Internal Medicine

Antibiotic-associated diarrhea ocurred in 8.0% of the probiotic group compared to 17.7% in the control group. The number needed to treat (NNT) to prevent one case of diarrhea was 11 (95% CI 6 to 13).

Research: Receipt of Blood Transfusion From Previously Pregnant Donor Associated with Increased Risk of Death Among Male Recipients

21 Oct, 2017 | 17:33h | UTC

Association of Blood Transfusion From Female Donors With and Without a History of Pregnancy With Mortality Among Male and Female Transfusion Recipients – JAMA (link to abstract – $ for full-text)

Commentaries: Blood Boundaries: Should Transfusions Be Matched by Sex? – Scientific American (free) AND Are transfusions harmful to men if the blood comes from women who have been pregnant? – STAT (free) AND Receipt of Blood Transfusion From Previously Pregnant Donor Associated with Increased Risk of Death Among Male Recipients – The JAMA Network (free)

Review: How Low to Go With Glucose, Cholesterol, and Blood Pressure in Primary Prevention of CVD

21 Oct, 2017 | 17:28h | UTC

How Low to Go With Glucose, Cholesterol, and Blood Pressure in Primary Prevention of CVD – Journal of The American College of Cardiology (free)

Summary with 12 key points to remember: Glucose, Cholesterol, BP Targets for CVD Risk Factors – American College of Cardiology, Latest in Cardiology (free)

Research: Comparative safety of direct oral anticoagulants and warfarin in venous thromboembolism

21 Oct, 2017 | 17:30h | UTC

Comparative safety of direct oral anticoagulants and warfarin in venous thromboembolism: multicentre, population based, observational study – The BMJ (free)

Commentary: New Anticoagulants Not Linked To Excess Bleeding Rates – Cardiobrief (free)

Research: Omega-6 fatty acid biomarkers and incident type 2 diabetes

21 Oct, 2017 | 17:28h | UTC

Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39 740 adults from 20 prospective cohort studies – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentaries: Omega-6 fats may help prevent type 2 diabetes – George Institute for Global Health (free) AND Eating More Nuts Could Protect Against Type 2 Diabetes – Medscape (free registration required) AND Omega-6 could lower type 2 diabetes risk by 35 percent – Medical News Today (free)

Research: Iron absorption from oral iron supplements given on consecutive versus alternate days

17 Oct, 2017 | 19:10h | UTC

Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials – The Lancet Haematology (free)

Commentaries: Treatment of iron deficiency is getting trendy – The Lancet Haematology (free) AND Taking Iron Every Other Day Linked to Better Absorption in Iron-Deficient Women – Physician’s First Watch (free)

Guidelines Synopsis: Management of a Diabetic Foot

17 Oct, 2017 | 19:08h | UTC

Management of a Diabetic Foot – JAMA Clinical Guidelines Synopsis (free) (RT @adamcifu)

Original guideline: The management of diabetic foot: A clinical practice guideline by the Society for Vascular Surgery in collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine (free)

Research: Increasing prevalence of vascular risk factors in patients with stroke

17 Oct, 2017 | 19:06h | UTC

Increasing prevalence of vascular risk factors in patients with stroke – Neurology (link to abstract – $ for full-text)

Commentary: Health Conditions That Increase Stroke Risk Rise Across All Ages, Races – NPR (free)

“An estimated 80% of all 1st strokes are due to risk factors that can be changed,” says new study (RT @ACCmediacenter see Tweet)

Review: Management of cardiovascular diseases in patients with obesity

17 Oct, 2017 | 19:03h | UTC

Management of cardiovascular diseases in patients with obesity – Nature Reviews Cardiology (free)

Guidelines on perioperative medication in adult cardiac surgery

17 Oct, 2017 | 19:01h | UTC

2017 EACTS Guidelines on perioperative medication in adult cardiac surgery – European Journal of Cardio-Thoracic Surgery (free)

Source: Critical Care Reviews Newsletter (free)

Systematic review: Testing blood procalcitonin levels to decide when to start and stop antibiotics in adults with acute respiratory tract infections

17 Oct, 2017 | 19:00h | UTC

Testing blood procalcitonin levels to decide when to start and stop antibiotics in adults with acute respiratory tract infections – Cochrane Library (free)

Original Article: Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections – Cochrane Library (link to abstract – $ for full-text)

“the use of procalcitonin to guide initiation and duration of antibiotic treatment results in lower risks of mortality, lower antibiotic consumption, and lower risk for antibiotic-related side effects”.

Older people with acute coronary syndromes may benefit from routine invasive therapy

17 Oct, 2017 | 19:02h | UTC

Older people with acute coronary syndromes may benefit from routine invasive therapy – NIHR Signal (free)

Original article: Revascularisation compared with initial medical therapy for non-ST-elevation acute coronary syndromes in the elderly: a meta-analysis – Heart (link to abstract – $ for full-text)

Draft Recommendation Statement: Skin Cancer Prevention

17 Oct, 2017 | 18:58h | UTC

Draft Recommendation Statement: Skin Cancer Prevention: Behavioral Counseling – U.S. Preventive Services Task Force (free)

Commentary: USPSTF Draft Statement Recommends Sun-Safe Behavioral Counseling for More Fair-Skinned Youth – Physician’s First Watch (free)

Research: Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging

17 Oct, 2017 | 19:02h | UTC

Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging – Proceedings of the National Academy of Sciences (free)

Commentary: Rapid Test for Antibiotic Susceptibility – JAMA (free)

Related guideline: Healthcare Personnel Attire in Non-Operating-Room Settings – Infection Control and Hospital Epidemiology (free) AND Commentaries: Goodbye to the Doctor’s White Coat? – The New York Times (10 articles per month are free) AND New infection control recommendations could make white coats obsolete – ScienceDaily (free) AND Should Doctors Still Be Allowed to Wear White Coats? You Decide – HIV and ID Observations (free)

Expert Consensus Decision Pathway on the Management of Mitral Regurgitation

Long-term antibiotics likely to reduce risk of recurrent cellulitis

Research: Short-Course Versus Prolonged-Course Antibiotic in Adults With Enterobacteriaceae Bacteremia

Richard Lehman’s journal review – 17 October 2017

Research: Short and Long Term Complications of In Utero Exposure to Lamotrigine

Guideline: 2017 Appropriate Use Criteria for the Treatment of Patients With Severe Aortic Stenosis

Research: Patient Frailty and Morbidity After Common Ambulatory General Surgery Operations

Research: 25-Year Physical Activity Trajectories and Development of Subclinical Coronary Artery Disease

Meta-analysis: Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients