Internal Medicine | Page 456 of 487 | Links Medicus Content Curation & Alerts in Medicine

Iron chelation with oral Deferasirox (instead of injected deferoxamine) may offer an important treatment option for people with thalassaemia and secondary iron overload.

Study: Community-acquired Pneumonia Visualized on Computed Tomography but Not Chest X-Ray

29 Aug, 2017 | 14:54h | UTC

Community-acquired Pneumonia Visualized on Computed Tomography but Not Chest X-Ray: Pathogens, Severity, and Clinical Outcomes – Chest (link to abstract – $ for full-text)

Source: Hospital Medicine Virtual Journal Club (free resource to find articles of interest)

“Adults hospitalized with CAP who had radiologic evidence of pneumonia on CT but not concurrent CXR had similar pathogens, disease severity, and outcomes compared with patients who had signs of pneumonia on CXR”.

Guideline: Osteoarthritis of the Knee Clical Care Standard

29 Aug, 2017 | 15:00h | UTC

Osteoarthritis of the Knee Clical Care Standard – Australian Commission on Safety and Quality in Health Care (PDF Guideline and other resources)

Source: Research Review Australia (free resource to find articles of interest)

Review: DRESS: What does the emergency physician need to know?

29 Aug, 2017 | 14:54h | UTC

DRESS: What does the emergency physician need to know? – emDocs (free)

#ESCCongress – 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation

27 Aug, 2017 | 20:11h | UTC

2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC) (free) (RT @rafavidalperez see Tweet)

Commentary: ESC Updates Guidelines for Treating STEMI Patients – TCTMD (free)

See also: #ESCCongress Slides (free PPT file)

#ESCCongress – 2017 ESC/EACTS Guidelines for the management of valvular heart disease

27 Aug, 2017 | 20:12h | UTC

2017 ESC/EACTS Guidelines for the management of valvular heart disease (free) (RT @rafavidalperez see Tweet)

Commentary: European Societies Issue New Valvular Heart Disease Guidelines, With Important Shifts – TCTMD (free)

See also: #ESCCongress Slides (free PPT file)

#ESCCongress – Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation

27 Aug, 2017 | 20:07h | UTC

Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation – New England Journal of Medicine (free)

Commentaries: Randomized Evaluation of Dual Antithrombotic Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With Nonvalvular Atrial Fibrillation Undergoing Percutaneous Coronary Intervention – RE-DUAL PCI – American College of Cardiology, Latest in Cardiology (free) Dual Antithrombotic Therapy Is Safe for Patients with AF and a New Stent – Physician’s First Watch (free) AND When two is better than three: Dual antithrombotic therapy cuts bleeding risk – Brigham and Women’s Hospital, via ScienceDaily (free)

“In summary, several lines of evidence now suggest that it is safe to treat atrial fibrillation patients who undergo coronary revascularization with anticoagulation (warfarin studied in WOEST, rivaroxaban studied in PIONEER AF-PCI, dabigatran studied in RE-DUAL PCI) and clopidogrel monotherapy” (from American College of Cardiology, Latest in Cardiology).

#ESCCongress – 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases

27 Aug, 2017 | 20:10h | UTC

2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries (free) (RT @rafavidalperez see Tweet)

See also: #ESCCongress Slides (free PPT file)

#ESCCongress – 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease

27 Aug, 2017 | 20:09h | UTC

2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS (free) (RT @rafavidalperez see Tweet)

See also: #ESCCongress Slides (free PPT file)

#ESCCongress – Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease

27 Aug, 2017 | 20:08h | UTC

Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease – New England Journal of Medicine (free)

Editorial by Dr. Eugene Braunwald: An Important Step for Thrombocardiology (free)

Commentaries: Cardiovascular Outcomes for People Using Anticoagulation Strategies – COMPASS – American College of Cardiology, Latest in Cardiology (free) AND COMPASS: Does Rivaroxaban Plus Aspirin Improve CV Outcomes in Patients With Stable Atherosclerotic Vascular Disease or PAD? – ACC News Story (free) AND Rivaroxaban, Aspirin, or Both in Stable Coronary Disease – Physician’s First Watch (free)

The primary outcome (composite of cardiovascular death, stroke, or myocardial infarction) occurred in fewer patients in the rivaroxaban-plus-aspirin group than in the aspirin-alone group (4.1% vs. 5.4% / Absolute risk difference = 1.3% / NNT = 76), but major bleeding events occurred in more patients in the rivaroxaban-plus-aspirin group (3.1% vs. 1.9% / Absolute risk difference = 1.2 / NNH = 83).

Review: Malignant Otitis Externa: Diagnosis and Treatment

26 Aug, 2017 | 20:30h | UTC

Malignant Otitis Externa: Diagnosis and Treatment – emDocs (free)

#ESCCongress – Incidence of Previously Undiagnosed Atrial Fibrillation Using Insertable Cardiac Monitors in a High-Risk Population

27 Aug, 2017 | 20:03h | UTC

Incidence of Previously Undiagnosed Atrial Fibrillation Using Insertable Cardiac Monitors in a High-Risk Population: The REVEAL AF Study (free)

Commentaries: What Do Implanted Cardiac Monitors Reveal About Atrial Fibrillation? – JAMA Cardiology (free) AND REVEAL AF: Incidence of AFib Could Be Substantial in Older Patients With Stroke Risk Factors – American College of Cardiology, Latest in Cardiology (free) AND Detection of Undiagnosed AF Using Insertable Cardiac Monitors – American College of Cardiology, Latest in Cardiology (free)

Implanted Cardiac Monitors showed the incidence of intermittent atrial fibrillation is extremely common among older individuals with stroke risk factors, but the clinical significance of these findings (do they need to be anticoagulated??) remains to be determined by further trials.

“Previous long-term monitoring studies have suggested that patients with short episodes of subclinical AF have a lower risk of stroke compared with traditional clinical AF, which raises important questions about the risk-benefit ratio of anticoagulation in this setting” (from Latest in Cardiology).

#ESCCongress – Catheter ablation improves outcomes in patients with heart failure and atrial fibrillation

27 Aug, 2017 | 20:03h | UTC

Catheter ablation improves outcomes in patients with heart failure and atrial fibrillation (CASTLE-AF) (free)

Commentary: CASTLE-AF: Catheter Ablation vs. Conventional Therapy For Patients With AFib and LV Dysfunction – American College of Cardiology, Latest in Cardiology (free)

The study has not been published yet, but the results suggest that patients with symptomatic paroxysmal or persistent AF and heart failure with ejection fraction less than 35% may have a better outcome with catheter ablation.