Internal Medicine | Page 455 of 487 | Links Medicus Content Curation & Alerts in Medicine

Study: effects of probiotic and peanut oral immunotherapy for peanut allergy

31 Aug, 2017 | 15:53h | UTC

Long-term clinical and immunological effects of probiotic and peanut oral immunotherapy after treatment cessation: 4-year follow-up of a randomised, double-blind, placebo-controlled trial – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)

Commentaries: Benefits of Immunotherapy-Probiotic Combo for Peanut Allergy Sustained at 4 Years – Physician’s First Watch (free) AND Peanut Allergy: Is Oral Immunotherapy With Probiotic a Cure? – Medscape (free registration required) AND Peanut Allergy Tx Efficacy Examined in 4-Year Follow-Up Study – MPR (free)

Meta-analysis: Association of Sleep-Disordered Breathing With Cognitive Function and Risk of Cognitive Impairment

30 Aug, 2017 | 20:37h | UTC

Association of Sleep-Disordered Breathing With Cognitive Function and Risk of Cognitive Impairment: A Systematic Review Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)

Commentaries: Breathing Disorders During Sleep Tied to Cognitive Issues – MedPage Today (free registration required) AND Sleep-Disordered Breathing Raises Risk for Cognitive Decline – Medscape (free registration required)

This meta-analysis of observational studies suggests a possible association. Further studies are needed to examine whether the treatment of this condition can help in the prevention of dementia and in improvement of cognition.

Study: Resistance training may prevent obese older people becoming frail when losing weight

30 Aug, 2017 | 19:12h | UTC

Resistance training may prevent obese older people becoming frail when losing weight – NIHR Signal (free)

Original article: Aerobic or Resistance Exercise, or Both, in Dieting Obese Older Adults – New England Journal of Medicine (link to abstract – $ for full-text) AND Video Summary: Exercise and Dieting in Obese Older Adults (free)

Study: Medical Students Fall Short on Blood Pressure Check Challenge

30 Aug, 2017 | 20:20h | UTC

Medical News & Perspectives: Medical Students Fall Short on Blood Pressure Check Challenge – JAMA (free)

Original Article: Medical students and measuring blood pressure: Results from the American Medical Association Blood Pressure Check Challenge – The Journal of Clinical Hypertension (free)

“Only 1 out of 159 medical students correctly performed all 11 elements in a BP check challenge w simulated patients” (RT @JAMA_current see Tweet)

#ESCCongress – Observational Study: Clopidogrel or ticagrelor in acute coronary syndrome patients treated with newer-generation drug-eluting stents

30 Aug, 2017 | 19:01h | UTC

#ESCCongress – Clopidogrel or ticagrelor in acute coronary syndrome patients treated with newer-generation drug-eluting stents: CHANGE DAPT – EuroIntervention (link to abstract – $ for full-text)

Commentaries: Rethinking dual antiplatelet guidelines in acute coronary syndrome? (CHANGE-DAPT) – ESC Press Releases (free) AND Ticagrelor for DAPT Again Questioned in Current Era of PCI for ACS: CHANGE DAPT – Medscape (free registration required)

CHANGE DAPT: Study Contests Benefit of Ticagrelor Over Clopidogrel After PCI in ACS – TCTMD (free)

Study: Lack of REM sleep may lead to higher risk for dementia

30 Aug, 2017 | 19:08h | UTC

Sleep architecture and the risk of incident dementia in the community – Neurology (link to abstract – $ for full-text)

Commentaries: Lack of REM sleep may lead to higher risk for dementia – Boston University School of Medicine, via EurekAlert (free) AND Less REM Sleep May Significantly Boost Dementia Risk – Medscape (free registration required) AND Dreaming may keep dementia at bay – Medical News Today (free) AND Lack of REM sleep tied to increased risk of dementia – Reuters (free)

#ESCCongress – Cohort Study: Fruit, vegetable, and legume intake, and cardiovascular disease and deaths

30 Aug, 2017 | 18:32h | UTC

#ESCCongress – Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study – The Lancet (link to abstract – $ for full-text)

Commentaries: Reassessing the benefits of plant-based eating (PURE) – ESC Press Release (free) Fruit, Vegetable, Legume Intake and CVD Events – American College of Cardiology, Latest in Cardiology (free) AND Life-saving fruit and vegetable diet need only be three portions – study – The Guardian (free) AND Less Is More? Health Benefits of Fruits, Vegetables, and Legumes Seen at Lower Intake Levels – TCTMD (free)

#ESCCongress – Study confirms safety of rapid algorithm to rule-out and rule-in myocardial infarction

30 Aug, 2017 | 18:31h | UTC

Study confirms safety of rapid algorithm to rule-out and rule-in myocardial infarction – ESC Press Release (free) (the results have not been published yet)

Commentary: ESC Rapid Rule-In, Rule-Out Algorithm for NSTEMI Safe, Accurate – Medscape (free registration required)

#ESCCongress – Cohort Study: Associations of fats and carbohydrate intake with cardiovascular disease and mortality

30 Aug, 2017 | 18:33h | UTC

#ESCCongress – Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study – The Lancet (link to abstract – $ for full-text)

Commentaries: Revisiting dietary fat guidelines? (PURE) – ESC Press Release (free) AND PURE Investigators: Rethink Diet Guidance to Plug More Fats, Fewer Carbs – TCTMD (free) AND International study shows moderate consumption of fats and carbohydrates best for health – McMaster University, via EurekAlert (free) AND PURE: Findings Could Have Implications For Global Dietary Guidelines – ACC News Story (free) AND Huge Diet Study Questions Conventional Wisdom About Carbs And Fats – Cardiobrief (free)

#ESCCongress – Study: Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease

30 Aug, 2017 | 18:29h | UTC

Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease – New England Journal of Medicine (free)

Commentaries: Anacetrapib REVEALs ‘Modest’ Effect on Cardiovascular Outcomes – Medscape (free registration required) AND Anacetrapib Finds (Modest) Success Where All Other CETP Inhibitors Failed – TCTMD (free) AND REVEAL Revealed: A Slightly Positive CETP Inhibitor Trial – Cardiobrief (free)

Interesting new drug, but with modest benefits. During the median follow-up period of 4.1 years, the primary outcome occurred in fewer patients in the anacetrapib group than in the placebo group (10.8% vs. 11.8% / absolute risk difference = 1%, meaning 100 patients would have to be treated for 4.1 years to benefit 1 patient)