Internal Medicine

Meta-Analysis: Chemical Venous Thromboembolism Prophylaxis in Neurosurgical Patients

16 Jan, 2018 | 13:13h | UTC

Chemical venous thromboembolism prophylaxis in neurosurgical patients: an updated systematic review and meta-analysis – Journal of Neurosurgery (link to abstract – $ for full-text)

Chemical venous thromboembolism prophylaxis seems to be effective and safe in neurosurgical patients.

Source: EvidenceAlerts

Review: Metabolic Surgery for the Treatment of Type 2 diabetes in Obese Individuals

16 Jan, 2018 | 13:04h | UTC

Metabolic surgery for the treatment of type 2 diabetes in obese individuals – Diabetologia (free)

Research: Triple Antiplatelet Therapy After Acute Cerebral Ischemia

16 Jan, 2018 | 13:00h | UTC

Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial – The Lancet (free)

Commentaries: Learning from TARDIS: time for more focused trials in stroke prevention – The Lancet (free) AND Triple Antiplatelets for Reducing Dependency After Ischaemic Stroke – TARDIS – American College of Cardiology, Latest in Cardiology (free)

“Among patients with recent cerebral ischaemia, intensive antiplatelet therapy did not reduce the incidence and severity of recurrent stroke or TIA, but did significantly increase the risk of major bleeding. Triple antiplatelet therapy should not be used in routine clinical practice”.

Guideline: Prevention of Hepatitis B Virus Infection

16 Jan, 2018 | 12:56h | UTC

Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices – Morbidity and Mortality Weekly Report (MMWR), CDC (free)

Commentary: ACIP: Updated Recommendations for Hepatitis B Virus Infection Prevention – MPR (free)

Review – Phenotyping of Acute Kidney Injury: Beyond Serum Creatinine

16 Jan, 2018 | 12:45h | UTC

Phenotyping of Acute Kidney Injury: Beyond Serum Creatinine – Seminars in Nephrology (free)

Source: Hospital Medicine Virtual Journal Club

Review: Steroids in Sepsis

16 Jan, 2018 | 12:46h | UTC

Steroids in Sepsis – The Bottom Line (free)

Research: Machine Learning Model Predicts Sepsis in ICU Patients up to 12 hours Before Diagnosis

13 Jan, 2018 | 19:08h | UTC

Machine learning model predicts sepsis in ICU patients up to 12 hours before diagnosis – ACP Hospitalist (free)

Original article: An Interpretable Machine Learning Model for Accurate Prediction of Sepsis in the ICU – Critical Care Medicine (link to abstract – $ for full-text)

Systematic Review: Interventions to Reduce the Overuse of Imaging for Pulmonary Embolism

13 Jan, 2018 | 19:04h | UTC

Interventions to Reduce the Overuse of Imaging for Pulmonary Embolism: A Systematic Review – Journal of Hospital Medicine (free PDF)

Commentary: Clinical decision support may be best strategy to reduce imaging for pulmonary embolism – ACP Hospitalist (free)

Current Treatment Algorithms in Hematology

13 Jan, 2018 | 19:02h | UTC

Introducing ‘Current Treatment Algorithms’ – On Medicine Blog (free)

Treatment algorithm 1: Essential thrombocythemia treatment algorithm 2018 – Blood Cancer Journal (free)

Treatment algorithm 2: Polycythemia vera treatment algorithm 2018 – Blood Cancer Journal (free)

Research: Endoscopic or Surgical Step-up Approach for Infected Necrotising Pancreatitis

13 Jan, 2018 | 19:01h | UTC

Endoscopic or surgical step-up approach for infected necrotising pancreatitis: a multicentre randomised trial – The Lancet (link to abstract – $ for full-text)

Commentary: Endoscopic vs Surgical Step-Up Approach for Treating Infected Necrotizing Pancreatitis – PracticeUpdate (free registration required)

Research: Malnutrition Diagnosis during Adult Inpatient Hospitalizations

12 Jan, 2018 | 16:29h | UTC

Malnutrition Diagnosis during Adult Inpatient Hospitalizations: Analysis of a Multi-Institutional Collaborative Database of Academic Medical Centers – Journal of the Academy of Nutrition and Dietetics (link to abstract – $ for full-text)

Commentary: Malnutrition remains underdiagnosed, undertreated for decades among hospitalized patients – News Medical (free)

Research: Incremental Effects of Antihypertensive Drugs

12 Jan, 2018 | 16:27h | UTC

Incremental effects of antihypertensive drugs: instrumental variable analysis – The BMJ (free)

Commentary: Addition of new class of antihypertensive drug effective for lowering BP – Clinical Advisor (free)

Guideline: Treatment of Non-neurogenic Male LUTS

10 Jan, 2018 | 23:24h | UTC

Treatment of Non-neurogenic Male LUTS – European Urology Association (free, but not accessible via mobile devices) (via @KariTikkinen)

Review: Non-alcoholic Fatty Liver Disease

10 Jan, 2018 | 23:17h | UTC

Non-alcoholic Fatty Liver Disease: A Clinical Update – Journal of Clinical and Translational Hepatology (free)

Guideline: Pharmacological Treatment of Patients With Alcohol Use Disorder

10 Jan, 2018 | 23:18h | UTC

The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder (free)

News release: APA Releases New Practice Guideline on Treatment of Alcohol Use Disorder – American Psychiatry Association (free)

Commentary: New Alcohol Use Disorder Guideline Emphasizes Medication – Medscape (free registration required)

Research: Effect of Physical Activity on Frailty

10 Jan, 2018 | 23:16h | UTC

Effect of Physical Activity on Frailty: Secondary Analysis of a Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Structured exercise may offer mobility benefits to all older patients, regardless of frailty – ACP Internist (free) AND Exercise may reduce disability even in frail elders – Reuters (free) AND Effect of Physical Activity on Frailty – Summary for Patients, Annals of Internal Medicine (free)

Meta-Analysis: Patent Forame Ovale Closure Tied to Lower Risk for Recurrent Stroke

10 Jan, 2018 | 23:15h | UTC

Percutaneous PFO Closure Tied to Lower Risk for Recurrent Stroke – Physician’s First Watch (free) AND Meta-Analyses Support Stroke Prevention With PFO Closure – MedPage Today (free registration required)

Original article 1: Device Closure Versus Medical Therapy Alone for Patent Foramen Ovale in Patients With Cryptogenic Stroke: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Original article 2: Percutaneous Closure Versus Medical Treatment in Stroke Patients With Patent Foramen Ovale: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Research: Silent Myocardial Infarction and Long-Term Risk of Heart Failure

10 Jan, 2018 | 23:12h | UTC

Silent Myocardial Infarction and Long-Term Risk of Heart Failure: The ARIC Study – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Silent MI and the Risk of Heart Failure – American College of Cardiology, Latest in Cardiology (free) AND Silent MI associated with downstream heart failure risk – Cardiovascular Business (free) AND Heart Failure Risk Following ‘Silent’ MI Warrants Scrutiny: ARIC Analysis – TCTMD (free) AND Silent MI Predicts Heart Failure, Deserves More Respect as CHD Risk Factor – Medscape (free registration required)

Prescribing Cascade in a Cardiology Practice

10 Jan, 2018 | 00:31h | UTC

Prescribing Cascade in a Cardiology Practice – American College of Cardiology, Latest in Cardiology (free)

“Before starting a medication to treat a new medical condition, consider whether this condition could be a drug-related adverse event. Specifically, consider whether this could represent a prescribing cascade”.

Richard Lehman’s journal reviews – 8 January 2018

10 Jan, 2018 | 00:23h | UTC

Richard Lehman’s journal reviews, 8 January 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

Giving Oxygen Routinely After a Stroke Does Not Improve Outcomes

10 Jan, 2018 | 00:22h | UTC

Giving oxygen routinely after a stroke does not improve outcomes – NIHR Signal (free)

Original article: Effect of Routine Low-Dose Oxygen Supplementation on Death and Disability in Adults With Acute Stroke: The Stroke Oxygen Study Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

“Let’s Talk TB is a book on the current best practices on TB diagnosis and treatment available for free for all GPs and private practitioners in India and other high-burden countries”

Free Online Course: Antimicrobial Stewardship

8 Jan, 2018 | 00:52h | UTC

New free online course: Antimicrobial Stewardship: A competency-based approach – World Health Organization (via @snahrgang)