Internal Medicine

Randomized Trial: Low-Dose Imipramine for Refractory Functional Dyspepsia

30 Nov, 2018 | 02:57h | UTC

Low-dose imipramine for refractory functional dyspepsia: a randomised, double-blind, placebo-controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: Low-Dose Imipramine Alternative Treatment for Refractory Functional Dyspepsia – Clinical Advisor (free)

 

---

Study: Cardiovascular Toxicities Associated with Immune Checkpoint Inhibitors

30 Nov, 2018 | 02:56h | UTC

Cardiovascular toxicities associated with immune checkpoint inhibitors: an observational, retrospective, pharmacovigilance study – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: Cardiovascular Toxicities Associated With Immune Checkpoint Inhibitor Treatment – The ASCO Post (free)

Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)

Related Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)

 

---

Guideline: Diagnosis and Management of Polycythaemia Vera

30 Nov, 2018 | 02:51h | UTC

A guideline for the diagnosis and management of polycythaemia vera. A British Society for Haematology Guideline (free)

 

---

New ASH Clinical Practice Guidelines on Venous Thromboembolism

30 Nov, 2018 | 02:53h | UTC

ASH Clinical Practice Guidelines on Venous Thromboembolism – American Society of Hematology (free)

News Release: New clinical practice guidelines for venous thromboembolism (free)

 

---

Systematic Review: Prolonged Thromboprophylaxis for Abdominal or Pelvic Surgery

30 Nov, 2018 | 02:48h | UTC

Prolonged thromboprophylaxis with low molecular weight heparin for abdominal or pelvic surgery – Cochrane Library (free)

Summary: Do blood thinner injections given after abdominal surgery further reduce blood clots if continued after discharge from the hospital? – Cochrane Library (free)

 

---

ACP Position Statement: Principles for Patient and Family Partnership in Care

30 Nov, 2018 | 02:52h | UTC

Principles for Patient and Family Partnership in Care: An American College of Physicians Position Paper – Annals of Internal Medicine (free)

News Release: American College of Physicians releases principles to guide patient partnership in health care (free)

 

---

Study: Screenning for Colorectal Cancer with FOBT Only Effective in Men

30 Nov, 2018 | 02:41h | UTC

Sex differences in faecal occult blood test screening for colorectal cancer – British Journal of Surgery (free)

Commentaries: Screen­ing for colorectal can­cer spares male pa­tients from in­tense treat­ments – University of Helsinki (free) AND FOBT Colorectal Cancer Screening Only Effective in Men – Medscape (free registration required)

 

---

Review: Therapy and Management of Pneumocystis Jirovecii

30 Nov, 2018 | 02:39h | UTC

Therapy and Management of Pneumocystis jirovecii – Infection – Journal of Fungi (free)

This article belongs to the Special Issue Treatments for Fungal Infections (free reviews)

 

---

Review: Arterial Thrombosis in Unusual Sites

30 Nov, 2018 | 02:38h | UTC

Arterial thrombosis in unusual sites: A practical review – European Journal of Haematology (free)

 

---

NICE Guideline: Catheter-Associated Urinary Tract Infection

30 Nov, 2018 | 02:27h | UTC

Urinary tract infection (catheter-associated): antimicrobial prescribing – National Institute for Health and Care Excellence (free)

Related: NICE Antimicrobial Prescribing Guidelines (free guidelines and resources)

 

---

Guideline: Febrile Neutropenia in Adults with Solid Tumors

30 Nov, 2018 | 02:25h | UTC

SEOM clinical practice guideline: management and prevention of febrile neutropenia in adults with solid tumors (2018) – Clinical and Translational Oncology (free)

Related: Guideline: Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy (free guidelines on the subject)

 

---

Podcast: STIs: Syphilis, Gonorrhea and Chlamydia

30 Nov, 2018 | 01:59h | UTC

#127 STIs: Syphilis, Gonorrhea and Chlamydia – The Curbsiders Internal Medicine Podcast (free)

 

---

Acute Liver Failure: Evidence-Based Evaluation and Management

30 Nov, 2018 | 01:55h | UTC

Acute Liver Failure: Evidence-Based Evaluation and Management – emDocs (free)

 

---

Ann Robinson’s Research Reviews – 26 November 2018

30 Nov, 2018 | 01:57h | UTC

Ann Robinson’s research reviews, 26 November 2018 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 

---

Guideline Synopsis: Diagnosis and Management of Nonalcoholic Liver Disease

30 Nov, 2018 | 01:56h | UTC

Diagnosis and Management of Nonalcoholic Liver Disease – JAMA (free for a limited period)

 

---

AAPT Diagnostic Criteria for Fibromyalgia

30 Nov, 2018 | 01:53h | UTC

AAPT Diagnostic Criteria for Fibromyalgia – The Journal of Pain (free)

Related Guidelines: EULAR revised recommendations for the management of fibromyalgia (free) AND Canadian Guidelines for the diagnosis and management of fibromyalgia syndrome: Executive summary (free)

 

---

ACC Expert Consensus: Novel Therapies for CV Risk Reduction in Patients with Type 2 Diabetes

30 Nov, 2018 | 01:54h | UTC

2018 ACC Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease – Journal of the American College of Cardiology (free)

 

---

Cohort Study: Anxiety, Depression and Post Traumatic Stress Disorder After Critical Illness

30 Nov, 2018 | 01:49h | UTC

Anxiety, Depression and Post Traumatic Stress Disorder after critical illness: a UK-wide prospective cohort study – Critical Care (free)

Commentaries: Over half of former ICU patients in the UK report symptoms of psychological disorders – BioMed Central (free) AND ICU stay can lead to depression – Reuters (free)

 

---

Systematic Review: Effect of Testing for Cancer in People with Unprovoked VTE

30 Nov, 2018 | 01:46h | UTC

Effect of testing for cancer on cancer‐ or venous thromboembolism (VTE)‐related mortality and morbidity in people with unprovoked VTE – Cochrane Library (free)

Summary: Effect of testing for cancer (on cancer and blood clot-related death and illness) in people with unprovoked blood clots in the legs and lungs – Cochrane Library (free)

 

---

Review: Diagnosis and Management of Primary Biliary Cholangitis

30 Nov, 2018 | 01:44h | UTC

Diagnosis and Management of Primary Biliary Cholangitis – The American Journal of Gastroenterology (free)

Related Guidelines: Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases – Hepatology (free) AND The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines – Gut (free)

 

---

Review: Cannabinoids for Chronic Pain

30 Nov, 2018 | 01:45h | UTC

Cannabinoids for Chronic Pain – Therapeutics Initiative (free)

Related: Meta-Analysis: Cannabinoids for the Treatment of Chronic Noncancer Pain Conditions (free) AND Guideline for Prescribing Medical Cannabinoids in Primary Care (free article and commentary)

“At the present time we lack good evidence that any cannabis-derived product works for chronic pain”

 

---

Review: Antithrombotic Therapies for Elderly Patients

30 Nov, 2018 | 01:35h | UTC

Antithrombotic therapies for elderly patients: handling problems originating from their comorbidities – Clinical Interventions in Aging (free)

 

---

Review: Non-Cystic Fibrosis Bronchiectasis in the Elderly

30 Nov, 2018 | 01:34h | UTC

Non-cystic fibrosis bronchiectasis in the elderly: current perspectives – Clinical Interventions in Aging (free)

 

---

Review: H. Pylori Infection and Extra-Gastroduodenal Diseases

30 Nov, 2018 | 01:32h | UTC

H. Pylori infection and extra-gastroduodenal diseases – Journal of Biomedical Science (free)

 

---

NCCN Guideline: Cancer-Associated Venous Thromboembolic Disease

25 Nov, 2018 | 20:42h | UTC

NCCN Guidelines Insights: Cancer-Associated Venous Thromboembolic Disease, Version 2.2018 – Journal of the National Comprehensive Cancer Network (free)

 

---