Internal Medicine
Research: Blood Pressure Status in Adult Survivors of Childhood Cancer
28 Nov, 2017 | 19:25h | UTCBlood Pressure Status in Adult Survivors of Childhood Cancer: A Report from the St. Jude Lifetime Cohort Study – Cancer Epidemiology, Biomarkers & Prevention (link to abstract – $ for full-text)
Commentaries: Adult Survivors of Childhood Cancer Are More Likely to Develop High Blood Pressure – American Association for Cancer Research (free) AND Childhood cancer survivors 70% likely to develop hypertension as adults – Cardiovascular Business (free)
Related Guideline: Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free)
Meta-Analysis: Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients
28 Nov, 2017 | 19:27h | UTCProlonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)
Source: ACP Journal Wise ($)
“Receipt of prolonged infusion of piperacillin-tazobactam was associated with reduced mortality and improved clinical cure rates across diverse cohorts of severely ill patients”.
Research: Tolerability profile of glucocorticoids use in early rheumatoid arthritis
28 Nov, 2017 | 19:26h | UTCCommentaries: Long-Term Safety of Glucocorticoids in Patients with Early Rheumatoid Arthritis – Journal Watch (free) AND Long-term Low-dose Steroids OK in Early RA – MedPage Today (free registration required)
“Long-Term Safety of Glucocorticoids in Early Rheumatoid Arthritis. Stopping steroids completely is difficult in patients whose disease flares with tapering, but low-dose levels are relatively safe” (RT @JWatch see Tweet)
Research: Thyroid Function and the Risk of Atherosclerotic Cardiovascular Morbidity and Mortality
26 Nov, 2017 | 00:30h | UTCCommentaries: Higher thyroid hormone levels associated with artery disease and death – AHA/ASA Newsroom (free) AND High Thyroid-Hormone Levels Linked to Increased CVD Mortality – Medscape (free registration required)
Research: Predictors of pneumonia in lower respiratory tract infections
26 Nov, 2017 | 00:26h | UTCCommentaries: Four clinical signs can improve GP pneumonia diagnosis, finds study – Pulse (free) AND Four simple tests could help GPs spot pneumonia and reduce unnecessary antibiotics – European Lung Fundation, via EurekAlert (free)
Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
26 Nov, 2017 | 00:29h | UTCCommentary: Updated International Guidelines for Ventilation During CPR – Journal Watch (free)
Meta-Analysis: Inappropriate Management of Patients With Asymptomatic Bacteriuria
26 Nov, 2017 | 00:28h | UTC“OFID: Despite guidelines, continued overtreatment of patients with positive urine cultures but no symptoms” (RT @IDSAInfo see Tweet)
Meta-analysis: High-flow nasal cannula oxygen therapy
26 Nov, 2017 | 00:20h | UTC
Meta-analysis Comparing Treatments for Acute Renal Colic
26 Nov, 2017 | 00:24h | UTCSystematic Review and Meta-analysis Comparing the Efficacy of Nonsteroidal Anti-inflammatory Drugs, Opioids, and Paracetamol in the Treatment of Acute Renal Colic – European Urology (free) (via @KariTikkinen and @EUplatinum)
“In kidney stone–related acute pain episodes in patients with adequate renal function, treatment with nonsteroidal anti-inflammatory drugs offers effective and most sustained pain relief, with fewer side effects, when compared with opioids or paracetamol”.
Comprehensive assessment when older people are in hospital improves their chances of getting home and living independently
26 Nov, 2017 | 00:19h | UTCComprehensive assessment when older people are in hospital improves their chances of getting home and living independently – NIHR Signal (free)
Original article: Comprehensive geriatric assessment for older adults admitted to hospital – Cochrane Library (free summary – $ for full-text) AND News Release: Comprehensive geriatric assessment for older adults admitted to hospital (free)
“Comprehensive assessment when older people are in hospital improves their chances of getting home and living independently” (RT @NIHR_DC see Tweet)
Research: Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension
26 Nov, 2017 | 00:15h | UTC“Initial combination therapy can be recommended for patients with BP >150/95 mm Hg”
Meta-Analysis: Coffee consumption and health
26 Nov, 2017 | 00:14h | UTCEditorial: Coffee gets a clean bill of health (free)
Commentaries: Moderate coffee drinking ‘more likely to benefit health than to harm it’ say experts – The BMJ, via EurekAlert (free) AND Coffee: No Harm, No Foul If Only 4 Cups Daily – MedPage Today (free registration required)
Meta-Analysis: Oxygen therapy for acute myocardial infarction
26 Nov, 2017 | 00:13h | UTCOxygen therapy for acute myocardial infarction: A systematic review and meta-analysis – International Journal of Nursing Studies (link to abstract – $ for full-text)
Source: Supplemental Oxygen Is Associated with Excess Risk for Recurrent Myocardial Infarction – Journal Watch ($)
See related article – “Oxygen Therapy in Suspected Acute Myocardial Infarction” – and commentaries in our August 29th issue (see #1)
“Supplemental Oxygen Associated w/ Excess Risk for Recurrent Myocardial Infarction. It’s time to stop the free flow of oxygen when not absolutely needed” (RT @JWatch see Tweet)
Counting the costs: U.S. hospitals feeling the pain of physician burnout
25 Nov, 2017 | 23:00h | UTCCounting the costs: U.S. hospitals feeling the pain of physician burnout – Reuters (free)
Guideline: Hepatitis B Vaccination, Screening, and Linkage to Care
25 Nov, 2017 | 22:54h | UTCCommentaries: ACP, CDC issue best practice advice on HBV – ACP Internist (free) AND CDC, ACP Offer Joint Guidance on Hepatitis B Vaccination and Screening – Physician’s First Watch (free)
Research: Management of Tiny Unruptured Intracranial Aneurysms
25 Nov, 2017 | 22:53h | UTCEditorial: Leaving Tiny, Unruptured Intracranial Aneurysms Untreated: Why Is It So Hard? (free)
Research: Effects of Sodium Reduction and the DASH Diet in Relation to Baseline Blood Pressure
25 Nov, 2017 | 22:55h | UTCEffects of Sodium Reduction and the DASH Diet in Relation to Baseline Blood Pressure – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: DASH Diet, Sodium, and Baseline Blood Pressure – Latest in Cardiology, American College of Cardiology (free) AND Big BP Reductions When DASH Diet Combined With Low Sodium Intake – TCTMD (free)
Research: Arthroscopic subacromial decompression for subacromial shoulder pain
25 Nov, 2017 | 22:50h | UTCEditorial: No benefit of arthroscopy in subacromial shoulder pain (free)
Commentaries: Common shoulder surgery may offer little pain relief – OnMedica (free) AND Is a common shoulder surgery useless? – MedicalXpress (free) AND Popular Surgery To Ease Chronic Shoulder Pain Called Into Question – NPR (free)
Research: Association of Hormonal Contraception With Suicide Attempts and Suicides
25 Nov, 2017 | 22:51h | UTCAssociation of Hormonal Contraception With Suicide Attempts and Suicides – American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Hormonal Contraception May Increase Risk of Suicide, Study Suggests – Psychiatric News Alert (free) AND Oral Contraceptives Linked to Suicide – Medscape (free registration required)
Guideline for treatment of cancer pain
25 Nov, 2017 | 22:48h | UTC2017 SEOM clinical guideline for treatment of cancer pain – Clinical and Translational Oncology (free)
Research: Cancer cases and deaths attributable to potentially modifiable risk factors
25 Nov, 2017 | 22:47h | UTCCommentaries: Cancer: 42 percent of cases down to risk factors you can change – Medical News Today (free) AND Preventable Cancer Estimate Reaches 40% – MedPage Today (free registration required)
Guideline: Deprescribing antihyperglycemic agents in older persons
25 Nov, 2017 | 22:45h | UTCRelated algorithm: Antihyperglycemic deprescribing algorithm (free PDF)
See also other Deprescribing Guidelines and Algorithms (free resources)
Choosing Wisely: Six Things Pharmacists and Patients Should Question
25 Nov, 2017 | 22:46h | UTCNew Choosing Wisely Canada list: Six Things Pharmacists and Patients Should Question (RT @CPhAAPhC see Tweet)
See more on the Choosing Wisely initiative in our April 5 issue (see #6)
Research: Conjoint Associations of Gestational Diabetes and Hypertension With Diabetes, Hypertension, and Cardiovascular Disease in Parents
25 Nov, 2017 | 22:42h | UTCInvited Commentary: Gestational Hypertension and Diabetes—A Major Public Health Concern (free)
Commentaries: Pregnancy-related conditions taken together leave moms — and dads — at risk – McGill University Health Centre, via EurekAlert (free) AND Gestational Diabetes and Hypertension = Huge Risk for Later Disease – Medscape (free registration required)
Research: Development and validation of a risk prediction algorithm to estimate future risk of type 2 diabetes
25 Nov, 2017 | 22:40h | UTCDevelopment and validation of QDiabetes-2018 risk prediction algorithm to estimate future risk of type 2 diabetes: cohort study – The BMJ (free) (RT @JuliaHCox see Tweet)
See QDiabetes 2018 risk calculator (free)