Internal Medicine
WHO Guideline: Latent TB Infection
2 Mar, 2018 | 01:59h | UTCNews release: WHO issues new recommendations calling for accelerated uptake of testing and treatment for TB prevention (free)
Guidelines for the Use of Antiplatelet Therapy
2 Mar, 2018 | 01:57h | UTCRelated guidelines: 2017 European Society of Cardiology focused update on dual antiplatelet therapy in coronary artery disease (free) AND 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease (free)
Research: Efficacy of self-monitored blood pressure for titration of antihypertensive medication
2 Mar, 2018 | 01:53h | UTCCommentaries: Hypertension: time for doctors to switch the driver’s seat? (free) AND Should home-based blood pressure monitoring be commonplace in NHS? – University of Oxford News & Events (free)
“Self-monitoring, with or without telemonitoring, when used by general practitioners to titrate antihypertensive medication in individuals with poorly controlled blood pressure, leads to significantly lower blood pressure than titration guided by clinic readings”.
Guideline: pharmacological management of patients with type 2 diabetes and cardiovascular diseases
2 Mar, 2018 | 01:55h | UTCRelated guideline: Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes, 2018 – American Diabetes Association (free)
Meta-Analysis: Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease
2 Mar, 2018 | 01:49h | UTCThis meta-analysis of randomized trials showed CABG had a mortality benefit over PCI in patients with multivessel disease, particularly those with diabetes and higher coronary complexity. There was no mortality benefit in patients with left main disease.
Too Late To Operate? Surgery Near End Of Life Is Common, Costly
2 Mar, 2018 | 01:33h | UTCToo Late To Operate? Surgery Near End Of Life Is Common, Costly – NPR (free)
Meta-Analysis: Can Exercise Improve Cognitive Symptoms of Alzheimer’s Disease?
2 Mar, 2018 | 01:31h | UTCCommentarires: Aerobic exercise may mildly delay, slightly improve Alzheimer’s symptoms – American Geriatrics Society, via EurekAlert (free) AND Aerobic exercise slows cognitive decline in Alzheimer’s disease – Reuters (free)
Review: Medical Management of the Postoperative Bariatric Surgery Patient
2 Mar, 2018 | 01:29h | UTCMedical Management of the Postoperative Bariatric Surgery Patient – Endotext (free)
Related Guideline: Practical Recommendations of the Obesity Management Task Force of the European Association for the Study of Obesity for the Post-Bariatric Surgery Medical Management (free)
Review: Cancer Diagnosis in Patients with Heart Failure
2 Mar, 2018 | 01:24h | UTCRelated Guidelines and Reviews: Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines (free) AND Canadian Cardiovascular Society Guidelines for Evaluation and Management of Cardiovascular Complications of Cancer Therapy (free) AND Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management – CA: A Cancer Journal for Clinicians (free)
Research: Primary Care Physicians’ Work in the Electronic Health Record Era
2 Mar, 2018 | 01:21h | UTCCommentary: EHR Time Exceeds Patient Face Time in Family Practice Visits – Medscape (free registration required)
Related: Care-Centered Clinical Documentation in the Digital Environment: Solutions to Alleviate Burnout – National Academy of Medicine (free) AND Date Night with the EHR – NEJM Catalyst (free) AND Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free) AND Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians(free)
Research: Measures of General and Central Adiposity and the Risk of Myocardial Infarction
2 Mar, 2018 | 01:19h | UTCSex Differences in the Association Between Measures of General and Central Adiposity and the Risk of Myocardial Infarction: Results From the UK Biobank – Journal of the American Heart Association (free for a limited period)
Commentaries: Wait and hip measurement better indicator of heart attack risk than obesity – OnMedica (free) AND Larger waist, hips may raise women’s heart attack risk – MedicalNewsToday (free)
Meta-Analysis: Comparative Effectiveness and Safety of Cognitive Enhancers for Treating Alzheimer’s Disease
2 Mar, 2018 | 01:23h | UTCSource: Medscape (free registration required)
“Cognitive enhancers in general have minimal effects on cognition according to minimal clinically important difference and global ratings. The drugs appear safe, but this must be interpreted cautiously because trial participants may have less comorbidity and fewer adverse effects than those treated with these drugs in clinical practice”.
Research: Association of Varicose Veins With Incident Venous Thromboembolism and Peripheral Artery Disease
2 Mar, 2018 | 01:20h | UTCAssociation of Varicose Veins With Incident Venous Thromboembolism and Peripheral Artery Disease – JAMA (link to abstract – $ for full-text)
Commentaries: Patients with varicose veins at greater risk for thrombosis, other vascular diseases – Cardiovascular Business (free) AND Varicose Veins Linked to Greater Risk for VTE, PAD – NEJM Physician’s First Watch (free) AND Varicose Veins May Increase Likelihood of Blood Clots – Physician’s Weekly (free)
Guidelines for the Pharmacological Treatment of Social Anxiety Disorder
2 Mar, 2018 | 01:17h | UTCRelated guideline: Social anxiety disorder: recognition, assessment and treatment – NICE (free) AND Summary: Recognition, assessment and treatment of social anxiety disorder: summary of NICE guidance – The BMJ (free)
Research: Impact of frailty on outcomes after discharge in older surgical patients
2 Mar, 2018 | 01:18h | UTCCommentary: Frailty associated with readmission risk and postdischarge mortality in older surgical patients – ACP Hospitalist (free)
Related Systematic Review: Identifying older adults at risk of harm following elective surgery: a systematic review and meta-analysis – BMC Medicine (free) AND Commentary: Age itself is not a risk factor for complications after surgery among older patients – OnMedica (free)
Research: Patterns and Predictors of Short-Term PICCs Use
2 Mar, 2018 | 01:15h | UTCPatterns and Predictors of Short-Term Peripherally Inserted Central Catheter Use: A Multicenter Prospective Cohort Study – Journal of Hospital Medicine (free PDF)
Commentary: Short-term use of IV devices is common — and risky — study shows – University of Michigan, via ScienceDaily (free)
“Intravenous devices known as PICCs should be reserved for long-term use, but a new study shows 1 in 4 are used for 5 days or less” (from ScienceDaily)
Systematic Review: Interventions for paracetamol (acetaminophen) overdose
2 Mar, 2018 | 01:01h | UTCInterventions for paracetamol (acetaminophen) overdose – Cochrane Library (free)
Original article: Interventions for paracetamol (acetaminophen) overdose – Cochrane Library (link to abstract – $ for full-text)
Richard Lehman’s journal review – 26 February 2018
2 Mar, 2018 | 01:00h | UTCRichard Lehman’s journal review, 26 February 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Research: Bariatric Surgery Associated With Reduced Need For Diabetes Medications 6 Years Later
2 Mar, 2018 | 01:10h | UTCAssociation Between Bariatric Surgery and Rates of Continuation, Discontinuation, or Initiation of Antidiabetes Treatment 6 Years Later – JAMA Surgery (link to abstract – $ for full-text)
Commentaries: Bariatric Surgery Associated With Reduced Need For Diabetes Medications at Six Years – MedicalResearch (free) AND Roughly Half of Obese Patients Who Have Bariatric Surgery Are Off Type 2 Diabetes Meds at 6 Years – TCTMD (free)
See related studies on the long-term effects of Bariatric Surgery in our January 17th issue (see #1, #2 and #3)
Research: Effect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients
2 Mar, 2018 | 00:57h | UTCEffect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients: The PROPER Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Pulmonary Embolism Rule-out Criteria non-inferior to usual care for patients at low-risk for pulmonary embolism – 2 Minute Medicine (free) AND EM Nerd-The Case of the Diagnostic Absurdity (free) AND Using PERC & Sending Home Pulmonary Emboli For Fun and Profit – Emergency Literature of Note (free)
FDA Safety Alert: Clarithromycin Associated with Increased Risk of Heart Problems or Death in Patients With Heart Disease
2 Mar, 2018 | 00:59h | UTCFDA Safety Alert: Clarithromycin (Biaxin): Drug Safety Communication – Potential Increased Risk of Heart Problems or Death in Patients With Heart Disease (free)
Commentaries: FDA: Antibiotic Linked to Increased Risk of Death in Heart Disease Patients – MPR (free) AND FDA: Clarithromycin Risks Persist in Patients With CAD – TCTMD (free) FDA Alert: Clarithromycin Risky in Patients With Heart Disease – Medscape (free registration required)
Research: Spironolactone Vs Clonidine for Resistant Hypertension
2 Mar, 2018 | 00:54h | UTCCommentary: Spironolactone bests clonidine as fourth drug for resistant hypertension – Univadis (free registration required)
An Evidence-Based Approach to Pressors in Shock
1 Mar, 2018 | 22:12h | UTCAn Evidence-Based Approach to Pressors in Shock: Part I – emDocs (free)
An Evidence-Based Approach to Pressors in Shock: Part II – emDocs (free)
An Overview of Meta-analysis for Clinicians
1 Mar, 2018 | 22:11h | UTCAn overview of meta-analysis for clinicians – Korean Journal of Internal Medicine (free)
Review: Transcatheter versus surgical aortic valve replacement in severe, symptomatic aortic stenosis
1 Mar, 2018 | 21:58h | UTC