Internal Medicine
Systematic Reviews: Red Blood Cell Transfusion to Treat or Prevent Complications in Sickle Cell Disease
11 Aug, 2018 | 02:14h | UTCRed blood cell transfusion to treat or prevent complications in sickle cell disease: an overview of Cochrane reviews – Cochrane Library (link to abstract – $ for full-text)
Summary: An overview of Cochrane Reviews on red blood cell transfusions to treat or prevent sickle cell disease-related complications – Cochrane Library (free)
Cohort Study: Microvascular Outcomes in Patients With Diabetes After Bariatric Surgery Versus Usual Care
11 Aug, 2018 | 02:13h | UTCMicrovascular Outcomes in Patients With Diabetes After Bariatric Surgery Versus Usual Care: A Matched Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Bariatric Surgery for Diabetes May Halve the Risk for Microvascular Disease – NEJM Physician’s First Watch (free) AND Bariatric surgery linked to significant reduction in microvascular complications of type 2 diabetes – MedicalXpress (free)
Cohort Study: Comparison of Clinical Outcomes Among Patients With Atrial Fibrillation or Atrial Flutter
11 Aug, 2018 | 02:09h | UTCCommentaries: Ischemic Stroke Risk Scoring May Not Be Accurate for Patients with Atrial Flutter – TCTMD (free) AND Don’t Group Afib, Atrial Flutter Together in Evaluating Stroke Risk – MedPage Today (free registration required)
The Surviving Sepsis Campaign: A Rush to Judgment
11 Aug, 2018 | 02:07h | UTCThe Surviving Sepsis Campaign: A Rush to Judgment – NEJM Journal Watch (free)
Original Guideline: The Surviving Sepsis Campaign Bundle: 2018 update – Intensive Care Medicine (free)
Related Opinion: Petition to retire the surviving sepsis campaign guidelines – PulmCrit (free)
The Illness Is Bad Enough. The Hospital May Be Even Worse
11 Aug, 2018 | 02:04h | UTCThe Illness Is Bad Enough. The Hospital May Be Even Worse – The New York Times (10 articles per month are free)
Related: Post-Hospital Syndrome — An Acquired, Transient Condition of Generalized Risk – New England Journal of Medicine (free) AND Is Posthospital Syndrome a Result of Hospitalization-Induced Allostatic Overload? – Journal of Hospital Medicine (free) (via @hmkyale)
“The elderly are particularly vulnerable to “post-hospital syndrome,” some experts believe, and that may be why so many patients return.”
Systematic Review: Colloids vs Crystalloids for Fluid Resuscitation in Critically Ill People
11 Aug, 2018 | 02:02h | UTCColloids versus crystalloids for fluid resuscitation in critically ill people – Cochrane Library (link to abstract – $ for full-text)
Summary: Colloids or crystalloids for fluid replacement in critically people – Cochrane Library (free)
“Using starches, dextrans, albumin or FFP (moderate-certainty evidence), or gelatins (low-certainty evidence), versus crystalloids probably makes little or no difference to mortality. Starches probably slightly increase the need for blood transfusion and RRT (moderate-certainty evidence), and albumin or FFP may make little or no difference to the need for renal replacement therapy (low-certainty evidence)”.
Guideline: Management of Heart Failure 2018
3 Aug, 2018 | 11:51h | UTC
Guideline: Management of Atrial Fibrillation 2018
3 Aug, 2018 | 11:50h | UTC
The Top 10 Pulmonary Pearls for Primary Care Physicians
3 Aug, 2018 | 11:49h | UTCThe Top 10 Pulmonary Pearls for Primary Care Physicians – Mayo Clinic Proceedings (free for a limited period)
Study: Prospective Validation of the 0/1-h Algorithm for Early Diagnosis of Myocardial Infarction
3 Aug, 2018 | 11:42h | UTCProspective Validation of the 0/1-h Algorithm for Early Diagnosis of Myocardial Infarction – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Validation of ESC 0/1-h Algorithm for MI – American College of Cardiology (free) AND ESC Algorithm Safely Rules Out NSTEMI, But Caution May Be Warranted in the US – TCTMD (free)
Related Review: High-Sensitivity Cardiac Troponin in the Evaluation of Possible AMI – American College of Cardiology (free)
Randomized Trials: Rifampin vs. Isoniazid for Latent TB
3 Aug, 2018 | 11:44h | UTCRelated Article: Safety and Side Effects of Rifampin versus Isoniazid in Children – New England Journal of Medicine (free)
Quick Take Video Summary: Rifampin or Isoniazid for Latent Tuberculosis (free)
Commentaries: New tuberculosis treatment could help tackle global epidemic – The Guardian (free) AND Rifampin Promising for Latent TB in Phase 3 Trials – Medscape (free registration required)
Randomized Trial: Preoperative Angiotensin-Converting Enzyme Inhibition and Outcomes
3 Aug, 2018 | 11:42h | UTCCommentary: Omitting ACE inhibitor before surgery reduced intraoperative hypotension, study finds – ACP Hospitalist (free)
Cohort Study: Association of Orthostatic Hypotension with Cognitive Decline
3 Aug, 2018 | 11:40h | UTCAssociation of orthostatic hypotension with incident dementia, stroke, and cognitive decline – Neurology (link to abstract – $ for full-text)
Commentary: People who frequently feel dizzy on standing ‘at future risk of dementia’ – NHS Choices (free)
Related Research: Orthostatic hypotension and symptomatic subclinical orthostatic hypotension increase risk of cognitive impairment: an integrated evidence review and analysis of a large older adult hypertensive cohort – European Heart Journal (free)
Evidence Synopsis: Aspirin Plus Clopidogrel vs Aspirin Alone for Patients at High Risk for Cardiovascular Events
3 Aug, 2018 | 11:36h | UTCAspirin Plus Clopidogrel vs Aspirin Alone for Preventing Cardiovascular Events Among Patients at High Risk for Cardiovascular Events – JAMA (free for a limited period)
“Clopidogrel+ASA: Reduced risk for MI and ischemic stroke – Increased risk for major bleeding compared with aspirin alone. Combined therapy is NOT associated with lower mortality.” (via @ehlJAMA see Tweet)
Cohort Study: Risk Factors for Prosthetic Joint Infection After Hip Replacement
3 Aug, 2018 | 11:35h | UTCCommentaries: Risk factors in septic revisions following total hip arthroplasty – The Lancet Infectious Diseases (free) AND Several factors associated with hip replacement revision due to prosthetic joint infection – ACP Internist Weekly (free)
Choosing Wisely: Recommendations from the Society for the Advancement of Blood Management
3 Aug, 2018 | 11:34h | UTCSociety for the Advancement of Blood Management: Five Things Physicians and Patients Should Question (free)
Commentary: Choosing Wisely: Five Anemia, Transfusion Practices to Avoid – Physician’s First Watch (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Review: Management of Bilateral Adrenal Incidentalomas
3 Aug, 2018 | 11:31h | UTC
Perspective: Assisted Suicide is Controversial, but Palliative Sedation is Legal and Offers Peace
3 Aug, 2018 | 11:32h | UTC
Consensus Statement: Antithrombotic Therapy in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Undergoing PCI
3 Aug, 2018 | 11:30h | UTCCommentary: New Consensus Statement: NOAC and Clopidogrel for Most A-fib Patients Treated With PCI – TCTMD (free)
Study: Association of Statin Exposure With Idiopathic Inflammatory Myositis
3 Aug, 2018 | 11:29h | UTCAssociation of Statin Exposure With Histologically Confirmed Idiopathic Inflammatory Myositis in an Australian Population – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Rare Inflammatory Muscle Inflammation Increased With Statin Exposure – MedicalResearch.com (free) AND Statin Associated with an Increase in Inflammatory Myopathy – RheumNow (free) AND Statin use may increase risk for idiopathic inflammatory myositis – Healio (free registration required)
AAFP Guideline: PSA-Based Prostate Cancer Screening in Men Aged 55-69
3 Aug, 2018 | 04:07h | UTCPSA-Based Prostate Cancer Screening in Men Aged 55-69 – American Academy of Family Physicians (free)
News Release: AAFP Updates Its PSA Screening Recommendation (free)
Related Guidelines with conflicting viewpoints: American Cancer Society Guideline for the Early Detection of Prostate Cancer (free) AND USPSTF Recommendation Statement: Screening for Prostate Cancer (free guideline, editorial and commentaries)
AHA Scientific Advisory: Limit Low-calorie Sodas and Drinks
3 Aug, 2018 | 04:09h | UTCNews Release: Limit low-calorie sodas and drinks, and stick to water instead, researchers advise (free)
Richard Lehman’s Journal Reviews, 30 July 2018
3 Aug, 2018 | 04:04h | UTCRichard Lehman’s journal reviews, 30 July 2018 – The BMJ Opinion (free)
Richard Lehman’s final review of the latest research in the top medical journals.
Meta-Analysis: Ketamine as an Alternative to Opioids for Acute Pain in the ED
3 Aug, 2018 | 03:58h | UTCA Systematic Review and Meta‐analysis of Ketamine as an Alternative to Opioids for Acute Pain in the Emergency Department – Academic Emergency Medicine (link to abstract – $ for full-text)
Commentaries: Low-Dose Ketamine Offers Effective Alternative to Opioids in Treatment of Acute Pain, Meta-Analysis Suggests – Psychiatric News Alert (free) AND Ketamine vs Opioids for Acute Pain in the Emergency Department – MedicalResearch.com (free) AND Low-Dose Ketamine May Be a Safe Opioid Alternative, Review Confirms – Medscape (free registration required) AND Ketamine could help reduce opioid use in the ER – Medical News Today (free)
Randomized Trial: Magnesium for the Management of Rapid Atrial Fibrillation
3 Aug, 2018 | 03:59h | UTCLOw dose MAGnesium sulfate versus HIgh dose in the early management of rapid atrial fibrillation: randomised controlled double blind study – Academic Emergency Medicine (link to abstract – $ for full-text)
Commentaries: Low-dose vs. High-dose Magnesium in Rapid Afib – The PharmERToxGuy (free) AND Magnesium to treat rapid Afib in the ED – Univadis (free registration required)