Internal Medicine
Screening strategies for atrial fibrillation: a systematic review and cost-effectiveness analysis
23 Jul, 2017 | 13:22h | UTCSource: ACP Journal Wise ($)
“A national screening programme for atrial fibrillation is likely to represent a cost-effective use of resources, with systematic opportunistic screening more likely to be cost-effective than systematic population screening”
Workplace Factors Associated With Burnout of Family Physicians
22 Jul, 2017 | 21:47h | UTCWorkplace Factors Associated With Burnout of Family Physicians – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Workplace Factors Contribute to Burnout in Family Physicians – Medscape (free registration required)
Related: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free)
Vitamin D supplements may reduce the chance of developing a chest infection
22 Jul, 2017 | 21:31h | UTCVitamin D supplements may reduce the chance of developing a chest infection – NIHR Signal (free)
Original article: Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data – The BMJ (free)
“Daily or weekly vitamin D supplements reduced chest infections, but one-off monthly dosing gave no benefit”. (RT @NIHR_DC see Tweet)
A focus on treating fever does not improve survival in sepsis
22 Jul, 2017 | 21:10h | UTCA focus on treating fever does not improve survival in sepsis – NIHR Signal (free)
Original article: Antipyretic Therapy in Critically Ill Septic Patients: A Systematic Review and Meta-Analysis (free)
Effectiveness of Pharmacist Intervention to Reduce Medication Errors and Health-Care Resources Utilization After Transitions of Care
22 Jul, 2017 | 20:16h | UTCEffectiveness of Pharmacist Intervention to Reduce Medication Errors and Health-Care Resources Utilization After Transitions of Care: A Meta-analysis of Randomized Controlled Trials – Journal of Patient Safety (link to abstract – $ for full-text)
Source: Hospital Medicine Virtual Journal Club (free resource to find articles of interest)
Pharmacist transition of care intervention seems to be an effective strategy to reduce medication errors after hospital discharge and to reduce subsequent emergency room visits.
Studies Compare Types of Insulin for Reducing Episodes of Low Blood Sugar for Patients with Type 1 or 2 Diabetes
22 Jul, 2017 | 21:21h | UTCStudies Compare Types of Insulin for Reducing Episodes of Low Blood Sugar for Patients with Type 1 or 2 Diabetes – The JAMA Network (free commentary)
Original article 1: Effect of Insulin Degludec vs Insulin Glargine U100 on Hypoglycemia in Patients With Type 1 Diabetes: The SWITCH 1 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Original article 2: Effect of Insulin Degludec vs Insulin Glargine U100 on Hypoglycemia in Patients With Type 2 Diabetes: The SWITCH 2 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Lower rates of hypoglycemia in patients treated with insulin degludec – 2 Minute Medicine (free) AND Insulin Degludec Tied to Fewer Hypoglycemic Episodes Than Insulin Glargine – Physician’s First Watch (free)
An evidence-based, point-of-care tool to guide completion of asthma action plans in practice
22 Jul, 2017 | 21:03h | UTCRelated: Asthma self-management programmes can reduce unscheduled care – NIHR Signal (free) AND Original article: Systematic meta-review of supported self-management for asthma: a healthcare perspective – BMC Medicine (free)
Source: ACP Journal Wise ($ resource to find articles of interest)
“Researchers create practical algorithm for completing asthma action plans” (RT @PCRSUK see Tweet)
Simultaneous Antidepressant and Benzodiazepine New Use and Subsequent Long-term Benzodiazepine Use in Adults With Depression
22 Jul, 2017 | 19:19h | UTCSimultaneous Antidepressant and Benzodiazepine New Use and Subsequent Long-term Benzodiazepine Use in Adults With Depression, United States, 2001-2014 – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Benzodiazepines With Antidepressants May Spark Long-term Use – Medscape (free registration required) AND Antidepressants plus benzos: Is it worth the risk? – Pharmacy News (free)
In this large cohort, patients who were treated with benzodiazepine associated with antidepressants in the beginning of the treatment for depression didn’t seem to have a clinical benefit, and 12.3% of patients who began treatment with both agents had long-term (6-month) benzodiazepine use. Due to the observational nature of this study, it may be that these patients had more severe depression, but caution is advised nonetheless.
Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons
22 Jul, 2017 | 15:32h | UTCAssociation Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons – JAMA (link to abstract – $ for full-text)
Commentaries: Elevated Brain Amyloid Linked to Later Cognitive Decline – Medscape (free registration required) AND Amyloid Plaque and Cognitive Decline – Diagnostic Imaging (free) More Data Suggests Brain Amyloid Buildup Leads to Cognitive Decline – MedPage Today (free registration required) AND Elevated amyloid proves a warning sign of cognitive decline to come – Health Imaging (free) AND Study reveals early indication of Alzheimer’s in adults with normal cognition – News Medical (free)
Review: How I treat recurrent venous thromboembolism in patients receiving anticoagulant therapy
22 Jul, 2017 | 15:59h | UTCReview: How I treat recurrent venous thromboembolism in patients receiving anticoagulant therapy – Blood (free)
Prognostic Implications of Moderate Aortic Stenosis in Patients With Left Ventricular Systolic Dysfunction
22 Jul, 2017 | 15:50h | UTCPrognostic Implications of Moderate Aortic Stenosis in Patients With Left Ventricular Systolic Dysfunction – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Moderate Aortic Stenosis and LV Systolic Dysfunction – American College of Cardiology, Latest in Cardiology (free) AND High Risk of Clinical Events With Moderate Aortic Stenosis Plus LVSD – Medscape (free registration required)
In this observational study, patients with concomitant moderate aortic stenosis and left ventricular dysfunction were at high risk for clinical events and death.
More Millennials Are Having Strokes
22 Jul, 2017 | 14:54h | UTCPrevalence of Cardiovascular Risk Factors and Strokes in Younger Adults – JAMA Neurology (link to abstract – $ for full-text)
Commentaries: More Millennials Are Having Strokes – Scientific American (free) AND Ischemic stroke hospitalizations among younger adults increased 30% or more in recent years – Cardiovascular Business (free) AND Higher incidence of stroke and greater prevalence of stroke risk factors in younger adults over the last decade – 2 Minute Medicine (free) Is Stroke Trending Younger? – MedPage Today (free registration required) AND More Data Suggest Stroke Rates Rising in Younger Adults – Medscape (free registration required)
Short review: Subarachnoid Hemorrhage
21 Jul, 2017 | 18:27h | UTCShort review: Subarachnoid Hemorrhage – NEJM Resident 360 (free)
Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update
22 Jul, 2017 | 14:08h | UTCVenous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update. Comparative Effectiveness Review – Agency for Healthcare Research and Quality (free report and summary)
See also: Executive summary (free PDF)
Source: ACP Journal Wise ($ resource to find articles of interest)
Comprehensive review on the evidence regarding thromboembolism prophylaxis in major orthopedic surgery.
Approach to cytomegalovirus infections in patients with ulcerative colitis
21 Jul, 2017 | 18:18h | UTCReview: Approach to cytomegalovirus infections in patients with ulcerative colitis – Korean Journal of Internal Medicine (free)
Practical management of peripartum cardiomyopathy
21 Jul, 2017 | 18:16h | UTCReview: Practical management of peripartum cardiomyopathy – Korean Journal of Internal Medicine (free)
Diabetic cardiomyopathy: where we are and where we are going
21 Jul, 2017 | 18:17h | UTCReview: Diabetic cardiomyopathy: where we are and where we are going – Korean Journal of Internal Medicine (free)
Treatment of connective tissue disease-associated interstitial lung disease
21 Jul, 2017 | 18:14h | UTC
Treatment Challenges of Group A Beta-hemolytic Streptococcal Pharyngo-Tonsillitis
21 Jul, 2017 | 18:09h | UTCClinical Review: Treatment Challenges of Group A Beta-hemolytic Streptococcal Pharyngo-Tonsillitis – International Archives of Otorhinolaryngology (free)
Review: Optimizing diagnostic testing for venous thromboembolism
21 Jul, 2017 | 18:04h | UTCClinical Review: Optimizing diagnostic testing for venous thromboembolism – Cleveland Clinic Journal of Medicine (free)
Surgical site infections after cesarean delivery: epidemiology, prevention and treatment
21 Jul, 2017 | 17:58h | UTC
Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin
21 Jul, 2017 | 17:51h | UTCAntiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis – Stroke (link to abstract – $ for full-text)
Commentary: Adjusting Antiplatelet Regimen Could Decrease Risk For Stroke Patients on Aspirin Monotherapy – American College of Cardiology, Latest in Cardiology (free)
Meta-analysis of cohort studies: in patients who experienced an ischemic stroke or transient ischemic attack while on aspirin monotherapy, the addition of or a switch to another antiplatelet agent, versus aspirin monotherapy, was associated with a 32 percent reduction in the risk of major adverse cardiovascular events (HR 0.68; 0.54–0.85) and 30 percent reduction in recurrent strokes (HR, 0.70; 0.54–0.92). Additional randomized trials would better clarify the best antiplatet regimen for these patients.
NICE Guideline: Parkinson’s disease in adults
21 Jul, 2017 | 17:52h | UTCParkinson’s disease in adults – National Institute for Health and Care Excellence (NICE) Guideline (free)
Dementia prevention, intervention, and care
21 Jul, 2017 | 17:40h | UTCReport: Dementia prevention, intervention, and care – The Lancet (free registration required)
Commentaries: Experts: 1 in 3 cases of dementia preventable, nonmedical therapies ideal for dementia – University of Southern California, via EurekAlert (free) AND One Third of Dementia May Be Preventable With Lifestyle Change – Medscape (free registration required) AND Over a Third of Dementia Cases Tied to Modifiable Risk Factors – Physician’s First Watch (free) AND Living healthily, learning more could cut dementia cases by a third – Reuters (free) AND Lifestyle changes could prevent a third of dementia cases, report suggests – The Guardian (free)
The Aging Physician and the Medical Profession: A Review
21 Jul, 2017 | 00:25h | UTCThe Aging Physician and the Medical Profession: A Review – JAMA Sugery (free) (RT @EricTopol see Tweet)