Internal Medicine
Meta-analysis: Low alcohol consumption and pregnancy and childhood outcomes
20 Sep, 2017 | 22:25h | UTCCommentaries: No change to alcohol guidelines for pregnancy – NHS Choices (free) Health risks of light drinking in pregnancy confirms that abstention is the safest approach – The Conversation (free)
Cohort Study: Metabolically Healthy Obese and Incident Cardiovascular Disease Events
20 Sep, 2017 | 22:23h | UTCMetabolically Healthy Obese and Incident Cardiovascular Disease Events Among 3.5 Million Men and Women – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: New evidence shows that healthy obesity is a myth – The Conversation (free) AND Study shows so-called ‘healthy obesity’ is harmful to cardiovascular heath – Medical News Today (free) AND Obesity, even without other risk factors, leads to higher rate of cardiovascular disease – STAT (free) AND Another Study Challenges Notion of ‘Healthy Obese’ – TCTMD (free)
See related article and commentaries in our August 21st issue (see #1)
Effects of Intensive Systolic Blood Pressure Control on Kidney and Cardiovascular Outcomes in Persons Without Kidney Disease
20 Sep, 2017 | 21:12h | UTCCommentary: Cardiovascular benefits of intensive systolic blood pressure control may outweigh risks of chronic kidney disease events – 2 Minute Medicine (free)
Blood pressure measures in the SPRINT trial were done in a different way than most trials. If these results are to be incorporated in clinical practice, blood pressure measurement must be done in the same way. More details in Cardiobrief: Can SPRINT Be Used To Inform Hypertension Treatment? (free)
Review: Evaluation of bleeding in patients receiving direct oral anticoagulants
20 Sep, 2017 | 21:11h | UTC
Review: Ultrasound-guided central venous catheter placement
20 Sep, 2017 | 21:07h | UTC
Review: Multiple Myeloma Emergencies
20 Sep, 2017 | 21:06h | UTCMultiple Myeloma Emergencies – emDocs (free)
Randomized Controled Trial: Efficacy of Thalidomide in Preventing Delayed Nausea and Vomiting Induced by Chemotherapy
20 Sep, 2017 | 20:55h | UTCEfficacy of Thalidomide in Preventing Delayed Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy: A Randomized, Multicenter, Double-Blind, Placebo-Controlled Phase III Trial (CLOG1302 study) – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentaries: Thalidomide Improves Prevention of Delayed Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy – PracticeUpdate (free registration required) AND Adding Thalidomide to Palonosetron, Dexamethasone Reduces CINV – Oncology Nurse Advisor (free)
Review: Diaphragm Dysfunction in Critical Illness
20 Sep, 2017 | 20:53h | UTCDiaphragm Dysfunction in Critical Illness – Chest (free PDF)
Source: Hospital Medicine Virtual Journal Club
Systematic review: Non-pharmacological self-management for people living with migraine or tension-type headache
20 Sep, 2017 | 20:54h | UTCCommentary: Non-Pharmacological Self-Management Effective for People With Migraine or Tension-Type Headache – PracticeUpdate (free registration required)
FDA recommends separating dosing of potassium-lowering drug sodium polystyrene sulfonate (Kayexalate) from all other oral drugs
20 Sep, 2017 | 20:50h | UTCFDA Drug Safety Communication: FDA recommends separating dosing of potassium-lowering drug sodium polystyrene sulfonate (Kayexalate) from all other oral drugs (free)
Commentary: Don’t Give Kayexalate With Other Oral Drugs, FDA Warns – Medscape (free registration required)
“Patients should take orally administered prescription and over-the-counter (OTC) medicines at least 3 hours before or 3 hours after sodium polystyrene sulfonate”
Retrospective Cohort: Characteristics of Diabetes of the Exocrine Pancreas
20 Sep, 2017 | 20:45h | UTCIncidence, Demographics, and Clinical Characteristics of Diabetes of the Exocrine Pancreas (Type 3c): A Retrospective Cohort Study – Diabetes Care (link to abstract – $ for full-text)
Commentary: Glycemic control poor, insulin use high in diabetes after pancreatic disease – Haelio (free registration required)
“Diabetes following pancreatic disease associated with poor glycemic control compared with T2 diabetes” (RT @kamleshkhunti see Tweet)
Review: Common Drug Side Effects and Drug-Drug Interactions in Elderly Adults in Primary Care
20 Sep, 2017 | 20:44h | UTCCommon Drug Side Effects and Drug-Drug Interactions in Elderly Adults in Primary Care – Journal of The American Geriatrics Society, via Medscape (free registration required)
Meta-analysis: efficacy of probiotics in inflammatory bowel disease
20 Sep, 2017 | 20:43h | UTCCommentary: Probiotics May Have Benefits for Ulcerative Colitis, but Not Crohn’s Disease – Medscape (free registration required)
Summaries with 10 key points to remember of the latest European Society of Cardiology Guidelines
19 Sep, 2017 | 22:32h | UTCSummaries with 10 key points to remember of the latest European Society of Cardiology Guidelines – Latest in Cardiology, American College of Cardiology
– 2017 ESC Guidelines for the Management of STEMI (free)
– 2017 ESC/EACTS Guidelines for Management of Valvular Heart Disease (free)
– 2017 ESC Guidelines for PAD Diagnosis and Treatment (free)
– 2017 ESC Focused Update on DAPT in CAD (free)
See also our sellection of the most relevant articles and commentaries from the Meeting, #ESCCongress Part I, #ESCCongress Part II and #ESCCongress Part III
Meta-Analysis: Corticosteroids in patients hospitalized with community-acquired pneumonia
19 Sep, 2017 | 22:34h | UTCCorticosteroids in patients hospitalized with community-acquired pneumonia: systematic review and individual patient data meta-analysis – Clinical Infectious Diseases (link to abstract – $ for full-text)
Related Meta-analysis: Efficacy and Safety of Adjunctive Corticosteroids Therapy for Severe Community-Acquired Pneumonia in Adults: An Updated Systematic Review and Meta-Analysis – PLOS One (free) AND Efficacy and Safety of Corticosteroids for Community-Acquired Pneumonia – Chest (free) AND Adjunctive Systemic Corticosteroids for Hospitalized Community-Acquired Pneumonia: Systematic Review and Meta-Analysis 2015 Update – Scientific Reports (free)
Guideline: Ethics and the Legalization of Physician-Assisted Suicide
19 Sep, 2017 | 22:31h | UTCCommentaries: ACP reaffirms opposition to physician-assisted suicide – ACP Internist (free) AND ACP Reaffirms Position Against Physician-Assisted Suicide – Physician’s First Watch (free)
Review: Impact of Electronic Cigarettes on the Cardiovascular System
19 Sep, 2017 | 22:29h | UTC
Guideline: Contemporary Management of Cardiogenic Shock
19 Sep, 2017 | 22:28h | UTCTop Ten Things to Know: Contemporary Management of Cardiogenic Shock (free PDF)
The Promise and Challenge of Liquid Biopsies
19 Sep, 2017 | 22:26h | UTCMedical News & Perspectives: Going With the Flow: The Promise and Challenge of Liquid Biopsies – JAMA (free)
Related: Emerging concepts in liquid biopsies – BMC Medicine (free) AND Can a ‘liquid biopsy’ detect cancer and save lives? – STAT (free)
Cancer’s Invasion Equation
19 Sep, 2017 | 22:27h | UTCCancer’s Invasion Equation – The New Yorker (free)
We can detect tumors earlier than ever before. Can we predict whether they’re going to be dangerous?
Cohort study: The cumulative burden of surviving childhood cancer
19 Sep, 2017 | 22:24h | UTCThe cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE) – The Lancet (link to abstract – $ for full-text)
Commentaries: Survivors of Childhood Cancer Face Continuing Chronic Health Conditions – Physician’s First Watch (free) AND Severe Health Problems Plague Survivors of Childhood CA – Medscape (free registration required) AND Comprehensive Study of Chronic Disease Reveals Vulnerability of Childhood Cancer Survivors – NewsWise (free)
Use of public defibrillators linked to out-of-hospital cardiac arrest survival
19 Sep, 2017 | 22:25h | UTCUse of public defibrillators linked to out-of-hospital cardiac arrest survival – NIHR Signal (free)
Original article: The Effects of Public Access Defibrillation on Survival After Out-of-Hospital Cardiac Arrest: A Systematic Review of Observational Studies – Circulation (link to abstract – $ for full-text)
“Each minute of delay to defibrillation is estimated to reduce the probability of long-term survival by 10%” (RT @NIHR_DC see Tweet)
Meta-Analysis: The Weekend Effect in Hospitalized Patients
19 Sep, 2017 | 22:21h | UTCThe Weekend Effect in Hospitalized Patients: A Meta-Analysis – Journal of Hospital Medicine (link to abstract – free full-text PDF via @unpaywall)
Commentary: Review finds evidence for weekend effect on mortality in hospitalized patients – ACP Hospitalist (free)
Related article: Weekends affect mortality risk and chance of discharge in critically ill patients: a retrospective study in the Austrian registry for intensive care – Critical Care (free) AND Commentary: “Weekend effects” in intensive care units – On Medicine (free)
Richard Lehman’s journal review, 18 September 2017
19 Sep, 2017 | 22:20h | UTCRichard Lehman’s journal review, 18 September 2017 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Viewpoint: Nutrition Counseling in Clinical Practice: How Clinicians Can Do Better
19 Sep, 2017 | 22:23h | UTCNutrition Counseling in Clinical Practice: How Clinicians Can Do Better – JAMA (free)