watch (free)
Patients with cirrhosis seem to have a higher risk of stroke, particularly hemorrhagic stroke.


